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The map label for this gene is dapA [H]

Identifier: 86751066

GI number: 86751066

Start: 4518274

End: 4519149

Strand: Reverse

Name: dapA [H]

Synonym: RPB_3958

Alternate gene names: 86751066

Gene position: 4519149-4518274 (Counterclockwise)

Preceding gene: 86751070

Following gene: 86751065

Centisome position: 84.76

GC content: 66.89

Gene sequence:

>876_bases
ATGACTGAATTTCGAGGCGTTTTTCCCTATCTGGTGTCTCCCCTCGAGTCTGACGGCCGGGTCCGCGGCGAGGTGCTCGG
CCGGCTCTGCGACGATCTGGTCAAGGCCGGGGTGCACGGGCTGACGCCGCTCGGCTCGACCGGCGAGTTTGCCTATCTCG
GCGCGGCGCAGCGCACGGCCGTGGTGCAGGCGACGATCGAGGCCGCGGCTGGCCGCGTGCCGGTGGTCGCCGGCGTGGCG
TCGACCTCGACCGCGGATGCGGTGGCGCAGGCCAGGGCCTATCAGAAACACGGTGCCGACGGCATCCTGGCGATTCTGGA
GGCGTATTTTCCGCTGAAGGACGCGCAGATCGAGAGTTATTTTCGCGCGATCGCCGACGCCGTCGATATCCCGGTGGTGA
TCTACACCAATCCGCAATTCCAGCGCTCGGACCTGACGCTCGACGTGATCGCGCGGCTCGCTGAACATCCGCGCATCCGC
TACATCAAGGACGCCTCGACCAACACCGGCCGGCTGCTGTCGATCATGAATCGTTGCGGTGATTCGTTGCGGGTGTTCTC
GGCCTCGGCGCATATTCCGGCCGCGGTGATGCTGATCGGCGGCGTCGGCTGGATGGCCGGCCCGGCCTGCATCGCGCCGC
GCCAGAGCGTGCGTTTGTACGAGTTGTGCAAGGCGCAGCGCTGGGACGAAGCGCTGACGCTTCAACGCAAACTCTGGCGC
GTCAACGAAGCCTTCGCCAAGTTCAACCTCGCCGCCTGCATCAAGGCCGGCCTCGCGCTGCAGGGCTACGACGTCGGCGA
CCCGGTGCCGCCGCAAGCCGCGCTGACGGCCGAAGAGCGCAAGGCGGTCGAGAAGGTGCTGGCGGAGATCGCGTAA

Upstream 100 bases:

>100_bases
TTGGCTTAGCAGAGTTTGGCGCTTGCGGCGCGCGCCGGATTGATGTCGATAGGCCGCGGCCGGTTCCGGCTTCCGCCAGA
GACAGCATGTGGTTCTGCAA

Downstream 100 bases:

>100_bases
GACTCTCGATCGTCATTCCGGGGCGCGCTGCGAAGCTGCGCGAACCCGGAATCTCGAGATGTTCTGCGTTGAACGCGGGT
GACCTGAACGTCGAGATTCC

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTEFRGVFPYLVSPLESDGRVRGEVLGRLCDDLVKAGVHGLTPLGSTGEFAYLGAAQRTAVVQATIEAAAGRVPVVAGVA
STSTADAVAQARAYQKHGADGILAILEAYFPLKDAQIESYFRAIADAVDIPVVIYTNPQFQRSDLTLDVIARLAEHPRIR
YIKDASTNTGRLLSIMNRCGDSLRVFSASAHIPAAVMLIGGVGWMAGPACIAPRQSVRLYELCKAQRWDEALTLQRKLWR
VNEAFAKFNLAACIKAGLALQGYDVGDPVPPQAALTAEERKAVEKVLAEIA

Sequences:

>Translated_291_residues
MTEFRGVFPYLVSPLESDGRVRGEVLGRLCDDLVKAGVHGLTPLGSTGEFAYLGAAQRTAVVQATIEAAAGRVPVVAGVA
STSTADAVAQARAYQKHGADGILAILEAYFPLKDAQIESYFRAIADAVDIPVVIYTNPQFQRSDLTLDVIARLAEHPRIR
YIKDASTNTGRLLSIMNRCGDSLRVFSASAHIPAAVMLIGGVGWMAGPACIAPRQSVRLYELCKAQRWDEALTLQRKLWR
VNEAFAKFNLAACIKAGLALQGYDVGDPVPPQAALTAEERKAVEKVLAEIA
>Mature_290_residues
TEFRGVFPYLVSPLESDGRVRGEVLGRLCDDLVKAGVHGLTPLGSTGEFAYLGAAQRTAVVQATIEAAAGRVPVVAGVAS
TSTADAVAQARAYQKHGADGILAILEAYFPLKDAQIESYFRAIADAVDIPVVIYTNPQFQRSDLTLDVIARLAEHPRIRY
IKDASTNTGRLLSIMNRCGDSLRVFSASAHIPAAVMLIGGVGWMAGPACIAPRQSVRLYELCKAQRWDEALTLQRKLWRV
NEAFAKFNLAACIKAGLALQGYDVGDPVPPQAALTAEERKAVEKVLAEIA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=284, Percent_Identity=26.7605633802817, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI87082415, Length=292, Percent_Identity=32.5342465753425, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786463, Length=297, Percent_Identity=30.3030303030303, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788823, Length=260, Percent_Identity=28.4615384615385, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789620, Length=203, Percent_Identity=29.064039408867, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31250; Mature: 31119

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFRGVFPYLVSPLESDGRVRGEVLGRLCDDLVKAGVHGLTPLGSTGEFAYLGAAQRTA
CCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
VVQATIEAAAGRVPVVAGVASTSTADAVAQARAYQKHGADGILAILEAYFPLKDAQIESY
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
FRAIADAVDIPVVIYTNPQFQRSDLTLDVIARLAEHPRIRYIKDASTNTGRLLSIMNRCG
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCC
DSLRVFSASAHIPAAVMLIGGVGWMAGPACIAPRQSVRLYELCKAQRWDEALTLQRKLWR
CCEEEEECCCCCCHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNEAFAKFNLAACIKAGLALQGYDVGDPVPPQAALTAEERKAVEKVLAEIA
HHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEFRGVFPYLVSPLESDGRVRGEVLGRLCDDLVKAGVHGLTPLGSTGEFAYLGAAQRTA
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
VVQATIEAAAGRVPVVAGVASTSTADAVAQARAYQKHGADGILAILEAYFPLKDAQIESY
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
FRAIADAVDIPVVIYTNPQFQRSDLTLDVIARLAEHPRIRYIKDASTNTGRLLSIMNRCG
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCC
DSLRVFSASAHIPAAVMLIGGVGWMAGPACIAPRQSVRLYELCKAQRWDEALTLQRKLWR
CCEEEEECCCCCCHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNEAFAKFNLAACIKAGLALQGYDVGDPVPPQAALTAEERKAVEKVLAEIA
HHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA