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The map label for this gene is bioC [C]

Identifier: 88607173

GI number: 88607173

Start: 23719

End: 24477

Strand: Direct

Name: bioC [C]

Synonym: APH_0025

Alternate gene names: 88607173

Gene position: 23719-24477 (Clockwise)

Preceding gene: 88607215

Following gene: 88607747

Centisome position: 1.61

GC content: 37.68

Gene sequence:

>759_bases
ATGGAAAAGGAATATGTTAAAAGGGTGAAGGTTTGTTTCAACAAAGCCGCATTAACCTATGATTACAGCACGTCTTTACA
GAGTAAAGTAGCAAAGAAAATATGTTCTTTTATTGGCGATATAGAGAACAATAATCTAGTTTTAGATGTTGGTTGTGGAA
CAGGTTATGTTGGCCAACAATTAGGAGTTGATGACCAGCTATATCAGGTTGATATTTCTCACGAGATGTGCTGCACAGCC
TCAAGAAAGGTTAAGGCTATTAGTACTATCAACTGCGATATGCAATTTCTTCCATTTGCCCCTGACTCTTTTGATATTGT
AGTACTATCTATGTCGCTGCATTGGGCAGTAGATCTATTAGGTGCCCTCCGTAGCGTATGCAGAGTCCAAAAAAAATCAG
GGCGTGGTATCTTCATTAGTATTCCAGTTACTGGAACTCTGGAAGAGTTGTGCATCTGTAATAAACTGCTCGGAAGAAAT
AGGAGATTTGAGTATTACGACGTGTCTCACATCACTCATGCTATTACTTCTCTAGGTTGTAAAGTTGAGCATATAGAGTG
TGAAAAGTTAGAGATACACCACAGAACTTTTTTTGACATGCTGTCTTCCTTAGTGAAAATGGGTTCTTCTGCACACAAAT
ATGGTACTGACTGCAAAGTTAGCATTATGGATGTGTGTCGCGTATATAACAGGCTATTTTCTAGGGAAGATTCAGTAGTT
AGTTCATGGAATATAGCTTATTTAGTTATCAAAAAATAA

Upstream 100 bases:

>100_bases
TGTTATAACCACTATAAAGATCTAGAATAAAGTACACGGTTTTTTATGCATTTTTTGCATAAAGGGACAATGTGATAATT
TCTAGAGGTGTTTTTATCCT

Downstream 100 bases:

>100_bases
TTTTACTGATATTGTTAATAAGTTTTTCATTGATACTGATGTTTTAGGCAATTGTCATGCTGCAGGAACATCGCGATTTA
TTACGCGAAATTAGGGATAT

Product: putative biotin synthesis protein BioC

Products: NA

Alternate protein names: Methyltransferase Type; Biotin Biosynthesis Protein BioC; Methyltransferase; Biotin Synthesis Protein; Methyltransferase UbiE/COQ5 Family; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Biotin Biosynthesis Methyltransferase BioC; UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase; Methyltransferase Domain Family Protein; Methylase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEKEYVKRVKVCFNKAALTYDYSTSLQSKVAKKICSFIGDIENNNLVLDVGCGTGYVGQQLGVDDQLYQVDISHEMCCTA
SRKVKAISTINCDMQFLPFAPDSFDIVVLSMSLHWAVDLLGALRSVCRVQKKSGRGIFISIPVTGTLEELCICNKLLGRN
RRFEYYDVSHITHAITSLGCKVEHIECEKLEIHHRTFFDMLSSLVKMGSSAHKYGTDCKVSIMDVCRVYNRLFSREDSVV
SSWNIAYLVIKK

Sequences:

>Translated_252_residues
MEKEYVKRVKVCFNKAALTYDYSTSLQSKVAKKICSFIGDIENNNLVLDVGCGTGYVGQQLGVDDQLYQVDISHEMCCTA
SRKVKAISTINCDMQFLPFAPDSFDIVVLSMSLHWAVDLLGALRSVCRVQKKSGRGIFISIPVTGTLEELCICNKLLGRN
RRFEYYDVSHITHAITSLGCKVEHIECEKLEIHHRTFFDMLSSLVKMGSSAHKYGTDCKVSIMDVCRVYNRLFSREDSVV
SSWNIAYLVIKK
>Mature_252_residues
MEKEYVKRVKVCFNKAALTYDYSTSLQSKVAKKICSFIGDIENNNLVLDVGCGTGYVGQQLGVDDQLYQVDISHEMCCTA
SRKVKAISTINCDMQFLPFAPDSFDIVVLSMSLHWAVDLLGALRSVCRVQKKSGRGIFISIPVTGTLEELCICNKLLGRN
RRFEYYDVSHITHAITSLGCKVEHIECEKLEIHHRTFFDMLSSLVKMGSSAHKYGTDCKVSIMDVCRVYNRLFSREDSVV
SSWNIAYLVIKK

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=246, Percent_Identity=27.6422764227642, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 28438; Mature: 28438

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEYVKRVKVCFNKAALTYDYSTSLQSKVAKKICSFIGDIENNNLVLDVGCGTGYVGQQ
CCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
LGVDDQLYQVDISHEMCCTASRKVKAISTINCDMQFLPFAPDSFDIVVLSMSLHWAVDLL
CCCCCCEEEEECCHHHHHCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEEHHHHHHHHH
GALRSVCRVQKKSGRGIFISIPVTGTLEELCICNKLLGRNRRFEYYDVSHITHAITSLGC
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCC
KVEHIECEKLEIHHRTFFDMLSSLVKMGSSAHKYGTDCKVSIMDVCRVYNRLFSREDSVV
EEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCE
SSWNIAYLVIKK
ECCCEEEEEEEC
>Mature Secondary Structure
MEKEYVKRVKVCFNKAALTYDYSTSLQSKVAKKICSFIGDIENNNLVLDVGCGTGYVGQQ
CCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
LGVDDQLYQVDISHEMCCTASRKVKAISTINCDMQFLPFAPDSFDIVVLSMSLHWAVDLL
CCCCCCEEEEECCHHHHHCCCCCEEEEEEECCCEEEECCCCCCCEEEEEEEHHHHHHHHH
GALRSVCRVQKKSGRGIFISIPVTGTLEELCICNKLLGRNRRFEYYDVSHITHAITSLGC
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCC
KVEHIECEKLEIHHRTFFDMLSSLVKMGSSAHKYGTDCKVSIMDVCRVYNRLFSREDSVV
EEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCE
SSWNIAYLVIKK
ECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA