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The map label for this gene is coxS [H]

Identifier: 89054587

GI number: 89054587

Start: 2106030

End: 2106524

Strand: Reverse

Name: coxS [H]

Synonym: Jann_2096

Alternate gene names: 89054587

Gene position: 2106524-2106030 (Counterclockwise)

Preceding gene: 89054588

Following gene: 89054586

Centisome position: 48.78

GC content: 60.81

Gene sequence:

>495_bases
ATGCCTAAGAAAATGCACATCACGCTCAACGTGAACGGCAAGGAAGAGGAATTCCTGGCCGAGCCGCGCGAATTGCTGAT
CTATACGCTGCGCGAGCGGCTCAACATCACCGGGCCGCATATCGGGTGCGAGACGTCCCATTGCGGGGCCTGCACCGTCA
CGATCAACGGCAAATCGGTCAAATCCTGCACCATGTTCGTGGCCCAGGCTGACGGAGCCGAGGTCACGACCATCGAAGGC
ATCGGCGGGCCGGACGCCCTGCACCCGTTGCAGACCGCGTTCAAGGAACATCACGGGCTTCAGTGCGGCTATTGCACGCC
GGGCATGATCACCCGCGCCCAAAAGCTGCTCGAAGAAAACCCGAACCCGACAGAGGAAGACATCCGCTTCGGCATGGCGG
GCAACATCTGCCGCTGCACGGGCTACCAGAACATTGTGAAGAGCATTCAGGCGGCTGCGGCTGAGATGAATGCGGCCAAG
GAGGCAGCGGAATGA

Upstream 100 bases:

>100_bases
GCCCCGTCGCCTTCAAGAACCACGTGGCAGGCGTCATCCTGCGCCGCGCGATCGAACGCGCTTGGTCACGCGCCTAAGCA
GCGTCAGGGAGAAACACACT

Downstream 100 bases:

>100_bases
GTATCGCGAAGCAGGGCCGCATCCCGGCACCATGTGGGACAGCCGTAGGCCATCGAGTAATGGCCTCAAGTAACGAAGTG
GTAGGCCAAGACGAAAGAGG

Product: carbon monoxide dehydrogenase, small subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPKKMHITLNVNGKEEEFLAEPRELLIYTLRERLNITGPHIGCETSHCGACTVTINGKSVKSCTMFVAQADGAEVTTIEG
IGGPDALHPLQTAFKEHHGLQCGYCTPGMITRAQKLLEENPNPTEEDIRFGMAGNICRCTGYQNIVKSIQAAAAEMNAAK
EAAE

Sequences:

>Translated_164_residues
MPKKMHITLNVNGKEEEFLAEPRELLIYTLRERLNITGPHIGCETSHCGACTVTINGKSVKSCTMFVAQADGAEVTTIEG
IGGPDALHPLQTAFKEHHGLQCGYCTPGMITRAQKLLEENPNPTEEDIRFGMAGNICRCTGYQNIVKSIQAAAAEMNAAK
EAAE
>Mature_163_residues
PKKMHITLNVNGKEEEFLAEPRELLIYTLRERLNITGPHIGCETSHCGACTVTINGKSVKSCTMFVAQADGAEVTTIEGI
GGPDALHPLQTAFKEHHGLQCGYCTPGMITRAQKLLEENPNPTEEDIRFGMAGNICRCTGYQNIVKSIQAAAAEMNAAKE
AAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=36.4779874213836, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI71773480, Length=160, Percent_Identity=33.125, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1786480, Length=172, Percent_Identity=43.6046511627907, Blast_Score=151, Evalue=2e-38,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=39.041095890411, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=170, Percent_Identity=41.7647058823529, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.012987012987, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=35.625, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17737937, Length=162, Percent_Identity=36.4197530864198, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647197, Length=168, Percent_Identity=32.1428571428571, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24647195, Length=168, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=165, Percent_Identity=32.7272727272727, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647199, Length=136, Percent_Identity=33.0882352941176, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647201, Length=160, Percent_Identity=31.25, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17761; Mature: 17629

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKMHITLNVNGKEEEFLAEPRELLIYTLRERLNITGPHIGCETSHCGACTVTINGKSV
CCCEEEEEEEECCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCC
KSCTMFVAQADGAEVTTIEGIGGPDALHPLQTAFKEHHGLQCGYCTPGMITRAQKLLEEN
CEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
PNPTEEDIRFGMAGNICRCTGYQNIVKSIQAAAAEMNAAKEAAE
CCCCHHHHEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKKMHITLNVNGKEEEFLAEPRELLIYTLRERLNITGPHIGCETSHCGACTVTINGKSV
CCEEEEEEEECCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCC
KSCTMFVAQADGAEVTTIEGIGGPDALHPLQTAFKEHHGLQCGYCTPGMITRAQKLLEEN
CEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
PNPTEEDIRFGMAGNICRCTGYQNIVKSIQAAAAEMNAAKEAAE
CCCCHHHHEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]