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The map label for this gene is kdsB [H]

Identifier: 89256692

GI number: 89256692

Start: 1329195

End: 1329947

Strand: Reverse

Name: kdsB [H]

Synonym: FTL_1399

Alternate gene names: 89256692

Gene position: 1329947-1329195 (Counterclockwise)

Preceding gene: 89256693

Following gene: 89256691

Centisome position: 70.15

GC content: 32.8

Gene sequence:

>753_bases
ATGGCTAATATTCATATTGTAATTCCTGCCAGGCTTAAATCAACTCGTCTACCAAATAAAATGCTGGCAGATATTGCCGG
TAAGCCAATGATTCAGAGAGTCTATGAGCAAGTGACTAAATCAAAGTTTGATAGCATAATAATAGCTACAGATTCGCAAA
AAATAAAAGATATCGCAGAGAGCTTTGGTGCAAAAGTAGTTTTGACAAGAGATGATCATCAATCAGGAACAGATAGAATA
GCAGAAGCAGTTACTAAATTAGGCTTTGCATATGAAGACATTGTTGTAAATGTCCAAGGTGATGAGCCATTGATCCCTAT
TGAAAATATCGAGCAAGCTGCGCAGTTATTGATAGACAAATCAGAAGCTGTAGTCTCGACGTTGTGTGAAAAAATCACAG
ATGTAGAAGATATTTATAATCCTAATAATGTCAAAGTAGTTTTTGATAAAAATAACTATGCTTTATATTTTAGTAGAGCA
TCTATTCCTTTTGAAAGAGGTTTTTCTGAGAAAGAGCAGATTAATATTTCAGAATTTTTTAGACATATTGGTATATATGC
ATATCGAGTAGCTTTTTTAAAACATTATGCAGAACTTACAGTTTCACCAATTGAGAAATACGAAGCTCTTGAACAGCTAA
GAGTCTTATATAATGGTTACAAAATCGCTATTGAGCAATCAGCTAAATCAACTCCTGCTGGTGTTGATACATTGCAAGAT
TTAGAAAAAGTAAGGAAATTATTTAATGTTTAA

Upstream 100 bases:

>100_bases
GTATGTAAAGCAGATAAATTGGCTTATCCAATTCGTGAAAATATACCAGTAATGTTGGTTGAAGAAGCTAAAAAAATGAC
TCTTGAAGAGGTGAAAAAAT

Downstream 100 bases:

>100_bases
ATTAGACTCTCGTTTAGCAGCCGATACTTTTGAAGTTTGTGAGCATTTGGATTGTAAAATTTTAGTAATGAATAATTCTA
TTGTACCTTGGTTTATAGTA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRI
AEAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRA
SIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQD
LEKVRKLFNV

Sequences:

>Translated_250_residues
MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRI
AEAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRA
SIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQD
LEKVRKLFNV
>Mature_249_residues
ANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRIA
EAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRAS
IPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQDL
EKVRKLFNV

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=241, Percent_Identity=47.7178423236515, Blast_Score=226, Evalue=9e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28277; Mature: 28146

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAE
CCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
SFGAKVVLTRDDHQSGTDRIAEAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDK
HHCCEEEEECCCCCCCHHHHHHHHHHHCCEEEHEEEEECCCCCCCCHHHHHHHHHHHHCC
SEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSEKEQINISEFF
HHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCEEEEEEECCCCHHHCCCHHHCCCHHHHH
RHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
LEKVRKLFNV
HHHHHHHHCC
>Mature Secondary Structure 
ANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAE
CEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHH
SFGAKVVLTRDDHQSGTDRIAEAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDK
HHCCEEEEECCCCCCCHHHHHHHHHHHCCEEEHEEEEECCCCCCCCHHHHHHHHHHHHCC
SEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSEKEQINISEFF
HHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCEEEEEEECCCCHHHCCCHHHCCCHHHHH
RHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
LEKVRKLFNV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA