| Definition | Polaromonas sp. JS666 chromosome, complete genome. |
|---|---|
| Accession | NC_007948 |
| Length | 5,200,264 |
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The map label for this gene is fabG [H]
Identifier: 91789164
GI number: 91789164
Start: 3503377
End: 3504108
Strand: Direct
Name: fabG [H]
Synonym: Bpro_3307
Alternate gene names: 91789164
Gene position: 3503377-3504108 (Clockwise)
Preceding gene: 91789163
Following gene: 91789165
Centisome position: 67.37
GC content: 65.85
Gene sequence:
>732_bases ATGACCCCTCCCCTCAAACGCGCACTTGTCACCGGCGGCAGCGGCGGCATCGGCTCGGCCATCTGCCGGCGCCTGGCGGC CGACGGCTTCAGCGTCATTGTTCATGCCAACAGCCATCTGGCCACGGCGCAGGCCGTGGCGGCCAGCATCGCGGCCGACG GCGGTCAGGCGCAGGCCGTGGCTTTTGATGTCACCGATGCGTCCGCCACGGCGGCGGCGCTCGAGTCCCTGCTCGAACAG GGGCCCATCCAGGTGCTGGTCAACAACGCCGGCATCCACGACGACGCCGTGTTCCCCGGCATGCAGCTGTCCCAATGGCA GCGCGTGCTCGATGTGTCGCTCAACGGCTTTTTCCATGTCACCCAACCCCTGACGCTGCCGATGATACGGACCCGCTGGG GCCGCATCATCACCATCACCTCTGTGGCCGCCGTGGCCGGCAATCGGGGCCAGGTCAACTATTCGGCGGCCAAGGGAGCC CTGCACGCCGCCACCAAATCGCTGGCCCTCGAAGTAGCCAGCCGCGGCATCACGGTCAATGCCGTGGCGCCGGGCATCAT TGACACGGCCATGAGCAATAGCAGCTTCAGTGCTGACGTCATCGAACGCATGGTGCCGATGAAGCGGGCCGGCAAGGCCG AAGAAGTGGCTGACCTCGTGGGCTTTTTGGCCTCGGAACGCGCGGCCTACATCAGCGGGCAGATCATTTCCATCAATGGC GGCATGATCTGA
Upstream 100 bases:
>100_bases GCGCGCGGTTGTCGTGCTCGATGCGGCCCTGCTGCCGAGTCCCGTCAACAGCAGCGGCGGCAGCGCGGGCTGAACCAGCC GGCCCTTCAAGGACACCTTC
Downstream 100 bases:
>100_bases CCCCCGAACCGGCAGTTATCCGCTTGACTGTTTAAAAAGACGTGTAAAACTGGCTGATCCAGCGTCAACGGCAATCACCT CAAGGGGAGAGCACAACGCA
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MTPPLKRALVTGGSGGIGSAICRRLAADGFSVIVHANSHLATAQAVAASIAADGGQAQAVAFDVTDASATAAALESLLEQ GPIQVLVNNAGIHDDAVFPGMQLSQWQRVLDVSLNGFFHVTQPLTLPMIRTRWGRIITITSVAAVAGNRGQVNYSAAKGA LHAATKSLALEVASRGITVNAVAPGIIDTAMSNSSFSADVIERMVPMKRAGKAEEVADLVGFLASERAAYISGQIISING GMI
Sequences:
>Translated_243_residues MTPPLKRALVTGGSGGIGSAICRRLAADGFSVIVHANSHLATAQAVAASIAADGGQAQAVAFDVTDASATAAALESLLEQ GPIQVLVNNAGIHDDAVFPGMQLSQWQRVLDVSLNGFFHVTQPLTLPMIRTRWGRIITITSVAAVAGNRGQVNYSAAKGA LHAATKSLALEVASRGITVNAVAPGIIDTAMSNSSFSADVIERMVPMKRAGKAEEVADLVGFLASERAAYISGQIISING GMI >Mature_242_residues TPPLKRALVTGGSGGIGSAICRRLAADGFSVIVHANSHLATAQAVAASIAADGGQAQAVAFDVTDASATAAALESLLEQG PIQVLVNNAGIHDDAVFPGMQLSQWQRVLDVSLNGFFHVTQPLTLPMIRTRWGRIITITSVAAVAGNRGQVNYSAAKGAL HAATKSLALEVASRGITVNAVAPGIIDTAMSNSSFSADVIERMVPMKRAGKAEEVADLVGFLASERAAYISGQIISINGG MI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=35.4838709677419, Blast_Score=124, Evalue=7e-29, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=33.2, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=32.9059829059829, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=33.4677419354839, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=32.3651452282158, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=29.3388429752066, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4504505, Length=245, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=28.6290322580645, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4503301, Length=219, Percent_Identity=30.1369863013699, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI59889578, Length=176, Percent_Identity=33.5227272727273, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=30.6201550387597, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=32.8042328042328, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=25.3807106598985, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=26.7015706806283, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=9e-12, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=45.2282157676349, Blast_Score=175, Evalue=2e-45, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=36.6255144032922, Blast_Score=133, Evalue=9e-33, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=36.5145228215768, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=34.2741935483871, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=31.1475409836066, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=32.0833333333333, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=33.0708661417323, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=28.2786885245902, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1786812, Length=192, Percent_Identity=31.7708333333333, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=31.3008130081301, Blast_Score=84, Evalue=6e-18, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=37.4501992031873, Blast_Score=143, Evalue=8e-35, Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=36.25, Blast_Score=131, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=33.8842975206612, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=32.1138211382114, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=31.8367346938775, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=32.7935222672065, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.8449612403101, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=30.1158301158301, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=28.90625, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=28.3400809716599, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=34.3915343915344, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=29.0076335877863, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=31.0077519379845, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=30.5019305019305, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=28.90625, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=202, Percent_Identity=30.1980198019802, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.0380228136882, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=30.1158301158301, Blast_Score=80, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=26.5384615384615, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=29.296875, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17508895, Length=235, Percent_Identity=24.2553191489362, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=27.6264591439689, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=30.0395256916996, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=24.4186046511628, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=29.4605809128631, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=230, Percent_Identity=27.3913043478261, Blast_Score=66, Evalue=6e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=35.6, Blast_Score=129, Evalue=1e-30, Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=34.0163934426229, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=32.9166666666667, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=28.1632653061224, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=29.2682926829268, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=30.2040816326531, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=34.4086021505376, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=30.9941520467836, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.9212598425197, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24641232, Length=209, Percent_Identity=29.1866028708134, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR011285 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 24959; Mature: 24828
Theoretical pI: Translated: 7.73; Mature: 7.73
Prosite motif: PS00430 TONB_DEPENDENT_REC_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTPPLKRALVTGGSGGIGSAICRRLAADGFSVIVHANSHLATAQAVAASIAADGGQAQAV CCCCHHHHEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEE AFDVTDASATAAALESLLEQGPIQVLVNNAGIHDDAVFPGMQLSQWQRVLDVSLNGFFHV EEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEE TQPLTLPMIRTRWGRIITITSVAAVAGNRGQVNYSAAKGALHAATKSLALEVASRGITVN CCCCCHHHHHHCCCCEEEEEEHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCEEEE AVAPGIIDTAMSNSSFSADVIERMVPMKRAGKAEEVADLVGFLASERAAYISGQIISING ECCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCEEEEECC GMI CCC >Mature Secondary Structure TPPLKRALVTGGSGGIGSAICRRLAADGFSVIVHANSHLATAQAVAASIAADGGQAQAV CCCHHHHEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEE AFDVTDASATAAALESLLEQGPIQVLVNNAGIHDDAVFPGMQLSQWQRVLDVSLNGFFHV EEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEE TQPLTLPMIRTRWGRIITITSVAAVAGNRGQVNYSAAKGALHAATKSLALEVASRGITVN CCCCCHHHHHHCCCCEEEEEEHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCEEEE AVAPGIIDTAMSNSSFSADVIERMVPMKRAGKAEEVADLVGFLASERAAYISGQIISING ECCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCEEEEECC GMI CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9020051 [H]