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The map label for this gene is aroE [H]

Identifier: 91790335

GI number: 91790335

Start: 4758436

End: 4759263

Strand: Reverse

Name: aroE [H]

Synonym: Bpro_4503

Alternate gene names: 91790335

Gene position: 4759263-4758436 (Counterclockwise)

Preceding gene: 91790336

Following gene: 91790334

Centisome position: 91.52

GC content: 65.22

Gene sequence:

>828_bases
GTGGGGGCCACATCTCTTTATGCCGTCATTGGCAACCCCATCCAGCAGAGCAAATCGCCGCTGATCCACGGCATGTTTGC
GCAAGCCACAGGGCAAGACATTGAATACACCGCGATCGAGGGGCCATCGGGTGGCTTCGCGGGTGCTGTCGATGCTTTCC
GCGCTGCGGGCGGCCTGGGCCTGAACATCACTGCGCCATTCAAGCTCGACGCCTTTGCCTACGCCACCGAACGCTCCGCG
CGGGCGCAGCTCGCCGGTGCCGTCAATGCCTTGAAATTTGACGGAGACCGCGTGCTGGCCGAGAACTTCGACGGTGTCGG
CCTGGTGCGCGACGTGACCCATAACCTGGGCTGCCCGCTGAAGGGCAAACGCGTGTTGCTGCTGGGTGCTGGTGGCGCAG
CCCGAGGCGCGCTGCTGCCCCTCCTGGAGCAGGCACCGGCAGAGCTGGTGATCGCCAACCGCAGCGTGGACAAGGCACTG
GAGCTGGCAAAAATTGGCGCGGCCAGAGGTAAGGTGCGGGGCTGTGCCTACACCGACCTGGTCGGGCAAACCTTTGATGT
GGTGTTCAACGCCACCTCGGCCAGCCTGCGTGCCGAGCTGCCGCCGGTACCGGCCGGCGTATTTTCCAATTGCGCCCTGG
CGTATGAGCTGGCGTATGGCAAGGGCCTGACGCCCTTCCTGCGCCTGGCGCAAAACGCTGGCGTCAAACAGCTGGCCGAC
GGTGTGGGCATGCTGGCCGAGCAGGCCGCCGAAGCTTTTGCCTGGTGGCGTGGCGTGCGTCCCGACACCCTTGCGGTGAT
CGGGAAGCTGACGGTTCCGCTGGTGTAA

Upstream 100 bases:

>100_bases
AGTCACAAACATGACTACTGCCGCAGCGCCGGGCCGCCCCAAGCAAGGCACGGCCCCTTTTTCCAATGATAGGGGCAGCG
TATTACGCGAAGCGAAAAGC

Downstream 100 bases:

>100_bases
ATAACCGGCTGTCGTGCGCTGTCCAACCCTTCCGGATGACCCCTTCCATGTGCTGCACCGGCCCTCTATACTTCGGGAAT
GAACGAGTTAGTACATTCCG

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MGATSLYAVIGNPIQQSKSPLIHGMFAQATGQDIEYTAIEGPSGGFAGAVDAFRAAGGLGLNITAPFKLDAFAYATERSA
RAQLAGAVNALKFDGDRVLAENFDGVGLVRDVTHNLGCPLKGKRVLLLGAGGAARGALLPLLEQAPAELVIANRSVDKAL
ELAKIGAARGKVRGCAYTDLVGQTFDVVFNATSASLRAELPPVPAGVFSNCALAYELAYGKGLTPFLRLAQNAGVKQLAD
GVGMLAEQAAEAFAWWRGVRPDTLAVIGKLTVPLV

Sequences:

>Translated_275_residues
MGATSLYAVIGNPIQQSKSPLIHGMFAQATGQDIEYTAIEGPSGGFAGAVDAFRAAGGLGLNITAPFKLDAFAYATERSA
RAQLAGAVNALKFDGDRVLAENFDGVGLVRDVTHNLGCPLKGKRVLLLGAGGAARGALLPLLEQAPAELVIANRSVDKAL
ELAKIGAARGKVRGCAYTDLVGQTFDVVFNATSASLRAELPPVPAGVFSNCALAYELAYGKGLTPFLRLAQNAGVKQLAD
GVGMLAEQAAEAFAWWRGVRPDTLAVIGKLTVPLV
>Mature_274_residues
GATSLYAVIGNPIQQSKSPLIHGMFAQATGQDIEYTAIEGPSGGFAGAVDAFRAAGGLGLNITAPFKLDAFAYATERSAR
AQLAGAVNALKFDGDRVLAENFDGVGLVRDVTHNLGCPLKGKRVLLLGAGGAARGALLPLLEQAPAELVIANRSVDKALE
LAKIGAARGKVRGCAYTDLVGQTFDVVFNATSASLRAELPPVPAGVFSNCALAYELAYGKGLTPFLRLAQNAGVKQLADG
VGMLAEQAAEAFAWWRGVRPDTLAVIGKLTVPLV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=269, Percent_Identity=45.3531598513011, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI1787983, Length=285, Percent_Identity=30.5263157894737, Blast_Score=95, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=284, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28420; Mature: 28289

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATSLYAVIGNPIQQSKSPLIHGMFAQATGQDIEYTAIEGPSGGFAGAVDAFRAAGGLG
CCCCEEEHHHCCHHHHCCCCHHEEHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
LNITAPFKLDAFAYATERSARAQLAGAVNALKFDGDRVLAENFDGVGLVRDVTHNLGCPL
EEEECCCEECHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHHHCCCCC
KGKRVLLLGAGGAARGALLPLLEQAPAELVIANRSVDKALELAKIGAARGKVRGCAYTDL
CCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHH
VGQTFDVVFNATSASLRAELPPVPAGVFSNCALAYELAYGKGLTPFLRLAQNAGVKQLAD
HCCCEEEEEECCCHHHEECCCCCCCHHHHCHHEEEEECCCCCCHHHHHHHHCCCHHHHHH
GVGMLAEQAAEAFAWWRGVRPDTLAVIGKLTVPLV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
GATSLYAVIGNPIQQSKSPLIHGMFAQATGQDIEYTAIEGPSGGFAGAVDAFRAAGGLG
CCCEEEHHHCCHHHHCCCCHHEEHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCC
LNITAPFKLDAFAYATERSARAQLAGAVNALKFDGDRVLAENFDGVGLVRDVTHNLGCPL
EEEECCCEECHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCHHHHHHHHCCCCC
KGKRVLLLGAGGAARGALLPLLEQAPAELVIANRSVDKALELAKIGAARGKVRGCAYTDL
CCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHH
VGQTFDVVFNATSASLRAELPPVPAGVFSNCALAYELAYGKGLTPFLRLAQNAGVKQLAD
HCCCEEEEEECCCHHHEECCCCCCCHHHHCHHEEEEECCCCCCHHHHHHHHCCCHHHHHH
GVGMLAEQAAEAFAWWRGVRPDTLAVIGKLTVPLV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA