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The map label for this gene is prmA

Identifier: 91786999

GI number: 91786999

Start: 1134559

End: 1135455

Strand: Direct

Name: prmA

Synonym: Bpro_1101

Alternate gene names: 91786999

Gene position: 1134559-1135455 (Clockwise)

Preceding gene: 91786998

Following gene: 91787000

Centisome position: 21.82

GC content: 63.55

Gene sequence:

>897_bases
ATGAGCCTGTTCGAACTGATTCTGCTGGCGCCCGTTGATGAGATAGAGACGCTCAGCGAGGCGCTGGATGCGCTGGATGC
GCTCAGTGTGTCGGTGGAAGACGCGGACGCCCAGACACCTGCCGAGCAGGCGCTCTTTGGCGAGCCCGGCATGCCACCAC
CGAAGGCCGGCTGGGAGCGCTCGCGCGTGGTGTCGCTGTTTGCCTCCGAGGCCCTGGCGCGGGACGCCGCCTCCGTCCTT
ACTGCCCAGGATTTTTTTGCGGGCTGCCAGCTGGTGGCGATTCAGGCCGTGCCCGAGCAGGATTGGGTCCGGCTCACGCA
GTCGCAGTTCACGCCAGTAGAAATTACGCCTGAATTCTGGATCGTGCCGACCTGGCACGAACCGCCTGAACAGGCAAAGC
AGCTCATCCGTCTGGATCCGGGCCTGGCGTTTGGCACGGGCACCCACCCCACCACCCGCATGTGCCTGCGCTGGATTGCC
GGCCAGGGCGCGGCGAACAAGCCATTGGCCCGTGTACTCGACTATGGCTGTGGCTCGGGCATTCTGGCTATTGGCGCTGC
CAAGTTTGGGGCGGTCGATATTGATGCCGTCGATATTGACGAAGCCGCTGTCGAGTCCACACGCGCCAACGCCGAGGCCA
ACCATGTCACCCTGAATGCCGGCTTGCCTGACAAGGCGGTGGGTGCCTACCAGACCGTGCTTGCGAATATTCTGGCGACG
CCGCTGAAAGTGCTGGCGCCGCTGCTGTGCTCACATGTTCAAAAGGGCGGGAGTCTGGTGCTCGCCGGCATTCTGGAGCG
CCAGGCCGACGAACTTAAGGCGGCCTATCAGCCTTATTGCCAGCTCCAGGTGCTCGACCAGGAAGAGGGCTGGATCCTGA
TGGGCGCGCGGTTTTAA

Upstream 100 bases:

>100_bases
GTGTGACCTTGCGCCGCGCCGGGCCGCCCCAGGCAAGCCCAGCCCCCTCGGGGGGCAGAGAGCTACACGGAGTGAGCGAA
CGTGGGGGCAAAAAATCACC

Downstream 100 bases:

>100_bases
GCCCCGTCAATCAGATGCCGTTCGGCCGGCCTGCCGGCAACGACCCCCTACAATACGGCGCTAGATGAGCCTGATTACCC
GCTGCCCCGCGTGCGGCACG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWERSRVVSLFASEALARDAASVL
TAQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFWIVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIA
GQGAANKPLARVLDYGCGSGILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILAT
PLKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF

Sequences:

>Translated_298_residues
MSLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWERSRVVSLFASEALARDAASVL
TAQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFWIVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIA
GQGAANKPLARVLDYGCGSGILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILAT
PLKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF
>Mature_297_residues
SLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWERSRVVSLFASEALARDAASVLT
AQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFWIVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIAG
QGAANKPLARVLDYGCGSGILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILATP
LKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=286, Percent_Identity=36.7132867132867, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_POLSJ (Q12EI9)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547951.1
- ProteinModelPortal:   Q12EI9
- SMR:   Q12EI9
- STRING:   Q12EI9
- GeneID:   4011935
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1101
- NMPDR:   fig|296591.1.peg.3303
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- PhylomeDB:   Q12EI9
- ProtClustDB:   PRK00517
- BioCyc:   PSP296591:BPRO_1101-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31867; Mature: 31735

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWER
CCHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCH
SRVVSLFASEALARDAASVLTAQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCEEECCCEE
IVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIAGQGAANKPLARVLDYGCGSG
EEECCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCC
ILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILAT
EEEEECHHCCCEEECEECCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
PLKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCC
>Mature Secondary Structure 
SLFELILLAPVDEIETLSEALDALDALSVSVEDADAQTPAEQALFGEPGMPPPKAGWER
CHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCH
SRVVSLFASEALARDAASVLTAQDFFAGCQLVAIQAVPEQDWVRLTQSQFTPVEITPEFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCEEECCCEE
IVPTWHEPPEQAKQLIRLDPGLAFGTGTHPTTRMCLRWIAGQGAANKPLARVLDYGCGSG
EEECCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCC
ILAIGAAKFGAVDIDAVDIDEAAVESTRANAEANHVTLNAGLPDKAVGAYQTVLANILAT
EEEEECHHCCCEEECEECCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
PLKVLAPLLCSHVQKGGSLVLAGILERQADELKAAYQPYCQLQVLDQEEGWILMGARF
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA