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The map label for this gene is aspS [H]

Identifier: 91786768

GI number: 91786768

Start: 889054

End: 890859

Strand: Direct

Name: aspS [H]

Synonym: Bpro_0866

Alternate gene names: 91786768

Gene position: 889054-890859 (Clockwise)

Preceding gene: 91786767

Following gene: 91786769

Centisome position: 17.1

GC content: 61.68

Gene sequence:

>1806_bases
ATGGCTATCGTTTCCCAAATGCGTTCCAATTATTGCGGTCTGGTGACCGAAAGCCTCATGGGCCAGACCGTCAGCCTGTG
CGGCTGGGTCAACCGCCGGCGCGACCATGGCGGCGTGATTTTTATTGACCTGCGTGACCGCGAGGGTTACGTGCAGGTGG
TCTGCGACCCGGACCGCGCCGATATGTTCAAGACCGCTGAAGGCGTGCGCAACGAGTTCTGCGTCCAGGTCAAGGGCGTG
GTGCGCGCCCGCCCTGAGGGCACGGTCAATGACCACCTGAAAAGCGGCAAGATCGAGGTGCTGTGCCATGAGCTGACCGT
GCTCAACCCCAGTGTCACGCCGCCCTTCCAGCTCGATGACGACAACCTGTCGGAGACGACGCGCCTGACGCACCGCGTGC
TGGACCTGCGCCGCCCCTACATGCAGAAGAACCTGATGCTGCGTTACCGCGTGGCCATGGAGACGCGCAAGTTCCTCGAC
ACCCATGGTTTCATCGACATTGAAACCCCGATGCTGACCAAGAGCACGCCCGAAGGCGCGCGCGATTACCTGGTGCCCAG
CCGCGTCAACGAAGGGCAGTTTTTTGCATTGCCGCAAAGCCCACAGCTGTTCAAGCAGTTGCTGATGGTGGCCGGCTTTG
ACCGCTACTACCAGATCACCAAGTGCTTTCGTGACGAAGACCTGCGCGCCGACCGCCAGCCCGAATTCACGCAGATCGAT
ATCGAGACGTCCTTCATGGCGGAGCAGGACATCCGCGACATGTTCCAGGGCATGATCAGCAACATCTTCAAGACCGTGCT
GGATACCGACCTGGGCGAGTTCCCGGTGATGGCCTACAACGATGCCATGCACCGGTACGGCTCCGACAAGCCCGACCTGC
GGGTGAACCTCGAATTCACCGAGCTGACCGATGTCATGGCCGATGTCGATTTCAAGGTGTTCAGCACGCCGGCCACCACC
AAGGGCGGCCGCGTGGTTGCGCTGCGCGTGCCGGGTGGCTCCGAGATGAGCCGCGGCGAGATCGACGGCTACACCGAGTT
TGTCAAGATCTACGGCGCCAAGGGCCTGGCCTGGATCAAGGTCAATGATGCGGGCAAGGGCCGTGAAGGGCTGCAGAGCC
CCATCGTCAAGAACCTCCATGACGCAGCCATCGCCGAAATCCTCAAGCGCACCGGTGCCCGGAACGGTGACCTGATTTTC
TTTGGCGCCGACAAGGAAAAAGTCGTCAACGACAGCATCGGCGCCCTGCGCCTGAAGGTCGGCCACAGCGAATTCGGTAA
AAAGACCGGCCTGTTCACCGCCGGCTGGAAGCCGCTGTGGGTCGTGGACTTTCCAATGTTTGAATTTGATGAAGAAGGCC
AGCGCTGGAGCGCGGTGCACCACCCCTTCACGGCACCCAAGGACGGGCACGAAGACTGGATGGACACCGATCCCGGACGC
TGCATCTCCAAGGCCTACGACATGGTGCTCAACGGCTGGGAGCTCGGTGGGGGCTCGGTCCGTATCCACCGTGCCGATGT
GCAGAACAAGGTGTTCAATGCGCTGAAGATCGGGCCGGAAGAAGCGCAGCAGAAATTCGGCTTCCTGCTGGATGCCCTGC
AATACGGCGCTCCGCCGCACGGTGGCCTGGCCTTTGGCCTGGATCGCATCGTCACCATGATGACCGGGGCCGAGTCGATC
CGTGACGTGATTGCCTTCCCGAAAACCCAGCGGGCGCAGTGCCTGTTGACCCATGCGCCGAGCCCGGTCGATGAAAAGCA
GCTGCGCGAGCTGCATATCCGCCTGCGCAATCCGCTGCCGGTTTGA

Upstream 100 bases:

>100_bases
GTTGTTGTTCCCGCAAAGCCCCTCCCGCCGCCGACTCAACCCCTGTAAACGGCGAAAACTGCCCAAGAGCCCAAGAGGCA
TTGAAAGTTCGAGTATTTTT

Downstream 100 bases:

>100_bases
ATGTGGCCCCCACGGTCGCTCGCTTCGCGTAGCTTCCTGCCCCCCGAGGGGGCCGCTGCGCCTGCGGCCCGGCTGAGCCG
GTTCCGCGGCCCCTGCTTGA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MAIVSQMRSNYCGLVTESLMGQTVSLCGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRADMFKTAEGVRNEFCVQVKGV
VRARPEGTVNDHLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPYMQKNLMLRYRVAMETRKFLD
THGFIDIETPMLTKSTPEGARDYLVPSRVNEGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQID
IETSFMAEQDIRDMFQGMISNIFKTVLDTDLGEFPVMAYNDAMHRYGSDKPDLRVNLEFTELTDVMADVDFKVFSTPATT
KGGRVVALRVPGGSEMSRGEIDGYTEFVKIYGAKGLAWIKVNDAGKGREGLQSPIVKNLHDAAIAEILKRTGARNGDLIF
FGADKEKVVNDSIGALRLKVGHSEFGKKTGLFTAGWKPLWVVDFPMFEFDEEGQRWSAVHHPFTAPKDGHEDWMDTDPGR
CISKAYDMVLNGWELGGGSVRIHRADVQNKVFNALKIGPEEAQQKFGFLLDALQYGAPPHGGLAFGLDRIVTMMTGAESI
RDVIAFPKTQRAQCLLTHAPSPVDEKQLRELHIRLRNPLPV

Sequences:

>Translated_601_residues
MAIVSQMRSNYCGLVTESLMGQTVSLCGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRADMFKTAEGVRNEFCVQVKGV
VRARPEGTVNDHLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPYMQKNLMLRYRVAMETRKFLD
THGFIDIETPMLTKSTPEGARDYLVPSRVNEGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQID
IETSFMAEQDIRDMFQGMISNIFKTVLDTDLGEFPVMAYNDAMHRYGSDKPDLRVNLEFTELTDVMADVDFKVFSTPATT
KGGRVVALRVPGGSEMSRGEIDGYTEFVKIYGAKGLAWIKVNDAGKGREGLQSPIVKNLHDAAIAEILKRTGARNGDLIF
FGADKEKVVNDSIGALRLKVGHSEFGKKTGLFTAGWKPLWVVDFPMFEFDEEGQRWSAVHHPFTAPKDGHEDWMDTDPGR
CISKAYDMVLNGWELGGGSVRIHRADVQNKVFNALKIGPEEAQQKFGFLLDALQYGAPPHGGLAFGLDRIVTMMTGAESI
RDVIAFPKTQRAQCLLTHAPSPVDEKQLRELHIRLRNPLPV
>Mature_600_residues
AIVSQMRSNYCGLVTESLMGQTVSLCGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRADMFKTAEGVRNEFCVQVKGVV
RARPEGTVNDHLKSGKIEVLCHELTVLNPSVTPPFQLDDDNLSETTRLTHRVLDLRRPYMQKNLMLRYRVAMETRKFLDT
HGFIDIETPMLTKSTPEGARDYLVPSRVNEGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDI
ETSFMAEQDIRDMFQGMISNIFKTVLDTDLGEFPVMAYNDAMHRYGSDKPDLRVNLEFTELTDVMADVDFKVFSTPATTK
GGRVVALRVPGGSEMSRGEIDGYTEFVKIYGAKGLAWIKVNDAGKGREGLQSPIVKNLHDAAIAEILKRTGARNGDLIFF
GADKEKVVNDSIGALRLKVGHSEFGKKTGLFTAGWKPLWVVDFPMFEFDEEGQRWSAVHHPFTAPKDGHEDWMDTDPGRC
ISKAYDMVLNGWELGGGSVRIHRADVQNKVFNALKIGPEEAQQKFGFLLDALQYGAPPHGGLAFGLDRIVTMMTGAESIR
DVIAFPKTQRAQCLLTHAPSPVDEKQLRELHIRLRNPLPV

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=608, Percent_Identity=37.6644736842105, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI45439306, Length=309, Percent_Identity=28.8025889967638, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI194272210, Length=247, Percent_Identity=26.7206477732794, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI5031815, Length=247, Percent_Identity=26.7206477732794, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI4758762, Length=260, Percent_Identity=25.3846153846154, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788173, Length=590, Percent_Identity=57.9661016949153, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=314, Percent_Identity=26.4331210191083, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790571, Length=294, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566633, Length=611, Percent_Identity=34.860883797054, Blast_Score=311, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI71994340, Length=269, Percent_Identity=22.3048327137546, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=269, Percent_Identity=22.3048327137546, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=269, Percent_Identity=22.3048327137546, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551876, Length=265, Percent_Identity=25.2830188679245, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325153, Length=640, Percent_Identity=34.53125, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6323011, Length=336, Percent_Identity=27.9761904761905, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324256, Length=181, Percent_Identity=30.939226519337, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320242, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584738, Length=611, Percent_Identity=35.1882160392799, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24640849, Length=254, Percent_Identity=26.7716535433071, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640851, Length=254, Percent_Identity=26.7716535433071, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=26.8939393939394, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67748; Mature: 67617

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVSQMRSNYCGLVTESLMGQTVSLCGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCHH
DMFKTAEGVRNEFCVQVKGVVRARPEGTVNDHLKSGKIEVLCHELTVLNPSVTPPFQLDD
HHHHHHHHHHHHHEEEEEHHEECCCCCCHHHHHCCCCEEEEEEEEEEECCCCCCCEEECC
DNLSETTRLTHRVLDLRRPYMQKNLMLRYRVAMETRKFLDTHGFIDIETPMLTKSTPEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
RDYLVPSRVNEGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQID
HHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
IETSFMAEQDIRDMFQGMISNIFKTVLDTDLGEFPVMAYNDAMHRYGSDKPDLRVNLEFT
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCCEEEEEEHH
ELTDVMADVDFKVFSTPATTKGGRVVALRVPGGSEMSRGEIDGYTEFVKIYGAKGLAWIK
HHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VNDAGKGREGLQSPIVKNLHDAAIAEILKRTGARNGDLIFFGADKEKVVNDSIGALRLKV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCEEEEEE
GHSEFGKKTGLFTAGWKPLWVVDFPMFEFDEEGQRWSAVHHPFTAPKDGHEDWMDTDPGR
CCHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHH
CISKAYDMVLNGWELGGGSVRIHRADVQNKVFNALKIGPEEAQQKFGFLLDALQYGAPPH
HHHHHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRIVTMMTGAESIRDVIAFPKTQRAQCLLTHAPSPVDEKQLRELHIRLRNPLP
CCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
V
C
>Mature Secondary Structure 
AIVSQMRSNYCGLVTESLMGQTVSLCGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRA
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCHH
DMFKTAEGVRNEFCVQVKGVVRARPEGTVNDHLKSGKIEVLCHELTVLNPSVTPPFQLDD
HHHHHHHHHHHHHEEEEEHHEECCCCCCHHHHHCCCCEEEEEEEEEEECCCCCCCEEECC
DNLSETTRLTHRVLDLRRPYMQKNLMLRYRVAMETRKFLDTHGFIDIETPMLTKSTPEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
RDYLVPSRVNEGQFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQID
HHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
IETSFMAEQDIRDMFQGMISNIFKTVLDTDLGEFPVMAYNDAMHRYGSDKPDLRVNLEFT
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCCEEEEEEHH
ELTDVMADVDFKVFSTPATTKGGRVVALRVPGGSEMSRGEIDGYTEFVKIYGAKGLAWIK
HHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VNDAGKGREGLQSPIVKNLHDAAIAEILKRTGARNGDLIFFGADKEKVVNDSIGALRLKV
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCEEEEEE
GHSEFGKKTGLFTAGWKPLWVVDFPMFEFDEEGQRWSAVHHPFTAPKDGHEDWMDTDPGR
CCHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHH
CISKAYDMVLNGWELGGGSVRIHRADVQNKVFNALKIGPEEAQQKFGFLLDALQYGAPPH
HHHHHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRIVTMMTGAESIRDVIAFPKTQRAQCLLTHAPSPVDEKQLRELHIRLRNPLP
CCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA