Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 91786704

GI number: 91786704

Start: 827963

End: 829237

Strand: Direct

Name: murA [H]

Synonym: Bpro_0802

Alternate gene names: 91786704

Gene position: 827963-829237 (Clockwise)

Preceding gene: 91786703

Following gene: 91786705

Centisome position: 15.92

GC content: 64.78

Gene sequence:

>1275_bases
ATGGACAAACTACTCATCAAGGGCGGCAGATCGCTCGCCGGCACCGTCGATATCTCGGGCGCCAAGAATGCCGCCCTCCC
GGAACTGTGCGCGGCGCTGCTCACGGCCGACACTGTGACGCTGGAGAACGTGCCGCGCCTGCAGGACGTGGCCACCATGC
TCAAGCTGATCCGCAACATGGGCGTGGAAGCCGAACGCGGCACCCATGCGCCGGGAACCGTCACCCTCCATGCCGGCGCC
TTGAGCTCGCCCGAAGCGCCCTATGAATTGGTGAAGACCATGCGCGCCTCCGTGCTGGCGCTGGGCCCGCTGCTGGCGCG
CTTTGGCGAAGCCACGGTGTCGCTGCCCGGTGGCTGCGCCATTGGCTCGCGGCCGGTAGACCAGCACATCAAGGGCCTGC
AGGCCATGGGCGCCGAGATCGTGGTCGAGCACGGCTACATGATTGCCAAACTTCCTGCGGGTCAAAAGCGCCTCAAGGGT
GTCAGCATCACCACCGACATGGTGACCGTCACCGGCACGGAAAACTTCCTGATGGCCGCCAGCCTGGCCGAAGGCGAAAC
GATTCTGGAAAACGCCGCGCAGGAGCCCGAGATCGGCGACCTGGCTGACATGCTCATCAAGATGGGCGCGAAGATCGAAG
GCCACGGCACGCGCCGCATCCGCATCCAGGGCGTGGAGCGCCTGCATGGCTGTACCCACCAGGTGGTGGCCGACCGCATT
GAAACCGGCACCTTTCTGTGCGCGGTGGCCGCGGCGGGCGGCGATGTGGTGCTCCGGCATGGCCGGGCCGACCACCTCGA
TGCGGTCATCGACAAGCTGCGCGAAGCGGGCGCCACCATCACGGCCGGCGAGGGATTCATCCGCATCCAGGCGCAGGGCC
GCATGAAGGCCCAGTCCTTCCGTACCACGGAATATCCGGGTTTTCCCACCGACATGCAGGCCCAGTTCATGGCGCTCAAC
GCCATTGCACAGGGCAGCAGCACGGTCACCGAAACGATTTTTGAAAACCGCTTCATGCACGTCAACGAGATGGTGCGCCT
GGGTGCGAAGATCCAGATCGAAGGCAAGGCGGCCGTCATGGAAGGCGTTGAAAAACTTTCGGGCGCCACCGTCATGGCCA
CCGATCTGCGGGCTTCCGCCAGCCTGGTGATTGCCGGCCTGGTGGCCGAAGGCGAAACCCTGGTGGACCGGATTTACCAC
CTGGACCGCGGCTACGACCAGATGGAGGCCAAATTGCGCGGCATCGGTGCAGACATAGAACGGGTAAGGGCATGA

Upstream 100 bases:

>100_bases
GCGCCTGCAGACCGATGAAGTGCATGCGCTGTCCATGAAAACCTACACGCCCGCGGAGTGGGCGGCCAACAACGCAAACC
AAGCAGCAGACTGACAACGC

Downstream 100 bases:

>100_bases
GCCCCCACGCTTGTCGCTTCGCGTACTACGCTGCCCCCCGAGGGGGCCGCCCGCCTGCAGTCCGGCGAAGCCGGCCCTGC
GGCTTGAACTTGGCAAGGCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDKLLIKGGRSLAGTVDISGAKNAALPELCAALLTADTVTLENVPRLQDVATMLKLIRNMGVEAERGTHAPGTVTLHAGA
LSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAEIVVEHGYMIAKLPAGQKRLKG
VSITTDMVTVTGTENFLMAASLAEGETILENAAQEPEIGDLADMLIKMGAKIEGHGTRRIRIQGVERLHGCTHQVVADRI
ETGTFLCAVAAAGGDVVLRHGRADHLDAVIDKLREAGATITAGEGFIRIQAQGRMKAQSFRTTEYPGFPTDMQAQFMALN
AIAQGSSTVTETIFENRFMHVNEMVRLGAKIQIEGKAAVMEGVEKLSGATVMATDLRASASLVIAGLVAEGETLVDRIYH
LDRGYDQMEAKLRGIGADIERVRA

Sequences:

>Translated_424_residues
MDKLLIKGGRSLAGTVDISGAKNAALPELCAALLTADTVTLENVPRLQDVATMLKLIRNMGVEAERGTHAPGTVTLHAGA
LSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAEIVVEHGYMIAKLPAGQKRLKG
VSITTDMVTVTGTENFLMAASLAEGETILENAAQEPEIGDLADMLIKMGAKIEGHGTRRIRIQGVERLHGCTHQVVADRI
ETGTFLCAVAAAGGDVVLRHGRADHLDAVIDKLREAGATITAGEGFIRIQAQGRMKAQSFRTTEYPGFPTDMQAQFMALN
AIAQGSSTVTETIFENRFMHVNEMVRLGAKIQIEGKAAVMEGVEKLSGATVMATDLRASASLVIAGLVAEGETLVDRIYH
LDRGYDQMEAKLRGIGADIERVRA
>Mature_424_residues
MDKLLIKGGRSLAGTVDISGAKNAALPELCAALLTADTVTLENVPRLQDVATMLKLIRNMGVEAERGTHAPGTVTLHAGA
LSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCAIGSRPVDQHIKGLQAMGAEIVVEHGYMIAKLPAGQKRLKG
VSITTDMVTVTGTENFLMAASLAEGETILENAAQEPEIGDLADMLIKMGAKIEGHGTRRIRIQGVERLHGCTHQVVADRI
ETGTFLCAVAAAGGDVVLRHGRADHLDAVIDKLREAGATITAGEGFIRIQAQGRMKAQSFRTTEYPGFPTDMQAQFMALN
AIAQGSSTVTETIFENRFMHVNEMVRLGAKIQIEGKAAVMEGVEKLSGATVMATDLRASASLVIAGLVAEGETLVDRIYH
LDRGYDQMEAKLRGIGADIERVRA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=56.6037735849057, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44954; Mature: 44954

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLIKGGRSLAGTVDISGAKNAALPELCAALLTADTVTLENVPRLQDVATMLKLIRNM
CCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHC
GVEAERGTHAPGTVTLHAGALSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCA
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
IGSRPVDQHIKGLQAMGAEIVVEHGYMIAKLPAGQKRLKGVSITTDMVTVTGTENFLMAA
CCCCCHHHHHHHHHHCCCCEEEECCEEEEECCCCHHHHCCEEEEEEEEEEECCCCEEEEE
SLAEGETILENAAQEPEIGDLADMLIKMGAKIEGHGTRRIRIQGVERLHGCTHQVVADRI
HHCCCHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCEEEEEECHHHHHCHHHHHHHHHH
ETGTFLCAVAAAGGDVVLRHGRADHLDAVIDKLREAGATITAGEGFIRIQAQGRMKAQSF
CCCEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHC
RTTEYPGFPTDMQAQFMALNAIAQGSSTVTETIFENRFMHVNEMVRLGAKIQIEGKAAVM
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHH
EGVEKLSGATVMATDLRASASLVIAGLVAEGETLVDRIYHLDRGYDQMEAKLRGIGADIE
HHHHHHCCCEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHH
RVRA
HHCC
>Mature Secondary Structure
MDKLLIKGGRSLAGTVDISGAKNAALPELCAALLTADTVTLENVPRLQDVATMLKLIRNM
CCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHC
GVEAERGTHAPGTVTLHAGALSSPEAPYELVKTMRASVLALGPLLARFGEATVSLPGGCA
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
IGSRPVDQHIKGLQAMGAEIVVEHGYMIAKLPAGQKRLKGVSITTDMVTVTGTENFLMAA
CCCCCHHHHHHHHHHCCCCEEEECCEEEEECCCCHHHHCCEEEEEEEEEEECCCCEEEEE
SLAEGETILENAAQEPEIGDLADMLIKMGAKIEGHGTRRIRIQGVERLHGCTHQVVADRI
HHCCCHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCEEEEEECHHHHHCHHHHHHHHHH
ETGTFLCAVAAAGGDVVLRHGRADHLDAVIDKLREAGATITAGEGFIRIQAQGRMKAQSF
CCCEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHC
RTTEYPGFPTDMQAQFMALNAIAQGSSTVTETIFENRFMHVNEMVRLGAKIQIEGKAAVM
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHH
EGVEKLSGATVMATDLRASASLVIAGLVAEGETLVDRIYHLDRGYDQMEAKLRGIGADIE
HHHHHHCCCEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHH
RVRA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA