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The map label for this gene is acr1 [H]

Identifier: 89054194

GI number: 89054194

Start: 1686317

End: 1687048

Strand: Reverse

Name: acr1 [H]

Synonym: Jann_1703

Alternate gene names: 89054194

Gene position: 1687048-1686317 (Counterclockwise)

Preceding gene: 89054197

Following gene: 89054191

Centisome position: 39.07

GC content: 67.76

Gene sequence:

>732_bases
TTGCACTTGCACGTGCAAGGCGGCATCAGGCGGCGACATCGAATTGAGGCGGCGACTGACATGCATTCCGACATCGACCT
TTCCAGTAAGATCGCGCTGGTCACCGGCGCGTCCCGTGGCCTTGGGGCCGCGTCCGCCCTGTGGCTGGCCGAACGCGGGG
CCCATGTGGTGGCCGTGGCGCGCACCATCGGCGGGCTGGAGGATCTGGACGACCGGATCAAGGCGGCAGGCGGGCAAGCC
ACGCTCGCGCCGATGGATCTGACGGATGATGGCGCGGTCGCGCATCTGTGCCGGTCCCTGCATGATCGCTGGGGTCGCGC
CGATATCTGGGTCCACACGGCGATCCATGTCAGCGCCCTGACCCCGGCCCCCCATGTGCAGGCCAAGGACCTCGACAAGG
TCATTGCGACGAACATACGCGGCGTCTCGCGCCTGATCGCCAACACCGAGCCGCTGATCGCGCCGTCCGAGGCCCCTACC
GCCGTGTTCTTCGACGACGATTGGGATGCGAAATTCGCAGGCCCCTACGCGATGTCCAAGGCCGCGCAGCGGGCGCTGGT
GCAAAGCTGGCAGGCCGAGACGGCCAAGGCCCCGATGGCGGTGCATCTTTTGCGCCCGAAGCCGATGCCCACGGCGGTCC
GTGCGCGGTTCTACCCCGGCGAAGACCGCACGCCCCTGGCCGATCCCGCGTCCGAGGCCGATCGCCTTCTGTCGTCTGTC
TTCAATGGCTAG

Upstream 100 bases:

>100_bases
CAGCGTTGCGGAAAGAAGTGTTGCGTTGTGGCCCATGGTGGAGGCTCCCCATTCTTGTCCAGACAGGGCGCAAAGGCCCG
TTGGCGCAAAGGTATACCCC

Downstream 100 bases:

>100_bases
GCGCTGAAGGGCCGAGCGCGCAGCGCGAGGCCCCCGGCGACGCCGTCAGGCGGCGCAATCCCTCAGGCCGTCAGGCTCTA
CCCGCCAGAGGCGCTCCCGG

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MHLHVQGGIRRRHRIEAATDMHSDIDLSSKIALVTGASRGLGAASALWLAERGAHVVAVARTIGGLEDLDDRIKAAGGQA
TLAPMDLTDDGAVAHLCRSLHDRWGRADIWVHTAIHVSALTPAPHVQAKDLDKVIATNIRGVSRLIANTEPLIAPSEAPT
AVFFDDDWDAKFAGPYAMSKAAQRALVQSWQAETAKAPMAVHLLRPKPMPTAVRARFYPGEDRTPLADPASEADRLLSSV
FNG

Sequences:

>Translated_243_residues
MHLHVQGGIRRRHRIEAATDMHSDIDLSSKIALVTGASRGLGAASALWLAERGAHVVAVARTIGGLEDLDDRIKAAGGQA
TLAPMDLTDDGAVAHLCRSLHDRWGRADIWVHTAIHVSALTPAPHVQAKDLDKVIATNIRGVSRLIANTEPLIAPSEAPT
AVFFDDDWDAKFAGPYAMSKAAQRALVQSWQAETAKAPMAVHLLRPKPMPTAVRARFYPGEDRTPLADPASEADRLLSSV
FNG
>Mature_243_residues
MHLHVQGGIRRRHRIEAATDMHSDIDLSSKIALVTGASRGLGAASALWLAERGAHVVAVARTIGGLEDLDDRIKAAGGQA
TLAPMDLTDDGAVAHLCRSLHDRWGRADIWVHTAIHVSALTPAPHVQAKDLDKVIATNIRGVSRLIANTEPLIAPSEAPT
AVFFDDDWDAKFAGPYAMSKAAQRALVQSWQAETAKAPMAVHLLRPKPMPTAVRARFYPGEDRTPLADPASEADRLLSSV
FNG

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26074; Mature: 26074

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLHVQGGIRRRHRIEAATDMHSDIDLSSKIALVTGASRGLGAASALWLAERGAHVVAVA
CEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEHH
RTIGGLEDLDDRIKAAGGQATLAPMDLTDDGAVAHLCRSLHDRWGRADIWVHTAIHVSAL
HHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC
TPAPHVQAKDLDKVIATNIRGVSRLIANTEPLIAPSEAPTAVFFDDDWDAKFAGPYAMSK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
AAQRALVQSWQAETAKAPMAVHLLRPKPMPTAVRARFYPGEDRTPLADPASEADRLLSSV
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
FNG
HCC
>Mature Secondary Structure
MHLHVQGGIRRRHRIEAATDMHSDIDLSSKIALVTGASRGLGAASALWLAERGAHVVAVA
CEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEHH
RTIGGLEDLDDRIKAAGGQATLAPMDLTDDGAVAHLCRSLHDRWGRADIWVHTAIHVSAL
HHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC
TPAPHVQAKDLDKVIATNIRGVSRLIANTEPLIAPSEAPTAVFFDDDWDAKFAGPYAMSK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHH
AAQRALVQSWQAETAKAPMAVHLLRPKPMPTAVRARFYPGEDRTPLADPASEADRLLSSV
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
FNG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA