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The map label for this gene is rnc [H]

Identifier: 87199824

GI number: 87199824

Start: 1906007

End: 1906765

Strand: Reverse

Name: rnc [H]

Synonym: Saro_1807

Alternate gene names: 87199824

Gene position: 1906765-1906007 (Counterclockwise)

Preceding gene: 87199825

Following gene: 87199823

Centisome position: 53.54

GC content: 68.12

Gene sequence:

>759_bases
GTGGTCGACCGACGGCAGCGCCAACTGGTTCCTGCCCTGGACCTGGTTCACCGCTGCCCGCTGGAACCGGATCGGGGGCA
CGTTCTGAGCGCGCTTGCCCCGGAGGCCAGCGCCTTCATCGCCGCCCTCACCGGTGCAGCGCCGGCGCGCCCGGAAATCT
GGGCGGAAGCCCTCACCCACGGATCGATGGGCGAGCCGCGCGATTACCAGAGGCTCGAGTTCCTCGGCGACCGTGTCCTT
GGCCTCGCCATAGCGGACTGGCTTCACGAGAAGAGCGATGCCGCCGAAGGCAAGCTTTCGCAGCGCCTCAACGCTCTGGT
CAGTCGCGAGACGTGCGCCGATGTCGCACGAACCATCGGCCTTGCCGGGCACATCCGCCTTGGCAAGCAGGCGCGCGATG
ACGGGGGCGCACAGAGCGACAACATTCTGGGCGACGTGATGGAGGCGCTGATCGGTGCGCTCTTCGTGGAGCGCGGATTC
GAGGCGGCGCGCAAGTTCGTGCGCAAGGCCTGGGAAAAGCCGATGCTCTCGGGCACCGGCCAGCGCAAGCACCCCAAGGC
CGCGCTTCAGGAATGGGCAGCGGGCAACCGCCGCAAGCCGCCGGTCTATACGCTCGTTTCGCGCGAGGGGCCGGACCATG
CCGCCACCTTCACCGTTTCGGTCGAGGTCAAGGGCGTGGGCGAGGCAAGCGCGCGCGGATCTTCCAAGCAGGAAGCGGAA
ACCGCCGCTGCCCGGGCTTTCATGCAGGCTTATGCCTGA

Upstream 100 bases:

>100_bases
ACCGCGACAATTCGATGGATAGCCGCTTCCCGGCAATGGAAGGCGGCGGCATCGGCCTCGTTCCGCAGGAAAACCTCGTC
GGCCGTGCCGCGATCATGAT

Downstream 100 bases:

>100_bases
CGGCCAGATGGCCTATAGTCTTCCGAGATACGGACAGAGAACAAGAACATGACAGAAAAATGTGGCCTCGTGGCCGTCCT
CGGCGCGCCGAATGCCGGCA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MVDRRQRQLVPALDLVHRCPLEPDRGHVLSALAPEASAFIAALTGAAPARPEIWAEALTHGSMGEPRDYQRLEFLGDRVL
GLAIADWLHEKSDAAEGKLSQRLNALVSRETCADVARTIGLAGHIRLGKQARDDGGAQSDNILGDVMEALIGALFVERGF
EAARKFVRKAWEKPMLSGTGQRKHPKAALQEWAAGNRRKPPVYTLVSREGPDHAATFTVSVEVKGVGEASARGSSKQEAE
TAAARAFMQAYA

Sequences:

>Translated_252_residues
MVDRRQRQLVPALDLVHRCPLEPDRGHVLSALAPEASAFIAALTGAAPARPEIWAEALTHGSMGEPRDYQRLEFLGDRVL
GLAIADWLHEKSDAAEGKLSQRLNALVSRETCADVARTIGLAGHIRLGKQARDDGGAQSDNILGDVMEALIGALFVERGF
EAARKFVRKAWEKPMLSGTGQRKHPKAALQEWAAGNRRKPPVYTLVSREGPDHAATFTVSVEVKGVGEASARGSSKQEAE
TAAARAFMQAYA
>Mature_252_residues
MVDRRQRQLVPALDLVHRCPLEPDRGHVLSALAPEASAFIAALTGAAPARPEIWAEALTHGSMGEPRDYQRLEFLGDRVL
GLAIADWLHEKSDAAEGKLSQRLNALVSRETCADVARTIGLAGHIRLGKQARDDGGAQSDNILGDVMEALIGALFVERGF
EAARKFVRKAWEKPMLSGTGQRKHPKAALQEWAAGNRRKPPVYTLVSREGPDHAATFTVSVEVKGVGEASARGSSKQEAE
TAAARAFMQAYA

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI155030234, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788920, Length=198, Percent_Identity=32.8282828282828, Blast_Score=98, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17506883, Length=184, Percent_Identity=32.0652173913043, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193202651, Length=184, Percent_Identity=32.0652173913043, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137682, Length=202, Percent_Identity=28.7128712871287, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 27222; Mature: 27222

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDRRQRQLVPALDLVHRCPLEPDRGHVLSALAPEASAFIAALTGAAPARPEIWAEALTH
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHC
GSMGEPRDYQRLEFLGDRVLGLAIADWLHEKSDAAEGKLSQRLNALVSRETCADVARTIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGHIRLGKQARDDGGAQSDNILGDVMEALIGALFVERGFEAARKFVRKAWEKPMLSGTG
HHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QRKHPKAALQEWAAGNRRKPPVYTLVSREGPDHAATFTVSVEVKGVGEASARGSSKQEAE
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCHHCCCCCHHHHH
TAAARAFMQAYA
HHHHHHHHHHCC
>Mature Secondary Structure
MVDRRQRQLVPALDLVHRCPLEPDRGHVLSALAPEASAFIAALTGAAPARPEIWAEALTH
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHC
GSMGEPRDYQRLEFLGDRVLGLAIADWLHEKSDAAEGKLSQRLNALVSRETCADVARTIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGHIRLGKQARDDGGAQSDNILGDVMEALIGALFVERGFEAARKFVRKAWEKPMLSGTG
HHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QRKHPKAALQEWAAGNRRKPPVYTLVSREGPDHAATFTVSVEVKGVGEASARGSSKQEAE
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCHHCCCCCHHHHH
TAAARAFMQAYA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA