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The map label for this gene is tktA [H]

Identifier: 89054191

GI number: 89054191

Start: 1682637

End: 1684652

Strand: Reverse

Name: tktA [H]

Synonym: Jann_1700

Alternate gene names: 89054191

Gene position: 1684652-1682637 (Counterclockwise)

Preceding gene: 89054194

Following gene: 89054189

Centisome position: 39.01

GC content: 64.73

Gene sequence:

>2016_bases
ATGGACATCAAAGCCCTTGCAAGCGCCAACCCCGATCACTGGGCCCGTGCCGCCTGCATCCGCACCCTGACGCTGGACGC
CGTGGCCGCCGCCAATTCCGGCCATTCCGGCATGCCGATGGGCATGGCCGATGTGGCGACTGTACTGTTTGACAAACACC
TGAGCTTTGACGCCTCCAACCCCGACTGGCCCAACCGCGACCGCTTCATCCTGTCGGCGGGTCACGGGTCGATGCTGATC
TACAGCCTTCTGCACCTGACCGGTTACAAGGACATGACGCTGGAGCAGATCAAGAATTTCCGCCAATTGGGCGCGATCAC
GGCGGGTCACCCGGAATATGGCCATGTGAAGGGCGTTGAGACGACGACCGGTCCCCTGGGCCAAGGCATTGCCAACGCTG
TGGGTTTCGCCATGGCAGAAGAGCATCTGCGCGCCAAATGGGGCAAGAAGATCATCGACCATTATACCTACTGCATCGCC
GGCGACGGCTGCCTGATGGAAGGGATCAGCCAGGAGGCGCTGGCGCTGGCCGGGCACCAGGAATTGTCGCGGCTGATCGT
CATGTGGGACAACAACAACATCACCATCGACGGCGAGGTCTCCCTATCCGACCGCACGGATCAGATGGCGCGCTTTGCGG
CCAGCGGCTGGGACGTGTTCAGCTGCGACGGCCATGACCCCGCCGACATTGACCGCGCCCTGACCGAGGCCAAGGCGTCC
CCCGGCCCCGCGATGATCGCCTGCAAGACCCACATTGCCATCGGCTCCAGCGCCCAGGATACCGGCAAGGGCCACGGCGC
GCTGACCGATGACAAGCTGATTGCCGACACCAAAGAGGCCTATGGCTGGCCCCATGCGCCGTTTGATATCCCCAAGGATC
TGAAATCCTGGTGGGAAGGTGTGGGGTCCAAAGGGGCCGAGGCGCGCCAGGCCTGGGAAGAGCAATTCGATGCCATGTCC
GCAGGCAAGCGCGCCGAGTTCAACCGCACCTTTGCGGGCGAAATGCCCAAGAAGCTGTCGGCCACGATCAAGGCGTTCAA
GAAACAACTCTCGGACGAGAAGCCCAAGGTCGCGACCCGCAAGGCCAGCCAGATGGCGCTGGAGGTGATCAACACGGTGG
TGCCGGAAACCCTTGGCGGATCAGCGGACCTGACCGGGTCCAACCTGACCAATACCGGCGGTCTGGGGACCTTCGCGCCC
GACGACCGCAAGGGCCGCCACATCCATTACGGCATTCGCGAACACGCCATGGCGGCGGCGATGAATGGGATGATCCTGCA
TGGCGGCGTGAAGCCCTATGGCGGCACCTTCTTCACCTTCACCGACTATGCGCGGCCGTCCATGCGGCTGGCCGCGCTGA
TGAAAATCGCGCCGGTCTATGTGATGACCCACGACAGCATCGGCGTGGGCGAGGATGGCCCGACGCACCAGCCGGTCGAA
CACCTCGCCATGTTGCGCGCCACGCCCAACATGAACGTCTTCCGCCCCGCAGATGCGGTCGAAACGGCGGAGGCGTGGGA
GCTGGCCCTGACATCGACGGACACGCCATCGACCCTCGCCCTGTCGCGTCAGGGGCTGCCGCTTCTGCGCACAGAGCACA
AGACCAAGAACCTCACGGCCCAGGGCGGCTACGTGCTGGCCGATGCGGAGGGCAAGCGCCAGGCGATCCTGATGGCCACG
GGCTCCGAGGTTGCCATCGCCATGGCCGCCCGCGATCTGTTGCAGGCGGAGGGGATCGGCACGCGCGTCGTGTCCCTGCC
CTGCTGGGAATTGTTCGAGGCGCAGGACGAGGCCTACCGCAAGCGGGTCTTGCCCGGTGGCCCGGTCCGCGTCGCCGTGG
AGGCCGCGATCCGCTTCGGCTGGGACCGGTGGCTGTACGGAGAGCGTGGCAAGCGCGACAAGGGCGGCTTCGTGGGCATG
CATGATTTCGGCGCATCCGCCCCGGCGGAGGATCTGTACACGCATTTCGGCATCACAGCCGAAGATGTGGCTGCCAAGGT
GAAATCCCTGCTGTAG

Upstream 100 bases:

>100_bases
CTTCAATCGCCGCTGACGGGCGTCTCGCGCCTTGCACTTCAACTGGCCTTTGGTATCACGCCTCCAACCAATGCCTCCCG
CTGCCACAAAGGATCCCGCC

Downstream 100 bases:

>100_bases
AAACGACCGCCAGATCACACATTCTGGCCCGCTGGCGCATATCCGCGCTGGCGGGCTTTTTCGTATGTCACAGCCGGGAG
GTCGGAGGTGCGTCCACCCC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MDIKALASANPDHWARAACIRTLTLDAVAAANSGHSGMPMGMADVATVLFDKHLSFDASNPDWPNRDRFILSAGHGSMLI
YSLLHLTGYKDMTLEQIKNFRQLGAITAGHPEYGHVKGVETTTGPLGQGIANAVGFAMAEEHLRAKWGKKIIDHYTYCIA
GDGCLMEGISQEALALAGHQELSRLIVMWDNNNITIDGEVSLSDRTDQMARFAASGWDVFSCDGHDPADIDRALTEAKAS
PGPAMIACKTHIAIGSSAQDTGKGHGALTDDKLIADTKEAYGWPHAPFDIPKDLKSWWEGVGSKGAEARQAWEEQFDAMS
AGKRAEFNRTFAGEMPKKLSATIKAFKKQLSDEKPKVATRKASQMALEVINTVVPETLGGSADLTGSNLTNTGGLGTFAP
DDRKGRHIHYGIREHAMAAAMNGMILHGGVKPYGGTFFTFTDYARPSMRLAALMKIAPVYVMTHDSIGVGEDGPTHQPVE
HLAMLRATPNMNVFRPADAVETAEAWELALTSTDTPSTLALSRQGLPLLRTEHKTKNLTAQGGYVLADAEGKRQAILMAT
GSEVAIAMAARDLLQAEGIGTRVVSLPCWELFEAQDEAYRKRVLPGGPVRVAVEAAIRFGWDRWLYGERGKRDKGGFVGM
HDFGASAPAEDLYTHFGITAEDVAAKVKSLL

Sequences:

>Translated_671_residues
MDIKALASANPDHWARAACIRTLTLDAVAAANSGHSGMPMGMADVATVLFDKHLSFDASNPDWPNRDRFILSAGHGSMLI
YSLLHLTGYKDMTLEQIKNFRQLGAITAGHPEYGHVKGVETTTGPLGQGIANAVGFAMAEEHLRAKWGKKIIDHYTYCIA
GDGCLMEGISQEALALAGHQELSRLIVMWDNNNITIDGEVSLSDRTDQMARFAASGWDVFSCDGHDPADIDRALTEAKAS
PGPAMIACKTHIAIGSSAQDTGKGHGALTDDKLIADTKEAYGWPHAPFDIPKDLKSWWEGVGSKGAEARQAWEEQFDAMS
AGKRAEFNRTFAGEMPKKLSATIKAFKKQLSDEKPKVATRKASQMALEVINTVVPETLGGSADLTGSNLTNTGGLGTFAP
DDRKGRHIHYGIREHAMAAAMNGMILHGGVKPYGGTFFTFTDYARPSMRLAALMKIAPVYVMTHDSIGVGEDGPTHQPVE
HLAMLRATPNMNVFRPADAVETAEAWELALTSTDTPSTLALSRQGLPLLRTEHKTKNLTAQGGYVLADAEGKRQAILMAT
GSEVAIAMAARDLLQAEGIGTRVVSLPCWELFEAQDEAYRKRVLPGGPVRVAVEAAIRFGWDRWLYGERGKRDKGGFVGM
HDFGASAPAEDLYTHFGITAEDVAAKVKSLL
>Mature_671_residues
MDIKALASANPDHWARAACIRTLTLDAVAAANSGHSGMPMGMADVATVLFDKHLSFDASNPDWPNRDRFILSAGHGSMLI
YSLLHLTGYKDMTLEQIKNFRQLGAITAGHPEYGHVKGVETTTGPLGQGIANAVGFAMAEEHLRAKWGKKIIDHYTYCIA
GDGCLMEGISQEALALAGHQELSRLIVMWDNNNITIDGEVSLSDRTDQMARFAASGWDVFSCDGHDPADIDRALTEAKAS
PGPAMIACKTHIAIGSSAQDTGKGHGALTDDKLIADTKEAYGWPHAPFDIPKDLKSWWEGVGSKGAEARQAWEEQFDAMS
AGKRAEFNRTFAGEMPKKLSATIKAFKKQLSDEKPKVATRKASQMALEVINTVVPETLGGSADLTGSNLTNTGGLGTFAP
DDRKGRHIHYGIREHAMAAAMNGMILHGGVKPYGGTFFTFTDYARPSMRLAALMKIAPVYVMTHDSIGVGEDGPTHQPVE
HLAMLRATPNMNVFRPADAVETAEAWELALTSTDTPSTLALSRQGLPLLRTEHKTKNLTAQGGYVLADAEGKRQAILMAT
GSEVAIAMAARDLLQAEGIGTRVVSLPCWELFEAQDEAYRKRVLPGGPVRVAVEAAIRFGWDRWLYGERGKRDKGGFVGM
HDFGASAPAEDLYTHFGITAEDVAAKVKSLL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=575, Percent_Identity=25.9130434782609, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4507521, Length=575, Percent_Identity=25.9130434782609, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI133778974, Length=577, Percent_Identity=25.4766031195841, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI48994911, Length=666, Percent_Identity=50.7507507507508, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1788808, Length=667, Percent_Identity=48.4257871064468, Blast_Score=577, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI17539652, Length=576, Percent_Identity=26.3888888888889, Blast_Score=141, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325331, Length=671, Percent_Identity=42.9210134128167, Blast_Score=481, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=41.9019316493314, Blast_Score=478, Evalue=1e-135,
Organism=Drosophila melanogaster, GI45551847, Length=684, Percent_Identity=25.1461988304094, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI45550715, Length=684, Percent_Identity=25.1461988304094, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24645119, Length=657, Percent_Identity=25.1141552511416, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666278, Length=227, Percent_Identity=31.7180616740088, Blast_Score=109, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72356; Mature: 72356

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKALASANPDHWARAACIRTLTLDAVAAANSGHSGMPMGMADVATVLFDKHLSFDASN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PDWPNRDRFILSAGHGSMLIYSLLHLTGYKDMTLEQIKNFRQLGAITAGHPEYGHVKGVE
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCC
TTTGPLGQGIANAVGFAMAEEHLRAKWGKKIIDHYTYCIAGDGCLMEGISQEALALAGHQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHCCCHHHHHHHCHH
ELSRLIVMWDNNNITIDGEVSLSDRTDQMARFAASGWDVFSCDGHDPADIDRALTEAKAS
CCCEEEEEECCCEEEEEEEEECCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCC
PGPAMIACKTHIAIGSSAQDTGKGHGALTDDKLIADTKEAYGWPHAPFDIPKDLKSWWEG
CCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHHHHHHHH
VGSKGAEARQAWEEQFDAMSAGKRAEFNRTFAGEMPKKLSATIKAFKKQLSDEKPKVATR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCHHHH
KASQMALEVINTVVPETLGGSADLTGSNLTNTGGLGTFAPDDRKGRHIHYGIREHAMAAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHH
MNGMILHGGVKPYGGTFFTFTDYARPSMRLAALMKIAPVYVMTHDSIGVGEDGPTHQPVE
HCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHH
HLAMLRATPNMNVFRPADAVETAEAWELALTSTDTPSTLALSRQGLPLLRTEHKTKNLTA
HHHHHHCCCCCCEECCCHHHHHHHHHEEEEECCCCCCEEEECCCCCCHHCCCCCCCCEEE
QGGYVLADAEGKRQAILMATGSEVAIAMAARDLLQAEGIGTRVVSLPCWELFEAQDEAYR
CCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
KRVLPGGPVRVAVEAAIRFGWDRWLYGERGKRDKGGFVGMHDFGASAPAEDLYTHFGITA
HHCCCCCCEEEEEHHHHHHCHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCH
EDVAAKVKSLL
HHHHHHHHHCC
>Mature Secondary Structure
MDIKALASANPDHWARAACIRTLTLDAVAAANSGHSGMPMGMADVATVLFDKHLSFDASN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PDWPNRDRFILSAGHGSMLIYSLLHLTGYKDMTLEQIKNFRQLGAITAGHPEYGHVKGVE
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCC
TTTGPLGQGIANAVGFAMAEEHLRAKWGKKIIDHYTYCIAGDGCLMEGISQEALALAGHQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHCCCHHHHHHHCHH
ELSRLIVMWDNNNITIDGEVSLSDRTDQMARFAASGWDVFSCDGHDPADIDRALTEAKAS
CCCEEEEEECCCEEEEEEEEECCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCC
PGPAMIACKTHIAIGSSAQDTGKGHGALTDDKLIADTKEAYGWPHAPFDIPKDLKSWWEG
CCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCHHHHHHHHH
VGSKGAEARQAWEEQFDAMSAGKRAEFNRTFAGEMPKKLSATIKAFKKQLSDEKPKVATR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCHHHH
KASQMALEVINTVVPETLGGSADLTGSNLTNTGGLGTFAPDDRKGRHIHYGIREHAMAAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHH
MNGMILHGGVKPYGGTFFTFTDYARPSMRLAALMKIAPVYVMTHDSIGVGEDGPTHQPVE
HCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHH
HLAMLRATPNMNVFRPADAVETAEAWELALTSTDTPSTLALSRQGLPLLRTEHKTKNLTA
HHHHHHCCCCCCEECCCHHHHHHHHHEEEEECCCCCCEEEECCCCCCHHCCCCCCCCEEE
QGGYVLADAEGKRQAILMATGSEVAIAMAARDLLQAEGIGTRVVSLPCWELFEAQDEAYR
CCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
KRVLPGGPVRVAVEAAIRFGWDRWLYGERGKRDKGGFVGMHDFGASAPAEDLYTHFGITA
HHCCCCCCEEEEEHHHHHHCHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCH
EDVAAKVKSLL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8635754; 9256491 [H]