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The map label for this gene is dnaX [H]

Identifier: 88658108

GI number: 88658108

Start: 817801

End: 818688

Strand: Direct

Name: dnaX [H]

Synonym: ECH_0803

Alternate gene names: 88658108

Gene position: 817801-818688 (Clockwise)

Preceding gene: 88658214

Following gene: 88657616

Centisome position: 69.53

GC content: 26.8

Gene sequence:

>888_bases
ATGGATCAAATTATAGGGCACACATTAGCAAAAAATACACTAATACATAATACTCATATACAATCATGGTTAATATATGG
TAACAGAGGTATTGGGAAAGCAACACTTGCATATCGTTTTGCTAAATACCTAACACAATCAACATATTTAAATCATTATA
ACCCTGATCTTTTAACAATTAATGACAATGAAGAAATAATAGGAATAGACAAAATTAGAAATATAAAAAACTTTCTCTAT
TTAAGTACAGCAAGACTCAAATATAGAATAGTAATAGTAGATAGCATTGATAGCCTAACCATTAATGCCACTAATGCAAT
GCTTAAGATTCTCGAAGAAACACCTAATAACTCTATTATCATATTAATTAGCCACAATTTGCATGAAGTTCCAACAGTTG
TAAGATCAAGATGTTTTACATTAGGATTATCAGACCTTAATCCACAAGAAACACAACAAGTAATTCAAAATAACTTTCCC
CATTTAGATCATAAAAAAATAAGTCATATCTATCCAGGCACCCCAGGAATGGTAGGTCAACACATTGATCAAGAAATTGA
ACTATATAAAGCTCTTATTTCAATACTTACCAATCAATACAATAATATAACTATAGAAAACATCATAACAACTGAGATCA
GCTTTTATAAAGTAGAACATATACTATTTACTATTATGTTGGATCTAGCAAAAGAAATATTAGGTATAACAACTAATTTA
AGTATCTACAAACACCTAATAGACAATATAAAGAATAAAATTAACATCAATCAATTGCTAATAAAAGTATCTCAAATACA
ACAATTAATATCTTATGCAAAAAAATTTCAACTAGATAAAAAATCAGTAATGCTAAATTTGATCAATACCATAATTAATT
TACTATAA

Upstream 100 bases:

>100_bases
AAATAAAATCAGTGTTTACAAAAAAAAATATCTACGCCATACTGATCAACATAATACTAGTTGTACTTAAATTAAAGATA
CCTAATCAAAATTTTTAAAT

Downstream 100 bases:

>100_bases
ACTACTATTAATTTTCTTGAAAATTTAATATATTAGAATTGGTATTAATAATACTATATAAAACATAAATGGAAAAAATT
ACCACAAACATTTAAACACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDQIIGHTLAKNTLIHNTHIQSWLIYGNRGIGKATLAYRFAKYLTQSTYLNHYNPDLLTINDNEEIIGIDKIRNIKNFLY
LSTARLKYRIVIVDSIDSLTINATNAMLKILEETPNNSIIILISHNLHEVPTVVRSRCFTLGLSDLNPQETQQVIQNNFP
HLDHKKISHIYPGTPGMVGQHIDQEIELYKALISILTNQYNNITIENIITTEISFYKVEHILFTIMLDLAKEILGITTNL
SIYKHLIDNIKNKININQLLIKVSQIQQLISYAKKFQLDKKSVMLNLINTIINLL

Sequences:

>Translated_295_residues
MDQIIGHTLAKNTLIHNTHIQSWLIYGNRGIGKATLAYRFAKYLTQSTYLNHYNPDLLTINDNEEIIGIDKIRNIKNFLY
LSTARLKYRIVIVDSIDSLTINATNAMLKILEETPNNSIIILISHNLHEVPTVVRSRCFTLGLSDLNPQETQQVIQNNFP
HLDHKKISHIYPGTPGMVGQHIDQEIELYKALISILTNQYNNITIENIITTEISFYKVEHILFTIMLDLAKEILGITTNL
SIYKHLIDNIKNKININQLLIKVSQIQQLISYAKKFQLDKKSVMLNLINTIINLL
>Mature_295_residues
MDQIIGHTLAKNTLIHNTHIQSWLIYGNRGIGKATLAYRFAKYLTQSTYLNHYNPDLLTINDNEEIIGIDKIRNIKNFLY
LSTARLKYRIVIVDSIDSLTINATNAMLKILEETPNNSIIILISHNLHEVPTVVRSRCFTLGLSDLNPQETQQVIQNNFP
HLDHKKISHIYPGTPGMVGQHIDQEIELYKALISILTNQYNNITIENIITTEISFYKVEHILFTIMLDLAKEILGITTNL
SIYKHLIDNIKNKININQLLIKVSQIQQLISYAKKFQLDKKSVMLNLINTIINLL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 33869; Mature: 33869

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIIGHTLAKNTLIHNTHIQSWLIYGNRGIGKATLAYRFAKYLTQSTYLNHYNPDLLTI
CCCHHHHHHHHCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
NDNEEIIGIDKIRNIKNFLYLSTARLKYRIVIVDSIDSLTINATNAMLKILEETPNNSII
CCCCCEEEHHHHHHHHHHHEEEEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCEE
ILISHNLHEVPTVVRSRCFTLGLSDLNPQETQQVIQNNFPHLDHKKISHIYPGTPGMVGQ
EEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHH
HIDQEIELYKALISILTNQYNNITIENIITTEISFYKVEHILFTIMLDLAKEILGITTNL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SIYKHLIDNIKNKININQLLIKVSQIQQLISYAKKFQLDKKSVMLNLINTIINLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDQIIGHTLAKNTLIHNTHIQSWLIYGNRGIGKATLAYRFAKYLTQSTYLNHYNPDLLTI
CCCHHHHHHHHCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
NDNEEIIGIDKIRNIKNFLYLSTARLKYRIVIVDSIDSLTINATNAMLKILEETPNNSII
CCCCCEEEHHHHHHHHHHHEEEEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHCCCCCEE
ILISHNLHEVPTVVRSRCFTLGLSDLNPQETQQVIQNNFPHLDHKKISHIYPGTPGMVGQ
EEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHH
HIDQEIELYKALISILTNQYNNITIENIITTEISFYKVEHILFTIMLDLAKEILGITTNL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SIYKHLIDNIKNKININQLLIKVSQIQQLISYAKKFQLDKKSVMLNLINTIINLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]