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The map label for this gene is fur [H]

Identifier: 89054290

GI number: 89054290

Start: 1788579

End: 1788992

Strand: Reverse

Name: fur [H]

Synonym: Jann_1799

Alternate gene names: 89054290

Gene position: 1788992-1788579 (Counterclockwise)

Preceding gene: 89054291

Following gene: 89054289

Centisome position: 41.43

GC content: 60.14

Gene sequence:

>414_bases
ATGACCGACACAATCGAGGATCGCTGCACAGCCAAGGGCCTGCGCATGACCGAGCAACGCCGCGTGATCGCGCGTGTGCT
GGAACGCTCGGACGATCATCCGGACGTGGAAGAGCTTTATGCCCGTGCGGTGGCGGTCGACCCCAAGATCTCCATTGCGA
CGGTCTACCGGACGGTGAAGCTGTTTGAGGAGGCAGGCATCCTCGACAAGCTGGAATTCGGCGATGGCCGCGCGCGCTAT
GAGGATGCGGAGCGGGACCACCATGATCACCTGATCGATATGAATTCAGGCGAGGTGATCGAGTTCGTCGACGCTGAGAT
TGAGGCCTTGCAGGAGAGGATTGCCGAGAAGCTGGGATATCGGCTGAAGGGGCATCGGTTGGAGTTGTACGGCGTGCCCT
TGAAGAAGGGGTGA

Upstream 100 bases:

>100_bases
GGCTGCCATCCCGCGCGGGCTTTATCCGCGCGGGCAAATCCCCTAGACCCCGCCCTGACATCGCTTCCCCCTTCCCCCGT
ATTCCGTGCGAGGCCCCACC

Downstream 100 bases:

>100_bases
GCGTTGTTGCGAGAGAATTTGCGCCGCCTGCGGCACCAGGACGTTGCACGGACTGCGCTGACCGCGGCATCGGGATTCTC
TGGGGGTTGCGCTGCCTGCG

Product: FUR family manganese uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTDTIEDRCTAKGLRMTEQRRVIARVLERSDDHPDVEELYARAVAVDPKISIATVYRTVKLFEEAGILDKLEFGDGRARY
EDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIAEKLGYRLKGHRLELYGVPLKKG

Sequences:

>Translated_137_residues
MTDTIEDRCTAKGLRMTEQRRVIARVLERSDDHPDVEELYARAVAVDPKISIATVYRTVKLFEEAGILDKLEFGDGRARY
EDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIAEKLGYRLKGHRLELYGVPLKKG
>Mature_136_residues
TDTIEDRCTAKGLRMTEQRRVIARVLERSDDHPDVEELYARAVAVDPKISIATVYRTVKLFEEAGILDKLEFGDGRARYE
DAERDHHDHLIDMNSGEVIEFVDAEIEALQERIAEKLGYRLKGHRLELYGVPLKKG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=44.1666666666667, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15738; Mature: 15607

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTIEDRCTAKGLRMTEQRRVIARVLERSDDHPDVEELYARAVAVDPKISIATVYRTVK
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
LFEEAGILDKLEFGDGRARYEDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIAEKLGY
HHHHCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCC
RLKGHRLELYGVPLKKG
CCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TDTIEDRCTAKGLRMTEQRRVIARVLERSDDHPDVEELYARAVAVDPKISIATVYRTVK
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
LFEEAGILDKLEFGDGRARYEDAERDHHDHLIDMNSGEVIEFVDAEIEALQERIAEKLGY
HHHHCCCCCEECCCCCCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHCC
RLKGHRLELYGVPLKKG
CCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]