| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is gno [H]
Identifier: 89053597
GI number: 89053597
Start: 1066949
End: 1067704
Strand: Direct
Name: gno [H]
Synonym: Jann_1106
Alternate gene names: 89053597
Gene position: 1066949-1067704 (Clockwise)
Preceding gene: 89053596
Following gene: 89053598
Centisome position: 24.71
GC content: 65.21
Gene sequence:
>756_bases ATGAGCCTGCCGCGTACCCCGTCATTCTCCCTCGCTGGACAGCGGGCGTTTGTGCCCGGCGGATCGCGCGGGATTGGCCT TGGATGCGCGGTCGCGCTGGCCGAGGCGGGGGCCCATGTGGTGATCGCCGCGCGGGGCAGGGATGCGGTGGACGCGGCTA TGGCCGAGATAACGCAGGCCGGGTTTTCGGCCGAGGGGATCACGCTCGACATCACCGATGTCGATGCGACCCGCGCCGCT GTTGCCGCTATGGGGCGGCTGGATATCCTGTGCAACTCCGCAGGCCTTGCGCGCCATACGCCTGCCACCGACACCACGCC CGAGGATTTCGATGCCGTGCAGGCCGTCAATGTGCGCGCCGCCTATTTTCTGGCGCAGGCCGCCGCCGCGCAGATGATTG ATGGCGGGTCGATCATTCAGGTCTCCAGCCAGATGGGTCATGTGGGCGGTATTGATCGCGCAGTCTATTGCGCCACAAAA CACGCGGTGGAAGGTTTCACCAAGGCCATGGCCATCGAATGGGGGCCGCGCAATATTCGCGTCAACACGCTGTGCCCCAC ATTCATTCGCACGCCGCTGACGGCCCCCACCTTCGCGGATCCCGAAAAACGCGCCTGGATCGAGAGCAAGATCAAGTTGC CGCGCGTGGCAGAGGTGGAGGATATCATGGGGGCGGTTCTGTTTCTGGCATCGGGTGCCAGCGCCATGGTGACGGGCACG TCGATCCTTGTCGACGGGGGATGGACGGCGGGATGA
Upstream 100 bases:
>100_bases GAGACCTGAACTTGACGAAATGCCTCCAATTCATAGGCTTATCCCCAGAATTTTCCCTAGAGCGTGTGAAAATCGAACCT TTCCCGGACGGAGCCGTGTC
Downstream 100 bases:
>100_bases TTGATCGCGCGCCCATTACAGGGAAAGTCACCTCCATCGACGTGGCGCAGCGGGCAGGCGTCAGCCAATCGGCGGTCAGC CGGGTCTTCACGCCGGGGGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MSLPRTPSFSLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQAGFSAEGITLDITDVDATRAA VAAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRAAYFLAQAAAAQMIDGGSIIQVSSQMGHVGGIDRAVYCATK HAVEGFTKAMAIEWGPRNIRVNTLCPTFIRTPLTAPTFADPEKRAWIESKIKLPRVAEVEDIMGAVLFLASGASAMVTGT SILVDGGWTAG
Sequences:
>Translated_251_residues MSLPRTPSFSLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQAGFSAEGITLDITDVDATRAA VAAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRAAYFLAQAAAAQMIDGGSIIQVSSQMGHVGGIDRAVYCATK HAVEGFTKAMAIEWGPRNIRVNTLCPTFIRTPLTAPTFADPEKRAWIESKIKLPRVAEVEDIMGAVLFLASGASAMVTGT SILVDGGWTAG >Mature_250_residues SLPRTPSFSLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQAGFSAEGITLDITDVDATRAAV AAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRAAYFLAQAAAAQMIDGGSIIQVSSQMGHVGGIDRAVYCATKH AVEGFTKAMAIEWGPRNIRVNTLCPTFIRTPLTAPTFADPEKRAWIESKIKLPRVAEVEDIMGAVLFLASGASAMVTGTS ILVDGGWTAG
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=37.8600823045267, Blast_Score=152, Evalue=3e-37, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=34.4262295081967, Blast_Score=121, Evalue=5e-28, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=33.4710743801653, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI66933014, Length=227, Percent_Identity=32.15859030837, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=32.6612903225806, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=32.2033898305085, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=32.4, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=30.1204819277108, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=34.7368421052632, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.1746031746032, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=32.3275862068966, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=27.1844660194175, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI4503817, Length=214, Percent_Identity=27.1028037383178, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4504505, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=33.1491712707182, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI7705855, Length=216, Percent_Identity=28.2407407407407, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=28.9855072463768, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=26.6932270916335, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=24.7572815533981, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=38.0952380952381, Blast_Score=153, Evalue=9e-39, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=37.3983739837398, Blast_Score=140, Evalue=5e-35, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=30.6122448979592, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.1967213114754, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=31.8367346938775, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=31.1023622047244, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=31.3253012048193, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=31.1740890688259, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.5573770491803, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=28.5171102661597, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.241935483871, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=30.5439330543933, Blast_Score=78, Evalue=4e-16, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.1138211382114, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=35.0806451612903, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=33.469387755102, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=32.6530612244898, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=32.3886639676113, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.8387096774194, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=29.8850574712644, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=30.4182509505703, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=29.4776119402985, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=30, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.4573643410853, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.030303030303, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=29.2929292929293, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=26.3565891472868, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=31.0185185185185, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=26.7441860465116, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71997099, Length=214, Percent_Identity=30.3738317757009, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.1363636363636, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=24.6073298429319, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=25.1336898395722, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71997402, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17551412, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=25.4826254826255, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=25, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17558628, Length=197, Percent_Identity=29.9492385786802, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=25.3787878787879, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=28.4974093264249, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=34.7280334728033, Blast_Score=134, Evalue=7e-32, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=32.4, Blast_Score=113, Evalue=9e-26, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=34.251968503937, Blast_Score=110, Evalue=6e-25, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=32.1285140562249, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=32.156862745098, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI24644337, Length=225, Percent_Identity=29.7777777777778, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI18859837, Length=187, Percent_Identity=31.5508021390374, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640492, Length=207, Percent_Identity=25.1207729468599, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI221510726, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.5275590551181, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 25899; Mature: 25768
Theoretical pI: Translated: 5.66; Mature: 5.66
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLPRTPSFSLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQA CCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC GFSAEGITLDITDVDATRAAVAAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRA CCCCCCEEEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH AYFLAQAAAAQMIDGGSIIQVSSQMGHVGGIDRAVYCATKHAVEGFTKAMAIEWGPRNIR HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEE VNTLCPTFIRTPLTAPTFADPEKRAWIESKIKLPRVAEVEDIMGAVLFLASGASAMVTGT EEEECHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC SILVDGGWTAG EEEEECCCCCC >Mature Secondary Structure SLPRTPSFSLAGQRAFVPGGSRGIGLGCAVALAEAGAHVVIAARGRDAVDAAMAEITQA CCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC GFSAEGITLDITDVDATRAAVAAMGRLDILCNSAGLARHTPATDTTPEDFDAVQAVNVRA CCCCCCEEEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH AYFLAQAAAAQMIDGGSIIQVSSQMGHVGGIDRAVYCATKHAVEGFTKAMAIEWGPRNIR HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEE VNTLCPTFIRTPLTAPTFADPEKRAWIESKIKLPRVAEVEDIMGAVLFLASGASAMVTGT EEEECHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC SILVDGGWTAG EEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]