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The map label for this gene is dnaQ [H]

Identifier: 89256347

GI number: 89256347

Start: 968440

End: 969156

Strand: Direct

Name: dnaQ [H]

Synonym: FTL_1003

Alternate gene names: 89256347

Gene position: 968440-969156 (Clockwise)

Preceding gene: 89256346

Following gene: 89256348

Centisome position: 51.08

GC content: 30.4

Gene sequence:

>717_bases
ATGATATATATACTATTTTTTAGAATGTCACGACAAGTTTTTATAGATACTGAGACAACTGGCTTTGATTATAAGATTGG
TAATAGAATTATTGAATTTGGTGCAGTTGAAGTTATTGATAGAAGGATAACAGGTAATAATTTACATTTTTATTGTAATC
CAAATTATAAAGTTGAAGCTGGAGCTTTAGCTATTCATGGTCTTACAAATGAATTTCTAGCAGATAAACCTCTTTTTGAG
GATAAAGTTGATGAGATGATTGAGTTTTTAAGAGGTGCTGAAGTAATCATTCATAATGCAGCTTTTGATGTGCCATTTAT
AAATTGGGAACTTAGTCTCTTAAAAAATAATAAATACGGAACATTAGAGCAAAATGTTGCTAAAATAGTAGATAGCCTTG
ATTTAGCTAGAAAAAAACATCCATTACAAAAAAATAATCTTGATGCTCTATGTAAAAGATATCAAATTAGGAATGATCAT
CGTACCTTTCACGGAGCATTATTAGATAGTGAGCTGTTAGCGGATGTTTATCTAGCTATGACAGGTGGGCAGACTAATCT
AAGTCTGCAAACAGCCAAAACTGTGAGCAAAAATAGTATTGATATTGATGTCAATAAACTAAACTTACGTAATGCTGAAG
ATAGTATTAGCGATATTTCTGCACATCATAGTTATCTTAGTAATTTGCTAAAACTAGAAGAAGATGCAAAATGGTAA

Upstream 100 bases:

>100_bases
TAAATTCACGTAGTTCAAATTTTAAGGAAACCCAGAATTATCTTTCTATAAACTATACATTATATTTATAAGAATCTATT
GTTATAATTAGTCATTAGTA

Downstream 100 bases:

>100_bases
GAAAAATAATTTTTCCAGAAGCAAAAGAGCATGAGCTTATTTCGGCAGGTAAAGATTTTTTTGCTAGAGATTTACTTTTA
GAGAAAAATACTTATAAAGC

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIYILFFRMSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYKVEAGALAIHGLTNEFLADKPLFE
DKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDH
RTFHGALLDSELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW

Sequences:

>Translated_238_residues
MIYILFFRMSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYKVEAGALAIHGLTNEFLADKPLFE
DKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDH
RTFHGALLDSELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
>Mature_238_residues
MIYILFFRMSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYKVEAGALAIHGLTNEFLADKPLFE
DKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYGTLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDH
RTFHGALLDSELLADVYLAMTGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=239, Percent_Identity=43.0962343096234, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27192; Mature: 27192

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYILFFRMSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYKVEA
CEEEEEEEECCEEEEEECCCCCEEHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEEEE
GALAIHGLTNEFLADKPLFEDKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYG
CEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCCC
TLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALLDSELLADVYLAM
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEE
TGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
ECCCCCEEEEHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIYILFFRMSRQVFIDTETTGFDYKIGNRIIEFGAVEVIDRRITGNNLHFYCNPNYKVEA
CEEEEEEEECCEEEEEECCCCCEEHHCCHHHHHHHHHHHHHEECCCCEEEEECCCCEEEE
GALAIHGLTNEFLADKPLFEDKVDEMIEFLRGAEVIIHNAAFDVPFINWELSLLKNNKYG
CEEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEEECCCCC
TLEQNVAKIVDSLDLARKKHPLQKNNLDALCKRYQIRNDHRTFHGALLDSELLADVYLAM
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEE
TGGQTNLSLQTAKTVSKNSIDIDVNKLNLRNAEDSISDISAHHSYLSNLLKLEEDAKW
ECCCCCEEEEHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]