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The map label for this gene is clpX [H]

Identifier: 89256250

GI number: 89256250

Start: 870394

End: 871647

Strand: Direct

Name: clpX [H]

Synonym: FTL_0893

Alternate gene names: 89256250

Gene position: 870394-871647 (Clockwise)

Preceding gene: 89256249

Following gene: 89256251

Centisome position: 45.91

GC content: 32.38

Gene sequence:

>1254_bases
ATGGCTAAAATTCTATATTGTTCTTTTTGTGGTAAATCACAACAAGAAGTCAAAAATATTATCTCAGGAAGAGATGGTAA
TATTTGTAACGAATGTGTAAGTAAATGTGCCGAAAAAATTCGTAGTACTGGTAGTACTAGTGCTGAAGATATCTCATTTG
AAAAATTACCAAAGCCAGTTGAAATCAAAAAATACTTAGATGATTATATTATCGGTCAAGATAATGCTAAAAAAGTGTTA
TCAGTAGCTGTATACAATCATTATAAAAGAATTACATCTAACCTAACAAAAGATGATGATACTGAGCTTAAAAAAAGTAA
CGTGCTGTTAATTGGTCCAACGGGATCAGGTAAGACATTATTTGCCCAGACTTTAGCAAAGTTGTTAAATGTTCCTTTTG
CTATAGCAGATGCCACTACTCTTACTGAGGCTGGTTATGTTGGTGATGATGTTGAAAATATAATTGTTCGACTTTTGCAA
AATGCTGATTTTGATGTTGCTAAAGCACAAAAGGGTATTATTTATATTGATGAGATAGATAAAATCGCACGCAAATCAGA
AAGTACGTCAATAACTCGTGATGTTTCTGGTGAGGGTGTGCAGCAGGCATTATTAAAACTTATTGAGGGTACAGTGTCTT
CTGTGCCTCCTAAAGGCGGCAGAAAGCATCCTAATCAAGATATGATTCAAGTGGATACTTCAGATATATTATTTATTTGT
GGTGGAGCATTTGCTGGTATCGAGAAGGTTATAAAGCACAGAATGGATAAGGTCAGTATTGGGTTTAATGCTGATGTTAT
TCAACAAAAAAATAGCTTAGATAGCGATAAACTTATGCAAAAGATTGAAAGTGAAGATTTGACTAGATTTGGGCTTATTC
CAGAATTGATTGGTCGTTTGCCAATAGTTACAGTTCTAAATGAACTTAAAGAAGAAGATTTAGTTAGAATCCTTACAGAA
CCTAAAAATGCTTTAATTAAACAGTATATTAAGCTGTTTAAGTTTGATAATGTTAATATTGAGTTTACCGATCAAGCTCT
TGTTGAGATAGCTAAAAAAGCAATAACTAAAAAGACAGGCGCGAGAGGTCTAAGAACTATTTTAGAAAATGTACTTCTTG
AAGTGATGTTTCATATACCTTCATCTGAAGATATTGAAAAAGTTATTATCAATGACAAAGTAATTCTAGAGCAGCAAGAA
CCAATCTTAGCGATAAAAACACAACAGCAAAAACAATTAAAAGATATAATCTAA

Upstream 100 bases:

>100_bases
TTATGATGGCTGATGAAGCTAAAGCGTATGGTCTGATTGATCATGTGATTGAATCTCGTGAAGCAATTATTAAATAATTA
AAGGAAGTCAACTTACTAAA

Downstream 100 bases:

>100_bases
TAATTTACAGGAGGATGTAAGTTTATGTCAGAACCCCTAAATGTCGTTCCTGTTATTCCTTTAAGAGATGTTGTTATTTA
TCCATCGATGACTCTACCAC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPVEIKKYLDDYIIGQDNAKKVL
SVAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTLFAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQ
NADFDVAKAQKGIIYIDEIDKIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFIC
GGAFAGIEKVIKHRMDKVSIGFNADVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRLPIVTVLNELKEEDLVRILTE
PKNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTGARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQE
PILAIKTQQQKQLKDII

Sequences:

>Translated_417_residues
MAKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPVEIKKYLDDYIIGQDNAKKVL
SVAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTLFAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQ
NADFDVAKAQKGIIYIDEIDKIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFIC
GGAFAGIEKVIKHRMDKVSIGFNADVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRLPIVTVLNELKEEDLVRILTE
PKNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTGARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQE
PILAIKTQQQKQLKDII
>Mature_416_residues
AKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPVEIKKYLDDYIIGQDNAKKVLS
VAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTLFAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQN
ADFDVAKAQKGIIYIDEIDKIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFICG
GAFAGIEKVIKHRMDKVSIGFNADVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRLPIVTVLNELKEEDLVRILTEP
KNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTGARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQEP
ILAIKTQQQKQLKDII

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=327, Percent_Identity=48.0122324159021, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=412, Percent_Identity=61.4077669902913, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1790366, Length=214, Percent_Identity=37.8504672897196, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982908, Length=321, Percent_Identity=46.1059190031153, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=321, Percent_Identity=46.1059190031153, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=38.4039900249377, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=41.9354838709677, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=451, Percent_Identity=41.4634146341463, Blast_Score=289, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24648291, Length=305, Percent_Identity=45.5737704918033, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648289, Length=305, Percent_Identity=45.5737704918033, Blast_Score=284, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46320; Mature: 46189

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPV
CCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHHCCCCH
EIKKYLDDYIIGQDNAKKVLSVAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEECCCCCCHH
FAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQNADFDVAKAQKGIIYIDEID
HHHHHHHHHCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHCCCEEEEHHHH
KIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFIC
HHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEE
GGAFAGIEKVIKHRMDKVSIGFNADVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRL
CCHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHC
PIVTVLNELKEEDLVRILTEPKNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHC
ARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQEPILAIKTQQQKQLKDII
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure 
AKILYCSFCGKSQQEVKNIISGRDGNICNECVSKCAEKIRSTGSTSAEDISFEKLPKPV
CEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHHCCCCH
EIKKYLDDYIIGQDNAKKVLSVAVYNHYKRITSNLTKDDDTELKKSNVLLIGPTGSGKTL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEECCCCCCHH
FAQTLAKLLNVPFAIADATTLTEAGYVGDDVENIIVRLLQNADFDVAKAQKGIIYIDEID
HHHHHHHHHCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHCCCEEEEHHHH
KIARKSESTSITRDVSGEGVQQALLKLIEGTVSSVPPKGGRKHPNQDMIQVDTSDILFIC
HHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEE
GGAFAGIEKVIKHRMDKVSIGFNADVIQQKNSLDSDKLMQKIESEDLTRFGLIPELIGRL
CCHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHC
PIVTVLNELKEEDLVRILTEPKNALIKQYIKLFKFDNVNIEFTDQALVEIAKKAITKKTG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHC
ARGLRTILENVLLEVMFHIPSSEDIEKVIINDKVILEQQEPILAIKTQQQKQLKDII
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA