Click here to switch to the map view.

The map label for this gene is era

Identifier: 87199823

GI number: 87199823

Start: 1905065

End: 1905958

Strand: Reverse

Name: era

Synonym: Saro_1806

Alternate gene names: 87199823

Gene position: 1905958-1905065 (Counterclockwise)

Preceding gene: 87199824

Following gene: 87199822

Centisome position: 53.51

GC content: 63.53

Gene sequence:

>894_bases
ATGACAGAAAAATGTGGCCTCGTGGCCGTCCTCGGCGCGCCGAATGCCGGCAAGTCGACCCTCGTCAATGCGCTCGTCGG
CCAGAAGGTGGCGATCGTCTCGGCCAAGGCGCAGACAACGCGCGCGCGGCTCATGGGCATCGCGCTCGAAGGAGAGGCGC
AAATCATCCTTGCGGACACGCCCGGCCTGTTCGAACCGCGCCGCCGGCTCGACCGCGCAATGGTGAGCGCCGCATGGGAC
GGCGCGCAGGAAGCAGACGCGATCCTGCTGGTGGTCGATGCACGCAAGAAGAAGCGTGACTATCTCGAGCCGATCCTCGC
CAGCCTGCGCGAACGGCCGGAACGCAAGATCCTCGTGCTCAACAAGGTCGATTCCACGCCCAAGGAGCCACTGCTGGTGA
TGGCGGAGGCGCTGACCGGGGAAGCGGCATTCGACGAGGTGTTCTTCGTTTCCGCACTGACCGGCGACGGCGTGCCGGAA
CTCAAGCGGCGTCTAGCCGAACTCATGCCCGAAAGCGCGTGGCACTATCCCGAAGACCAGGTCTCGGACGCCAGCGAGCG
CCTGATGGCCGCCGAAATCACGCGCGAACAGCTCTACCGCCAGCTCCACGACGAGCTGCCCTATGACAGTACCGTACGTC
CCGAGAAGTACCTCCATCGCAAGGACGGTTCGATCGAGATCCACCAGCAGATCGTGATTGCCCGCGAGACACAGCGTCCG
ATCGTGCTGGGCAAGGGTGGCGCGAAGATCAAGGCGATCGGAGAGGCCGCACGCAAGGAACTTTCGCAATTGCTCGACAC
CAAGGTGCACCTGTTCCTGCATGTGAAGGTCGACGAGCGCTGGGCCGACGCCAAGGAAATCTACGAGGAAATCGGCCTCG
AATGGGTCAAGTGA

Upstream 100 bases:

>100_bases
GCAGGAAGCGGAAACCGCCGCTGCCCGGGCTTTCATGCAGGCTTATGCCTGACGGCCAGATGGCCTATAGTCTTCCGAGA
TACGGACAGAGAACAAGAAC

Downstream 100 bases:

>100_bases
AGCTCTTCGCGCGCCGCTGCGCCCCAGTACTTCTCGCCCTTGCCGGGCTGGCTCCGGCGGCTACGGTCGCGCGGGAAGCA
CCGCTGGCCGAAGGCGCGCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTEKCGLVAVLGAPNAGKSTLVNALVGQKVAIVSAKAQTTRARLMGIALEGEAQIILADTPGLFEPRRRLDRAMVSAAWD
GAQEADAILLVVDARKKKRDYLEPILASLRERPERKILVLNKVDSTPKEPLLVMAEALTGEAAFDEVFFVSALTGDGVPE
LKRRLAELMPESAWHYPEDQVSDASERLMAAEITREQLYRQLHDELPYDSTVRPEKYLHRKDGSIEIHQQIVIARETQRP
IVLGKGGAKIKAIGEAARKELSQLLDTKVHLFLHVKVDERWADAKEIYEEIGLEWVK

Sequences:

>Translated_297_residues
MTEKCGLVAVLGAPNAGKSTLVNALVGQKVAIVSAKAQTTRARLMGIALEGEAQIILADTPGLFEPRRRLDRAMVSAAWD
GAQEADAILLVVDARKKKRDYLEPILASLRERPERKILVLNKVDSTPKEPLLVMAEALTGEAAFDEVFFVSALTGDGVPE
LKRRLAELMPESAWHYPEDQVSDASERLMAAEITREQLYRQLHDELPYDSTVRPEKYLHRKDGSIEIHQQIVIARETQRP
IVLGKGGAKIKAIGEAARKELSQLLDTKVHLFLHVKVDERWADAKEIYEEIGLEWVK
>Mature_296_residues
TEKCGLVAVLGAPNAGKSTLVNALVGQKVAIVSAKAQTTRARLMGIALEGEAQIILADTPGLFEPRRRLDRAMVSAAWDG
AQEADAILLVVDARKKKRDYLEPILASLRERPERKILVLNKVDSTPKEPLLVMAEALTGEAAFDEVFFVSALTGDGVPEL
KRRLAELMPESAWHYPEDQVSDASERLMAAEITREQLYRQLHDELPYDSTVRPEKYLHRKDGSIEIHQQIVIARETQRPI
VLGKGGAKIKAIGEAARKELSQLLDTKVHLFLHVKVDERWADAKEIYEEIGLEWVK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=29.375, Blast_Score=114, Evalue=8e-26,
Organism=Escherichia coli, GI1788919, Length=290, Percent_Identity=41.3793103448276, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI2367268, Length=168, Percent_Identity=36.3095238095238, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87082120, Length=164, Percent_Identity=30.4878048780488, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24646434, Length=304, Percent_Identity=29.9342105263158, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33115; Mature: 32983

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKCGLVAVLGAPNAGKSTLVNALVGQKVAIVSAKAQTTRARLMGIALEGEAQIILADT
CCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHEEEEECCCEEEEEECC
PGLFEPRRRLDRAMVSAAWDGAQEADAILLVVDARKKKRDYLEPILASLRERPERKILVL
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEE
NKVDSTPKEPLLVMAEALTGEAAFDEVFFVSALTGDGVPELKRRLAELMPESAWHYPEDQ
ECCCCCCCCCHHHHHHHHCCCHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHH
VSDASERLMAAEITREQLYRQLHDELPYDSTVRPEKYLHRKDGSIEIHQQIVIARETQRP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCC
IVLGKGGAKIKAIGEAARKELSQLLDTKVHLFLHVKVDERWADAKEIYEEIGLEWVK
EEEECCCCEEHHHHHHHHHHHHHHHCCEEEEEEEEEECCHHCCHHHHHHHHCCEECC
>Mature Secondary Structure 
TEKCGLVAVLGAPNAGKSTLVNALVGQKVAIVSAKAQTTRARLMGIALEGEAQIILADT
CCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHEEEEECCCEEEEEECC
PGLFEPRRRLDRAMVSAAWDGAQEADAILLVVDARKKKRDYLEPILASLRERPERKILVL
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEE
NKVDSTPKEPLLVMAEALTGEAAFDEVFFVSALTGDGVPELKRRLAELMPESAWHYPEDQ
ECCCCCCCCCHHHHHHHHCCCHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHH
VSDASERLMAAEITREQLYRQLHDELPYDSTVRPEKYLHRKDGSIEIHQQIVIARETQRP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCC
IVLGKGGAKIKAIGEAARKELSQLLDTKVHLFLHVKVDERWADAKEIYEEIGLEWVK
EEEECCCCEEHHHHHHHHHHHHHHHCCEEEEEEEEEECCHHCCHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA