BacMap

Definition	Ehrlichia chaffeensis str. Arkansas, complete genome.
Accession	NC_007799
Length	1,176,248

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The map label for this gene is fabG [H]

Identifier: 88658561

GI number: 88658561

Start: 682529

End: 683272

Strand: Direct

Name: fabG [H]

Synonym: ECH_0669

Alternate gene names: 88658561

Gene position: 682529-683272 (Clockwise)

Preceding gene: 88658137

Following gene: 88657650

Centisome position: 58.03

GC content: 35.48

Gene sequence:

>744_bases
ATGTTCAATTTGTCACAAAAAAGATTTCTGATTACTGGAGCATCTGGTGGTATTGGAAAAGCTATAACTAAAACTTTATC
AAATGCAGGAGCTATCCTGTGTATTTCAGGTACTAAAGCACCTGTATTGCAGGAAATTGCAGAACAATACTCAAGTGCAG
GTAACATATATACTTTACCTTGTGATTTAACAAACGATGAACAGATTAATAGCTTAATTGACAATGCATGCAAGGCTATG
TCTGGTATTGATGGCATAATATGCAATGCCGGCATTACCTTAGATAAACTCACATTACGTACCTCTGATGAAGACTGGCA
CAAAGTTATCAACACAAACTTAACCACAACCTTTAAACTAAACCGCAATGCATGTCGTGCAATGTTAAAAAACAATCAAG
GAAGGATAATTAACATATCTTCAATTATAGCATTTACCGGCAATCCTGGACAAGCAAGTTACTCAGCATCCAAAGCTGGT
ATGATAGCTATGAGTAAATCCATAGCAAAAGAGTTTGCAAACCGCAATATAACTGTAAATTGTATAGCTCCAGGGTTTAT
TGAAACACCAATGACAGATGCATTATCAGAAGAACAACGTAACAACATTATAACACATATCCCAATGAAGAGGATAGGTA
CACCAGAAGAAGTAGCTGCTGCAGTTTTATTTTTAGCCAGCGATGAAAGTAAATATATTACAGGCCAAACTTTACACATA
AATGGTGGAATGTTAATGTATTAA

Upstream 100 bases:

>100_bases
TATCCTTTATCATATTTAATTTCAGTTTAAGAATACAACCCTTTACTTTCCATTATAAATAAAGTAGCATGCCCATATTT
GAGTTAACGTTAGGGTTTAC

Downstream 100 bases:

>100_bases
TGTGGTACAATGCTAATACACTAATTTATAAAGACACATGTTTCTTTTTAAAAAAGCAACATATAAAACCAAATATTATA
TAGCACTTTGTGCTAATACT

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MFNLSQKRFLITGASGGIGKAITKTLSNAGAILCISGTKAPVLQEIAEQYSSAGNIYTLPCDLTNDEQINSLIDNACKAM
SGIDGIICNAGITLDKLTLRTSDEDWHKVINTNLTTTFKLNRNACRAMLKNNQGRIINISSIIAFTGNPGQASYSASKAG
MIAMSKSIAKEFANRNITVNCIAPGFIETPMTDALSEEQRNNIITHIPMKRIGTPEEVAAAVLFLASDESKYITGQTLHI
NGGMLMY

Sequences:

>Translated_247_residues
MFNLSQKRFLITGASGGIGKAITKTLSNAGAILCISGTKAPVLQEIAEQYSSAGNIYTLPCDLTNDEQINSLIDNACKAM
SGIDGIICNAGITLDKLTLRTSDEDWHKVINTNLTTTFKLNRNACRAMLKNNQGRIINISSIIAFTGNPGQASYSASKAG
MIAMSKSIAKEFANRNITVNCIAPGFIETPMTDALSEEQRNNIITHIPMKRIGTPEEVAAAVLFLASDESKYITGQTLHI
NGGMLMY
>Mature_247_residues
MFNLSQKRFLITGASGGIGKAITKTLSNAGAILCISGTKAPVLQEIAEQYSSAGNIYTLPCDLTNDEQINSLIDNACKAM
SGIDGIICNAGITLDKLTLRTSDEDWHKVINTNLTTTFKLNRNACRAMLKNNQGRIINISSIIAFTGNPGQASYSASKAG
MIAMSKSIAKEFANRNITVNCIAPGFIETPMTDALSEEQRNNIITHIPMKRIGTPEEVAAAVLFLASDESKYITGQTLHI
NGGMLMY

Specific function: Proposed to modify Nod factor fatty acyl chain [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=36.4372469635627, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=34.0336134453782, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=31.5573770491803, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=31.8548387096774, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=29.1497975708502, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=32.48730964467, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=30, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI66933014, Length=208, Percent_Identity=31.7307692307692, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4504505, Length=229, Percent_Identity=31.0043668122271, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=31.5126050420168, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4503301, Length=226, Percent_Identity=30.5309734513274, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI83715985, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=26.1224489795918, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=28.7292817679558, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI20149619, Length=222, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=26.2626262626263, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=243, Percent_Identity=23.8683127572016, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI210032110, Length=202, Percent_Identity=24.2574257425743, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=225, Percent_Identity=26.2222222222222, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4557649, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=46.530612244898, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=34.9397590361446, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=30.9236947791165, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.0158102766798, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=31.6, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=32.2314049586777, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=32.0158102766798, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=30.4, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.0836653386454, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=29.2682926829268, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=26.2745098039216, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=26.9387755102041, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=28.5, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787545, Length=251, Percent_Identity=24.7011952191235, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=40, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=36.4754098360656, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=31.8367346938775, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.1023622047244, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=29.4820717131474, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=30.0813008130081, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=30.4878048780488, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.3893129770992, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=29.1497975708502, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=30.9433962264151, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=28.2442748091603, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.4339622641509, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=29.6577946768061, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.7709923664122, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=27.4809160305344, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=28.2527881040892, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=26.3358778625954, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=27.3076923076923, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.7566539923954, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=26.2357414448669, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=30.3501945525292, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.9961977186312, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563809, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507613, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=27.4809160305344, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=25.4826254826255, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=27.6497695852535, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=26.7441860465116, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=26.1802575107296, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.2948207171315, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=31.7460317460317, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=26.0204081632653, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=246, Percent_Identity=26.4227642276423, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=237, Percent_Identity=27.0042194092827, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=216, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193210355, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324126, Length=244, Percent_Identity=26.2295081967213, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=34.4262295081967, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.8548387096774, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=31.4741035856574, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=30, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.8, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=32.5301204819277, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=27.9835390946502, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=29.7435897435897, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859837, Length=184, Percent_Identity=32.0652173913043, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24663911, Length=236, Percent_Identity=26.271186440678, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648944, Length=230, Percent_Identity=25.6521739130435, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=28.8, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=23.5042735042735, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648693, Length=226, Percent_Identity=25.2212389380531, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355889, Length=226, Percent_Identity=25.2212389380531, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=228, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26542; Mature: 26542

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLSQKRFLITGASGGIGKAITKTLSNAGAILCISGTKAPVLQEIAEQYSSAGNIYTLP
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
CDLTNDEQINSLIDNACKAMSGIDGIICNAGITLDKLTLRTSDEDWHKVINTNLTTTFKL
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEEE
NRNACRAMLKNNQGRIINISSIIAFTGNPGQASYSASKAGMIAMSKSIAKEFANRNITVN
CHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
CIAPGFIETPMTDALSEEQRNNIITHIPMKRIGTPEEVAAAVLFLASDESKYITGQTLHI
EECCCCCCCCCHHHHHHHHHCCEEEECCHHHCCCHHHHHHEEEEEECCCCCEEECEEEEE
NGGMLMY
CCCEEEC
>Mature Secondary Structure
MFNLSQKRFLITGASGGIGKAITKTLSNAGAILCISGTKAPVLQEIAEQYSSAGNIYTLP
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
CDLTNDEQINSLIDNACKAMSGIDGIICNAGITLDKLTLRTSDEDWHKVINTNLTTTFKL
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEEE
NRNACRAMLKNNQGRIINISSIIAFTGNPGQASYSASKAGMIAMSKSIAKEFANRNITVN
CHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
CIAPGFIETPMTDALSEEQRNNIITHIPMKRIGTPEEVAAAVLFLASDESKYITGQTLHI
EECCCCCCCCCHHHHHHHHHCCEEEECCHHHCCCHHHHHHEEEEEECCCCCEEECEEEEE
NGGMLMY
CCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9100384 [H]