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The map label for this gene is aatC [H]

Identifier: 87198526

GI number: 87198526

Start: 543116

End: 544357

Strand: Direct

Name: aatC [H]

Synonym: Saro_0501

Alternate gene names: 87198526

Gene position: 543116-544357 (Clockwise)

Preceding gene: 87198522

Following gene: 87198527

Centisome position: 15.25

GC content: 64.01

Gene sequence:

>1242_bases
TTGCGGCGATCCTGCCGCGTTCATTCGACGAGTAACCAAACCGTGGACGAAGAATTCTACCGCATGAAGCGCCTGCCGCC
CTACGTCATTGCCGAAGTCAACGGCATGCGGGCCGCCGCGCGCGCCGCCGGTAGGGACATCATCGACCTCGGCATGGGCA
ACCCGGACCTGCCGCCGCCCCAGCACGTGATCGACAAGCTGTGCGAAGTGGCGCAGAAGCCCGATGCGCACGGCTATTCG
GCATCCTCGGGCATCCCGGGCGTGCGCAAGGCCCAGGCCAACTACTATGGCCGCCGCTTCAACGTAGATCTCGATCCCGA
GACCGAAGTGGTGATGACGATGGGTTCGAAGGAGGGCCTGGCCAGCCTCGCAACCGCGATCACCGCGCCCGGGGACGTCG
TGCTGGCCCCCAATCCCAGCTATCCGATCCACACCTTCGGCTTCATCATAGCCGGGGCGACGATCCGTTCGGTGCCGACC
ACGCCTGACGAGCGCTATTGGGATTCGCTCGACCGCGCGATGAAGTATTCGGTGCCGCGCCCCTCGATCCTTATCGTCAA
CTATCCGTCCAACCCGACTGCGGAGACGGTAGACCTCGCCTTCTACGAACGCCTTGTTGCCTGGGCGAAGGAGAACAAGG
TCTGGATCCTGTCCGACCTCGCCTATTCCGAACTGTACTATGACGGCAATCCGACCCGCTCCATCCTCGAGGTTCCGGGT
GCGAAGGATGTCGCGGTCGAGTTCACCTCGATGTCCAAGACCTTCTCGATGGCAGGCTGGCGCGTTGGCTTTGCGGTTGG
CAACCAGCGCCTTATCGCGGCGCTTAAGCGCGTGAAATCCTACCTCGATTACGGCGCGTTCACGCCGATCCAGGCTGCCG
CCTGCGCAGCGCTGAACGGCCCGCAGGACATCGTCGTCAAGAACCGCGAACTCTACCAGAAGCGCCGCGACGTGATGGTG
GAGGCATTCGGCCGCGCCGGATGGGAAATCCCCAGCCCCAGCGCATCGATGTTCGCGTGGGCGCCGTTGCCGCCGGCACT
GACCCATCTGGGCAGCCTCGAGTTCTCGAAGCAGCTTCTTACCCATGCCGAAGTCGCGGTTGCCCCGGGCGTTGGCTATG
GCGAGGACGGCGAAGGTTTCGTGCGCATCGCGATGGTCGAGAACGAGCAGCGCCTTCGCCAGGCGGCGCGCAACATCAAG
CGTTACCTGCAAAGCATGGGCGTCAACGCCTCGGCGGCCTGA

Upstream 100 bases:

>100_bases
CTATACACGTCATGTTACACCTTGTTAGCCCCGTCTTGTCCGGTGCGACGCCCGTCGAGAGCAAGGTTTCCACCGCTGGC
CAATTGGCGTAAGGGCCGGA

Downstream 100 bases:

>100_bases
AGCCCTTGGCAGCATGACAGGAAAACGGCCCTTTCCGCACCTGCGGGGAGGGCCTTTCGCTTTACGGCGATCGGTCAATA
GAGGAAGCTGGACCCCGCCG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MRRSCRVHSTSNQTVDEEFYRMKRLPPYVIAEVNGMRAAARAAGRDIIDLGMGNPDLPPPQHVIDKLCEVAQKPDAHGYS
ASSGIPGVRKAQANYYGRRFNVDLDPETEVVMTMGSKEGLASLATAITAPGDVVLAPNPSYPIHTFGFIIAGATIRSVPT
TPDERYWDSLDRAMKYSVPRPSILIVNYPSNPTAETVDLAFYERLVAWAKENKVWILSDLAYSELYYDGNPTRSILEVPG
AKDVAVEFTSMSKTFSMAGWRVGFAVGNQRLIAALKRVKSYLDYGAFTPIQAAACAALNGPQDIVVKNRELYQKRRDVMV
EAFGRAGWEIPSPSASMFAWAPLPPALTHLGSLEFSKQLLTHAEVAVAPGVGYGEDGEGFVRIAMVENEQRLRQAARNIK
RYLQSMGVNASAA

Sequences:

>Translated_413_residues
MRRSCRVHSTSNQTVDEEFYRMKRLPPYVIAEVNGMRAAARAAGRDIIDLGMGNPDLPPPQHVIDKLCEVAQKPDAHGYS
ASSGIPGVRKAQANYYGRRFNVDLDPETEVVMTMGSKEGLASLATAITAPGDVVLAPNPSYPIHTFGFIIAGATIRSVPT
TPDERYWDSLDRAMKYSVPRPSILIVNYPSNPTAETVDLAFYERLVAWAKENKVWILSDLAYSELYYDGNPTRSILEVPG
AKDVAVEFTSMSKTFSMAGWRVGFAVGNQRLIAALKRVKSYLDYGAFTPIQAAACAALNGPQDIVVKNRELYQKRRDVMV
EAFGRAGWEIPSPSASMFAWAPLPPALTHLGSLEFSKQLLTHAEVAVAPGVGYGEDGEGFVRIAMVENEQRLRQAARNIK
RYLQSMGVNASAA
>Mature_413_residues
MRRSCRVHSTSNQTVDEEFYRMKRLPPYVIAEVNGMRAAARAAGRDIIDLGMGNPDLPPPQHVIDKLCEVAQKPDAHGYS
ASSGIPGVRKAQANYYGRRFNVDLDPETEVVMTMGSKEGLASLATAITAPGDVVLAPNPSYPIHTFGFIIAGATIRSVPT
TPDERYWDSLDRAMKYSVPRPSILIVNYPSNPTAETVDLAFYERLVAWAKENKVWILSDLAYSELYYDGNPTRSILEVPG
AKDVAVEFTSMSKTFSMAGWRVGFAVGNQRLIAALKRVKSYLDYGAFTPIQAAACAALNGPQDIVVKNRELYQKRRDVMV
EAFGRAGWEIPSPSASMFAWAPLPPALTHLGSLEFSKQLLTHAEVAVAPGVGYGEDGEGFVRIAMVENEQRLRQAARNIK
RYLQSMGVNASAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=25.3196930946292, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=25.3196930946292, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=22.7848101265823, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=22.7848101265823, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI169881281, Length=385, Percent_Identity=21.5584415584416, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=20.5194805194805, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=50.8905852417303, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=25.5434782608696, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788627, Length=285, Percent_Identity=26.3157894736842, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788332, Length=232, Percent_Identity=26.7241379310345, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=267, Percent_Identity=28.0898876404494, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=267, Percent_Identity=28.0898876404494, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=393, Percent_Identity=21.6284987277354, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=394, Percent_Identity=22.0812182741117, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=22.4806201550388, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=23.1428571428571, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=27.0618556701031, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=27.0618556701031, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=27.0618556701031, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=27.0618556701031, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45551451, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641770, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641760, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641768, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641766, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641764, Length=381, Percent_Identity=23.3595800524934, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45308; Mature: 45308

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSCRVHSTSNQTVDEEFYRMKRLPPYVIAEVNGMRAAARAAGRDIIDLGMGNPDLPPP
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCCCCH
QHVIDKLCEVAQKPDAHGYSASSGIPGVRKAQANYYGRRFNVDLDPETEVVMTMGSKEGL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHH
ASLATAITAPGDVVLAPNPSYPIHTFGFIIAGATIRSVPTTPDERYWDSLDRAMKYSVPR
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHCCCCC
PSILIVNYPSNPTAETVDLAFYERLVAWAKENKVWILSDLAYSELYYDGNPTRSILEVPG
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHEEECCCCCCHHEECCC
AKDVAVEFTSMSKTFSMAGWRVGFAVGNQRLIAALKRVKSYLDYGAFTPIQAAACAALNG
CCCEEEEEHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PQDIVVKNRELYQKRRDVMVEAFGRAGWEIPSPSASMFAWAPLPPALTHLGSLEFSKQLL
CHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHH
THAEVAVAPGVGYGEDGEGFVRIAMVENEQRLRQAARNIKRYLQSMGVNASAA
HHHHHEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRRSCRVHSTSNQTVDEEFYRMKRLPPYVIAEVNGMRAAARAAGRDIIDLGMGNPDLPPP
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCCCCCH
QHVIDKLCEVAQKPDAHGYSASSGIPGVRKAQANYYGRRFNVDLDPETEVVMTMGSKEGL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCEEEEECCCHHH
ASLATAITAPGDVVLAPNPSYPIHTFGFIIAGATIRSVPTTPDERYWDSLDRAMKYSVPR
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHCCCCC
PSILIVNYPSNPTAETVDLAFYERLVAWAKENKVWILSDLAYSELYYDGNPTRSILEVPG
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHEEECCCCCCHHEECCC
AKDVAVEFTSMSKTFSMAGWRVGFAVGNQRLIAALKRVKSYLDYGAFTPIQAAACAALNG
CCCEEEEEHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PQDIVVKNRELYQKRRDVMVEAFGRAGWEIPSPSASMFAWAPLPPALTHLGSLEFSKQLL
CHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHH
THAEVAVAPGVGYGEDGEGFVRIAMVENEQRLRQAARNIKRYLQSMGVNASAA
HHHHHEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]