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The map label for this gene is ybhO [H]

Identifier: 91786770

GI number: 91786770

Start: 891664

End: 892908

Strand: Direct

Name: ybhO [H]

Synonym: Bpro_0868

Alternate gene names: 91786770

Gene position: 891664-892908 (Clockwise)

Preceding gene: 91786769

Following gene: 91786771

Centisome position: 17.15

GC content: 65.3

Gene sequence:

>1245_bases
ATGTCCCCACCCCACAAGTCCGAAGCCGTGCAATTGCTCGAGGGCGCCCAGGCCTTGTTTCCGGCCCTCATCGAGGCCTT
TGATGCCGCGGTCAACTGGATACAGCTGGAAACCTATATTTTTGATGTTCACGGAGTCGCAGCGGAGGTGGCCGAGGCGC
TGGCGCGGGCAGCGGGGCGCGGCGTGACGGTGCAGGTGCTGGTCGATGGCATCGGCACCGGTCCTTTGCCGGCCGAGTGG
CAAAAAAAGTTCAGCGAAACGGGCGTGCAGTGGTGCGTCTACTCACCGCTGGGTACCGGTTTCGGCGGGTTGGGCGGCTT
GGGCATGCTGCTGCCAGACCGCTGGCGCAGGCTGCACCGCAAGCTGTGCGTGGTAGACCAGCGCGTGGTTTTTTGTGGCG
GCATCAATGTGCTGGATGACTTCTACGATCCGAACCATGGGGAGCTCCAGTCCCCGCGCCTGGATTTCGCCGTGGCTGTG
ACCGGGCCGCTGGCCGCCGATGCTGCCGACGCCGCCGCCCTGCTGTGGTGGCGCGTTCAGGCCGGCTACAGCGCACGGCA
AAGGCATTTGAGCGCGGCGTGGGAAAAGTTCAAGGCGGCCGGTTACGGCGGCCGCACCGGCAACGGGATGCTCACCGGCC
GGCCACATTTCAGGCTTGTCGGTGCGCCGGGCGCGCGGGCCGCGCTGATCTTGCGCGACAACCTGCGCAACCGCAGCAGC
ATCGAGCGTGCTTACCGCAAGGCGATTGGCCAGGCGCGCCAGGAAATCATCATTGCCAACGCTTATTTCCTGCCCGGCGG
CAAACTGCGCCGCGCCCTCATCAATGCGGCCAGACGCGGTGTGAGCGTGACCCTGCTGCTGCAGGGACGCTACGAATACT
TCATGCAATACCATGCGGCGCGGCCGGTGTACGGCGCCCTGTTGGCGGCAGGGGTGGAAATCCATGAATACGAGGCCAGT
TTTCTGCATGCCAAGGTGGCCGTCGTGGACGGACGTTGGGCCACGGTGGGCTCGTCCAACCTGGATCCGCTCAGTTTGCT
GCTGGCCCGGGAGGCCAATGTGGTGGTGGAGAACAAGGCGTTTGCCGAAGCGTTGAGAGACCGCCTGTGCGTGGCCATGA
CCAGCTACGGCCGGCGCATCGACCCCGCCGTCTACAGCCAGCGGCCGCTGGGCCAGCGTCTGCGGGGCTGGATGGCCTAT
GCCCTGATGCGACTGGCCTTGCTGATAACCGGACAGCGTTACTGA

Upstream 100 bases:

>100_bases
GCAGTCGGTTTAAATGGGCTGACAAGTCCGTCCTCATGACACCTGACACCTGACACCTGAAACCCACCAGCCCTGCCCCT
CACACGAAATTCCCCGGCCC

Downstream 100 bases:

>100_bases
GCCCATCGCCCCGGCACTGGCGGGGGAGCCGTGGCAGCCCCTATTTTGCTATCAAATATATAGCTTCATGCGCTTGTGTC
CTGTGGGCTGGGAGCTTAAA

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSPPHKSEAVQLLEGAQALFPALIEAFDAAVNWIQLETYIFDVHGVAAEVAEALARAAGRGVTVQVLVDGIGTGPLPAEW
QKKFSETGVQWCVYSPLGTGFGGLGGLGMLLPDRWRRLHRKLCVVDQRVVFCGGINVLDDFYDPNHGELQSPRLDFAVAV
TGPLAADAADAAALLWWRVQAGYSARQRHLSAAWEKFKAAGYGGRTGNGMLTGRPHFRLVGAPGARAALILRDNLRNRSS
IERAYRKAIGQARQEIIIANAYFLPGGKLRRALINAARRGVSVTLLLQGRYEYFMQYHAARPVYGALLAAGVEIHEYEAS
FLHAKVAVVDGRWATVGSSNLDPLSLLLAREANVVVENKAFAEALRDRLCVAMTSYGRRIDPAVYSQRPLGQRLRGWMAY
ALMRLALLITGQRY

Sequences:

>Translated_414_residues
MSPPHKSEAVQLLEGAQALFPALIEAFDAAVNWIQLETYIFDVHGVAAEVAEALARAAGRGVTVQVLVDGIGTGPLPAEW
QKKFSETGVQWCVYSPLGTGFGGLGGLGMLLPDRWRRLHRKLCVVDQRVVFCGGINVLDDFYDPNHGELQSPRLDFAVAV
TGPLAADAADAAALLWWRVQAGYSARQRHLSAAWEKFKAAGYGGRTGNGMLTGRPHFRLVGAPGARAALILRDNLRNRSS
IERAYRKAIGQARQEIIIANAYFLPGGKLRRALINAARRGVSVTLLLQGRYEYFMQYHAARPVYGALLAAGVEIHEYEAS
FLHAKVAVVDGRWATVGSSNLDPLSLLLAREANVVVENKAFAEALRDRLCVAMTSYGRRIDPAVYSQRPLGQRLRGWMAY
ALMRLALLITGQRY
>Mature_413_residues
SPPHKSEAVQLLEGAQALFPALIEAFDAAVNWIQLETYIFDVHGVAAEVAEALARAAGRGVTVQVLVDGIGTGPLPAEWQ
KKFSETGVQWCVYSPLGTGFGGLGGLGMLLPDRWRRLHRKLCVVDQRVVFCGGINVLDDFYDPNHGELQSPRLDFAVAVT
GPLAADAADAAALLWWRVQAGYSARQRHLSAAWEKFKAAGYGGRTGNGMLTGRPHFRLVGAPGARAALILRDNLRNRSSI
ERAYRKAIGQARQEIIIANAYFLPGGKLRRALINAARRGVSVTLLLQGRYEYFMQYHAARPVYGALLAAGVEIHEYEASF
LHAKVAVVDGRWATVGSSNLDPLSLLLAREANVVVENKAFAEALRDRLCVAMTSYGRRIDPAVYSQRPLGQRLRGWMAYA
LMRLALLITGQRY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=407, Percent_Identity=34.8894348894349, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787502, Length=399, Percent_Identity=26.8170426065163, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 45322; Mature: 45191

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPHKSEAVQLLEGAQALFPALIEAFDAAVNWIQLETYIFDVHGVAAEVAEALARAAGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHCCC
GVTVQVLVDGIGTGPLPAEWQKKFSETGVQWCVYSPLGTGFGGLGGLGMLLPDRWRRLHR
CCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCHHHHHHHH
KLCVVDQRVVFCGGINVLDDFYDPNHGELQSPRLDFAVAVTGPLAADAADAAALLWWRVQ
HHHHHCCEEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
AGYSARQRHLSAAWEKFKAAGYGGRTGNGMLTGRPHFRLVGAPGARAALILRDNLRNRSS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCEEEEEECCCCCHHH
IERAYRKAIGQARQEIIIANAYFLPGGKLRRALINAARRGVSVTLLLQGRYEYFMQYHAA
HHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCC
RPVYGALLAAGVEIHEYEASFLHAKVAVVDGRWATVGSSNLDPLSLLLAREANVVVENKA
CHHHHHHHHCCCHHHHHHHHHHEEEEEEECCCEEECCCCCCCHHHHHHHCCCCEEEECHH
FAEALRDRLCVAMTSYGRRIDPAVYSQRPLGQRLRGWMAYALMRLALLITGQRY
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPPHKSEAVQLLEGAQALFPALIEAFDAAVNWIQLETYIFDVHGVAAEVAEALARAAGR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHCCC
GVTVQVLVDGIGTGPLPAEWQKKFSETGVQWCVYSPLGTGFGGLGGLGMLLPDRWRRLHR
CCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCHHHHHHHH
KLCVVDQRVVFCGGINVLDDFYDPNHGELQSPRLDFAVAVTGPLAADAADAAALLWWRVQ
HHHHHCCEEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
AGYSARQRHLSAAWEKFKAAGYGGRTGNGMLTGRPHFRLVGAPGARAALILRDNLRNRSS
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECCCCCEEEEEECCCCCHHH
IERAYRKAIGQARQEIIIANAYFLPGGKLRRALINAARRGVSVTLLLQGRYEYFMQYHAA
HHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCC
RPVYGALLAAGVEIHEYEASFLHAKVAVVDGRWATVGSSNLDPLSLLLAREANVVVENKA
CHHHHHHHHCCCHHHHHHHHHHEEEEEEECCCEEECCCCCCCHHHHHHHCCCCEEEECHH
FAEALRDRLCVAMTSYGRRIDPAVYSQRPLGQRLRGWMAYALMRLALLITGQRY
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]