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The map label for this gene is pheA [H]

Identifier: 91787674

GI number: 91787674

Start: 1853603

End: 1854685

Strand: Reverse

Name: pheA [H]

Synonym: Bpro_1792

Alternate gene names: 91787674

Gene position: 1854685-1853603 (Counterclockwise)

Preceding gene: 91787675

Following gene: 91787673

Centisome position: 35.67

GC content: 63.34

Gene sequence:

>1083_bases
ATGACTGCCAACCTCGCCGATTTGCGCGTCCAGATTGACGCCATAGACAAGGAATTGCTGGCACTCCTGAACCGCCGCGC
GCAGGTCGCCGAGCAGGTGGGAGATGTCAAAAAACTCGAAGGCACGCCCTTTTTCCGGCCCGACCGGGTTGCCCAGGTCA
TTGAGCAGATCCAGCAAGCCAACACCGGTCCGCTCAAGAACGAACATGTTGCAGCCGTCTGGCGCGAAATCATGTCGGCC
TGCCTGGCCCTCGAATCGCCGGTGCGTGTGGCCTACCTGGGGCCTGCCGGCACGTTCAGCGAACAGGCGGCCCTTCAATT
TTTTGGCGCCAGCATTGAACATGTGCCCTGCATCAGCATTGATGAAGTGTTTCGTGCCACGGCGGCGGGCAGTGCCGGTT
ATGGCGTGGTGCCGGTTGAGAACTCCACCGAAGGCGTGGTGTCGCGCTCGCTTGACCTCTTCCTGAACTCGCCGCTGCAC
ATCGTCGGCGAGATCAGCCTGATGGTGCGGCACAACCTGCTGCGGTTGTCTGACTCCCTGGACGACATCGAGGCCGTGTA
TGCACATCCTCAGGCCCTGGCACAGTGCCAGGGATGGCTGACCACCCACCTGCCCAATGCGGAACGCCGGGCCGCGTCGA
GCAACGCAGAAGGTGCACGCCTGGCCTCGACCAATCCGGCGTGGGCCGGCATCGCCAGCGATCGGGCGGCAGCGCAATTC
GGCCTGCACACGGCAGCCCACGCCATCCAGGACGACGCCTTTAACCGCACCCGTTTTGCCGTGGTCTGCCTCCCGCAGAC
GCTGCCCTCGCCACCCGCCTCGGGCAAGGACTGCGTGAGCCTGGTGGTGTCCGTGCCCAATCGCCCGGGCGCCGTGCACG
ACATCCTGGTGCCGCTGAAAACCCACGGGGTTTCGATGACCCGCTTCGAGTCACGTCCGGCACGATCGGGCCAGTGGGAA
TACTATTTCTATATTGACCTGCAAGGCCACCCGTCCCAGCCCCACGTCAAGGCAGCGCTGGCTGATTTGCAGCAACTGTG
CGCGTTTTACAAGGTTCTCGGCACCTACCCCGTCAGCGATTGA

Upstream 100 bases:

>100_bases
AACAAAAACACGCCTAGGACGACATGCCTCCACGCTCCATTTGTTCGCAGCCCCTTGACGGGGCATCCAGTGCCGTTCAG
ACGGCCGGGCGGGCACCGAT

Downstream 100 bases:

>100_bases
GGCGCAAGCAAGAGCTCCATGCAAGAATTACAAAAATTTCCGGTACCGCTTCATGTTTGAACAGTTAGGTCTCATCGGAT
GCGGCCTCATGGGCGGTTCT

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MTANLADLRVQIDAIDKELLALLNRRAQVAEQVGDVKKLEGTPFFRPDRVAQVIEQIQQANTGPLKNEHVAAVWREIMSA
CLALESPVRVAYLGPAGTFSEQAALQFFGASIEHVPCISIDEVFRATAAGSAGYGVVPVENSTEGVVSRSLDLFLNSPLH
IVGEISLMVRHNLLRLSDSLDDIEAVYAHPQALAQCQGWLTTHLPNAERRAASSNAEGARLASTNPAWAGIASDRAAAQF
GLHTAAHAIQDDAFNRTRFAVVCLPQTLPSPPASGKDCVSLVVSVPNRPGAVHDILVPLKTHGVSMTRFESRPARSGQWE
YYFYIDLQGHPSQPHVKAALADLQQLCAFYKVLGTYPVSD

Sequences:

>Translated_360_residues
MTANLADLRVQIDAIDKELLALLNRRAQVAEQVGDVKKLEGTPFFRPDRVAQVIEQIQQANTGPLKNEHVAAVWREIMSA
CLALESPVRVAYLGPAGTFSEQAALQFFGASIEHVPCISIDEVFRATAAGSAGYGVVPVENSTEGVVSRSLDLFLNSPLH
IVGEISLMVRHNLLRLSDSLDDIEAVYAHPQALAQCQGWLTTHLPNAERRAASSNAEGARLASTNPAWAGIASDRAAAQF
GLHTAAHAIQDDAFNRTRFAVVCLPQTLPSPPASGKDCVSLVVSVPNRPGAVHDILVPLKTHGVSMTRFESRPARSGQWE
YYFYIDLQGHPSQPHVKAALADLQQLCAFYKVLGTYPVSD
>Mature_359_residues
TANLADLRVQIDAIDKELLALLNRRAQVAEQVGDVKKLEGTPFFRPDRVAQVIEQIQQANTGPLKNEHVAAVWREIMSAC
LALESPVRVAYLGPAGTFSEQAALQFFGASIEHVPCISIDEVFRATAAGSAGYGVVPVENSTEGVVSRSLDLFLNSPLHI
VGEISLMVRHNLLRLSDSLDDIEAVYAHPQALAQCQGWLTTHLPNAERRAASSNAEGARLASTNPAWAGIASDRAAAQFG
LHTAAHAIQDDAFNRTRFAVVCLPQTLPSPPASGKDCVSLVVSVPNRPGAVHDILVPLKTHGVSMTRFESRPARSGQWEY
YFYIDLQGHPSQPHVKAALADLQQLCAFYKVLGTYPVSD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=372, Percent_Identity=29.5698924731183, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324013, Length=321, Percent_Identity=28.3489096573209, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 38946; Mature: 38814

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANLADLRVQIDAIDKELLALLNRRAQVAEQVGDVKKLEGTPFFRPDRVAQVIEQIQQA
CCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCC
NTGPLKNEHVAAVWREIMSACLALESPVRVAYLGPAGTFSEQAALQFFGASIEHVPCISI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCH
DEVFRATAAGSAGYGVVPVENSTEGVVSRSLDLFLNSPLHIVGEISLMVRHNLLRLSDSL
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH
DDIEAVYAHPQALAQCQGWLTTHLPNAERRAASSNAEGARLASTNPAWAGIASDRAAAQF
HHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEECCCCCCCCCCCCCHHHHHH
GLHTAAHAIQDDAFNRTRFAVVCLPQTLPSPPASGKDCVSLVVSVPNRPGAVHDILVPLK
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEEEHH
THGVSMTRFESRPARSGQWEYYFYIDLQGHPSQPHVKAALADLQQLCAFYKVLGTYPVSD
HCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TANLADLRVQIDAIDKELLALLNRRAQVAEQVGDVKKLEGTPFFRPDRVAQVIEQIQQA
CCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCC
NTGPLKNEHVAAVWREIMSACLALESPVRVAYLGPAGTFSEQAALQFFGASIEHVPCISI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCH
DEVFRATAAGSAGYGVVPVENSTEGVVSRSLDLFLNSPLHIVGEISLMVRHNLLRLSDSL
HHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCH
DDIEAVYAHPQALAQCQGWLTTHLPNAERRAASSNAEGARLASTNPAWAGIASDRAAAQF
HHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEECCCCCCCCCCCCCHHHHHH
GLHTAAHAIQDDAFNRTRFAVVCLPQTLPSPPASGKDCVSLVVSVPNRPGAVHDILVPLK
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEEEHH
THGVSMTRFESRPARSGQWEYYFYIDLQGHPSQPHVKAALADLQQLCAFYKVLGTYPVSD
HCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1919506; 10368439 [H]