Click here to switch to the map view.

The map label for this gene is gcvT [H]

Identifier: 91787747

GI number: 91787747

Start: 1929372

End: 1930568

Strand: Reverse

Name: gcvT [H]

Synonym: Bpro_1868

Alternate gene names: 91787747

Gene position: 1930568-1929372 (Counterclockwise)

Preceding gene: 91787748

Following gene: 91787746

Centisome position: 37.12

GC content: 65.16

Gene sequence:

>1197_bases
ATGGATTCATGTTTGCCCCCGGAGACCGCCTTGTCCAACGCCTCTTCTGCTACCCCCGAAGATCTTCTCAAAACACCGCT
GCATGATCTGCACGTGGAACTCGGCGCGCGCATGGTGCCGTTCGCGGGTTATTCCATGCCGGTGCAGTACCCTGCCGGCC
TGATGGCCGAGCACCACCACACACGTCAGGCGGCAGGCCTTTTTGACGTATCCCACATGGGCCAGCTGCGCCTGGTGGGT
CCTGATTCAGCGGCGGCACTGGAAACCCTGCTGCCTGTCGATGTGATCGACCTGCCGGCGGGCAAGCAGCGCTATGGCCT
GCTGCTCAATGACGACGGCGGCATCATCGACGACCTGATGTTTTTCAACCGCAACATGCACGACAGCGCCAACGGCGGCG
ACCTGTTCCTCATCGTGAACGGCGCCTGCAAGGTCGGCGATATCGCGCACATCCAGCAAAAAATCGGCAGCCGGTGCGAA
GTCATCCCCATGCCCGAGATGGCGTTGATGGCCCTGCAGGGGCCGCAGGCAGTGACGGCCTTGCAGCGCCTGGCACCCGG
TGTTGACAAGCTGGTGTTCATGACCGGCGGCCGTTTCACGGTGGCGGGCTGCGACTGCTTCATCACCCGCAGCGGCTACA
CCGGCGAAGACGGCTTCGAGATCTCGGTGCACGAATCGCAGGCGGACACCCTGGCCAGGGCCCTGCTGGCCCAGTCCGAA
GTCAAACCCGTTGGCCTGGGCGCACGCAACTCGCTGCGGCTCGAAGCCGGCCTGTGCCTGTATGGCAACGACATCGACAC
CAGCACCACGCCGGTGGAAGCGGCGCTCAACTGGGCCATCCAGAAGGTCCGGCGCACTGGCGGCGCGCGGGCCGGCGGAT
TTCCCGGCGCGGAAAAAATTCTGGCGCAACTGGCCGACCCGGCCGCGACACTGACCCGCAAACGCGTGGGACTGGTCGCG
CTGGAACGCGTGCCTGTGCGCGACCACACCGAACTGCAAAGCACGGCGGGCGCACCCATTGGCCAGGTGACCAGCGGCCT
GCTCGGCCCCACCATCAACCAGCCGGTGGCCATGGGCTATGTCAGTCCCGAGTTTGCCGCCATCGGCACGCGAATCCATG
CCCTGGTGCGCGGCAAGCCCGTTCCCATGGAAGTAGCCGCCATGCCGTTTGTGCCCAACCACTACTACCGCGGCTGA

Upstream 100 bases:

>100_bases
GAGACCGCTTTCGAGGCGGCCCACCGAAGGAGCAAGCCTGCATCGCCAGGTGAATCTCTCAGGTAAAGTGGACAGCAGGG
GCAGCGCATGACCATCGGTC

Downstream 100 bases:

>100_bases
GCAACCTACCGACTTTCACTGCCGCCTTTCAAGTTATTCACGTTACTTTTACGTTAACTTGCTGAATCCTTTTCACTGAA
CTTCTGGAGAACCTCATGAC

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDSCLPPETALSNASSATPEDLLKTPLHDLHVELGARMVPFAGYSMPVQYPAGLMAEHHHTRQAAGLFDVSHMGQLRLVG
PDSAAALETLLPVDVIDLPAGKQRYGLLLNDDGGIIDDLMFFNRNMHDSANGGDLFLIVNGACKVGDIAHIQQKIGSRCE
VIPMPEMALMALQGPQAVTALQRLAPGVDKLVFMTGGRFTVAGCDCFITRSGYTGEDGFEISVHESQADTLARALLAQSE
VKPVGLGARNSLRLEAGLCLYGNDIDTSTTPVEAALNWAIQKVRRTGGARAGGFPGAEKILAQLADPAATLTRKRVGLVA
LERVPVRDHTELQSTAGAPIGQVTSGLLGPTINQPVAMGYVSPEFAAIGTRIHALVRGKPVPMEVAAMPFVPNHYYRG

Sequences:

>Translated_398_residues
MDSCLPPETALSNASSATPEDLLKTPLHDLHVELGARMVPFAGYSMPVQYPAGLMAEHHHTRQAAGLFDVSHMGQLRLVG
PDSAAALETLLPVDVIDLPAGKQRYGLLLNDDGGIIDDLMFFNRNMHDSANGGDLFLIVNGACKVGDIAHIQQKIGSRCE
VIPMPEMALMALQGPQAVTALQRLAPGVDKLVFMTGGRFTVAGCDCFITRSGYTGEDGFEISVHESQADTLARALLAQSE
VKPVGLGARNSLRLEAGLCLYGNDIDTSTTPVEAALNWAIQKVRRTGGARAGGFPGAEKILAQLADPAATLTRKRVGLVA
LERVPVRDHTELQSTAGAPIGQVTSGLLGPTINQPVAMGYVSPEFAAIGTRIHALVRGKPVPMEVAAMPFVPNHYYRG
>Mature_398_residues
MDSCLPPETALSNASSATPEDLLKTPLHDLHVELGARMVPFAGYSMPVQYPAGLMAEHHHTRQAAGLFDVSHMGQLRLVG
PDSAAALETLLPVDVIDLPAGKQRYGLLLNDDGGIIDDLMFFNRNMHDSANGGDLFLIVNGACKVGDIAHIQQKIGSRCE
VIPMPEMALMALQGPQAVTALQRLAPGVDKLVFMTGGRFTVAGCDCFITRSGYTGEDGFEISVHESQADTLARALLAQSE
VKPVGLGARNSLRLEAGLCLYGNDIDTSTTPVEAALNWAIQKVRRTGGARAGGFPGAEKILAQLADPAATLTRKRVGLVA
LERVPVRDHTELQSTAGAPIGQVTSGLLGPTINQPVAMGYVSPEFAAIGTRIHALVRGKPVPMEVAAMPFVPNHYYRG

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=399, Percent_Identity=43.859649122807, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI257796258, Length=375, Percent_Identity=43.7333333333333, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI257796254, Length=394, Percent_Identity=41.6243654822335, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI257796256, Length=329, Percent_Identity=42.5531914893617, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI197927446, Length=317, Percent_Identity=26.4984227129338, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI21361378, Length=317, Percent_Identity=26.4984227129338, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI24797151, Length=346, Percent_Identity=24.8554913294798, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789272, Length=380, Percent_Identity=35, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17560118, Length=414, Percent_Identity=39.6135265700483, Blast_Score=238, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6320222, Length=391, Percent_Identity=42.4552429667519, Blast_Score=272, Evalue=9e-74,
Organism=Drosophila melanogaster, GI20129441, Length=401, Percent_Identity=42.3940149625935, Blast_Score=280, Evalue=1e-75,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 42227; Mature: 42227

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSCLPPETALSNASSATPEDLLKTPLHDLHVELGARMVPFAGYSMPVQYPAGLMAEHHH
CCCCCCCHHHHCCCCCCCHHHHHHCCHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHH
TRQAAGLFDVSHMGQLRLVGPDSAAALETLLPVDVIDLPAGKQRYGLLLNDDGGIIDDLM
HHHHHCCEECCCCCCEEEECCCHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHH
FFNRNMHDSANGGDLFLIVNGACKVGDIAHIQQKIGSRCEVIPMPEMALMALQGPQAVTA
HHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHEECCCHHHHH
LQRLAPGVDKLVFMTGGRFTVAGCDCFITRSGYTGEDGFEISVHESQADTLARALLAQSE
HHHHCCCCCEEEEEECCEEEEEEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHC
VKPVGLGARNSLRLEAGLCLYGNDIDTSTTPVEAALNWAIQKVRRTGGARAGGFPGAEKI
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LAQLADPAATLTRKRVGLVALERVPVRDHTELQSTAGAPIGQVTSGLLGPTINQPVAMGY
HHHHCCHHHHHHHHHHCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEE
VSPEFAAIGTRIHALVRGKPVPMEVAAMPFVPNHYYRG
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDSCLPPETALSNASSATPEDLLKTPLHDLHVELGARMVPFAGYSMPVQYPAGLMAEHHH
CCCCCCCHHHHCCCCCCCHHHHHHCCHHHHHHHHCCEEECCCCCCCCCCCCCCHHHHHHH
TRQAAGLFDVSHMGQLRLVGPDSAAALETLLPVDVIDLPAGKQRYGLLLNDDGGIIDDLM
HHHHHCCEECCCCCCEEEECCCHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCHHHHHH
FFNRNMHDSANGGDLFLIVNGACKVGDIAHIQQKIGSRCEVIPMPEMALMALQGPQAVTA
HHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCHHHHHEECCCHHHHH
LQRLAPGVDKLVFMTGGRFTVAGCDCFITRSGYTGEDGFEISVHESQADTLARALLAQSE
HHHHCCCCCEEEEEECCEEEEEEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHC
VKPVGLGARNSLRLEAGLCLYGNDIDTSTTPVEAALNWAIQKVRRTGGARAGGFPGAEKI
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LAQLADPAATLTRKRVGLVALERVPVRDHTELQSTAGAPIGQVTSGLLGPTINQPVAMGY
HHHHCCHHHHHHHHHHCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEE
VSPEFAAIGTRIHALVRGKPVPMEVAAMPFVPNHYYRG
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA