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The map label for this gene is hmuR [H]

Identifier: 89054623

GI number: 89054623

Start: 2138905

End: 2140974

Strand: Reverse

Name: hmuR [H]

Synonym: Jann_2132

Alternate gene names: 89054623

Gene position: 2140974-2138905 (Counterclockwise)

Preceding gene: 89054633

Following gene: 89054622

Centisome position: 49.58

GC content: 62.17

Gene sequence:

>2070_bases
ATGTCATACCGCATGGGACACGCGTGTCTTGGGCCGTCGACGGCCATGGCCGCGGCATTGGCCGTCTTGGCCGCACCGGG
ATACGCACAGGACACAACAACGCCACTGGGACGGATCATTCTAGGCTGGGGCACCGATCAGGTGGCGCTGGACACACCGC
AGGCCGTAACCGTCATCGACCAGGAAGAGATCGAGCGTCAGCAGGCCGCGACCATCGGCGAATTCTTCGACGGCGTGCCG
GGTGTGCAGGCCATCGGATCGGACCGCGTGTTAGGGCAAACCTTCAACATCCGTGGCTGGGGAGAGGTGCCCGCGGGCGA
TGAGGGGCGCGTGGTCGTGCTACAAGACGGCGCGACGCAGTATTATGAGCAATACCGGATGGGATCGTTCTTCTCGGACC
CCAACCTGTACTGCAACATCGAGGTTCTGCGAGGCCCCGCCTCGGCCACGCTTTACGGGTCAGGTGCCATCGGCGGCGTG
ATCCGGTTCGAGACCTGCGACGCCTCTGACTATCTGACCGAGGGCCAAACCAGCCAGTTCCGCTTCTCTCTGGGTGCCGA
GACGAACGGCGAAGGCGGCAATGTCGCCCTGCGCTACGCCACGCGATTGGGCGACAATTGGGAGGTCTTCACAAACCTGA
ACTACCGCGAGGCCGACGACTACGTGGACGGTGACGGCGACACGATTGAGGGCTCTGCGTTTGACAGCGCCTCGGCTCTG
ATCAGCGCGACCTACAGCTTTGACGCGAGCCGGTCAGTCAGGTTCATCTACGAGACCTGGAACAGCGATCTGGATGACAC
GTCCTATTCGCAAACCGGATCGGACGGTTTCGGCAACATCGACCGCCGCACCCGGGACCAGACCTTTTCGATGATCTACA
ACTCGGTCGAAGCGTTTGGCGATCTGGAAATGACGCTGGCCTATTCCGACACCGACGTGGAGCAAAGCGATTGGGAGGCC
ACCTTCCCCAGCTCCAGCGTGTTGTTCGAGGATACGGACTATGGCTACAGCACCATATCGCTCGACGGTCGGGTGACCAG
AGACATCACCCTGGGCGGGATCGACACGACGCTGATCTACGGGGCTACATTGGCCCAACAGGTCAGAGAGGCCGAGGCCC
AGACCTCAACCTTCATCGAGTTCCACCCCGAAGGTACCTCCATGCGCGCCGCCATTTTTGCTCAGGCCGAGATGGATTTC
GGCAACGGCCTGACCGTCGTGCCCGGCATGCGTCTGGAATATGCCCTGAACACACCCGGTGACGACAATGGGGGCACAGC
GCTCGACAGCCGCGAAGAGGTCGAGGTCATCTCCTTCTCGCCCAAGATCGCCTTCACCTACGATATCTCGGACCAATGGG
GCGTCTTCGGCTCCATCGCCCAGACGCAGCGCGCGCCGAACCTGGATGAGCTCTACTCGTACGACACCCGCGACGGTGAG
ACGCCCGCCACAGATCTGGACCCGGAGAACGCACGCTCCATCGAGTTGGGCTTCACCTACTCCCGCGCCGGTCTGCTGAA
CGCCGACGATGCATTCGATGCGCGCATTACGGCTTACTATTCCTACGTCGAGGATCTGATTGAACGCGATAGCCGGGCCG
GTACGCCGTATCATCGCAACATCGCCGAGGCCGAGATATACGGCGTTGAACTCGAAGCCGCCTATGTGTCGGAACGGTGG
TTCAGCAACCTGTCCCTGTCGGTCATCGAGGGCACCAACCTGACCGACGATGAGGTCTGGAGCCAACTGCCCCAGGACAC
GCTGTCCCTCACCCTCGGCGGACGGAATGCGGATCTTGGCATCGAATACGGCTGGCGAATGAACGCCTTCGCCGACATCG
ACTATGCCGACACGGTGTCGCGCGGCGTGGTCAACGACAACGTCTTTGCCGGCTACGCCACGCACGATCTGTTCGCCAGC
TGGGCCCCACAAGACGGGGCGCTGGAAGGGCTGGAGTTTCGCGCGGGCATCGATAACGTCTTTGACCGCACCTACACTAA
CGCGCTGGACGGTGACCCCGGACGCGGCATGACGGGCCGCCTGACGGTCGCGCGGGTGTGGAACTTCTGA

Upstream 100 bases:

>100_bases
GGTTCACGCCGGTCACTTTGCCGCGCATACCCCCACGATCTGCCAGCTGGAACGACCGGCAAGCACCACTTCAAAACAGC
AAACGCATGAGGGGGGTATG

Downstream 100 bases:

>100_bases
TGCGCGCGTTCCTGACCGCAACCCTCATCGCAGCCCTCCCTCTGGGGGTTGCGGCACAGGAGGCCCCGAGGCCGCTGATC
ATCGAATTGAACCGTATCGT

Product: TonB-dependentheme/hemoglobin receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MSYRMGHACLGPSTAMAAALAVLAAPGYAQDTTTPLGRIILGWGTDQVALDTPQAVTVIDQEEIERQQAATIGEFFDGVP
GVQAIGSDRVLGQTFNIRGWGEVPAGDEGRVVVLQDGATQYYEQYRMGSFFSDPNLYCNIEVLRGPASATLYGSGAIGGV
IRFETCDASDYLTEGQTSQFRFSLGAETNGEGGNVALRYATRLGDNWEVFTNLNYREADDYVDGDGDTIEGSAFDSASAL
ISATYSFDASRSVRFIYETWNSDLDDTSYSQTGSDGFGNIDRRTRDQTFSMIYNSVEAFGDLEMTLAYSDTDVEQSDWEA
TFPSSSVLFEDTDYGYSTISLDGRVTRDITLGGIDTTLIYGATLAQQVREAEAQTSTFIEFHPEGTSMRAAIFAQAEMDF
GNGLTVVPGMRLEYALNTPGDDNGGTALDSREEVEVISFSPKIAFTYDISDQWGVFGSIAQTQRAPNLDELYSYDTRDGE
TPATDLDPENARSIELGFTYSRAGLLNADDAFDARITAYYSYVEDLIERDSRAGTPYHRNIAEAEIYGVELEAAYVSERW
FSNLSLSVIEGTNLTDDEVWSQLPQDTLSLTLGGRNADLGIEYGWRMNAFADIDYADTVSRGVVNDNVFAGYATHDLFAS
WAPQDGALEGLEFRAGIDNVFDRTYTNALDGDPGRGMTGRLTVARVWNF

Sequences:

>Translated_689_residues
MSYRMGHACLGPSTAMAAALAVLAAPGYAQDTTTPLGRIILGWGTDQVALDTPQAVTVIDQEEIERQQAATIGEFFDGVP
GVQAIGSDRVLGQTFNIRGWGEVPAGDEGRVVVLQDGATQYYEQYRMGSFFSDPNLYCNIEVLRGPASATLYGSGAIGGV
IRFETCDASDYLTEGQTSQFRFSLGAETNGEGGNVALRYATRLGDNWEVFTNLNYREADDYVDGDGDTIEGSAFDSASAL
ISATYSFDASRSVRFIYETWNSDLDDTSYSQTGSDGFGNIDRRTRDQTFSMIYNSVEAFGDLEMTLAYSDTDVEQSDWEA
TFPSSSVLFEDTDYGYSTISLDGRVTRDITLGGIDTTLIYGATLAQQVREAEAQTSTFIEFHPEGTSMRAAIFAQAEMDF
GNGLTVVPGMRLEYALNTPGDDNGGTALDSREEVEVISFSPKIAFTYDISDQWGVFGSIAQTQRAPNLDELYSYDTRDGE
TPATDLDPENARSIELGFTYSRAGLLNADDAFDARITAYYSYVEDLIERDSRAGTPYHRNIAEAEIYGVELEAAYVSERW
FSNLSLSVIEGTNLTDDEVWSQLPQDTLSLTLGGRNADLGIEYGWRMNAFADIDYADTVSRGVVNDNVFAGYATHDLFAS
WAPQDGALEGLEFRAGIDNVFDRTYTNALDGDPGRGMTGRLTVARVWNF
>Mature_688_residues
SYRMGHACLGPSTAMAAALAVLAAPGYAQDTTTPLGRIILGWGTDQVALDTPQAVTVIDQEEIERQQAATIGEFFDGVPG
VQAIGSDRVLGQTFNIRGWGEVPAGDEGRVVVLQDGATQYYEQYRMGSFFSDPNLYCNIEVLRGPASATLYGSGAIGGVI
RFETCDASDYLTEGQTSQFRFSLGAETNGEGGNVALRYATRLGDNWEVFTNLNYREADDYVDGDGDTIEGSAFDSASALI
SATYSFDASRSVRFIYETWNSDLDDTSYSQTGSDGFGNIDRRTRDQTFSMIYNSVEAFGDLEMTLAYSDTDVEQSDWEAT
FPSSSVLFEDTDYGYSTISLDGRVTRDITLGGIDTTLIYGATLAQQVREAEAQTSTFIEFHPEGTSMRAAIFAQAEMDFG
NGLTVVPGMRLEYALNTPGDDNGGTALDSREEVEVISFSPKIAFTYDISDQWGVFGSIAQTQRAPNLDELYSYDTRDGET
PATDLDPENARSIELGFTYSRAGLLNADDAFDARITAYYSYVEDLIERDSRAGTPYHRNIAEAEIYGVELEAAYVSERWF
SNLSLSVIEGTNLTDDEVWSQLPQDTLSLTLGGRNADLGIEYGWRMNAFADIDYADTVSRGVVNDNVFAGYATHDLFASW
APQDGALEGLEFRAGIDNVFDRTYTNALDGDPGRGMTGRLTVARVWNF

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75338; Mature: 75206

Theoretical pI: Translated: 3.84; Mature: 3.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRMGHACLGPSTAMAAALAVLAAPGYAQDTTTPLGRIILGWGTDQVALDTPQAVTVID
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEC
QEEIERQQAATIGEFFDGVPGVQAIGSDRVLGQTFNIRGWGEVPAGDEGRVVVLQDGATQ
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECEEECCCCCCCCCCCCCCCEEEEECCCHH
YYEQYRMGSFFSDPNLYCNIEVLRGPASATLYGSGAIGGVIRFETCDASDYLTEGQTSQF
HHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCEEEEEECCCHHHHCCCCCCEE
RFSLGAETNGEGGNVALRYATRLGDNWEVFTNLNYREADDYVDGDGDTIEGSAFDSASAL
EEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCEE
ISATYSFDASRSVRFIYETWNSDLDDTSYSQTGSDGFGNIDRRTRDQTFSMIYNSVEAFG
EEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DLEMTLAYSDTDVEQSDWEATFPSSSVLFEDTDYGYSTISLDGRVTRDITLGGIDTTLIY
CEEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCEEEEEECCEEEEEEEECCCCCHHHH
GATLAQQVREAEAQTSTFIEFHPEGTSMRAAIFAQAEMDFGNGLTVVPGMRLEYALNTPG
HHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCCCCEEECCCCEEEEEECCCC
DDNGGTALDSREEVEVISFSPKIAFTYDISDQWGVFGSIAQTQRAPNLDELYSYDTRDGE
CCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCC
TPATDLDPENARSIELGFTYSRAGLLNADDAFDARITAYYSYVEDLIERDSRAGTPYHRN
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
IAEAEIYGVELEAAYVSERWFSNLSLSVIEGTNLTDDEVWSQLPQDTLSLTLGGRNADLG
CCCEEEEEEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCC
IEYGWRMNAFADIDYADTVSRGVVNDNVFAGYATHDLFASWAPQDGALEGLEFRAGIDNV
EEECCEECCEECCCHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCEEECCCHHHH
FDRTYTNALDGDPGRGMTGRLTVARVWNF
HHHHHCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SYRMGHACLGPSTAMAAALAVLAAPGYAQDTTTPLGRIILGWGTDQVALDTPQAVTVID
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEC
QEEIERQQAATIGEFFDGVPGVQAIGSDRVLGQTFNIRGWGEVPAGDEGRVVVLQDGATQ
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECEEECCCCCCCCCCCCCCCEEEEECCCHH
YYEQYRMGSFFSDPNLYCNIEVLRGPASATLYGSGAIGGVIRFETCDASDYLTEGQTSQF
HHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCEEEEEECCCHHHHCCCCCCEE
RFSLGAETNGEGGNVALRYATRLGDNWEVFTNLNYREADDYVDGDGDTIEGSAFDSASAL
EEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCEE
ISATYSFDASRSVRFIYETWNSDLDDTSYSQTGSDGFGNIDRRTRDQTFSMIYNSVEAFG
EEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DLEMTLAYSDTDVEQSDWEATFPSSSVLFEDTDYGYSTISLDGRVTRDITLGGIDTTLIY
CEEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCEEEEEECCEEEEEEEECCCCCHHHH
GATLAQQVREAEAQTSTFIEFHPEGTSMRAAIFAQAEMDFGNGLTVVPGMRLEYALNTPG
HHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCCCCEEECCCCEEEEEECCCC
DDNGGTALDSREEVEVISFSPKIAFTYDISDQWGVFGSIAQTQRAPNLDELYSYDTRDGE
CCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCC
TPATDLDPENARSIELGFTYSRAGLLNADDAFDARITAYYSYVEDLIERDSRAGTPYHRN
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
IAEAEIYGVELEAAYVSERWFSNLSLSVIEGTNLTDDEVWSQLPQDTLSLTLGGRNADLG
CCCEEEEEEEEEHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCCCCC
IEYGWRMNAFADIDYADTVSRGVVNDNVFAGYATHDLFASWAPQDGALEGLEFRAGIDNV
EEECCEECCEECCCHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCCCCCCEEECCCHHHH
FDRTYTNALDGDPGRGMTGRLTVARVWNF
HHHHHCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]