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The map label for this gene is siaT [H]

Identifier: 89054528

GI number: 89054528

Start: 2042505

End: 2043812

Strand: Direct

Name: siaT [H]

Synonym: Jann_2037

Alternate gene names: 89054528

Gene position: 2042505-2043812 (Clockwise)

Preceding gene: 89054527

Following gene: 89054529

Centisome position: 47.3

GC content: 61.62

Gene sequence:

>1308_bases
ATGACACCGTTTGATATCGGCCTAATCGTTCTGGCCGCGATGCTGGTCCTTGTTTTGCTGGGGATGACCGTCTCCATCGC
GCTGATGGCGTGCTCGTTCGTGGGCGTCTGGCTGATCCGGGGATCGCCGGACCTGGCGGCAAACCTTATGGCGCTGGCGG
CGTCCGACACGATCTCCAGCTACTTCTTTGGCGTGGTGCCATTGTTCGTGCTGATGGGATTCCTCGTCTCGGAATCCGGC
ATGGGGCGCGACGCGTTTGATGTGGCCAACCAGATGTTCCGGCGCATTCGAGGCGGTCTCGGCGTCGGCACCGTGGGGGC
CAACGCGATCTTTGCCGCGATCACGGGCGTGTCTATCGCGTCAGCCGCCGTCTTCACGAAGATCGCCGTGCCACAGATGA
TGCGCAACGGCTATTCTCCGCGCTTTGCCACGGGCGTTGTGGCAGGGTCATCGGTGCTCGGGATGCTGATCCCGCCGTCG
CTGCTGCTGATCCTCTACGGTATCCTGACAGAGCAAAACATCGGCGATTTGTTTATCGCGGGCATCGGGCCGGGCATCCT
GCTGGCGCTGGCATTCGGCATCGGCATCGTCGTGACAGCCATCTTCGCGCCGCGGACGTTGGGCAACCCCCAGATCCCGG
AGGAGGGCGAAATCTCCCGCGCGAATCTGCTCAGGAAGGGCCTGCCGATTGTGGCCCTGATCGTGCTGGTTCTGGGCGGG
ATCTATGGCGGCATCTTCACGCCCGTGGAGGCGGGTGGCATCGGCGCGCTTGGCGCACTGGCGTTGGGCATCATGAAGCG
CACGCTCGGCTTGCGTGCATTGGGCCGGGTGCTGGTCGACACGGGGCTGGTGACGGCGGCGATCTGTTTTCTGATCATCG
CCGCCCAGATGTATTCGCGGATGCTGGCGCTGTCAGGTCTTCCGGCAGGCTTTGGGGCCTTCGTGATTGACGCAGAGCTG
GGTCTGACAATGGTCCTGCTCCTTTACATCCTTGTCGTCATTGCCATGGGCATGATGCTCGACAGCTCATCCATCATGCT
GATCCTGGTGCCGTTGATGATGCCTGTCATGGTGGGGTTTGACGTCGATCTGATCTGGTTCGGGATCGTCACGGTCATCG
CCGTGGAAATCGGACTGCTGACCCCGCCGTTCGGGATATCAGTCTACGTCATCAAATCCACACTGGATGATCCCTTCATC
ACCCTTGGCGACATCTTCATCGGTGCGGCCCCCTTCGCGCTGGCCATGCTGGCGGTGTTGATGCTGGTCGTCGCCTTCCC
GGTCATAGCCACCGGATTAATCCCCTGA

Upstream 100 bases:

>100_bases
GGCCGATGAAGGCAACAATTGTCGTCGGCGGCGCGCTTTTGGTGCTGCAATTCGCCGGACGGATCTGGCGACGCCACCTT
GCGCGGCACGGAGCCCTCGC

Downstream 100 bases:

>100_bases
AAGGAGCCGTCATGCCGCGCAGATTTATTGATATTTCGGTCGCGCTGGAGGCAGGCATCGCGTCTGATCCGCCGATCATG
TTGCCGCAGATTGACTACTT

Product: TRAP C4-dicarboxylate transport system permease DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTPFDIGLIVLAAMLVLVLLGMTVSIALMACSFVGVWLIRGSPDLAANLMALAASDTISSYFFGVVPLFVLMGFLVSESG
MGRDAFDVANQMFRRIRGGLGVGTVGANAIFAAITGVSIASAAVFTKIAVPQMMRNGYSPRFATGVVAGSSVLGMLIPPS
LLLILYGILTEQNIGDLFIAGIGPGILLALAFGIGIVVTAIFAPRTLGNPQIPEEGEISRANLLRKGLPIVALIVLVLGG
IYGGIFTPVEAGGIGALGALALGIMKRTLGLRALGRVLVDTGLVTAAICFLIIAAQMYSRMLALSGLPAGFGAFVIDAEL
GLTMVLLLYILVVIAMGMMLDSSSIMLILVPLMMPVMVGFDVDLIWFGIVTVIAVEIGLLTPPFGISVYVIKSTLDDPFI
TLGDIFIGAAPFALAMLAVLMLVVAFPVIATGLIP

Sequences:

>Translated_435_residues
MTPFDIGLIVLAAMLVLVLLGMTVSIALMACSFVGVWLIRGSPDLAANLMALAASDTISSYFFGVVPLFVLMGFLVSESG
MGRDAFDVANQMFRRIRGGLGVGTVGANAIFAAITGVSIASAAVFTKIAVPQMMRNGYSPRFATGVVAGSSVLGMLIPPS
LLLILYGILTEQNIGDLFIAGIGPGILLALAFGIGIVVTAIFAPRTLGNPQIPEEGEISRANLLRKGLPIVALIVLVLGG
IYGGIFTPVEAGGIGALGALALGIMKRTLGLRALGRVLVDTGLVTAAICFLIIAAQMYSRMLALSGLPAGFGAFVIDAEL
GLTMVLLLYILVVIAMGMMLDSSSIMLILVPLMMPVMVGFDVDLIWFGIVTVIAVEIGLLTPPFGISVYVIKSTLDDPFI
TLGDIFIGAAPFALAMLAVLMLVVAFPVIATGLIP
>Mature_434_residues
TPFDIGLIVLAAMLVLVLLGMTVSIALMACSFVGVWLIRGSPDLAANLMALAASDTISSYFFGVVPLFVLMGFLVSESGM
GRDAFDVANQMFRRIRGGLGVGTVGANAIFAAITGVSIASAAVFTKIAVPQMMRNGYSPRFATGVVAGSSVLGMLIPPSL
LLILYGILTEQNIGDLFIAGIGPGILLALAFGIGIVVTAIFAPRTLGNPQIPEEGEISRANLLRKGLPIVALIVLVLGGI
YGGIFTPVEAGGIGALGALALGIMKRTLGLRALGRVLVDTGLVTAAICFLIIAAQMYSRMLALSGLPAGFGAFVIDAELG
LTMVLLLYILVVIAMGMMLDSSSIMLILVPLMMPVMVGFDVDLIWFGIVTVIAVEIGLLTPPFGISVYVIKSTLDDPFIT
LGDIFIGAAPFALAMLAVLMLVVAFPVIATGLIP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=398, Percent_Identity=28.643216080402, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45081; Mature: 44949

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFDIGLIVLAAMLVLVLLGMTVSIALMACSFVGVWLIRGSPDLAANLMALAASDTISS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
YFFGVVPLFVLMGFLVSESGMGRDAFDVANQMFRRIRGGLGVGTVGANAIFAAITGVSIA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SAAVFTKIAVPQMMRNGYSPRFATGVVAGSSVLGMLIPPSLLLILYGILTEQNIGDLFIA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEE
GIGPGILLALAFGIGIVVTAIFAPRTLGNPQIPEEGEISRANLLRKGLPIVALIVLVLGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
IYGGIFTPVEAGGIGALGALALGIMKRTLGLRALGRVLVDTGLVTAAICFLIIAAQMYSR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLALSGLPAGFGAFVIDAELGLTMVLLLYILVVIAMGMMLDSSSIMLILVPLMMPVMVGF
HHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
DVDLIWFGIVTVIAVEIGLLTPPFGISVYVIKSTLDDPFITLGDIFIGAAPFALAMLAVL
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
MLVVAFPVIATGLIP
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPFDIGLIVLAAMLVLVLLGMTVSIALMACSFVGVWLIRGSPDLAANLMALAASDTISS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHH
YFFGVVPLFVLMGFLVSESGMGRDAFDVANQMFRRIRGGLGVGTVGANAIFAAITGVSIA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SAAVFTKIAVPQMMRNGYSPRFATGVVAGSSVLGMLIPPSLLLILYGILTEQNIGDLFIA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEE
GIGPGILLALAFGIGIVVTAIFAPRTLGNPQIPEEGEISRANLLRKGLPIVALIVLVLGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
IYGGIFTPVEAGGIGALGALALGIMKRTLGLRALGRVLVDTGLVTAAICFLIIAAQMYSR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLALSGLPAGFGAFVIDAELGLTMVLLLYILVVIAMGMMLDSSSIMLILVPLMMPVMVGF
HHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
DVDLIWFGIVTVIAVEIGLLTPPFGISVYVIKSTLDDPFITLGDIFIGAAPFALAMLAVL
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
MLVVAFPVIATGLIP
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]