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The map label for this gene is serC

Identifier: 91787675

GI number: 91787675

Start: 1854769

End: 1855875

Strand: Reverse

Name: serC

Synonym: Bpro_1793

Alternate gene names: 91787675

Gene position: 1855875-1854769 (Counterclockwise)

Preceding gene: 91787676

Following gene: 91787674

Centisome position: 35.69

GC content: 59.71

Gene sequence:

>1107_bases
ATGACCCGACCCTTCAATTTTTCCGCCGGCCCCGCGAATTTGCCTGAAGAGGTTTTGCAGCAGGCCGCCGCCGAAATGCT
GGACTGGCACGGCAGCGGCATGAGCGTCATGGAGATGAGCCACCGCGGCAAGGAGTTCATTTCCATTTACGAAAATGCGG
AAGCCGATTTCCGTGAGTTGATGGCCATTCCGCCGAACTTCAAAATCCTGTTCATGCAGGGAGGCGGCCTGGCGGAAAAC
GCCATCGTCCCGCTGAACCTGTCACGCGGTGCCTCGGCAGATTTCGTCGTGACCGGCAGCTGGAGCGACAAGTCCCAGAA
AGAAGCCCGTAAATACTGCGACGTGCAGATTGCCGCCACGAATGCAGGCAGCGACCATACCCAGTTGCCGCCGCCTGCGA
GCTGGAATTTGCGGCGCGACGCCAGCTATGTGCATGTTTGCACCAACGAGACCATCCACGGCGTGGAATTTCAGGAGCTG
CCCGATATCAAGACCCTGGGAAGTGATGCGCCGCTGGTCATCGACTTTTCATCCCATGTGGCCTCGCGGCCGGTGGACTG
GTCGAGGGTCGGGCTGGCTTTCGGCGGAGCGCAGAAAAACCTCGGGCCCGCCGGCGTGACGCTGGTGGTCGTCCGCGAAG
ATTTGATGGGACACGCCCTGCCGGCGTGCCCAAGCGCCTTTGACTACAAGACGGTGGCGGACAACCACTCGATGTACAAC
ACGCCGCCGACCTATGCGATTTATATTGCAGGCCTGACTTTTCAATGGCTCAAACGCCAGAAAGAAGGCGACGTGACGGG
CATTGCCGCCATGGAAAAGCGCAACCTTGCCAAGGCGCAACTGCTTTACGACGCCATCGACCGTTCCCAGCTGTACTTCA
ATCGCGTCGGCAGCGAGTGTCGCTCGCGCATGAATGTGCCATTTTTGTTGCGGGATGAGTCGCGCAACGAGGCTTTCCTG
GCCGGCGCCAAAGCCCACAGCCTGCTGCAACTGAAGGGCCACAAGTCCGTCGGCGGCATGCGTGCCAGCATTTACAACGC
CATGCCGCTGGCCGGTATCGAGGCGCTGATCGGCTACATGCGAGAATTCGAACAAAAACACGCCTAG

Upstream 100 bases:

>100_bases
CGCGTCAAGCAGTTTGATGATGCCGCACTGAAAATTGTCGGCCCCGCACCTGCGGCACCAGGGGCGAGCAAGCCACCCGC
CAAAAAATAACCCGATCCTA

Downstream 100 bases:

>100_bases
GACGACATGCCTCCACGCTCCATTTGTTCGCAGCCCCTTGACGGGGCATCCAGTGCCGTTCAGACGGCCGGGCGGGCACC
GATATGACTGCCAACCTCGC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTRPFNFSAGPANLPEEVLQQAAAEMLDWHGSGMSVMEMSHRGKEFISIYENAEADFRELMAIPPNFKILFMQGGGLAEN
AIVPLNLSRGASADFVVTGSWSDKSQKEARKYCDVQIAATNAGSDHTQLPPPASWNLRRDASYVHVCTNETIHGVEFQEL
PDIKTLGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGVTLVVVREDLMGHALPACPSAFDYKTVADNHSMYN
TPPTYAIYIAGLTFQWLKRQKEGDVTGIAAMEKRNLAKAQLLYDAIDRSQLYFNRVGSECRSRMNVPFLLRDESRNEAFL
AGAKAHSLLQLKGHKSVGGMRASIYNAMPLAGIEALIGYMREFEQKHA

Sequences:

>Translated_368_residues
MTRPFNFSAGPANLPEEVLQQAAAEMLDWHGSGMSVMEMSHRGKEFISIYENAEADFRELMAIPPNFKILFMQGGGLAEN
AIVPLNLSRGASADFVVTGSWSDKSQKEARKYCDVQIAATNAGSDHTQLPPPASWNLRRDASYVHVCTNETIHGVEFQEL
PDIKTLGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGVTLVVVREDLMGHALPACPSAFDYKTVADNHSMYN
TPPTYAIYIAGLTFQWLKRQKEGDVTGIAAMEKRNLAKAQLLYDAIDRSQLYFNRVGSECRSRMNVPFLLRDESRNEAFL
AGAKAHSLLQLKGHKSVGGMRASIYNAMPLAGIEALIGYMREFEQKHA
>Mature_367_residues
TRPFNFSAGPANLPEEVLQQAAAEMLDWHGSGMSVMEMSHRGKEFISIYENAEADFRELMAIPPNFKILFMQGGGLAENA
IVPLNLSRGASADFVVTGSWSDKSQKEARKYCDVQIAATNAGSDHTQLPPPASWNLRRDASYVHVCTNETIHGVEFQELP
DIKTLGSDAPLVIDFSSHVASRPVDWSRVGLAFGGAQKNLGPAGVTLVVVREDLMGHALPACPSAFDYKTVADNHSMYNT
PPTYAIYIAGLTFQWLKRQKEGDVTGIAAMEKRNLAKAQLLYDAIDRSQLYFNRVGSECRSRMNVPFLLRDESRNEAFLA
GAKAHSLLQLKGHKSVGGMRASIYNAMPLAGIEALIGYMREFEQKHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=370, Percent_Identity=47.2972972972973, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=43.2876712328767, Blast_Score=308, Evalue=4e-84,
Organism=Escherichia coli, GI1787136, Length=369, Percent_Identity=51.4905149051491, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17506897, Length=372, Percent_Identity=43.2795698924731, Blast_Score=298, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6324758, Length=394, Percent_Identity=35.7868020304569, Blast_Score=259, Evalue=5e-70,
Organism=Drosophila melanogaster, GI21356589, Length=369, Percent_Identity=45.2574525745258, Blast_Score=329, Evalue=2e-90,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_POLSJ (Q12CL3)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_548627.1
- ProteinModelPortal:   Q12CL3
- SMR:   Q12CL3
- STRING:   Q12CL3
- GeneID:   4015578
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1793
- NMPDR:   fig|296591.1.peg.2813
- eggNOG:   COG1932
- HOGENOM:   HBG289982
- OMA:   TFAWYLA
- PhylomeDB:   Q12CL3
- ProtClustDB:   PRK05355
- BioCyc:   PSP296591:BPRO_1793-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 40454; Mature: 40323

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 42-42 BINDING 101-101 BINDING 151-151 BINDING 175-175 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPFNFSAGPANLPEEVLQQAAAEMLDWHGSGMSVMEMSHRGKEFISIYENAEADFREL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHH
MAIPPNFKILFMQGGGLAENAIVPLNLSRGASADFVVTGSWSDKSQKEARKYCDVQIAAT
HCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEE
NAGSDHTQLPPPASWNLRRDASYVHVCTNETIHGVEFQELPDIKTLGSDAPLVIDFSSHV
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHCCCHHHCCCCCCEEEEECHHH
ASRPVDWSRVGLAFGGAQKNLGPAGVTLVVVREDLMGHALPACPSAFDYKTVADNHSMYN
HCCCCCHHHHEEEECCCCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCCEEECCCCCCCC
TPPTYAIYIAGLTFQWLKRQKEGDVTGIAAMEKRNLAKAQLLYDAIDRSQLYFNRVGSEC
CCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRMNVPFLLRDESRNEAFLAGAKAHSLLQLKGHKSVGGMRASIYNAMPLAGIEALIGYM
HHHCCCCEEEECCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHH
REFEQKHA
HHHHHHCC
>Mature Secondary Structure 
TRPFNFSAGPANLPEEVLQQAAAEMLDWHGSGMSVMEMSHRGKEFISIYENAEADFREL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHH
MAIPPNFKILFMQGGGLAENAIVPLNLSRGASADFVVTGSWSDKSQKEARKYCDVQIAAT
HCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEE
NAGSDHTQLPPPASWNLRRDASYVHVCTNETIHGVEFQELPDIKTLGSDAPLVIDFSSHV
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHCCCHHHCCCCCCEEEEECHHH
ASRPVDWSRVGLAFGGAQKNLGPAGVTLVVVREDLMGHALPACPSAFDYKTVADNHSMYN
HCCCCCHHHHEEEECCCCCCCCCCCEEEEEEECHHHHCCCCCCCCCCCCEEECCCCCCCC
TPPTYAIYIAGLTFQWLKRQKEGDVTGIAAMEKRNLAKAQLLYDAIDRSQLYFNRVGSEC
CCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSRMNVPFLLRDESRNEAFLAGAKAHSLLQLKGHKSVGGMRASIYNAMPLAGIEALIGYM
HHHCCCCEEEECCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHH
REFEQKHA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA