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The map label for this gene is mmgC [H]

Identifier: 87198307

GI number: 87198307

Start: 302388

End: 303689

Strand: Direct

Name: mmgC [H]

Synonym: Saro_0282

Alternate gene names: 87198307

Gene position: 302388-303689 (Clockwise)

Preceding gene: 87198306

Following gene: 87198315

Centisome position: 8.49

GC content: 66.67

Gene sequence:

>1302_bases
ATGGACTTCGACATTCCCGCCGATCTTGCCGCCTATGTCGCCGAACTCGACGCCTTCATCGAGGCCGAGATCAAGCCGCT
CGAGGAGGCGGACGACAACATCCGCTTCTTCGATCACCGCCGCGAATGGGCGCGGACCGATTTCGAGAACGGCGGGTTGC
CGCGCCACGAATGGGAGGCCCTGCTGGTCGAGGCGACGCGCCGCGCGGATGCCGCCGGCCACTGGCGCTTTTCCGCGCCC
AAGAAGTACGGCGGCAAGGACGGCACCAACCTGTGGATGGCGGTGATCCGCGATCACTTCGCCGCCAGGGGGCTTGGGCT
GCACAACGATCTCCAGAACGAACACTCGATCGTCGGCAACTTCCCCTTCGTGAACATGTTCGAGCATTTCGGCACGCCCG
AGCAGCAGGACGAATTCATCAACGGCGGCTTTGCCAGAACCCGCCGCACCGCCTTCGGCCTGACCGAGCCGCGCCACGGG
TCGGATGCCACCCACATGGAAACGCGGGCCGTGCCCGAAACGCGCGACGGGGTTCCCGGCTGGCGCATCGATGGCGAGAA
GATGTGGACGACGGGAATGCACGTCGCCACCCACTGCGCCACGTTCGCGCGCACCAGCGGCGCGGACGGCGATGCGCGGG
GCATCACCTGCTTCCTCGTGCCCAACCCGACCGAAGGGCTGGTGATCGAGGAATACCTGTGGACGTTCAACATGCCCACC
GACCACCCGCGCGTCTCGTTCACCAATGTCTGGGTGCCGGACAGCGCGATCCTCGGGCCGGTCGGTGGCGGGCTCGCCAT
CGCGCAAAGCTTCGTCCACCAGAACCGCATCCGCCAGGCCGCTTCGTCGCTGGGAGCGGCCACGTTCTGCGTCGAGGAAT
CGGTGCGCTATGCGCGCGAGCGCAAGCCCTTCGGCGAGGAGCTGGCACGCAACCAGGCGATCCAGTTCCCGCTCGTCGAA
CTGGCCACCCAGTGCGAGATGCTGCGCCTGCTGATCCGCAAGACCGCCTGGGACATGGACCGCCTCGAAGCCGAGGAAGG
CGGGCACAAGCGGATCGAGCGCGAGCTGTCGGACAAGGTGTCGATGTGCAACTACTGGGCGAACCGGCTGGTCTGCGAGG
CGGCGGACCGGGCGATGCAGGTCCACGGCGGCATCGGCTATTCGCGGCACAAGCCGTTCGAACACATCTACCGCCACCAC
CGCCGCTACCGCATCACCGAAGGCGCGGAGGAAATCCAGATGCGCAAGGTCGGCGCCTTCCTGTTCGGTTACCTCGGGCC
GAGGAGGGGCATGTTCGGGTAG

Upstream 100 bases:

>100_bases
TGCTTGCCGCGCTGCGCCGCCGCGCGCTGTCCACCCTTTCCGCCGACATGCCCAAATATCCCGCGCTGGCACGCGCACGC
ACGCTCTGGGAGCACCGCTG

Downstream 100 bases:

>100_bases
CGGCGCGCAGGCGCCACCCGGACGCGGGACAGGATCAGTCGAACAGCCTGTCGAACCAGGTCTTCCGGGCCGTGGTATCG
GCGAACAGACCCTCGACCAG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MDFDIPADLAAYVAELDAFIEAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEALLVEATRRADAAGHWRFSAP
KKYGGKDGTNLWMAVIRDHFAARGLGLHNDLQNEHSIVGNFPFVNMFEHFGTPEQQDEFINGGFARTRRTAFGLTEPRHG
SDATHMETRAVPETRDGVPGWRIDGEKMWTTGMHVATHCATFARTSGADGDARGITCFLVPNPTEGLVIEEYLWTFNMPT
DHPRVSFTNVWVPDSAILGPVGGGLAIAQSFVHQNRIRQAASSLGAATFCVEESVRYARERKPFGEELARNQAIQFPLVE
LATQCEMLRLLIRKTAWDMDRLEAEEGGHKRIERELSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHH
RRYRITEGAEEIQMRKVGAFLFGYLGPRRGMFG

Sequences:

>Translated_433_residues
MDFDIPADLAAYVAELDAFIEAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEALLVEATRRADAAGHWRFSAP
KKYGGKDGTNLWMAVIRDHFAARGLGLHNDLQNEHSIVGNFPFVNMFEHFGTPEQQDEFINGGFARTRRTAFGLTEPRHG
SDATHMETRAVPETRDGVPGWRIDGEKMWTTGMHVATHCATFARTSGADGDARGITCFLVPNPTEGLVIEEYLWTFNMPT
DHPRVSFTNVWVPDSAILGPVGGGLAIAQSFVHQNRIRQAASSLGAATFCVEESVRYARERKPFGEELARNQAIQFPLVE
LATQCEMLRLLIRKTAWDMDRLEAEEGGHKRIERELSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHH
RRYRITEGAEEIQMRKVGAFLFGYLGPRRGMFG
>Mature_433_residues
MDFDIPADLAAYVAELDAFIEAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEALLVEATRRADAAGHWRFSAP
KKYGGKDGTNLWMAVIRDHFAARGLGLHNDLQNEHSIVGNFPFVNMFEHFGTPEQQDEFINGGFARTRRTAFGLTEPRHG
SDATHMETRAVPETRDGVPGWRIDGEKMWTTGMHVATHCATFARTSGADGDARGITCFLVPNPTEGLVIEEYLWTFNMPT
DHPRVSFTNVWVPDSAILGPVGGGLAIAQSFVHQNRIRQAASSLGAATFCVEESVRYARERKPFGEELARNQAIQFPLVE
LATQCEMLRLLIRKTAWDMDRLEAEEGGHKRIERELSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHH
RRYRITEGAEEIQMRKVGAFLFGYLGPRRGMFG

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=28.3333333333333, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4501859, Length=343, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI187960098, Length=355, Percent_Identity=27.3239436619718, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4557231, Length=355, Percent_Identity=27.3239436619718, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI7656849, Length=293, Percent_Identity=29.3515358361775, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=26.6149870801034, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI21361497, Length=394, Percent_Identity=24.8730964467005, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=406, Percent_Identity=24.6305418719212, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI76496475, Length=406, Percent_Identity=24.6305418719212, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI38505218, Length=312, Percent_Identity=25.3205128205128, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI211971008, Length=416, Percent_Identity=23.7980769230769, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI48976061, Length=416, Percent_Identity=23.7980769230769, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=22.8813559322034, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226958412, Length=354, Percent_Identity=22.8813559322034, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503943, Length=199, Percent_Identity=30.1507537688442, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7669494, Length=199, Percent_Identity=30.1507537688442, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=24.869109947644, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=25.5263157894737, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=27.6712328767123, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17534899, Length=362, Percent_Identity=28.7292817679558, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17570075, Length=418, Percent_Identity=24.8803827751196, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=351, Percent_Identity=26.7806267806268, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=353, Percent_Identity=27.4787535410765, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=293, Percent_Identity=28.3276450511945, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=286, Percent_Identity=28.6713286713287, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=27.3408239700375, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=359, Percent_Identity=26.1838440111421, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=292, Percent_Identity=26.3698630136986, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=347, Percent_Identity=23.9193083573487, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=244, Percent_Identity=29.5081967213115, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=246, Percent_Identity=26.4227642276423, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=299, Percent_Identity=25.0836120401338, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=184, Percent_Identity=29.8913043478261, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=273, Percent_Identity=24.9084249084249, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666513, Length=329, Percent_Identity=30.3951367781155, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24660351, Length=344, Percent_Identity=29.3604651162791, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646207, Length=361, Percent_Identity=29.9168975069252, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21356377, Length=299, Percent_Identity=28.4280936454849, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI281363737, Length=406, Percent_Identity=25.8620689655172, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21355753, Length=405, Percent_Identity=25.1851851851852, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920834, Length=203, Percent_Identity=33.0049261083744, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 49149; Mature: 49149

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDIPADLAAYVAELDAFIEAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHH
LLVEATRRADAAGHWRFSAPKKYGGKDGTNLWMAVIRDHFAARGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCEECC
FPFVNMFEHFGTPEQQDEFINGGFARTRRTAFGLTEPRHGSDATHMETRAVPETRDGVPG
CCHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
WRIDGEKMWTTGMHVATHCATFARTSGADGDARGITCFLVPNPTEGLVIEEYLWTFNMPT
CEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEHHHHEECCCC
DHPRVSFTNVWVPDSAILGPVGGGLAIAQSFVHQNRIRQAASSLGAATFCVEESVRYARE
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
RKPFGEELARNQAIQFPLVELATQCEMLRLLIRKTAWDMDRLEAEEGGHKRIERELSDKV
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHH
SMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGAEEIQMRKVGAF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEECCCCHHHHHHHHHHHH
LFGYLGPRRGMFG
HHHHHCCCCCCCC
>Mature Secondary Structure
MDFDIPADLAAYVAELDAFIEAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHH
LLVEATRRADAAGHWRFSAPKKYGGKDGTNLWMAVIRDHFAARGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCEECC
FPFVNMFEHFGTPEQQDEFINGGFARTRRTAFGLTEPRHGSDATHMETRAVPETRDGVPG
CCHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
WRIDGEKMWTTGMHVATHCATFARTSGADGDARGITCFLVPNPTEGLVIEEYLWTFNMPT
CEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEHHHHEECCCC
DHPRVSFTNVWVPDSAILGPVGGGLAIAQSFVHQNRIRQAASSLGAATFCVEESVRYARE
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
RKPFGEELARNQAIQFPLVELATQCEMLRLLIRKTAWDMDRLEAEEGGHKRIERELSDKV
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHH
SMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGAEEIQMRKVGAF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEECCCCHHHHHHHHHHHH
LFGYLGPRRGMFG
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]