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The map label for this gene is 89054216

Identifier: 89054216

GI number: 89054216

Start: 1715069

End: 1715779

Strand: Reverse

Name: 89054216

Synonym: Jann_1725

Alternate gene names: NA

Gene position: 1715779-1715069 (Counterclockwise)

Preceding gene: 89054217

Following gene: 89054215

Centisome position: 39.74

GC content: 65.96

Gene sequence:

>711_bases
ATGGGCAATTCCATCGCCTTCACCCTGCGCGGCCCGTGGCGCATCCCGATCCAGTTCGACATCAGCCTGCTGATCCTCGC
CGTGCTGTTTGGCATGATCTTCATCGACCGAGGCATCCTTGCGGCGGCCACGGCCTTTGCGATGATCGTCATCGCCATCC
TCCTGCACGAATTGGGCCACGCCGCCGCCTGCGTCGTCCAGCGCGTGCCCGTGACCCGCGTCGTGCTGTTTGGCGGCGGC
GGGTTTTGCGAACACGACGCCCGCGTCACCCCGCGCCAGGCGGAACTGATCGCCATCGCGGGCCCCCTGGTGAACCTCGC
GCTCTGGGCCGTTGCCACGCTTGTCCTGCCTGCGCTGGCCGCTGGCCCGCCCGAGCCGATCAACGTCAACGGCACATGGA
TCACCGGCCCACCGCTCGGGCAGTCCGACCTCTACCGCACGCTGGAGATCTTCGCCCGGCTCAACCTGTTTCTCGCCCTG
TTCAACCTGATCCCGGTCCTGCCGCTGGATGGGGGGCGGCTCCTGCATTCCTGGCTGCACCGCTTCGTCAACGGCGCGAC
TGCCAATCGGATCACCGGCGGCGTGGGGGTCGTGCTGTCGATCCTCTGGATCCCGTTGATGTTTGCCGCCTTTTTCACCT
TCGGCTTCATCCTGATCTTCTTCCCCAACCTGGTCCTGCACTGGCGAATGTTGCGACACGGCCAGGGGTGA

Upstream 100 bases:

>100_bases
TGCCCAAACCTGACCCTCACCGCGCCACCACGCTACGCCGACATCTATCATTTTCACGGGCTCGACGCCCTCATGGTGCA
GGCGTGAAAGGGCGGTGCTG

Downstream 100 bases:

>100_bases
CGATCCGCGCCGGGCCGGAATGTCCTGAAAAATTTGGGTCACGACGCGCAGGTTTCCGCCGAGATCGGCAGGCGCGGGGT
ACGGGATGCCTGCCTTGGCG

Product: peptidase M50

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MGNSIAFTLRGPWRIPIQFDISLLILAVLFGMIFIDRGILAAATAFAMIVIAILLHELGHAAACVVQRVPVTRVVLFGGG
GFCEHDARVTPRQAELIAIAGPLVNLALWAVATLVLPALAAGPPEPINVNGTWITGPPLGQSDLYRTLEIFARLNLFLAL
FNLIPVLPLDGGRLLHSWLHRFVNGATANRITGGVGVVLSILWIPLMFAAFFTFGFILIFFPNLVLHWRMLRHGQG

Sequences:

>Translated_236_residues
MGNSIAFTLRGPWRIPIQFDISLLILAVLFGMIFIDRGILAAATAFAMIVIAILLHELGHAAACVVQRVPVTRVVLFGGG
GFCEHDARVTPRQAELIAIAGPLVNLALWAVATLVLPALAAGPPEPINVNGTWITGPPLGQSDLYRTLEIFARLNLFLAL
FNLIPVLPLDGGRLLHSWLHRFVNGATANRITGGVGVVLSILWIPLMFAAFFTFGFILIFFPNLVLHWRMLRHGQG
>Mature_235_residues
GNSIAFTLRGPWRIPIQFDISLLILAVLFGMIFIDRGILAAATAFAMIVIAILLHELGHAAACVVQRVPVTRVVLFGGGG
FCEHDARVTPRQAELIAIAGPLVNLALWAVATLVLPALAAGPPEPINVNGTWITGPPLGQSDLYRTLEIFARLNLFLALF
NLIPVLPLDGGRLLHSWLHRFVNGATANRITGGVGVVLSILWIPLMFAAFFTFGFILIFFPNLVLHWRMLRHGQG

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 25641; Mature: 25510

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSIAFTLRGPWRIPIQFDISLLILAVLFGMIFIDRGILAAATAFAMIVIAILLHELGH
CCCCEEEEEECCEEEEHEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AAACVVQRVPVTRVVLFGGGGFCEHDARVTPRQAELIAIAGPLVNLALWAVATLVLPALA
HHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHH
AGPPEPINVNGTWITGPPLGQSDLYRTLEIFARLNLFLALFNLIPVLPLDGGRLLHSWLH
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFVNGATANRITGGVGVVLSILWIPLMFAAFFTFGFILIFFPNLVLHWRMLRHGQG
HHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GNSIAFTLRGPWRIPIQFDISLLILAVLFGMIFIDRGILAAATAFAMIVIAILLHELGH
CCCEEEEEECCEEEEHEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AAACVVQRVPVTRVVLFGGGGFCEHDARVTPRQAELIAIAGPLVNLALWAVATLVLPALA
HHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHH
AGPPEPINVNGTWITGPPLGQSDLYRTLEIFARLNLFLALFNLIPVLPLDGGRLLHSWLH
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFVNGATANRITGGVGVVLSILWIPLMFAAFFTFGFILIFFPNLVLHWRMLRHGQG
HHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]