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The map label for this gene is coxL [H]

Identifier: 89054586

GI number: 89054586

Start: 2103494

End: 2105920

Strand: Reverse

Name: coxL [H]

Synonym: Jann_2095

Alternate gene names: 89054586

Gene position: 2105920-2103494 (Counterclockwise)

Preceding gene: 89054587

Following gene: 89054585

Centisome position: 48.77

GC content: 61.93

Gene sequence:

>2427_bases
ATGAAAGACGAAGTTTCGCGTGAGGAACGCATTGATAACCTCAAAGGCATGGGCTGCTCGCGCAAGCGGGTGGAGGATGC
ACGGTTCACCCAAGGCAAGGGCAATTACGTCGATGACATCAAGATGGATGGTATGCTGTTTGGCGATTTCGTCCGCTCCC
CCTATGCCCACGCTCGGGTCAAGAGCATCGACATTTCCGCCGCCATGGACGTCCCCGGTGTCCTCGCCGTTCTAACGGCG
GCGGATCTGGAGCCGCTTGGCCTGCACTGGATGCCGACGCTGGCGGGCGACAAGCAGATGGTGCTGGCCGACGGCAAGGT
CCTTTTTCAGGGCCAGGAAGTCGCCTTTGTGGTGGCCGAGGACCGCTACGCCGCCGCCGACGGGATTGAGTTGGTGGAGG
TCGACTACGAAGAGCTGCCCGTTCTGGTAAACCCGTTTGAGGCGCTGCAATCAGATGTCGTCCTGCGCGAGGATCTGGTG
GCAGAAGACGGCACGATCCCCGCCGGCGCCCACGGGCCGCGCAAGCATCCCAACCACATCTTCACGTGGGAAGCGGGCGA
CAAGGAGCCCACGGATCAGGTCATCGCGGACGCGGAGGTCGTGGCCGAGGAGAGCATGTACTACCACCGCACCCACCCCT
GCCCGCTGGAGACATGCGGCTGTGTGGCGAGCATGGACAAGGTCAACGGCAAGCTGACCCTTTGGGGCACGTTCCAGGCC
CCCCACGCGATCCGTACTGTGGTTTCCCTGATTTCCGGCATTGAGGAGCACAACATCCGTGTGATCAGCCCCGACATCGG
CGGTGGGTTCGGCAACAAGGTGGGGGCTTACCCGGGCTATGTCTGCTCTGTCGTGGCCTCCATCGTCACGGGCAAACCGG
TCAAGTGGATCGAAGACCGGATGGACAATCTGATGACCACCGCCTTCGCGCGGGATTACCACATGACGGGCCAGATCAGC
GCCACCAAGGAGGGCAAGATCACCGGCCTGAAATGCCACGTGACAGCGGATCACGGCGGTTTTGACGCCTGCGCCGACCC
GACCAAATTCCCGGCGGGCTTCATGAATATCTGCACCGGGTCCTACGACATCCCCACGGCATATCTGGAGGTCGATGGTG
TCTACACTAACAAGGCCCCGGGCGGCGTATCCTATCGCTGTTCCTTCCGGGTGACGGAGGCCGTTTACTTCATCGAACGG
ATGATCGAAGTCCTCGCCATCGAGCTGAACATGGACGCGGCAGAGCTGCGGCGGATCAACTTCATCAAGAAGGAGCAATT
TCCCTACACCGCCGCCCTTGGCTGGGAATACGACAGCGGCGACTACCACACGGCCTGGGACAAGGCGCTCAAGGCCGTGG
ACTACGATGGGCTGCGTGCGGAACAAGCGCAGCGTGTCGAAGATTTCAAGGCTGGAAAGACACGCAAACTGATGGGGATC
GGCCTGTCGTTCTTCACCGAGATCGTCGGTGCGGGCCCGGTGAAGAACTGCGATATCCTCGGCCTCGGCATGTTCGACAG
CTGTGAGATCCGCATCCACCCCACGGGGTCTGCGATTGCGCGCCTCGGGACGATCAGCCAGGGCCAGGGTCACGCGACGA
CGTTTGCGCAAATCCTGGCCTCGGAAATCGGCCTGCCCGCCGACAGTATAACGATTGAAGAAGGCGACACCGACACGGCC
CCCTACGGGCTTGGCACCTACGGCTCCCGCTCCACCCCCGTTGCAGGGGCGGCCACCGCCATGGCCGGTCGCAAGATCCG
CGCCAAAGCGCAGATGATCGCGGCCTATCTGCTGGAGGTCCACGACAATGACGTGGAGTTCGACGTGGATCGCTTCGTCG
TAAAAGGCGCGCCGGAGCAGTTCAAAACCATGAAGGAAGTGGCCTTTGCCGCCTATAATCAGGCCATTCCGGGGTTGGAG
CCGGGCCTAGAGGCGGTCAGCTACTATGATCCGCCCAACATGACCTATCCCTTCGGGGCTTACGTCTGCGTCATGGATAT
CGACGTCGACACCGGTGTGCCAGAGATCCGCCGCTTCTACGCGCTGGACGATTGCGGCACGCGGATCAACCCGATGATCA
TCGAAGGACAGGTCCACGGCGGTTTGACCGAAGCGCTGGCCGTCGCCCTGGGGCAGGAGATCGCCTATGACGACATGGGC
AACTGCAAGACCGGCACGTTGATGGACTTCTTCCTGCCCACGGCTTGGGAGGTCCCGAATTATGAGACCGACTTCACCGT
CACGCCCTCTCCGCACCATCCCATCGGGGCGAAGGGGGTGGGCGAAAGCCCCCATGTGGGCGGGGTGCCGTGCTTCTCCA
ACGCGGTGCAGGACGCATTCCGCCCCTTCGGCAATCGGCACACCAACATGCCCCATGACCATTGGCGGATCTGGAAGACC
GCGAATGATCTTGGCCTGCACGGATAA

Upstream 100 bases:

>100_bases
AGCAGGGCCGCATCCCGGCACCATGTGGGACAGCCGTAGGCCATCGAGTAATGGCCTCAAGTAACGAAGTGGTAGGCCAA
GACGAAAGAGGGGCGGCGGA

Downstream 100 bases:

>100_bases
GGGACAAGGTCCGGCGGCGCGCGCCCTCGCCGGACCGGTTTTCACATGACATGGACTGACCTGAAATCTTCGCTGGCGGC
TGAGGGCTATGTGGCCTCGG

Product: carbon monoxide dehydrogenase, large subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MKDEVSREERIDNLKGMGCSRKRVEDARFTQGKGNYVDDIKMDGMLFGDFVRSPYAHARVKSIDISAAMDVPGVLAVLTA
ADLEPLGLHWMPTLAGDKQMVLADGKVLFQGQEVAFVVAEDRYAAADGIELVEVDYEELPVLVNPFEALQSDVVLREDLV
AEDGTIPAGAHGPRKHPNHIFTWEAGDKEPTDQVIADAEVVAEESMYYHRTHPCPLETCGCVASMDKVNGKLTLWGTFQA
PHAIRTVVSLISGIEEHNIRVISPDIGGGFGNKVGAYPGYVCSVVASIVTGKPVKWIEDRMDNLMTTAFARDYHMTGQIS
ATKEGKITGLKCHVTADHGGFDACADPTKFPAGFMNICTGSYDIPTAYLEVDGVYTNKAPGGVSYRCSFRVTEAVYFIER
MIEVLAIELNMDAAELRRINFIKKEQFPYTAALGWEYDSGDYHTAWDKALKAVDYDGLRAEQAQRVEDFKAGKTRKLMGI
GLSFFTEIVGAGPVKNCDILGLGMFDSCEIRIHPTGSAIARLGTISQGQGHATTFAQILASEIGLPADSITIEEGDTDTA
PYGLGTYGSRSTPVAGAATAMAGRKIRAKAQMIAAYLLEVHDNDVEFDVDRFVVKGAPEQFKTMKEVAFAAYNQAIPGLE
PGLEAVSYYDPPNMTYPFGAYVCVMDIDVDTGVPEIRRFYALDDCGTRINPMIIEGQVHGGLTEALAVALGQEIAYDDMG
NCKTGTLMDFFLPTAWEVPNYETDFTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVQDAFRPFGNRHTNMPHDHWRIWKT
ANDLGLHG

Sequences:

>Translated_808_residues
MKDEVSREERIDNLKGMGCSRKRVEDARFTQGKGNYVDDIKMDGMLFGDFVRSPYAHARVKSIDISAAMDVPGVLAVLTA
ADLEPLGLHWMPTLAGDKQMVLADGKVLFQGQEVAFVVAEDRYAAADGIELVEVDYEELPVLVNPFEALQSDVVLREDLV
AEDGTIPAGAHGPRKHPNHIFTWEAGDKEPTDQVIADAEVVAEESMYYHRTHPCPLETCGCVASMDKVNGKLTLWGTFQA
PHAIRTVVSLISGIEEHNIRVISPDIGGGFGNKVGAYPGYVCSVVASIVTGKPVKWIEDRMDNLMTTAFARDYHMTGQIS
ATKEGKITGLKCHVTADHGGFDACADPTKFPAGFMNICTGSYDIPTAYLEVDGVYTNKAPGGVSYRCSFRVTEAVYFIER
MIEVLAIELNMDAAELRRINFIKKEQFPYTAALGWEYDSGDYHTAWDKALKAVDYDGLRAEQAQRVEDFKAGKTRKLMGI
GLSFFTEIVGAGPVKNCDILGLGMFDSCEIRIHPTGSAIARLGTISQGQGHATTFAQILASEIGLPADSITIEEGDTDTA
PYGLGTYGSRSTPVAGAATAMAGRKIRAKAQMIAAYLLEVHDNDVEFDVDRFVVKGAPEQFKTMKEVAFAAYNQAIPGLE
PGLEAVSYYDPPNMTYPFGAYVCVMDIDVDTGVPEIRRFYALDDCGTRINPMIIEGQVHGGLTEALAVALGQEIAYDDMG
NCKTGTLMDFFLPTAWEVPNYETDFTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVQDAFRPFGNRHTNMPHDHWRIWKT
ANDLGLHG
>Mature_808_residues
MKDEVSREERIDNLKGMGCSRKRVEDARFTQGKGNYVDDIKMDGMLFGDFVRSPYAHARVKSIDISAAMDVPGVLAVLTA
ADLEPLGLHWMPTLAGDKQMVLADGKVLFQGQEVAFVVAEDRYAAADGIELVEVDYEELPVLVNPFEALQSDVVLREDLV
AEDGTIPAGAHGPRKHPNHIFTWEAGDKEPTDQVIADAEVVAEESMYYHRTHPCPLETCGCVASMDKVNGKLTLWGTFQA
PHAIRTVVSLISGIEEHNIRVISPDIGGGFGNKVGAYPGYVCSVVASIVTGKPVKWIEDRMDNLMTTAFARDYHMTGQIS
ATKEGKITGLKCHVTADHGGFDACADPTKFPAGFMNICTGSYDIPTAYLEVDGVYTNKAPGGVSYRCSFRVTEAVYFIER
MIEVLAIELNMDAAELRRINFIKKEQFPYTAALGWEYDSGDYHTAWDKALKAVDYDGLRAEQAQRVEDFKAGKTRKLMGI
GLSFFTEIVGAGPVKNCDILGLGMFDSCEIRIHPTGSAIARLGTISQGQGHATTFAQILASEIGLPADSITIEEGDTDTA
PYGLGTYGSRSTPVAGAATAMAGRKIRAKAQMIAAYLLEVHDNDVEFDVDRFVVKGAPEQFKTMKEVAFAAYNQAIPGLE
PGLEAVSYYDPPNMTYPFGAYVCVMDIDVDTGVPEIRRFYALDDCGTRINPMIIEGQVHGGLTEALAVALGQEIAYDDMG
NCKTGTLMDFFLPTAWEVPNYETDFTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVQDAFRPFGNRHTNMPHDHWRIWKT
ANDLGLHG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=788, Percent_Identity=23.0964467005076, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI71773480, Length=775, Percent_Identity=22.4516129032258, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1789230, Length=779, Percent_Identity=26.5725288831836, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789246, Length=804, Percent_Identity=25.7462686567164, Blast_Score=206, Evalue=7e-54,
Organism=Escherichia coli, GI1786478, Length=793, Percent_Identity=24.0857503152585, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=793, Percent_Identity=23.203026481715, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647201, Length=796, Percent_Identity=21.7336683417085, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 88068; Mature: 88068

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDEVSREERIDNLKGMGCSRKRVEDARFTQGKGNYVDDIKMDGMLFGDFVRSPYAHARV
CCCCCCHHHHHHHHCCCCCCHHHHCHHHCCCCCCCCCCCEEECCEEEHHHHCCCHHHHEE
KSIDISAAMDVPGVLAVLTAADLEPLGLHWMPTLAGDKQMVLADGKVLFQGQEVAFVVAE
EEEEEEHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCEEEEECCEEEEEEEC
DRYAAADGIELVEVDYEELPVLVNPFEALQSDVVLREDLVAEDGTIPAGAHGPRKHPNHI
CCCCCCCCCEEEEECHHHCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
FTWEAGDKEPTDQVIADAEVVAEESMYYHRTHPCPLETCGCVASMDKVNGKLTLWGTFQA
EEECCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
PHAIRTVVSLISGIEEHNIRVISPDIGGGFGNKVGAYPGYVCSVVASIVTGKPVKWIEDR
CHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
MDNLMTTAFARDYHMTGQISATKEGKITGLKCHVTADHGGFDACADPTKFPAGFMNICTG
HHHHHHHHHHHCEEECCEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCC
SYDIPTAYLEVDGVYTNKAPGGVSYRCSFRVTEAVYFIERMIEVLAIELNMDAAELRRIN
CCCCCEEEEEECCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
FIKKEQFPYTAALGWEYDSGDYHTAWDKALKAVDYDGLRAEQAQRVEDFKAGKTRKLMGI
HHHHCCCCEEEEECEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHC
GLSFFTEIVGAGPVKNCDILGLGMFDSCEIRIHPTGSAIARLGTISQGQGHATTFAQILA
CHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHH
SEIGLPADSITIEEGDTDTAPYGLGTYGSRSTPVAGAATAMAGRKIRAKAQMIAAYLLEV
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
HDNDVEFDVDRFVVKGAPEQFKTMKEVAFAAYNQAIPGLEPGLEAVSYYDPPNMTYPFGA
CCCCCEEEHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCCE
YVCVMDIDVDTGVPEIRRFYALDDCGTRINPMIIEGQVHGGLTEALAVALGQEIAYDDMG
EEEEEEEECCCCCHHHHHHEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHCCCCCC
NCKTGTLMDFFLPTAWEVPNYETDFTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVQDAF
CCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RPFGNRHTNMPHDHWRIWKTANDLGLHG
HHCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKDEVSREERIDNLKGMGCSRKRVEDARFTQGKGNYVDDIKMDGMLFGDFVRSPYAHARV
CCCCCCHHHHHHHHCCCCCCHHHHCHHHCCCCCCCCCCCEEECCEEEHHHHCCCHHHHEE
KSIDISAAMDVPGVLAVLTAADLEPLGLHWMPTLAGDKQMVLADGKVLFQGQEVAFVVAE
EEEEEEHHCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCEEEEECCEEEEEEEC
DRYAAADGIELVEVDYEELPVLVNPFEALQSDVVLREDLVAEDGTIPAGAHGPRKHPNHI
CCCCCCCCCEEEEECHHHCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
FTWEAGDKEPTDQVIADAEVVAEESMYYHRTHPCPLETCGCVASMDKVNGKLTLWGTFQA
EEECCCCCCCHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
PHAIRTVVSLISGIEEHNIRVISPDIGGGFGNKVGAYPGYVCSVVASIVTGKPVKWIEDR
CHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
MDNLMTTAFARDYHMTGQISATKEGKITGLKCHVTADHGGFDACADPTKFPAGFMNICTG
HHHHHHHHHHHCEEECCEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCC
SYDIPTAYLEVDGVYTNKAPGGVSYRCSFRVTEAVYFIERMIEVLAIELNMDAAELRRIN
CCCCCEEEEEECCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHEEEEECCCHHHHHHHH
FIKKEQFPYTAALGWEYDSGDYHTAWDKALKAVDYDGLRAEQAQRVEDFKAGKTRKLMGI
HHHHCCCCEEEEECEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHC
GLSFFTEIVGAGPVKNCDILGLGMFDSCEIRIHPTGSAIARLGTISQGQGHATTFAQILA
CHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHH
SEIGLPADSITIEEGDTDTAPYGLGTYGSRSTPVAGAATAMAGRKIRAKAQMIAAYLLEV
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
HDNDVEFDVDRFVVKGAPEQFKTMKEVAFAAYNQAIPGLEPGLEAVSYYDPPNMTYPFGA
CCCCCEEEHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCCE
YVCVMDIDVDTGVPEIRRFYALDDCGTRINPMIIEGQVHGGLTEALAVALGQEIAYDDMG
EEEEEEEECCCCCHHHHHHEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHCCCCCC
NCKTGTLMDFFLPTAWEVPNYETDFTVTPSPHHPIGAKGVGESPHVGGVPCFSNAVQDAF
CCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RPFGNRHTNMPHDHWRIWKTANDLGLHG
HHCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]