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The map label for this gene is aaeR [H]

Identifier: 89053808

GI number: 89053808

Start: 1281625

End: 1282551

Strand: Direct

Name: aaeR [H]

Synonym: Jann_1317

Alternate gene names: 89053808

Gene position: 1281625-1282551 (Clockwise)

Preceding gene: 89053804

Following gene: 89053809

Centisome position: 29.68

GC content: 62.68

Gene sequence:

>927_bases
ATGCGCACCCCTGTCGGTCTTGATGACCTTCGATATTTCTATCTGGTGGCCGAAGCCGGTGGCGTCAGCGCAGCTGCGCG
CAGGTTCGATATCTCAAAAGCCACGTTGTCGCGCGCGGTCGCCCGGCTTGAAGATCAGGCAAAGGGCCCGCTTTTTGACC
GGCTCAGCACCGGGTTACAACTGACCCAGGCCGGAGAGGCACTGATTGAGGCGGCCCGGCAGGCGACCGATGCGGGCAGC
ACCGCGGAGGAACTGCTGCGCACCGTCACGGAGGAGCCACAGGGGATGCTGCGGATCGCGGCAAGTGCGCTGAGTGGGCA
GTACCTTGTGGGCCCTGTTCTGGCGCGGTTGACCGAGGACTATCCCAAGGTGACGGCCCATGTCAGTGTCACCGCAAGTG
GCCCCGATCCCTTGGCCGAGGAGCTTGATCTTGTTTTGCGGCTGGGCCGCCCCGAGGAGCCGTACCTGATCGCACGCCGG
ATTATCGGGACGCCCATGAAGCTCTATTGCGGAACAGATTTCGCAAAGTCCAACCCCGTGACAGACCCGGAAGCCGTCAG
TCGGTTCGCGCGGGTCAGCATCAACGTTCCGGGCGCGCCAGCAAACTGGTTGTTGCATGACGACGCCGACAGAACCCTCA
CATTTGATATCGAGCCACGCATCTATGCAGGCGATCCCACCGTCGCAATCGGACTGGTCCATGCGGGGGCTGGTATCACG
CTGCTTCCTGCCCTTTATGGTGACTTGCTTGTCGAGCGTGGCGATGCGGCCGCCGTTCTGCCAACCTATGAAGGTGCCCC
GGTGGAGCTGTTTGCGGTGTTTCCGCCGCGGCGCTCCAGCGTGCCGGCAGTGCGGGTCTTCATTGATTACCTGACCGCGT
TCGCCAACGGGGCAGAGAAGAGTTTTGATCGCGGTTGGCCTGGCTAG

Upstream 100 bases:

>100_bases
TTTCAAAAATGGAACGCCCGACTCGAAAACTGTGCTTTAGGCTCTACCTGCACACCGTGGAGCCGCTGCACGCTGCCAAG
AAGGATCCGCCACATTGCCC

Downstream 100 bases:

>100_bases
TCGGGAGCAATGGAGCTGGCCCGCCGGGTCGCATTCGCCTTGGACTTTTGAAGGAACCACGTTTTGCCGCGCCGTTACGA
AGATATTTATCCGTCCCTCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRTPVGLDDLRYFYLVAEAGGVSAAARRFDISKATLSRAVARLEDQAKGPLFDRLSTGLQLTQAGEALIEAARQATDAGS
TAEELLRTVTEEPQGMLRIAASALSGQYLVGPVLARLTEDYPKVTAHVSVTASGPDPLAEELDLVLRLGRPEEPYLIARR
IIGTPMKLYCGTDFAKSNPVTDPEAVSRFARVSINVPGAPANWLLHDDADRTLTFDIEPRIYAGDPTVAIGLVHAGAGIT
LLPALYGDLLVERGDAAAVLPTYEGAPVELFAVFPPRRSSVPAVRVFIDYLTAFANGAEKSFDRGWPG

Sequences:

>Translated_308_residues
MRTPVGLDDLRYFYLVAEAGGVSAAARRFDISKATLSRAVARLEDQAKGPLFDRLSTGLQLTQAGEALIEAARQATDAGS
TAEELLRTVTEEPQGMLRIAASALSGQYLVGPVLARLTEDYPKVTAHVSVTASGPDPLAEELDLVLRLGRPEEPYLIARR
IIGTPMKLYCGTDFAKSNPVTDPEAVSRFARVSINVPGAPANWLLHDDADRTLTFDIEPRIYAGDPTVAIGLVHAGAGIT
LLPALYGDLLVERGDAAAVLPTYEGAPVELFAVFPPRRSSVPAVRVFIDYLTAFANGAEKSFDRGWPG
>Mature_308_residues
MRTPVGLDDLRYFYLVAEAGGVSAAARRFDISKATLSRAVARLEDQAKGPLFDRLSTGLQLTQAGEALIEAARQATDAGS
TAEELLRTVTEEPQGMLRIAASALSGQYLVGPVLARLTEDYPKVTAHVSVTASGPDPLAEELDLVLRLGRPEEPYLIARR
IIGTPMKLYCGTDFAKSNPVTDPEAVSRFARVSINVPGAPANWLLHDDADRTLTFDIEPRIYAGDPTVAIGLVHAGAGIT
LLPALYGDLLVERGDAAAVLPTYEGAPVELFAVFPPRRSSVPAVRVFIDYLTAFANGAEKSFDRGWPG

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=298, Percent_Identity=25.1677852348993, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=27.891156462585, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=24.5733788395904, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=21.4285714285714, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=22.8956228956229, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=23.5772357723577, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=32.4786324786325, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=23.5294117647059, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32974; Mature: 32974

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPVGLDDLRYFYLVAEAGGVSAAARRFDISKATLSRAVARLEDQAKGPLFDRLSTGLQ
CCCCCCHHHCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
LTQAGEALIEAARQATDAGSTAEELLRTVTEEPQGMLRIAASALSGQYLVGPVLARLTED
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
YPKVTAHVSVTASGPDPLAEELDLVLRLGRPEEPYLIARRIIGTPMKLYCGTDFAKSNPV
CCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
TDPEAVSRFARVSINVPGAPANWLLHDDADRTLTFDIEPRIYAGDPTVAIGLVHAGAGIT
CCHHHHHHHHEEEEECCCCCCCCEEECCCCCEEEEECCCEEEECCCCEEEEEEECCCCHH
LLPALYGDLLVERGDAAAVLPTYEGAPVELFAVFPPRRSSVPAVRVFIDYLTAFANGAEK
HHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHH
SFDRGWPG
HCCCCCCC
>Mature Secondary Structure
MRTPVGLDDLRYFYLVAEAGGVSAAARRFDISKATLSRAVARLEDQAKGPLFDRLSTGLQ
CCCCCCHHHCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
LTQAGEALIEAARQATDAGSTAEELLRTVTEEPQGMLRIAASALSGQYLVGPVLARLTED
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
YPKVTAHVSVTASGPDPLAEELDLVLRLGRPEEPYLIARRIIGTPMKLYCGTDFAKSNPV
CCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
TDPEAVSRFARVSINVPGAPANWLLHDDADRTLTFDIEPRIYAGDPTVAIGLVHAGAGIT
CCHHHHHHHHEEEEECCCCCCCCEEECCCCCEEEEECCCEEEECCCCEEEEEEECCCCHH
LLPALYGDLLVERGDAAAVLPTYEGAPVELFAVFPPRRSSVPAVRVFIDYLTAFANGAEK
HHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHH
SFDRGWPG
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]