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The map label for this gene is mraY

Identifier: 87199152

GI number: 87199152

Start: 1175335

End: 1176399

Strand: Direct

Name: mraY

Synonym: Saro_1130

Alternate gene names: 87199152

Gene position: 1175335-1176399 (Clockwise)

Preceding gene: 87199151

Following gene: 87199153

Centisome position: 33.0

GC content: 65.54

Gene sequence:

>1065_bases
ATGCTCTACCTGCTGGCGCAATGGCTGCACTTTGAGGGGTTCAGCAACCTCATCCGATACCAGACGTTCCGCGCCGGCGC
GACGCTGCTGACCGCGCTGGTGATCGGCCTGATCATCGGGCCCCGGTTCATCAACATGCTCCGCGTCCGCCAGGGCAAGG
GCCAGCCGATCCGCGAGGACGGCCCGCAGTCGCACCTCGCCAAGCGTGGCACGCCGACCATGGGCGGCCTGATGATCGTC
ACGGCGCTCACGCTGTCGCTGCTCCTGTGGATGGACGTCACCAGCAGGCTCGTCTGGGCCTGCGCCGTCGTCACGCTCGG
CTTTGGGCTGATCGGCTTCCTCGACGACTACGACAAGGTGACGAAGTACGCGCACAAGGGCGTGCCCGCCAAGGTGCGGC
TGGCCGGGGAATTCGTCGTTGCAGCCTTTGCCGCGTGGCTCGCGGTGGGCGAGACGAACCTCTACGTGCCGGTGTTCAGC
AACCTCTACGTCCCGCTCGGGCCGTTCTACTATCTCTTCGCGATCTTCGTGATCGTGGGTGCCGGCAATGCCGTGAACCT
TACCGACGGCCTCGACGGGCTTGCCATCATGCCCGTCATCATCGCGGCCGGCACCTTTGCGATCATTGCCTATCTCGCGG
GCCGCTATGACTTCGCGACGTATCTCGGCATCCCGCATGTGAAGGGCGCGGGCGAACTTGCGATCTTCTGCGCGGCGATG
ATGGGGGCGGGGCTGGCCTTCCTCTGGTTCAACGCGCCACCGGCGGCGGTGTTCATGGGCGATACCGGCAGTCTTGCGCT
GGGCGGCGCGTTGGGCGTGATCGCGGTCGCCGCGCACCACGAGATCGTGCTGGCCATTGTCGGCGGGCTGTTCGTGATGG
AGGCGGTCTCGGTGATCGTCCAGGTCGCGGTCTACAAGCGCACTGGCAAGCGGGTGTTCCGCATGGCGCCGATCCACCAC
CACTTCGAGCAGCTCGGCTGGAAGGAATCGACCGTCGTCATCCGCTTCTGGATCGTGTCGATCGTGCTCGCGCTGATCGG
CCTTGCGACGCTGAAGGTTCGATGA

Upstream 100 bases:

>100_bases
TGCAGATGGCGTGCGCGGGGGTGACGCCATCCTCGTCAAGGGGTCGAATTCGGTCGGGCTGGGTGCGCTGGTGCGCTCGC
TCACCGGCAAGGAACGTTGA

Downstream 100 bases:

>100_bases
TCGTCTCGCGCGCCTTTGCCGGAAAGCGTTACGCGGTTCTCGGTCTCGCGCGCTCGGGCCTTGCCAGCGTCGAAAGCCTG
CTGGCCGGCGGCGCTGACGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MLYLLAQWLHFEGFSNLIRYQTFRAGATLLTALVIGLIIGPRFINMLRVRQGKGQPIREDGPQSHLAKRGTPTMGGLMIV
TALTLSLLLWMDVTSRLVWACAVVTLGFGLIGFLDDYDKVTKYAHKGVPAKVRLAGEFVVAAFAAWLAVGETNLYVPVFS
NLYVPLGPFYYLFAIFVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRYDFATYLGIPHVKGAGELAIFCAAM
MGAGLAFLWFNAPPAAVFMGDTGSLALGGALGVIAVAAHHEIVLAIVGGLFVMEAVSVIVQVAVYKRTGKRVFRMAPIHH
HFEQLGWKESTVVIRFWIVSIVLALIGLATLKVR

Sequences:

>Translated_354_residues
MLYLLAQWLHFEGFSNLIRYQTFRAGATLLTALVIGLIIGPRFINMLRVRQGKGQPIREDGPQSHLAKRGTPTMGGLMIV
TALTLSLLLWMDVTSRLVWACAVVTLGFGLIGFLDDYDKVTKYAHKGVPAKVRLAGEFVVAAFAAWLAVGETNLYVPVFS
NLYVPLGPFYYLFAIFVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRYDFATYLGIPHVKGAGELAIFCAAM
MGAGLAFLWFNAPPAAVFMGDTGSLALGGALGVIAVAAHHEIVLAIVGGLFVMEAVSVIVQVAVYKRTGKRVFRMAPIHH
HFEQLGWKESTVVIRFWIVSIVLALIGLATLKVR
>Mature_354_residues
MLYLLAQWLHFEGFSNLIRYQTFRAGATLLTALVIGLIIGPRFINMLRVRQGKGQPIREDGPQSHLAKRGTPTMGGLMIV
TALTLSLLLWMDVTSRLVWACAVVTLGFGLIGFLDDYDKVTKYAHKGVPAKVRLAGEFVVAAFAAWLAVGETNLYVPVFS
NLYVPLGPFYYLFAIFVIVGAGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRYDFATYLGIPHVKGAGELAIFCAAM
MGAGLAFLWFNAPPAAVFMGDTGSLALGGALGVIAVAAHHEIVLAIVGGLFVMEAVSVIVQVAVYKRTGKRVFRMAPIHH
HFEQLGWKESTVVIRFWIVSIVLALIGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=362, Percent_Identity=55.524861878453, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_NOVAD (Q2G998)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496409.1
- STRING:   Q2G998
- GeneID:   3916426
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1130
- NMPDR:   fig|48935.1.peg.662
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- PhylomeDB:   Q2G998
- ProtClustDB:   PRK00108
- BioCyc:   NARO279238:SARO_1130-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38153; Mature: 38153

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13abbdbc)-; HASH(0x14be764c)-; HASH(0x15352190)-; HASH(0x153a7768)-; HASH(0x153a7594)-; HASH(0x1539ef7c)-; HASH(0x1539eef8)-; HASH(0x153a7b18)-; HASH(0x153a12c4)-; HASH(0x153a73e4)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLLAQWLHFEGFSNLIRYQTFRAGATLLTALVIGLIIGPRFINMLRVRQGKGQPIRED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKRGTPTMGGLMIVTALTLSLLLWMDVTSRLVWACAVVTLGFGLIGFLDDYDKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKYAHKGVPAKVRLAGEFVVAAFAAWLAVGETNLYVPVFSNLYVPLGPFYYLFAIFVIVG
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
AGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRYDFATYLGIPHVKGAGELAIFCAAM
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
MGAGLAFLWFNAPPAAVFMGDTGSLALGGALGVIAVAAHHEIVLAIVGGLFVMEAVSVIV
HHCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVAVYKRTGKRVFRMAPIHHHFEQLGWKESTVVIRFWIVSIVLALIGLATLKVR
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYLLAQWLHFEGFSNLIRYQTFRAGATLLTALVIGLIIGPRFINMLRVRQGKGQPIRED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQSHLAKRGTPTMGGLMIVTALTLSLLLWMDVTSRLVWACAVVTLGFGLIGFLDDYDKV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKYAHKGVPAKVRLAGEFVVAAFAAWLAVGETNLYVPVFSNLYVPLGPFYYLFAIFVIVG
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
AGNAVNLTDGLDGLAIMPVIIAAGTFAIIAYLAGRYDFATYLGIPHVKGAGELAIFCAAM
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
MGAGLAFLWFNAPPAAVFMGDTGSLALGGALGVIAVAAHHEIVLAIVGGLFVMEAVSVIV
HHCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVAVYKRTGKRVFRMAPIHHHFEQLGWKESTVVIRFWIVSIVLALIGLATLKVR
HHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA