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The map label for this gene is dppB [H]

Identifier: 89054536

GI number: 89054536

Start: 2049181

End: 2050236

Strand: Reverse

Name: dppB [H]

Synonym: Jann_2045

Alternate gene names: 89054536

Gene position: 2050236-2049181 (Counterclockwise)

Preceding gene: 89054541

Following gene: 89054535

Centisome position: 47.48

GC content: 62.69

Gene sequence:

>1056_bases
ATGACCTTCCAAGACATCAGACCCACCATGATCAGCAGCACAGCCCTTGGGCTCTTGCGGTTTGTGATCGTCGTGGCCCT
GACGTTTCTGGGCCTTCTGGCGCTGACATTTTTCATCGGGCGCGTGGTGCCGATTGACCCGGTCCTGGCCGTGGTGGGCG
ACCGTGCCACGCCGGAGCAGTACGAGGTCGCGCGCGTTGCCATGGGCCTGGACCGTCCGCTTGTCGTTCAATTCATCAGC
TACGTGGGCGACGTGCTGCGCTTTGATCTGGGCCTGTCGACCTCCACCAACCGGCCCGTGGCCGAAGACCTCGCGCGGGT
GTTTCCGGCCACGTTGGAGATGGCAACGCTTGGCATCCTCATCGGCGTGGGCCTTGGTGTGCCTGCCGGCGTTCTGGCCG
CCGCATGGCAGGGCAGCTGGGTGGATCAGATCATTCGCGTCTTCGCCCTTATGGGCTATTCGGTGCCTGCCTTCTGGCTC
GGCCTCGTGGGCCTCGCCGTCTTCTACGCTTGGCTCGGCTGGGTGGAGGGGCCGGGCCGCGTCAGCATCTTCTACGACGG
GATCACACCTGTGGTGACGGGCCTTTTGACCGTGGATGCGCTGCTTGATGGCGACTGGACCGTCTTCAGAAGCGCGTGGT
CGCATATCATCCTGCCCGCTGCGATCCTTGGGGTCTTCTCCTTGGCCTATATCGCGCGAATGACGCGGTCTTTCATGCTG
GATCAACTCAGCCAGGAATACATCACCACCGCGCGCGTCAAAGGTGTGGCGGAGTGGCGGGTGATCTGGGTCCATGCGTT
CGGCTCCATCCGGGTGCCGCTGATCACCGTCATCGGGCTATCCTATGCGGGCCTGCTGGAAGGGTCCGTGATGATCGAGA
CGGTCTTCTCGTGGCCCGGCATCGGCAACTATCTGACAACCGCCTTGTTCAACGCCGATATGAACGCGGTCCTCGGCGCG
ACGCTGGTCATTGGCGCGGTGTTCATCCTGATCAACAAAGTGTCTGACCTGCTTTACCGCATTCTCGACCCCCGCTCACG
CGATGGGAGCCGCTGA

Upstream 100 bases:

>100_bases
TTTTTGATCTAAGCAAAACTATTTGCCAAAACCAAGCGAAATGTTGCACCGTCGGGGCGTGGCCGGCCCGTCGCCGCCGC
CGAAAGGGCCGCCGAAACCG

Downstream 100 bases:

>100_bases
CATGCGCGACTGGCTTCTGGACGACAGCCCGTCGTCGCGCACCCAAGCCGCATCGGGGCGGGCGTATCGCATCACGCTGG
ACCTGCTGCGCAACCCCCTG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTFQDIRPTMISSTALGLLRFVIVVALTFLGLLALTFFIGRVVPIDPVLAVVGDRATPEQYEVARVAMGLDRPLVVQFIS
YVGDVLRFDLGLSTSTNRPVAEDLARVFPATLEMATLGILIGVGLGVPAGVLAAAWQGSWVDQIIRVFALMGYSVPAFWL
GLVGLAVFYAWLGWVEGPGRVSIFYDGITPVVTGLLTVDALLDGDWTVFRSAWSHIILPAAILGVFSLAYIARMTRSFML
DQLSQEYITTARVKGVAEWRVIWVHAFGSIRVPLITVIGLSYAGLLEGSVMIETVFSWPGIGNYLTTALFNADMNAVLGA
TLVIGAVFILINKVSDLLYRILDPRSRDGSR

Sequences:

>Translated_351_residues
MTFQDIRPTMISSTALGLLRFVIVVALTFLGLLALTFFIGRVVPIDPVLAVVGDRATPEQYEVARVAMGLDRPLVVQFIS
YVGDVLRFDLGLSTSTNRPVAEDLARVFPATLEMATLGILIGVGLGVPAGVLAAAWQGSWVDQIIRVFALMGYSVPAFWL
GLVGLAVFYAWLGWVEGPGRVSIFYDGITPVVTGLLTVDALLDGDWTVFRSAWSHIILPAAILGVFSLAYIARMTRSFML
DQLSQEYITTARVKGVAEWRVIWVHAFGSIRVPLITVIGLSYAGLLEGSVMIETVFSWPGIGNYLTTALFNADMNAVLGA
TLVIGAVFILINKVSDLLYRILDPRSRDGSR
>Mature_350_residues
TFQDIRPTMISSTALGLLRFVIVVALTFLGLLALTFFIGRVVPIDPVLAVVGDRATPEQYEVARVAMGLDRPLVVQFISY
VGDVLRFDLGLSTSTNRPVAEDLARVFPATLEMATLGILIGVGLGVPAGVLAAAWQGSWVDQIIRVFALMGYSVPAFWLG
LVGLAVFYAWLGWVEGPGRVSIFYDGITPVVTGLLTVDALLDGDWTVFRSAWSHIILPAAILGVFSLAYIARMTRSFMLD
QLSQEYITTARVKGVAEWRVIWVHAFGSIRVPLITVIGLSYAGLLEGSVMIETVFSWPGIGNYLTTALFNADMNAVLGAT
LVIGAVFILINKVSDLLYRILDPRSRDGSR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=39.5833333333333, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787761, Length=325, Percent_Identity=43.6923076923077, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=34.185303514377, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789888, Length=291, Percent_Identity=33.6769759450172, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1787550, Length=271, Percent_Identity=30.9963099630996, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=29.4642857142857, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788504, Length=372, Percent_Identity=25.2688172043011, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38131; Mature: 38000

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQDIRPTMISSTALGLLRFVIVVALTFLGLLALTFFIGRVVPIDPVLAVVGDRATPEQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
YEVARVAMGLDRPLVVQFISYVGDVLRFDLGLSTSTNRPVAEDLARVFPATLEMATLGIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGVGLGVPAGVLAAAWQGSWVDQIIRVFALMGYSVPAFWLGLVGLAVFYAWLGWVEGPGR
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VSIFYDGITPVVTGLLTVDALLDGDWTVFRSAWSHIILPAAILGVFSLAYIARMTRSFML
EEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLSQEYITTARVKGVAEWRVIWVHAFGSIRVPLITVIGLSYAGLLEGSVMIETVFSWPG
HHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
IGNYLTTALFNADMNAVLGATLVIGAVFILINKVSDLLYRILDPRSRDGSR
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TFQDIRPTMISSTALGLLRFVIVVALTFLGLLALTFFIGRVVPIDPVLAVVGDRATPEQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
YEVARVAMGLDRPLVVQFISYVGDVLRFDLGLSTSTNRPVAEDLARVFPATLEMATLGIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGVGLGVPAGVLAAAWQGSWVDQIIRVFALMGYSVPAFWLGLVGLAVFYAWLGWVEGPGR
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VSIFYDGITPVVTGLLTVDALLDGDWTVFRSAWSHIILPAAILGVFSLAYIARMTRSFML
EEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLSQEYITTARVKGVAEWRVIWVHAFGSIRVPLITVIGLSYAGLLEGSVMIETVFSWPG
HHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
IGNYLTTALFNADMNAVLGATLVIGAVFILINKVSDLLYRILDPRSRDGSR
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]