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The map label for this gene is bdhA [H]

Identifier: 89256590

GI number: 89256590

Start: 1220604

End: 1221203

Strand: Direct

Name: bdhA [H]

Synonym: FTL_1281

Alternate gene names: 89256590

Gene position: 1220604-1221203 (Clockwise)

Preceding gene: 89256589

Following gene: 89256591

Centisome position: 64.38

GC content: 35.83

Gene sequence:

>600_bases
ATGGATGTTACAAATGAAGACCAAGTGAAATCCGGTGTAGATGAAACTGTCAAAAAATTTGGGCGTATTGATACTGTAAT
TAATAACGCAGGTATTCAGATAATATCACCTATAGTAGATTTTAGTATATCAGCTTGGAAAAAATTATTTGATATTCATA
TGACTGGTATATTACTTGTGACTCAAGCAGCTATGAGACATATGATTGAACTAAAAACTGGTGGTAGAATTATAGTTGTA
GGTTCTGTTCACTCAGTTCTTGCATCAAAAAATAAAGCAGCTTATGTAGCAGCTAAACACGCACAAGTTGGTTTTGTAAG
AGCTTTAGCAAAAGAAGGTGCTGAGCACAATATCTCATCTAACCTAATTGGTCCAGGTTTTGTGATGACGCCATTAGTAG
AAAAGCAAATTCCAGAGCAAGCAAAAGAGCTAAATATTTCCGAAGAAGAAGTTGTCAAAAATATTATGCTTAGTGGCACT
GTAGATGGTGAGTTCACAACGGTCCAAGATATCGCTGATACAGCCATATTCTTAGCTGGATTCAAAACCAATGCTCTAAC
AGGTCAGAAAATTTTGGTAAGTCATGGTTGGGGAATGTAA

Upstream 100 bases:

>100_bases
AGGCGCTAAAGTAGTAATCGCAGATTTAGATATTGAAAAATCACAAGCTGTAGCAAAAGATTTAGCAGATAAATATACTG
TAGAAACTTTAGCTGTATAA

Downstream 100 bases:

>100_bases
ACAAAGCTAATACTTCTGTGATATATTTATTCTCATATTAATATTATTCTAAAACTGTAGATGTCTACAAACTCAAATAT
AAGACAAAAACTAGGTCAAT

Product: D-Beta-hydroxybutyrate dehydrogenase, pseudogene

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MDVTNEDQVKSGVDETVKKFGRIDTVINNAGIQIISPIVDFSISAWKKLFDIHMTGILLVTQAAMRHMIELKTGGRIIVV
GSVHSVLASKNKAAYVAAKHAQVGFVRALAKEGAEHNISSNLIGPGFVMTPLVEKQIPEQAKELNISEEEVVKNIMLSGT
VDGEFTTVQDIADTAIFLAGFKTNALTGQKILVSHGWGM

Sequences:

>Translated_199_residues
MDVTNEDQVKSGVDETVKKFGRIDTVINNAGIQIISPIVDFSISAWKKLFDIHMTGILLVTQAAMRHMIELKTGGRIIVV
GSVHSVLASKNKAAYVAAKHAQVGFVRALAKEGAEHNISSNLIGPGFVMTPLVEKQIPEQAKELNISEEEVVKNIMLSGT
VDGEFTTVQDIADTAIFLAGFKTNALTGQKILVSHGWGM
>Mature_199_residues
MDVTNEDQVKSGVDETVKKFGRIDTVINNAGIQIISPIVDFSISAWKKLFDIHMTGILLVTQAAMRHMIELKTGGRIIVV
GSVHSVLASKNKAAYVAAKHAQVGFVRALAKEGAEHNISSNLIGPGFVMTPLVEKQIPEQAKELNISEEEVVKNIMLSGT
VDGEFTTVQDIADTAIFLAGFKTNALTGQKILVSHGWGM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=197, Percent_Identity=31.4720812182741, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=30.3030303030303, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4504505, Length=153, Percent_Identity=37.2549019607843, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI66933014, Length=199, Percent_Identity=25.1256281407035, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=139, Percent_Identity=32.3741007194245, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI15277342, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI20149619, Length=132, Percent_Identity=28.030303030303, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI32483357, Length=185, Percent_Identity=27.5675675675676, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4503301, Length=179, Percent_Identity=27.3743016759777, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI157739938, Length=140, Percent_Identity=27.8571428571429, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI31542939, Length=138, Percent_Identity=29.7101449275362, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=30.4568527918782, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082160, Length=197, Percent_Identity=28.9340101522843, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789208, Length=196, Percent_Identity=28.0612244897959, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=27.6381909547739, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI87082100, Length=196, Percent_Identity=31.1224489795918, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789057, Length=206, Percent_Identity=30.0970873786408, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=197, Percent_Identity=26.9035532994924, Blast_Score=61, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=27.6381909547739, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=28.643216080402, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=200, Percent_Identity=28.5, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=141, Percent_Identity=37.5886524822695, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=200, Percent_Identity=25.5, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=205, Percent_Identity=29.7560975609756, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=210, Percent_Identity=29.0476190476191, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=30.3664921465969, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=150, Percent_Identity=34.6666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24639444, Length=199, Percent_Identity=29.1457286432161, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859837, Length=113, Percent_Identity=34.5132743362832, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641232, Length=166, Percent_Identity=27.710843373494, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=26.7379679144385, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 21470; Mature: 21470

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTNEDQVKSGVDETVKKFGRIDTVINNAGIQIISPIVDFSISAWKKLFDIHMTGILLV
CCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAAMRHMIELKTGGRIIVVGSVHSVLASKNKAAYVAAKHAQVGFVRALAKEGAEHNISS
HHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCC
NLIGPGFVMTPLVEKQIPEQAKELNISEEEVVKNIMLSGTVDGEFTTVQDIADTAIFLAG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
FKTNALTGQKILVSHGWGM
CCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MDVTNEDQVKSGVDETVKKFGRIDTVINNAGIQIISPIVDFSISAWKKLFDIHMTGILLV
CCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQAAMRHMIELKTGGRIIVVGSVHSVLASKNKAAYVAAKHAQVGFVRALAKEGAEHNISS
HHHHHHHHHHHCCCCEEEEEECHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCC
NLIGPGFVMTPLVEKQIPEQAKELNISEEEVVKNIMLSGTVDGEFTTVQDIADTAIFLAG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
FKTNALTGQKILVSHGWGM
CCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]