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The map label for this gene is hisI [H]

Identifier: 91786712

GI number: 91786712

Start: 835782

End: 836171

Strand: Direct

Name: hisI [H]

Synonym: Bpro_0810

Alternate gene names: 91786712

Gene position: 835782-836171 (Clockwise)

Preceding gene: 91786711

Following gene: 91786713

Centisome position: 16.07

GC content: 59.74

Gene sequence:

>390_bases
ATGAACTGGTTAGACGAAGTCAGCTGGGATGAAAAAGGCCTGATCCCGGTCATCGCGCAGGAAGCTTCCAGCGGCGATGT
GCTCATGTTCGCCTGGATGAACCGCGAGGCACTGCAAAAGACCGCCGAGCTGGGGCAGGCGGTTTACTACAGCCGCTCGC
GCGGGCGCCTGTGGCACAAAGGTGAAGAATCGGGCCACCTCCAGACCGTGCACGAAATTCGGCTCGACTGCGACAACGAC
GTGGTTTTGCTCAAGGTGACGCAACTCGGCCACGAGCCCGGCATTGCCTGCCACACCGGCCGCCACAGCTGCTTTTTTCA
CCTCTACAAAGACGGCCAGTGGGTCGTGACCGAGCCGGTCTTGAAAGATCCCGGCAGCATCTACAAATAG

Upstream 100 bases:

>100_bases
GCGACATCTGCGGTCCGGCCAAGCCGGCCCCGCGATGTCCTGGCCTGGAGGGTTTTGTGTTGCAATCGCCTGAAGTATTC
AAATCCCCGACAATAGACCC

Downstream 100 bases:

>100_bases
CCTCAGCCTTACCGGTAACGCGCATGTCCTCCAACGACTCCCTCCAGCGCCTGGCGCAGATCATTGAAAGCCGCAAGCCG
GCCAACGGCGGCGACCCTGG

Product: phosphoribosyl-AMP cyclohydrolase

Products: NA

Alternate protein names: PRA-CH [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHKGEESGHLQTVHEIRLDCDND
VVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPVLKDPGSIYK

Sequences:

>Translated_129_residues
MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHKGEESGHLQTVHEIRLDCDND
VVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPVLKDPGSIYK
>Mature_129_residues
MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHKGEESGHLQTVHEIRLDCDND
VVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPVLKDPGSIYK

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0139

COG function: function code E; Phosphoribosyl-AMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-CH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=101, Percent_Identity=48.5148514851485, Blast_Score=98, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002496
- ProDom:   PD002610 [H]

Pfam domain/function: PF01502 PRA-CH [H]

EC number: =3.5.4.19 [H]

Molecular weight: Translated: 14707; Mature: 14707

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHK
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHEEEECCCCCCEEC
GEESGHLQTVHEIRLDCDNDVVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPV
CCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCEEEEEEEECCCEEEECCC
LKDPGSIYK
CCCCCCCCC
>Mature Secondary Structure
MNWLDEVSWDEKGLIPVIAQEASSGDVLMFAWMNREALQKTAELGQAVYYSRSRGRLWHK
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHEEEECCCCCCEEC
GEESGHLQTVHEIRLDCDNDVVLLKVTQLGHEPGIACHTGRHSCFFHLYKDGQWVVTEPV
CCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCEEEECCCCEEEEEEEECCCEEEECCC
LKDPGSIYK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA