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The map label for this gene is siaT [H]

Identifier: 91787748

GI number: 91787748

Start: 1930844

End: 1932121

Strand: Reverse

Name: siaT [H]

Synonym: Bpro_1869

Alternate gene names: 91787748

Gene position: 1932121-1930844 (Counterclockwise)

Preceding gene: 91787749

Following gene: 91787747

Centisome position: 37.15

GC content: 58.45

Gene sequence:

>1278_bases
ATGACCGCCGCGATGCTGACAACCATGGTCGTGTGTTTTGCACTGACGATCTCCGTTGCCGTGTCTATCGGCCTGGCGTC
CGTGCTCGGCATCCAGGTTTCGAACTCCAACATGCTGATCTCGGTGAAGGAGATGTTCAATGCGATCAACAAGTTTCCGC
TCGCAGCGATCCCGTTTTTCATCCTGGCCGGAAATTTGATGGAAACAGGCGGCATTTCACGCCGACTCGTCGAGTTTGCG
AAGAGCATTGTCGGCGGCGTTCAGGGCGGCCTGCCGATGACCTGCGTGTTGACCTGCATGATTTTTGCCGCCGTGTCGGG
TTCATCGGTTGCCACCACATTTGCCGTCGGTGCCATCCTGATTCCCGCCCTGATCAAGCACGGCTATCCGACCAGTTATG
CGGCTGCCCTGCAGGCCACCAGCGCCGAATTGGGCGTGATCATTCCGCCGTCGATTCCGATGATTCTGTATGGCGTCAGC
GCCGAGGTATCCATCGGCGAACTGTTCATCGCCGGCGTCGGCCCCGGCATCTTTATCAGCCTCGCGCTGATGGCCTTTGT
CTATGTGTATTGCAAGATCAAGGGCTGGGGGAAAAATGACGGCGATGGCCGGCTCAGTTTTGGCAAGGCCACCTGGCAGG
CCGGCTGGGCACTGCTGATGCCCGTCATCATTCTTGGCGGCATTTACGGCGGCATCTTCACGCCCACCGAAGCCGCGGCG
GTAGCGGTTTTTTATGCCCTGATTGTGGGCATGGTGATTTATCGCGAAATCAATCTGCCGGCTCTCATACTTGTCTTGCG
TAAATCCGTCCTTTCCAGCGCGGTGATCATGTTCATCATCGCCAACGCAGGACTTTTTGCGTTTCTGATCACCCGGGCGG
GCGTACCGGATGCGATTGGCCGCTGGCTGGAAGCCGTTCTGCAATCGCCGGCGCTGTTCCTGCTGGGCGTCAACACCGCG
CTGTTCATCATTGGCATGTTCATCGAAACCAGCGCAGCCATCATTGTGCTGGCGCCCATCCTGGCGCCCGTGGCCATGCA
TTTCGGCATAGATCCGGTGCATTTCGGCATGGTCATGGTGGTCAACCTGGCGCTGGGCATGATCACGCCACCCTTCGGCG
TCAATCTGTTTGCGGCCTGTACGGTGGCGCGTATTTCACTGGACCGCATCGTCGTGCACCTGCTTCCTTTCGTGCTGGTC
ATCCTGGCCTGCCTGATGGTGATCACCTATTTCCCGGCGCTGTCGCTCACGCTGCGCGATCTGGTGTACTCCAAGTAG

Upstream 100 bases:

>100_bases
GCAACATGATCCATAAATTTTCTACAGGCGTCGCGGCAAAGCCCCGCGCGAGCCGGCCAATGCCGGCTTCTTGCCCCAAC
TTTTTTCAGGAGACTGCACA

Downstream 100 bases:

>100_bases
GAAGGCCCGCACCTTGGGCTACACTTGAGAGGTCAGGAGAGAGTTTTCATCGCGAAAACCGCCGAAGGCGCACGAACACC
ATGAGGGCACCCCTCGTGGT

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTAAMLTTMVVCFALTISVAVSIGLASVLGIQVSNSNMLISVKEMFNAINKFPLAAIPFFILAGNLMETGGISRRLVEFA
KSIVGGVQGGLPMTCVLTCMIFAAVSGSSVATTFAVGAILIPALIKHGYPTSYAAALQATSAELGVIIPPSIPMILYGVS
AEVSIGELFIAGVGPGIFISLALMAFVYVYCKIKGWGKNDGDGRLSFGKATWQAGWALLMPVIILGGIYGGIFTPTEAAA
VAVFYALIVGMVIYREINLPALILVLRKSVLSSAVIMFIIANAGLFAFLITRAGVPDAIGRWLEAVLQSPALFLLGVNTA
LFIIGMFIETSAAIIVLAPILAPVAMHFGIDPVHFGMVMVVNLALGMITPPFGVNLFAACTVARISLDRIVVHLLPFVLV
ILACLMVITYFPALSLTLRDLVYSK

Sequences:

>Translated_425_residues
MTAAMLTTMVVCFALTISVAVSIGLASVLGIQVSNSNMLISVKEMFNAINKFPLAAIPFFILAGNLMETGGISRRLVEFA
KSIVGGVQGGLPMTCVLTCMIFAAVSGSSVATTFAVGAILIPALIKHGYPTSYAAALQATSAELGVIIPPSIPMILYGVS
AEVSIGELFIAGVGPGIFISLALMAFVYVYCKIKGWGKNDGDGRLSFGKATWQAGWALLMPVIILGGIYGGIFTPTEAAA
VAVFYALIVGMVIYREINLPALILVLRKSVLSSAVIMFIIANAGLFAFLITRAGVPDAIGRWLEAVLQSPALFLLGVNTA
LFIIGMFIETSAAIIVLAPILAPVAMHFGIDPVHFGMVMVVNLALGMITPPFGVNLFAACTVARISLDRIVVHLLPFVLV
ILACLMVITYFPALSLTLRDLVYSK
>Mature_424_residues
TAAMLTTMVVCFALTISVAVSIGLASVLGIQVSNSNMLISVKEMFNAINKFPLAAIPFFILAGNLMETGGISRRLVEFAK
SIVGGVQGGLPMTCVLTCMIFAAVSGSSVATTFAVGAILIPALIKHGYPTSYAAALQATSAELGVIIPPSIPMILYGVSA
EVSIGELFIAGVGPGIFISLALMAFVYVYCKIKGWGKNDGDGRLSFGKATWQAGWALLMPVIILGGIYGGIFTPTEAAAV
AVFYALIVGMVIYREINLPALILVLRKSVLSSAVIMFIIANAGLFAFLITRAGVPDAIGRWLEAVLQSPALFLLGVNTAL
FIIGMFIETSAAIIVLAPILAPVAMHFGIDPVHFGMVMVVNLALGMITPPFGVNLFAACTVARISLDRIVVHLLPFVLVI
LACLMVITYFPALSLTLRDLVYSK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=386, Percent_Identity=39.6373056994819, Blast_Score=218, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44700; Mature: 44569

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAMLTTMVVCFALTISVAVSIGLASVLGIQVSNSNMLISVKEMFNAINKFPLAAIPFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEHHHHHHHHHCCCHHHHHHH
ILAGNLMETGGISRRLVEFAKSIVGGVQGGLPMTCVLTCMIFAAVSGSSVATTFAVGAIL
HHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IPALIKHGYPTSYAAALQATSAELGVIIPPSIPMILYGVSAEVSIGELFIAGVGPGIFIS
HHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCHHHEEEECCCHHHHHH
LALMAFVYVYCKIKGWGKNDGDGRLSFGKATWQAGWALLMPVIILGGIYGGIFTPTEAAA
HHHHHHHHHHHEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VAVFYALIVGMVIYREINLPALILVLRKSVLSSAVIMFIIANAGLFAFLITRAGVPDAIG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RWLEAVLQSPALFLLGVNTALFIIGMFIETSAAIIVLAPILAPVAMHFGIDPVHFGMVMV
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VNLALGMITPPFGVNLFAACTVARISLDRIVVHLLPFVLVILACLMVITYFPALSLTLRD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVYSK
HHCCC
>Mature Secondary Structure 
TAAMLTTMVVCFALTISVAVSIGLASVLGIQVSNSNMLISVKEMFNAINKFPLAAIPFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEHHHHHHHHHCCCHHHHHHH
ILAGNLMETGGISRRLVEFAKSIVGGVQGGLPMTCVLTCMIFAAVSGSSVATTFAVGAIL
HHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IPALIKHGYPTSYAAALQATSAELGVIIPPSIPMILYGVSAEVSIGELFIAGVGPGIFIS
HHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCHHHEEEECCCHHHHHH
LALMAFVYVYCKIKGWGKNDGDGRLSFGKATWQAGWALLMPVIILGGIYGGIFTPTEAAA
HHHHHHHHHHHEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VAVFYALIVGMVIYREINLPALILVLRKSVLSSAVIMFIIANAGLFAFLITRAGVPDAIG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RWLEAVLQSPALFLLGVNTALFIIGMFIETSAAIIVLAPILAPVAMHFGIDPVHFGMVMV
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VNLALGMITPPFGVNLFAACTVARISLDRIVVHLLPFVLVILACLMVITYFPALSLTLRD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVYSK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]