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The map label for this gene is cobS [H]

Identifier: 87200904

GI number: 87200904

Start: 3110927

End: 3111907

Strand: Direct

Name: cobS [H]

Synonym: Saro_2891

Alternate gene names: 87200904

Gene position: 3110927-3111907 (Clockwise)

Preceding gene: 87200895

Following gene: 87200908

Centisome position: 87.35

GC content: 63.91

Gene sequence:

>981_bases
ATGAGCGAACTTCCGAACAGCCACGCGACGACGCTGCTCGCCGCGCCCGACACCGAAATCGATGTCCGCGAAACCTTCGG
CATCGACATCGACATGAAGGTTCCCGCCTTTTCGCGGGCGGACGAGCGCGTGCCCGACCGCGACGACACCTACGTGTTCG
ATCCGGACACGACTCTCGCGATCCTTGCGGGCTTTGCCTACAATCGGCGCGTGATGGTCCAGGGCTATCACGGCACGGGC
AAGTCGACGCACATCGAACAGGTTGCGGCGCGCCTCAACTGGCCCTGCATCCGCATCAACCTCGACGCGCACATCAGCCG
CATCGACCTTGTCGGTCGTGACGCGATCGTGCTGCGCGACGGGCTGCAGGTGACCGAGTTCCGCGAAGGCCTGCTGCCGT
GGGCATTGCAGACCCCGACCGCGCTGGTCTTCGACGAATACGATGCGGGCCGTCCCGACGTGATGTTCGTGATCCAGCGC
GTGCTGGAAACCGAGGGCAAGCTGACCCTGCTCGACCAGAACCGCGTGATCCGCCCGAACAAGTTCTTCCGCCTCTTCGC
GACGGCCAACACGGTGGGCCTTGGCGACACCTCGGGCCTCTATCACGGCACCCAGGCGATCAACCAGGGCCAGATGGACC
GCTGGAACCTCGTCGTGGCACTGAACTACCTGCCCGAGGCGACCGAGGTGGAGATCGTCACCAAGAAGGTGCCCGATCTC
GACCCGAAGATCGTGACCGACATGGTGCGCGTGGCGAACCTGACGCGTCAGGGCTTCATCAATGGCGACATTTCGACCGT
GATGAGCCCGCGCACGGTGATCAGCTGGGCGCAGAACAGCCAGATCTTCAACGACGTCGGCTTCGCCTTCCGCCTGTCGT
TCCTCAACAAGTGCGACGAGACGGAACGCGTGCTCGTGGCCGAATACTACCAGCGCGTGTTCGGCAAGGATCTGCCGGAA
AGCGTCGCGCACCGGGGTTGA

Upstream 100 bases:

>100_bases
CAGCGCACCGTAGAGCTTCATCGAAATTCTCCCATTCTATCGGACAGGTCTTCTGAAACCTTATTGCAGCGCCGCGCCCG
CCCGTATAGGCGGGGCAGCG

Downstream 100 bases:

>100_bases
GACCGCCGGCGCTGAAATGGAAAAAGGCCCCTGCGAGAGCGGGGGCCTTTCTTCGTCGGCTCAGCCGTTGGGCGTGATCA
GGTACTTCTCGCCGGTGCGC

Product: hydrogenobyrinic acid a,c-diamide cobaltochelatase

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSELPNSHATTLLAAPDTEIDVRETFGIDIDMKVPAFSRADERVPDRDDTYVFDPDTTLAILAGFAYNRRVMVQGYHGTG
KSTHIEQVAARLNWPCIRINLDAHISRIDLVGRDAIVLRDGLQVTEFREGLLPWALQTPTALVFDEYDAGRPDVMFVIQR
VLETEGKLTLLDQNRVIRPNKFFRLFATANTVGLGDTSGLYHGTQAINQGQMDRWNLVVALNYLPEATEVEIVTKKVPDL
DPKIVTDMVRVANLTRQGFINGDISTVMSPRTVISWAQNSQIFNDVGFAFRLSFLNKCDETERVLVAEYYQRVFGKDLPE
SVAHRG

Sequences:

>Translated_326_residues
MSELPNSHATTLLAAPDTEIDVRETFGIDIDMKVPAFSRADERVPDRDDTYVFDPDTTLAILAGFAYNRRVMVQGYHGTG
KSTHIEQVAARLNWPCIRINLDAHISRIDLVGRDAIVLRDGLQVTEFREGLLPWALQTPTALVFDEYDAGRPDVMFVIQR
VLETEGKLTLLDQNRVIRPNKFFRLFATANTVGLGDTSGLYHGTQAINQGQMDRWNLVVALNYLPEATEVEIVTKKVPDL
DPKIVTDMVRVANLTRQGFINGDISTVMSPRTVISWAQNSQIFNDVGFAFRLSFLNKCDETERVLVAEYYQRVFGKDLPE
SVAHRG
>Mature_325_residues
SELPNSHATTLLAAPDTEIDVRETFGIDIDMKVPAFSRADERVPDRDDTYVFDPDTTLAILAGFAYNRRVMVQGYHGTGK
STHIEQVAARLNWPCIRINLDAHISRIDLVGRDAIVLRDGLQVTEFREGLLPWALQTPTALVFDEYDAGRPDVMFVIQRV
LETEGKLTLLDQNRVIRPNKFFRLFATANTVGLGDTSGLYHGTQAINQGQMDRWNLVVALNYLPEATEVEIVTKKVPDLD
PKIVTDMVRVANLTRQGFINGDISTVMSPRTVISWAQNSQIFNDVGFAFRLSFLNKCDETERVLVAEYYQRVFGKDLPES
VAHRG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=247, Percent_Identity=23.4817813765182, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36674; Mature: 36543

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELPNSHATTLLAAPDTEIDVRETFGIDIDMKVPAFSRADERVPDRDDTYVFDPDTTLA
CCCCCCCCCEEEEECCCCCEEEHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCHHH
ILAGFAYNRRVMVQGYHGTGKSTHIEQVAARLNWPCIRINLDAHISRIDLVGRDAIVLRD
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCEEEEEC
GLQVTEFREGLLPWALQTPTALVFDEYDAGRPDVMFVIQRVLETEGKLTLLDQNRVIRPN
CCCHHHHHHCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCEECCC
KFFRLFATANTVGLGDTSGLYHGTQAINQGQMDRWNLVVALNYLPEATEVEIVTKKVPDL
CEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCC
DPKIVTDMVRVANLTRQGFINGDISTVMSPRTVISWAQNSQIFNDVGFAFRLSFLNKCDE
CHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHEEHHCCCHHHHHHHHHHHHHHHHHCCH
TERVLVAEYYQRVFGKDLPESVAHRG
HHHHHHHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure 
SELPNSHATTLLAAPDTEIDVRETFGIDIDMKVPAFSRADERVPDRDDTYVFDPDTTLA
CCCCCCCCEEEEECCCCCEEEHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCHHH
ILAGFAYNRRVMVQGYHGTGKSTHIEQVAARLNWPCIRINLDAHISRIDLVGRDAIVLRD
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCEEEEEC
GLQVTEFREGLLPWALQTPTALVFDEYDAGRPDVMFVIQRVLETEGKLTLLDQNRVIRPN
CCCHHHHHHCCCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCEECCC
KFFRLFATANTVGLGDTSGLYHGTQAINQGQMDRWNLVVALNYLPEATEVEIVTKKVPDL
CEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCC
DPKIVTDMVRVANLTRQGFINGDISTVMSPRTVISWAQNSQIFNDVGFAFRLSFLNKCDE
CHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHEEHHCCCHHHHHHHHHHHHHHHHHCCH
TERVLVAEYYQRVFGKDLPESVAHRG
HHHHHHHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]