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The map label for this gene is htpG

Identifier: 86751790

GI number: 86751790

Start: 5309442

End: 5311328

Strand: Reverse

Name: htpG

Synonym: RPB_4692

Alternate gene names: 86751790

Gene position: 5311328-5309442 (Counterclockwise)

Preceding gene: 86751791

Following gene: 86751789

Centisome position: 99.62

GC content: 65.02

Gene sequence:

>1887_bases
ATGACCACGATTGATACCGCCAGCGAGACGAAGCCGTTCCAGGCCGAAGTGGCCGAGCTTTTGAACCTGATGGTGCACTC
GGTCTATTCCGAGACCGACATCTTCCTGCGCGAGCTGATCTCCAACGCCTCCGACGCGCTCGACAAGCTGCGCTACGAAT
CGATCGCCAATCCGGCGCTGATGGCGGACGGCGGCGAGCCGAAGATCCGGATCGTGCCGAAGAAAGCCCCGGATACGCTG
ACCGTGATCGACAACGGCATCGGCATGGACCGCCAGGAGCTGATCGACAATCTCGGCACCATTGCCAAATCCGGCACCAA
ATCGTTTCTGACCAAATTGACCGAGGCCAAGGACGGTGCCGGCCTGATCGGCCAGTTCGGCGTCGGCTTCTACGCCGCCT
TCATGGTCGCCGACAGCATCACCGTCACCAGCCGCCGCGCCGGCTCGGCCGAGGCCTGGACCTGGTCGTCGTCGGGCGGC
GCCGGCTTCGAGATCGCGCCGGCCTCCGAAGAGGCCGCGGCCCGTATCGAGCGCGGCACCGAGATCGTGCTGCATCTGAA
GCCGGATGCGGCGAAATATCTCGAGGCCTATCAGATCGAGCGGATCGTCAGCGAGTACTCCGACAACATCCAGTTCCCGA
TCGAGCTGGTGCCCGAAGACGGCGAGCCGCGCCAGATCAATTCGGCCAGCGCGTTGTGGCAGCGCTCGAAGTCCGAACTG
ACCGAAGAGGACTACAAGCAGGCCTACAAGCAGGTCGCCGGCGCCTTCGACGAGCCGGCGATGACGCTGCATTATCGCGC
CGAAGGCCGGCAGTCCTATGCGGTGCTGCTGTTCGCACCCTCGACGAAGCCGTTCGATCTGTTCGAGCCGGAGCGCAAGG
GCCGCGTCAAGCTGTATGTCCGCCGCGTCTTCATCACCGCGGATGCCGATCTGTTGCCGCCTTATCTGCGCTTCCTGCGC
GGCGTGATCGATTCGGAGGACCTGCCGCTGAATCTGTCGCGCGAGATGCTGCAGAACAATCCGCAGCTGGCGCAGATCCG
CAAGGCGGTCACCGGCAAGGTGATCGGCGAACTCGACAGCCTCGCCGACAAGCAGCCCGAGCAATTCGCCAAGATCTGGG
ACGCGTTCGGCCCGGTGATCAAGGAAGGTCTCTACGAGGATTACGAGCGCCGCGAGAAGCTGCTGTCGCTGGCGCGCTTC
ACCACCACCGCCGGCGAGAAGCGCTCGCTCGCGCAATATGTCGAGGCGATGAAGGAGAACCAGACCGAGATCTACTATCT
GGTCGGCGATTCGCTGGACCGCCTGAAGGCGAACCCGAAGCTCGAATCGGCCGCCGCGCGCGGCATCGAGGTGCTGCTGC
TGACCGACGCGGTCGATGCGTTCTGGACTTCGGGCGGGCTCGATTTCGGCGGCAAGCCACTGAAGTCGCTGAGCCAGGGC
GAGGTGAATTTCGACCTGATCCCGAAGCTCGACGCCGACAAGGCCGAGGACAAGCCGGACGAGGCCAAGGCCGACGAAGC
CACCGTGATCGCCGTGATCAAGGATGCGCTCGGCGATCGCGTCAGCGACGTGAAGGCGTCGCAGCGGCTGACCGCGAGCG
CGTCCTGCCTGGTCGCCGGCGGCTTCGGGCCCGATCGCGAGCTGGAGAAGATGCTGGCGCGCGCCAACAAGGGCGCCGCC
ACCAAGCCGGTGCTCGAGATCAATCTCGGCCACCCGCTGGTCGCAGCGTTGGCGGATACCAAAGCCGACAAGGCCGACGC
CACCGACCTGTCGTTCCTGCTGCTGGAACAGGCGCAGATCCTCGACGGCGAATTGCCCGAAGACCCCGCCGCCTTCGCCG
GCCGCCTCAACCGGCTGGTGCTGCGCGGCGTTGTTGCGCATGGTTAG

Upstream 100 bases:

>100_bases
GGCGCGCTGATTTGGAGGCAATCACCGTCTTGCCATCGTGCGCCCGCGCGCTATATCCGAGCTTTCCCCCTTCACCCTTG
TTCAGGATCGAGCGTTCCTC

Downstream 100 bases:

>100_bases
CGCCTGACTAACAAACAGGGTTACCGGATTTTTAATCCCTGGGTTGCACACTGGCCGGCATCTGACGCCGACCAGTTGTG
TGAACCCCATGCGTCTTTTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTTIDTASETKPFQAEVAELLNLMVHSVYSETDIFLRELISNASDALDKLRYESIANPALMADGGEPKIRIVPKKAPDTL
TVIDNGIGMDRQELIDNLGTIAKSGTKSFLTKLTEAKDGAGLIGQFGVGFYAAFMVADSITVTSRRAGSAEAWTWSSSGG
AGFEIAPASEEAAARIERGTEIVLHLKPDAAKYLEAYQIERIVSEYSDNIQFPIELVPEDGEPRQINSASALWQRSKSEL
TEEDYKQAYKQVAGAFDEPAMTLHYRAEGRQSYAVLLFAPSTKPFDLFEPERKGRVKLYVRRVFITADADLLPPYLRFLR
GVIDSEDLPLNLSREMLQNNPQLAQIRKAVTGKVIGELDSLADKQPEQFAKIWDAFGPVIKEGLYEDYERREKLLSLARF
TTTAGEKRSLAQYVEAMKENQTEIYYLVGDSLDRLKANPKLESAAARGIEVLLLTDAVDAFWTSGGLDFGGKPLKSLSQG
EVNFDLIPKLDADKAEDKPDEAKADEATVIAVIKDALGDRVSDVKASQRLTASASCLVAGGFGPDRELEKMLARANKGAA
TKPVLEINLGHPLVAALADTKADKADATDLSFLLLEQAQILDGELPEDPAAFAGRLNRLVLRGVVAHG

Sequences:

>Translated_628_residues
MTTIDTASETKPFQAEVAELLNLMVHSVYSETDIFLRELISNASDALDKLRYESIANPALMADGGEPKIRIVPKKAPDTL
TVIDNGIGMDRQELIDNLGTIAKSGTKSFLTKLTEAKDGAGLIGQFGVGFYAAFMVADSITVTSRRAGSAEAWTWSSSGG
AGFEIAPASEEAAARIERGTEIVLHLKPDAAKYLEAYQIERIVSEYSDNIQFPIELVPEDGEPRQINSASALWQRSKSEL
TEEDYKQAYKQVAGAFDEPAMTLHYRAEGRQSYAVLLFAPSTKPFDLFEPERKGRVKLYVRRVFITADADLLPPYLRFLR
GVIDSEDLPLNLSREMLQNNPQLAQIRKAVTGKVIGELDSLADKQPEQFAKIWDAFGPVIKEGLYEDYERREKLLSLARF
TTTAGEKRSLAQYVEAMKENQTEIYYLVGDSLDRLKANPKLESAAARGIEVLLLTDAVDAFWTSGGLDFGGKPLKSLSQG
EVNFDLIPKLDADKAEDKPDEAKADEATVIAVIKDALGDRVSDVKASQRLTASASCLVAGGFGPDRELEKMLARANKGAA
TKPVLEINLGHPLVAALADTKADKADATDLSFLLLEQAQILDGELPEDPAAFAGRLNRLVLRGVVAHG
>Mature_627_residues
TTIDTASETKPFQAEVAELLNLMVHSVYSETDIFLRELISNASDALDKLRYESIANPALMADGGEPKIRIVPKKAPDTLT
VIDNGIGMDRQELIDNLGTIAKSGTKSFLTKLTEAKDGAGLIGQFGVGFYAAFMVADSITVTSRRAGSAEAWTWSSSGGA
GFEIAPASEEAAARIERGTEIVLHLKPDAAKYLEAYQIERIVSEYSDNIQFPIELVPEDGEPRQINSASALWQRSKSELT
EEDYKQAYKQVAGAFDEPAMTLHYRAEGRQSYAVLLFAPSTKPFDLFEPERKGRVKLYVRRVFITADADLLPPYLRFLRG
VIDSEDLPLNLSREMLQNNPQLAQIRKAVTGKVIGELDSLADKQPEQFAKIWDAFGPVIKEGLYEDYERREKLLSLARFT
TTAGEKRSLAQYVEAMKENQTEIYYLVGDSLDRLKANPKLESAAARGIEVLLLTDAVDAFWTSGGLDFGGKPLKSLSQGE
VNFDLIPKLDADKAEDKPDEAKADEATVIAVIKDALGDRVSDVKASQRLTASASCLVAGGFGPDRELEKMLARANKGAAT
KPVLEINLGHPLVAALADTKADKADATDLSFLLLEQAQILDGELPEDPAAFAGRLNRLVLRGVVAHG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=649, Percent_Identity=33.7442218798151, Blast_Score=341, Evalue=1e-93,
Organism=Homo sapiens, GI4507677, Length=416, Percent_Identity=34.8557692307692, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=34.5410628019324, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=34.5410628019324, Blast_Score=229, Evalue=7e-60,
Organism=Homo sapiens, GI20149594, Length=414, Percent_Identity=34.7826086956522, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=42.8571428571429, Blast_Score=477, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=37.295690936107, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17542208, Length=670, Percent_Identity=36.1194029850746, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI115535205, Length=634, Percent_Identity=35.6466876971609, Blast_Score=335, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI115535167, Length=422, Percent_Identity=39.0995260663507, Blast_Score=273, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=37.3900293255132, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6325016, Length=418, Percent_Identity=36.8421052631579, Blast_Score=246, Evalue=6e-66,
Organism=Drosophila melanogaster, GI21357739, Length=676, Percent_Identity=33.8757396449704, Blast_Score=351, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24586016, Length=634, Percent_Identity=34.2271293375394, Blast_Score=318, Evalue=8e-87,
Organism=Drosophila melanogaster, GI17647529, Length=417, Percent_Identity=35.0119904076739, Blast_Score=246, Evalue=3e-65,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_RHOP2 (Q2IQY5)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_488286.1
- HSSP:   P07900
- ProteinModelPortal:   Q2IQY5
- STRING:   Q2IQY5
- GeneID:   3912510
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_4692
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   RPAL316058:RPB_4692-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 68606; Mature: 68475

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIDTASETKPFQAEVAELLNLMVHSVYSETDIFLRELISNASDALDKLRYESIANPAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MADGGEPKIRIVPKKAPDTLTVIDNGIGMDRQELIDNLGTIAKSGTKSFLTKLTEAKDGA
EECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GLIGQFGVGFYAAFMVADSITVTSRRAGSAEAWTWSSSGGAGFEIAPASEEAAARIERGT
CCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEECCCCCCCEEECCCCHHHHHHHHCCC
EIVLHLKPDAAKYLEAYQIERIVSEYSDNIQFPIELVPEDGEPRQINSASALWQRSKSEL
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHC
TEEDYKQAYKQVAGAFDEPAMTLHYRAEGRQSYAVLLFAPSTKPFDLFEPERKGRVKLYV
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
RRVFITADADLLPPYLRFLRGVIDSEDLPLNLSREMLQNNPQLAQIRKAVTGKVIGELDS
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LADKQPEQFAKIWDAFGPVIKEGLYEDYERREKLLSLARFTTTAGEKRSLAQYVEAMKEN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
QTEIYYLVGDSLDRLKANPKLESAAARGIEVLLLTDAVDAFWTSGGLDFGGKPLKSLSQG
CCEEEEEECCCHHHHCCCCCHHHHHHCCEEEEEEEHHHHHHHCCCCCCCCCCCHHHHCCC
EVNFDLIPKLDADKAEDKPDEAKADEATVIAVIKDALGDRVSDVKASQRLTASASCLVAG
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEC
GFGPDRELEKMLARANKGAATKPVLEINLGHPLVAALADTKADKADATDLSFLLLEQAQI
CCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LDGELPEDPAAFAGRLNRLVLRGVVAHG
HCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTIDTASETKPFQAEVAELLNLMVHSVYSETDIFLRELISNASDALDKLRYESIANPAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MADGGEPKIRIVPKKAPDTLTVIDNGIGMDRQELIDNLGTIAKSGTKSFLTKLTEAKDGA
EECCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GLIGQFGVGFYAAFMVADSITVTSRRAGSAEAWTWSSSGGAGFEIAPASEEAAARIERGT
CCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEECCCCCCCEEECCCCHHHHHHHHCCC
EIVLHLKPDAAKYLEAYQIERIVSEYSDNIQFPIELVPEDGEPRQINSASALWQRSKSEL
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHC
TEEDYKQAYKQVAGAFDEPAMTLHYRAEGRQSYAVLLFAPSTKPFDLFEPERKGRVKLYV
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
RRVFITADADLLPPYLRFLRGVIDSEDLPLNLSREMLQNNPQLAQIRKAVTGKVIGELDS
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LADKQPEQFAKIWDAFGPVIKEGLYEDYERREKLLSLARFTTTAGEKRSLAQYVEAMKEN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
QTEIYYLVGDSLDRLKANPKLESAAARGIEVLLLTDAVDAFWTSGGLDFGGKPLKSLSQG
CCEEEEEECCCHHHHCCCCCHHHHHHCCEEEEEEEHHHHHHHCCCCCCCCCCCHHHHCCC
EVNFDLIPKLDADKAEDKPDEAKADEATVIAVIKDALGDRVSDVKASQRLTASASCLVAG
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEC
GFGPDRELEKMLARANKGAATKPVLEINLGHPLVAALADTKADKADATDLSFLLLEQAQI
CCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LDGELPEDPAAFAGRLNRLVLRGVVAHG
HCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA