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The map label for this gene is bioI [H]

Identifier: 89054217

GI number: 89054217

Start: 1715793

End: 1716956

Strand: Reverse

Name: bioI [H]

Synonym: Jann_1726

Alternate gene names: 89054217

Gene position: 1716956-1715793 (Counterclockwise)

Preceding gene: 89054218

Following gene: 89054216

Centisome position: 39.76

GC content: 65.89

Gene sequence:

>1164_bases
ATGATCACGCTGCACCAATCGCCCACGGACGACGATTTCGTCCAGAACCCCTACCCGTTCTACGCGGCGGCGCGCGCTCA
CGGCCCGCTGGTCCACTGGGCCGATTACGCGATGCCCTGCACGACCACCTTTGCTGCCACCAACGCGATTCTGCGCGACC
GCCGGTTTGGGCGCGAGCCCGTCGATGCGCTGCCTGTTCCCGACCATCTCCAGCCGTTCTACGATGTCGAAGCCCATTCC
ATGCTGGAGCTGGAGCCACCGCGCCACACCCGCCTGCGCGGCCTTGTCCTGCGTGCCTTCACCAACCGGCGGATCAAGGC
GCTGGCCCCTGACATCACCCAGCTGACCCATGATCTGATCGACGCCTTTCCGGACGGCGCGCATGATCTGCTAGACACAT
TCGCCCGCCCCCTGCCCGTCACCCTCATCGCCCGCCTTCTGGGCGTGCCCGAGGAGATGGCGCCGGACCTCCTGCGCTGG
TCCAACGCCATGGTGATGATGTATCAGGCGGGCCGAACCCGCAGCGACGAGGACGTCGCCGTCAAGGCGACGGAGGAGTT
CGTGGCCTTCATGCGAGACTATGCCCGGCAGCGTCGCAAAGACCCCCGCGACGACCTGATCACCGCCCTGATCGCCGCAG
AAGAAGACGGCGAAAAGCTCTCCACCGATGAGCTGATCACCACCTGCATCCTGCTGCTGAACGCGGGCCATGAGGCGACG
GTCCATTCCATCGGCAACGGCGTGAAACTCTGCCTCCAACAGCAGCACCGCCCGCCACGGGACCCGGCCAAGTTCACCGA
AGAACTCCTGCGCATCGACCCGCCGCTGCACATGTTCACGCGCACCGCCTATGAAGATGTCACGCTCCACGGCCACACGT
TCCAGCGCGGCGATCAGGTGGCGCTTCTCCTTGCCGCCGCCAACCGTGATCCCGCTGCCTACCCCGATCCCGATACCTTC
GACCCCGCCCGCAAAGGCCCCGCGCAACTGGCCTTCGGCGCGGGTCTGCATTTCTGCGTCGGCGCGCCCCTGGCCCGGCT
AGAGCTGCAAATCGCCCTGCCGATCCTCTTTGATCGCTGCCCAAACCTGACCCTCACCGCGCCACCACGCTACGCCGACA
TCTATCATTTTCACGGGCTCGACGCCCTCATGGTGCAGGCGTGA

Upstream 100 bases:

>100_bases
CGTCCATTCCGGTGCGCGGGGCAGATTAACCCCGCCCACATGTGAAAAAACCTCCGACGCCCCCTACCCAGCGGGGCGTC
GATCTACTTTAACGGCCCCC

Downstream 100 bases:

>100_bases
AAGGGCGGTGCTGATGGGCAATTCCATCGCCTTCACCCTGCGCGGCCCGTGGCGCATCCCGATCCAGTTCGACATCAGCC
TGCTGATCCTCGCCGTGCTG

Product: cytochrome P450

Products: ROH; oxidized flavoprotein; H2O

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MITLHQSPTDDDFVQNPYPFYAAARAHGPLVHWADYAMPCTTTFAATNAILRDRRFGREPVDALPVPDHLQPFYDVEAHS
MLELEPPRHTRLRGLVLRAFTNRRIKALAPDITQLTHDLIDAFPDGAHDLLDTFARPLPVTLIARLLGVPEEMAPDLLRW
SNAMVMMYQAGRTRSDEDVAVKATEEFVAFMRDYARQRRKDPRDDLITALIAAEEDGEKLSTDELITTCILLLNAGHEAT
VHSIGNGVKLCLQQQHRPPRDPAKFTEELLRIDPPLHMFTRTAYEDVTLHGHTFQRGDQVALLLAAANRDPAAYPDPDTF
DPARKGPAQLAFGAGLHFCVGAPLARLELQIALPILFDRCPNLTLTAPPRYADIYHFHGLDALMVQA

Sequences:

>Translated_387_residues
MITLHQSPTDDDFVQNPYPFYAAARAHGPLVHWADYAMPCTTTFAATNAILRDRRFGREPVDALPVPDHLQPFYDVEAHS
MLELEPPRHTRLRGLVLRAFTNRRIKALAPDITQLTHDLIDAFPDGAHDLLDTFARPLPVTLIARLLGVPEEMAPDLLRW
SNAMVMMYQAGRTRSDEDVAVKATEEFVAFMRDYARQRRKDPRDDLITALIAAEEDGEKLSTDELITTCILLLNAGHEAT
VHSIGNGVKLCLQQQHRPPRDPAKFTEELLRIDPPLHMFTRTAYEDVTLHGHTFQRGDQVALLLAAANRDPAAYPDPDTF
DPARKGPAQLAFGAGLHFCVGAPLARLELQIALPILFDRCPNLTLTAPPRYADIYHFHGLDALMVQA
>Mature_387_residues
MITLHQSPTDDDFVQNPYPFYAAARAHGPLVHWADYAMPCTTTFAATNAILRDRRFGREPVDALPVPDHLQPFYDVEAHS
MLELEPPRHTRLRGLVLRAFTNRRIKALAPDITQLTHDLIDAFPDGAHDLLDTFARPLPVTLIARLLGVPEEMAPDLLRW
SNAMVMMYQAGRTRSDEDVAVKATEEFVAFMRDYARQRRKDPRDDLITALIAAEEDGEKLSTDELITTCILLLNAGHEAT
VHSIGNGVKLCLQQQHRPPRDPAKFTEELLRIDPPLHMFTRTAYEDVTLHGHTFQRGDQVALLLAAANRDPAAYPDPDTF
DPARKGPAQLAFGAGLHFCVGAPLARLELQIALPILFDRCPNLTLTAPPRYADIYHFHGLDALMVQA

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: 1.14.14.1

Molecular weight: Translated: 43337; Mature: 43337

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLHQSPTDDDFVQNPYPFYAAARAHGPLVHWADYAMPCTTTFAATNAILRDRRFGREP
CEECCCCCCCCHHHCCCCCCEEECCCCCCEEEHHCCCCCCHHHHHHHHHHHHHHHCCCCC
VDALPVPDHLQPFYDVEAHSMLELEPPRHTRLRGLVLRAFTNRRIKALAPDITQLTHDLI
CCCCCCCHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHH
DAFPDGAHDLLDTFARPLPVTLIARLLGVPEEMAPDLLRWSNAMVMMYQAGRTRSDEDVA
HHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
VKATEEFVAFMRDYARQRRKDPRDDLITALIAAEEDGEKLSTDELITTCILLLNAGHEAT
EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHH
VHSIGNGVKLCLQQQHRPPRDPAKFTEELLRIDPPLHMFTRTAYEDVTLHGHTFQRGDQV
HHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCCCCCCCE
ALLLAAANRDPAAYPDPDTFDPARKGPAQLAFGAGLHFCVGAPLARLELQIALPILFDRC
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCHHHEEHEEHHHHHHHCC
PNLTLTAPPRYADIYHFHGLDALMVQA
CCCEEECCCCCCCCHHHCCCCEEEECC
>Mature Secondary Structure
MITLHQSPTDDDFVQNPYPFYAAARAHGPLVHWADYAMPCTTTFAATNAILRDRRFGREP
CEECCCCCCCCHHHCCCCCCEEECCCCCCEEEHHCCCCCCHHHHHHHHHHHHHHHCCCCC
VDALPVPDHLQPFYDVEAHSMLELEPPRHTRLRGLVLRAFTNRRIKALAPDITQLTHDLI
CCCCCCCHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHH
DAFPDGAHDLLDTFARPLPVTLIARLLGVPEEMAPDLLRWSNAMVMMYQAGRTRSDEDVA
HHCCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
VKATEEFVAFMRDYARQRRKDPRDDLITALIAAEEDGEKLSTDELITTCILLLNAGHEAT
EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHH
VHSIGNGVKLCLQQQHRPPRDPAKFTEELLRIDPPLHMFTRTAYEDVTLHGHTFQRGDQV
HHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCEEECCCCCCCCCCE
ALLLAAANRDPAAYPDPDTFDPARKGPAQLAFGAGLHFCVGAPLARLELQIALPILFDRC
EEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCHHHEEHEEHHHHHHHCC
PNLTLTAPPRYADIYHFHGLDALMVQA
CCCEEECCCCCCCCHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RH; reduced flavoprotein; O2

Specific reaction: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]