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The map label for this gene is acpS

Identifier: 88658154

GI number: 88658154

Start: 750437

End: 750808

Strand: Direct

Name: acpS

Synonym: ECH_0741

Alternate gene names: 88658154

Gene position: 750437-750808 (Clockwise)

Preceding gene: 88657672

Following gene: 88658634

Centisome position: 63.8

GC content: 29.57

Gene sequence:

>372_bases
ATGATACTAGGGATTGGTACAGACATTGTTTATGTTCCTCGTATATCAAATTTATGGAAAAAATTTGGTACTAAATTTCT
TAAACGGGTATTTAGTGAAAAAGAAATAGAAGATAGTAAGAAATATACAAATTTTGATGCACAAGTAAGACACTTTGCAA
AACGTTTCGCAGCAAAGGAAGCTTATGTGAAAGCTGTAGGAACAGGTTTTGGAAAATCCATAAAAATGCCAGATATTATA
GTATCTAACAACCTACACGGCAAACCACAAATTACCATAAATAATAGTAATATAAAATATAAAATTGAATTATCAATCAG
TGATGAAAAAGACTACGCTATTGCTTTTGTGGTTCTATATACAGAGTTATAA

Upstream 100 bases:

>100_bases
GTAAATCAACAGTAGAACAAGACCTTATTGAAGTAAGGAATAGATTAACAAAAGATAAAGTTTTAATTTCCACAGAACAA
TTCTTAAATAAATTAAAAAA

Downstream 100 bases:

>100_bases
CACTTGATATAGAACATAATACAACACAAATAACATATGGAAAAATTATAAACAATCAGCAGATACAAGACAAATCAACA
TGATAAGTACGCTATTGTTT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKEAYVKAVGTGFGKSIKMPDII
VSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLYTEL

Sequences:

>Translated_123_residues
MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKEAYVKAVGTGFGKSIKMPDII
VSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLYTEL
>Mature_123_residues
MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKEAYVKAVGTGFGKSIKMPDII
VSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLYTEL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=34.4, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_EHRCR (Q2GG91)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507542.1
- ProteinModelPortal:   Q2GG91
- SMR:   Q2GG91
- STRING:   Q2GG91
- GeneID:   3927178
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0741
- TIGR:   ECH_0741
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   DYAIAFI
- PhylomeDB:   Q2GG91
- ProtClustDB:   PRK14659
- BioCyc:   ECHA205920:ECH_0741-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14054; Mature: 14054

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKE
CEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
AYVKAVGTGFGKSIKMPDIIVSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLY
HHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEEEECCCCCEEEEEEEEE
TEL
ECC
>Mature Secondary Structure
MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKE
CEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
AYVKAVGTGFGKSIKMPDIIVSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLY
HHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEEEECCCCCEEEEEEEEE
TEL
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA