Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 89054505

GI number: 89054505

Start: 2020086

End: 2020805

Strand: Reverse

Name: ompR [H]

Synonym: Jann_2014

Alternate gene names: 89054505

Gene position: 2020805-2020086 (Counterclockwise)

Preceding gene: 89054506

Following gene: 89054504

Centisome position: 46.8

GC content: 60.28

Gene sequence:

>720_bases
ATGACAGACGCCATACTGCTGGTCGAAGATGACACACGCCTCGCCGAGATGGTCGCAAGCTATCTCGGCGGGAACGGTTT
TGATGTGTCCCGTGTGGATACCGGCGAAAAGGCATTGGGCCTTCAGGGGCGCCAGAGTTTCGAGGCGATGATACTGGATC
TCAATCTGCCGGGTATCGACGGCCTGGAAGTCTGTCGCCATGTCAAAGCCCAAAGCGCGCTGCCGATCATAATGCTCACG
GCCAAAGGCGACCCGATGGACCGGATCATCGGGTTGGAAATCGGGGCCGATGACTATCTGCCGAAGCCTTTCGAGCCGCG
CGAACTGCTGGCGCGTTTGCGGGCCGTCATGCGTCGCGGCCAAACGTCCCCGCATGCAGGTTCAACTCCCCTCCAGTTTG
GCCGATTACAGATCGACCCGGGCGCCATGGTTGCGCGTGTGGATGGTCGACCCTGCGATCTGACCACCCATCAATTTCAA
ATCCTGCTGGTGCTGGCCCGGGCGGCGGGTCGCGTCCTGAGCCGTGATGCGTTGATGGACGCATTGAGAGGGGAAGCGCT
TGAGGCCTTCGATCGTTCCATTGATGTACATGTTTCCCGCATCCGGGCGGAGATCGAGGACGACCCCAAACACCCACGGC
GGATCATCACGGTCCGCGGCGCGGGCTATGTTTTTGCCCGTATTCACGATGGCGATAAACACGTCAGGGACCGCGTATGA

Upstream 100 bases:

>100_bases
CGCCGAGCAGCGCCAAACAGCGGCCGAGCGGATAGAATTCTTCCGCGAAATGCGCGAACGTCGCCGCGGTGAAGACTGAC
CCTCGCTGCAAGGAGACCCG

Downstream 100 bases:

>100_bases
TCCGCCAGCGCCTCTTTCTGCAAATCTACCTGACGATCATCGCAGCGCTTACCTTGACGGTCCTGACCACGTCCTTCGCG
TTCTCTCGTCTCGGGCCAGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTDAILLVEDDTRLAEMVASYLGGNGFDVSRVDTGEKALGLQGRQSFEAMILDLNLPGIDGLEVCRHVKAQSALPIIMLT
AKGDPMDRIIGLEIGADDYLPKPFEPRELLARLRAVMRRGQTSPHAGSTPLQFGRLQIDPGAMVARVDGRPCDLTTHQFQ
ILLVLARAAGRVLSRDALMDALRGEALEAFDRSIDVHVSRIRAEIEDDPKHPRRIITVRGAGYVFARIHDGDKHVRDRV

Sequences:

>Translated_239_residues
MTDAILLVEDDTRLAEMVASYLGGNGFDVSRVDTGEKALGLQGRQSFEAMILDLNLPGIDGLEVCRHVKAQSALPIIMLT
AKGDPMDRIIGLEIGADDYLPKPFEPRELLARLRAVMRRGQTSPHAGSTPLQFGRLQIDPGAMVARVDGRPCDLTTHQFQ
ILLVLARAAGRVLSRDALMDALRGEALEAFDRSIDVHVSRIRAEIEDDPKHPRRIITVRGAGYVFARIHDGDKHVRDRV
>Mature_238_residues
TDAILLVEDDTRLAEMVASYLGGNGFDVSRVDTGEKALGLQGRQSFEAMILDLNLPGIDGLEVCRHVKAQSALPIIMLTA
KGDPMDRIIGLEIGADDYLPKPFEPRELLARLRAVMRRGQTSPHAGSTPLQFGRLQIDPGAMVARVDGRPCDLTTHQFQI
LLVLARAAGRVLSRDALMDALRGEALEAFDRSIDVHVSRIRAEIEDDPKHPRRIITVRGAGYVFARIHDGDKHVRDRV

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=47.8632478632479, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.5545851528384, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.0530973451327, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.6812227074236, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=35.2678571428571, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=35.1931330472103, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.2678571428571, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.7586206896552, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=36.7713004484305, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.2222222222222, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.034632034632, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.920704845815, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=29.6296296296296, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=140, Percent_Identity=27.8571428571429, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26348; Mature: 26217

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAILLVEDDTRLAEMVASYLGGNGFDVSRVDTGEKALGLQGRQSFEAMILDLNLPGID
CCCEEEEEECCHHHHHHHHHHHCCCCCEECCCCCCCHHHCCCCCCCEEEEEEEECCCCCC
GLEVCRHVKAQSALPIIMLTAKGDPMDRIIGLEIGADDYLPKPFEPRELLARLRAVMRRG
HHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
QTSPHAGSTPLQFGRLQIDPGAMVARVDGRPCDLTTHQFQILLVLARAAGRVLSRDALMD
CCCCCCCCCCCEECEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALRGEALEAFDRSIDVHVSRIRAEIEDDPKHPRRIITVRGAGYVFARIHDGDKHVRDRV
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCHHHHCCC
>Mature Secondary Structure 
TDAILLVEDDTRLAEMVASYLGGNGFDVSRVDTGEKALGLQGRQSFEAMILDLNLPGID
CCEEEEEECCHHHHHHHHHHHCCCCCEECCCCCCCHHHCCCCCCCEEEEEEEECCCCCC
GLEVCRHVKAQSALPIIMLTAKGDPMDRIIGLEIGADDYLPKPFEPRELLARLRAVMRRG
HHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
QTSPHAGSTPLQFGRLQIDPGAMVARVDGRPCDLTTHQFQILLVLARAAGRVLSRDALMD
CCCCCCCCCCCEECEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALRGEALEAFDRSIDVHVSRIRAEIEDDPKHPRRIITVRGAGYVFARIHDGDKHVRDRV
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]