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The map label for this gene is chbR [H]

Identifier: 89054541

GI number: 89054541

Start: 2054779

End: 2055633

Strand: Reverse

Name: chbR [H]

Synonym: Jann_2050

Alternate gene names: 89054541

Gene position: 2055633-2054779 (Counterclockwise)

Preceding gene: 89054550

Following gene: 89054536

Centisome position: 47.61

GC content: 62.46

Gene sequence:

>855_bases
ATGCGCTTACCCCAGAAGATGTTCAAAATTGATACCTACCTCAGCCCCGGCGAGGCGTTTCATTTTGTGCGCAAGGAGCT
ATCGGAAGCCTCACCCGTGTTGGAGCATGACCACGATTACTATGAGCTGTTCCTGATCCAGCAGGGTCAGGTCTATCATT
GGATCAACGGGCTAGAAGAGATGTTGGAGCCCGGCCACATGGTGTTTGTTCGCCCGTCCGACCGTCACGCCCTGCAAGGG
GCACCGGGCACCGGCGCGAAAATCCTGAACGTGATGTTCCGAACCCAGACCGCGGCGCATCTGGTGACGCGGTACGCGGA
TGTGTTCGGGGGGCGGTTCTTCTGGCAACCGGGGCCCCTGCCCGTGACGTTGCGCCTCCACGGCCCGCAGCGGGAACGCG
CGATCAACTCCATGTTGACGCTCGACACCAGCTTCCGAAACCTGGCGCGGATCGAGCTGTTCCTGCTGTCGGTCATGACC
CATGTGCTGGATACCGGCGAGATCGTCGATGGTCGCGCCCCGGGCTGGTTGTTGCAGGCGTGCCACGCGGCCCGTGAGCC
GCGCGTGTTTCGCCAGGGCGCGGATGGGTTCTTGCACGCCGCCGGCCGCTCGCAAGCCCATGTGTGCCGACAAGCGCGCC
GATACCTCGGCCTGTCGCCAACGCAATATGTCAATCGCATCCGCATCCAGCACGCGGCCATGCTCTTGGCGGGAACGGAA
CGTGGCCTGCCGGACATCGCTGCCGATTGTGGGTTTGAAAACCTGAGCTACTTTCACCGTCTGTTTCGCGAGCAATATGG
CACAACGCCCCGCGGCTACCGCCACCGTCATGTGCGTCCGATCGCACCGCTTTAG

Upstream 100 bases:

>100_bases
TCGCGGTTCATGGTCTGCGCGCAGACCCAAGCTTGACAAAAACATGCACAGGATTGATCTTTTGATAGATCATGCTGCAA
CTGCAAAATAGCTGTTCCAT

Downstream 100 bases:

>100_bases
GCGGAGGCCTGTGACCTTGGCTTGCGCGCTTGGGATCGCGTGACCTGCATCGAGCCGGTCTATGCCCATGACTCCCCAAT
GGCTTGGCGACCGGGCCGTC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MRLPQKMFKIDTYLSPGEAFHFVRKELSEASPVLEHDHDYYELFLIQQGQVYHWINGLEEMLEPGHMVFVRPSDRHALQG
APGTGAKILNVMFRTQTAAHLVTRYADVFGGRFFWQPGPLPVTLRLHGPQRERAINSMLTLDTSFRNLARIELFLLSVMT
HVLDTGEIVDGRAPGWLLQACHAAREPRVFRQGADGFLHAAGRSQAHVCRQARRYLGLSPTQYVNRIRIQHAAMLLAGTE
RGLPDIAADCGFENLSYFHRLFREQYGTTPRGYRHRHVRPIAPL

Sequences:

>Translated_284_residues
MRLPQKMFKIDTYLSPGEAFHFVRKELSEASPVLEHDHDYYELFLIQQGQVYHWINGLEEMLEPGHMVFVRPSDRHALQG
APGTGAKILNVMFRTQTAAHLVTRYADVFGGRFFWQPGPLPVTLRLHGPQRERAINSMLTLDTSFRNLARIELFLLSVMT
HVLDTGEIVDGRAPGWLLQACHAAREPRVFRQGADGFLHAAGRSQAHVCRQARRYLGLSPTQYVNRIRIQHAAMLLAGTE
RGLPDIAADCGFENLSYFHRLFREQYGTTPRGYRHRHVRPIAPL
>Mature_284_residues
MRLPQKMFKIDTYLSPGEAFHFVRKELSEASPVLEHDHDYYELFLIQQGQVYHWINGLEEMLEPGHMVFVRPSDRHALQG
APGTGAKILNVMFRTQTAAHLVTRYADVFGGRFFWQPGPLPVTLRLHGPQRERAINSMLTLDTSFRNLARIELFLLSVMT
HVLDTGEIVDGRAPGWLLQACHAAREPRVFRQGADGFLHAAGRSQAHVCRQARRYLGLSPTQYVNRIRIQHAAMLLAGTE
RGLPDIAADCGFENLSYFHRLFREQYGTTPRGYRHRHVRPIAPL

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=275, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32447; Mature: 32447

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPQKMFKIDTYLSPGEAFHFVRKELSEASPVLEHDHDYYELFLIQQGQVYHWINGLEE
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEECCCHHHHHHHHHH
MLEPGHMVFVRPSDRHALQGAPGTGAKILNVMFRTQTAAHLVTRYADVFGGRFFWQPGPL
HCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
PVTLRLHGPQRERAINSMLTLDTSFRNLARIELFLLSVMTHVLDTGEIVDGRAPGWLLQA
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
CHAAREPRVFRQGADGFLHAAGRSQAHVCRQARRYLGLSPTQYVNRIRIQHAAMLLAGTE
HHHHCCCHHHHCCCCHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RGLPDIAADCGFENLSYFHRLFREQYGTTPRGYRHRHVRPIAPL
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLPQKMFKIDTYLSPGEAFHFVRKELSEASPVLEHDHDYYELFLIQQGQVYHWINGLEE
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEECCCHHHHHHHHHH
MLEPGHMVFVRPSDRHALQGAPGTGAKILNVMFRTQTAAHLVTRYADVFGGRFFWQPGPL
HCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
PVTLRLHGPQRERAINSMLTLDTSFRNLARIELFLLSVMTHVLDTGEIVDGRAPGWLLQA
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
CHAAREPRVFRQGADGFLHAAGRSQAHVCRQARRYLGLSPTQYVNRIRIQHAAMLLAGTE
HHHHCCCHHHHCCCCHHEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RGLPDIAADCGFENLSYFHRLFREQYGTTPRGYRHRHVRPIAPL
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]