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The map label for this gene is rstB [H]

Identifier: 89054504

GI number: 89054504

Start: 2018857

End: 2020089

Strand: Reverse

Name: rstB [H]

Synonym: Jann_2013

Alternate gene names: 89054504

Gene position: 2020089-2018857 (Counterclockwise)

Preceding gene: 89054505

Following gene: 89054503

Centisome position: 46.78

GC content: 61.88

Gene sequence:

>1233_bases
ATGATCCGCCAGCGCCTCTTTCTGCAAATCTACCTGACGATCATCGCAGCGCTTACCTTGACGGTCCTGACCACGTCCTT
CGCGTTCTCTCGTCTCGGGCCAGAGGAACGACCCAGTGCGACTGCCATCACCTTGGCTCAACGTGCCGTCGCCCAGGCAT
TGCCTCCCGCCGGTGCTCCGGTCAGCCAACAGGCCTCGGCCCTGGAGCTGGTCCGCGCGGATTTGAGCATCGAGTTGGCG
TTGTTTGATGCGCAAGGCGCGCTCATCACTGCACGGCCAATGCCCGAGACAAGCGATTGGACCGTCGAAGACCTCAACTG
GCACGACGGTCCGGAAAGTCTGCTGACCCTGCCGGATGGCCGGATGGTCGCGGCCCGCGTCCCTTTTCCCGGCTTGGGCG
GCGTTGGTGCGCTCGTGCTTGTGCTGAGTTCAATCGCACTGGCCGTAGCAGTTGCGTCCTACCCGCTGGTGCGTCGGTTG
ACGGGACGCCTGGAGGGGCTGAAGGTTGCTGTTGAGCGCATTGGAGATGGTAATCTGTCGACGCGGGCGCACATCGAGGG
GCGCGACGAAATTGCCGCCTTGGCCCACAGCTTCAATGATGCCGCCGACAGGATCGAAGCGTTGGTCGATGCACATCGTG
TTCTTCTCGCCAATGCCTCCCACGAACTAAGGACCCCTTTGTCGCGCATCCGCCTCGGGTTGGAGATGTTTCGCGAGACG
GGGGAGGCCCATCGCCTTGCACATGTGGAAACCGATATCGGGCAACTCGATAGCCTGATCGACGAGATCCTGACCCTAAG
CCGCCTGGACGCTGCACCCATCGAAATGGAACCCGACATCGACCTTTTGGGTCTGGTGGCAGAGGAGTGTGCAGATGCAG
ACGTGTCCGTCGCAGGCCAACCCGCCCTTATCCGTGGCAATCGCGAACTACTGCGCCGCCTCGTGCGCAACCTCGTCACG
AACGCCGAGCGTCACGGCGCGCCGCCGATCGAGGTTGAGGTGATGCCGCACGCGGCGAAGACGACGCTATCGGTGCGCGA
TGCAGGCAAAGGCTTTGCGACTGACGACCGCGAAAAAGTGTTCGAACGTTTCTACCGGGGTCGTAACAAGCAAAACGTCG
AGGGATACGGCTTGGGCCTGCCGCTTGTGCAGCAGATCGCGCAAGCGCATGGCGGACGGGTGAACATTTCAGAAAATGAG
GGCAGCGCGATCACCGTGACTTTCGCGCAGTAG

Upstream 100 bases:

>100_bases
AGGACGACCCCAAACACCCACGGCGGATCATCACGGTCCGCGGCGCGGGCTATGTTTTTGCCCGTATTCACGATGGCGAT
AAACACGTCAGGGACCGCGT

Downstream 100 bases:

>100_bases
GGACTGTGCGCCGAAACGCCTGATCGGCGGGGCACTGCTGACGATCGCTGCGTTCTCGGCGAGGCTCACTTGTAGCAGAA
CGTTTATTCTGCTACGCATC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MIRQRLFLQIYLTIIAALTLTVLTTSFAFSRLGPEERPSATAITLAQRAVAQALPPAGAPVSQQASALELVRADLSIELA
LFDAQGALITARPMPETSDWTVEDLNWHDGPESLLTLPDGRMVAARVPFPGLGGVGALVLVLSSIALAVAVASYPLVRRL
TGRLEGLKVAVERIGDGNLSTRAHIEGRDEIAALAHSFNDAADRIEALVDAHRVLLANASHELRTPLSRIRLGLEMFRET
GEAHRLAHVETDIGQLDSLIDEILTLSRLDAAPIEMEPDIDLLGLVAEECADADVSVAGQPALIRGNRELLRRLVRNLVT
NAERHGAPPIEVEVMPHAAKTTLSVRDAGKGFATDDREKVFERFYRGRNKQNVEGYGLGLPLVQQIAQAHGGRVNISENE
GSAITVTFAQ

Sequences:

>Translated_410_residues
MIRQRLFLQIYLTIIAALTLTVLTTSFAFSRLGPEERPSATAITLAQRAVAQALPPAGAPVSQQASALELVRADLSIELA
LFDAQGALITARPMPETSDWTVEDLNWHDGPESLLTLPDGRMVAARVPFPGLGGVGALVLVLSSIALAVAVASYPLVRRL
TGRLEGLKVAVERIGDGNLSTRAHIEGRDEIAALAHSFNDAADRIEALVDAHRVLLANASHELRTPLSRIRLGLEMFRET
GEAHRLAHVETDIGQLDSLIDEILTLSRLDAAPIEMEPDIDLLGLVAEECADADVSVAGQPALIRGNRELLRRLVRNLVT
NAERHGAPPIEVEVMPHAAKTTLSVRDAGKGFATDDREKVFERFYRGRNKQNVEGYGLGLPLVQQIAQAHGGRVNISENE
GSAITVTFAQ
>Mature_410_residues
MIRQRLFLQIYLTIIAALTLTVLTTSFAFSRLGPEERPSATAITLAQRAVAQALPPAGAPVSQQASALELVRADLSIELA
LFDAQGALITARPMPETSDWTVEDLNWHDGPESLLTLPDGRMVAARVPFPGLGGVGALVLVLSSIALAVAVASYPLVRRL
TGRLEGLKVAVERIGDGNLSTRAHIEGRDEIAALAHSFNDAADRIEALVDAHRVLLANASHELRTPLSRIRLGLEMFRET
GEAHRLAHVETDIGQLDSLIDEILTLSRLDAAPIEMEPDIDLLGLVAEECADADVSVAGQPALIRGNRELLRRLVRNLVT
NAERHGAPPIEVEVMPHAAKTTLSVRDAGKGFATDDREKVFERFYRGRNKQNVEGYGLGLPLVQQIAQAHGGRVNISENE
GSAITVTFAQ

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=441, Percent_Identity=28.1179138321995, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=32.7868852459016, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789808, Length=274, Percent_Identity=28.4671532846715, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=31.140350877193, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=30.2631578947368, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=319, Percent_Identity=25.3918495297806, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=27.3092369477912, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=23.3108108108108, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=228, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=24.1803278688525, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44232; Mature: 44232

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQRLFLQIYLTIIAALTLTVLTTSFAFSRLGPEERPSATAITLAQRAVAQALPPAGAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VSQQASALELVRADLSIELALFDAQGALITARPMPETSDWTVEDLNWHDGPESLLTLPDG
CHHHHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCCCCCEEECCCCCCCCHHEEECCCC
RMVAARVPFPGLGGVGALVLVLSSIALAVAVASYPLVRRLTGRLEGLKVAVERIGDGNLS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TRAHIEGRDEIAALAHSFNDAADRIEALVDAHRVLLANASHELRTPLSRIRLGLEMFRET
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHC
GEAHRLAHVETDIGQLDSLIDEILTLSRLDAAPIEMEPDIDLLGLVAEECADADVSVAGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCC
PALIRGNRELLRRLVRNLVTNAERHGAPPIEVEVMPHAAKTTLSVRDAGKGFATDDREKV
CEEEECCHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCHHHEEEHHHCCCCCCCCHHHHH
FERFYRGRNKQNVEGYGLGLPLVQQIAQAHGGRVNISENEGSAITVTFAQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MIRQRLFLQIYLTIIAALTLTVLTTSFAFSRLGPEERPSATAITLAQRAVAQALPPAGAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VSQQASALELVRADLSIELALFDAQGALITARPMPETSDWTVEDLNWHDGPESLLTLPDG
CHHHHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCCCCCEEECCCCCCCCHHEEECCCC
RMVAARVPFPGLGGVGALVLVLSSIALAVAVASYPLVRRLTGRLEGLKVAVERIGDGNLS
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TRAHIEGRDEIAALAHSFNDAADRIEALVDAHRVLLANASHELRTPLSRIRLGLEMFRET
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHC
GEAHRLAHVETDIGQLDSLIDEILTLSRLDAAPIEMEPDIDLLGLVAEECADADVSVAGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCC
PALIRGNRELLRRLVRNLVTNAERHGAPPIEVEVMPHAAKTTLSVRDAGKGFATDDREKV
CEEEECCHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCHHHEEEHHHCCCCCCCCHHHHH
FERFYRGRNKQNVEGYGLGLPLVQQIAQAHGGRVNISENEGSAITVTFAQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]