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The map label for this gene is cutL [H]

Identifier: 86751065

GI number: 86751065

Start: 4515405

End: 4517735

Strand: Reverse

Name: cutL [H]

Synonym: RPB_3957

Alternate gene names: 86751065

Gene position: 4517735-4515405 (Counterclockwise)

Preceding gene: 86751066

Following gene: 86751064

Centisome position: 84.73

GC content: 68.51

Gene sequence:

>2331_bases
ATGAACATTCTTCCCGGCTCCATGCGGTTCGGCGCGGGGCAGCCCGTCAAGCGTCTCGAGGATCAGCGGCTCGTCACCGG
ACACGGGCACTATCTCGACGACAAGCCCGCCGACGGCGCGTTGTGGCTGGTGGTGCTGCGCTCACCACACGCGCACGCCA
AGATCGTCTCGATCGATGCCGAGGCGGCGCGCGCGATGCCGGGAGTCGAAAGCGTTCTGACCGGCGCGGACCTCGTCGCC
GACGAGATCGGCACGATCCCGACCCTGCCGATCTTCAAGCGGCCGGACGGTTCGCCGATGCTGCTGCCGCCGCGCCGGCT
CTTGGCGCACGAGATCGTCCGCTTCGTCGGCGAGCCGGTCGCCGCGGTGATCGCGGCGTCGCAGGCCGCGGCGCAGGCTG
CGGCCGAGGCGGTCGTCGTCGAGTATGAAGAATTGCCGGCGGTGACCGATCCGGTCGCGGCGATCCAGCCCGGCGCGCCG
GTGGTGGTCGAGACCGCGCCCGACAACATCGTCGCGGCGATGAGCTATGGCGATGCCGCCAAGGTCGATGAGGCTTTCGC
CAGCGCCGCGCACACCGTGTCGCTCGACATCGTCAGCCAGCGCCTGATCCCCTCGGCGATGGAGCCGCGCGCCACTATCG
CGGAAATCGAGAAGAAGACCGGCCGGCTGATCCTGCACGTGCAGTCGCAGACGCCGGCGCAGACCCGCGACGCGCTCGCC
GACGCGATCCTGAAGCGGCCGAAGGAGTCGATCCAGGTGCTGGTCGGCGACATCGGCGGCGGTTTCGGCCAGAAGACCGG
CGTCTATCCCGAGGACGCGCTGGTGGCCTATGCGGCGGTGAAGCTCAACAAGAAGATCCGCTGGCGCGGGGACCGCACCG
ACGAATTCGTCGGTGGCACCCATGGCCGCGACCTGACCTCGACCGCGTCGATCGCGCTCGACGCCAAGGGCCGCGTGCTG
GCCTATCGGGTGTCGTCGATCGGCGGCACCGGCGCGTATCTCGCCGGCGCCGGCGTGATCATTCCGCTGGTGCTCGGCCC
GTTCGTGCAGACCGGCGTCTATGATCTGCCGCTGGTGCATTTCGACATCAAGGCGGTGATGACCCACACCGCGCCCGTCG
GCGCCTATCGCGGCGCAGGCCGCCCGGAAGCCGTGTACATCATCGAGCGCCTGATGGACGCCGCGGCGCGCCAGCTGAAC
ATGGACCCGCGCGCGATCCGCAAGGTCAACTACATCAAGCCGACGCAACTGCCCTACACCAACGCGGTCGGGCAGGTGTA
CGATTCGGGCGCCTTCGCGCATCTGATGCAGCGCGCGACCGAGCTGTCCGACTGGGACGGCTTCAAGGCGCGCAAGAAGG
AAGCGCAGAAGAAGGGCCTGCTCTACGGCCGCGGCGTCACCAGCTACATCGAATGGACCGGCGGCCGCGCCCACACCGAG
AAGGTCAGCCTGCACGCCACCGCGGAAGGCCGCATCGTGCTGCATTCCGGCACGCAGGCGATGGGGCAGGGGCTGGAGAC
CACCTACTCGCAGATGATCGCGCAGGCGCTCGACATCCCGATCGAGAGCATCGACGTCGTGCAGGGCAACACCGATCTGG
CGCAGGGCTTCGGCAGCGTCGGCTCGCGCTCGCTGTTCGTCGGCGGCACCGCGGTCGCGGTGTCGACCGTCGATATGATC
GCCAAAGCGCGCGAGAAGGCCGCGAACATTCTCGAAGCCTCGATCGAGGACATCGAGTATTCCGGCGGCATGCTGACGAT
CGCCGGCACCGATCGCAAGATCAGCCTGTTCGAAATCGCCGCCAAGGAAAAAGGTACCAAGCTCAGCGTCGATTCGACCG
GCGAAGTCGACGGTCCGAGCTGGCCGAACGGCGCGCATATCTGCGAGGTCGAGGTCGATCCCGAAACCGGCGTCAGCCGT
GTGGTGCGCTACACCACGGTCGACGACGTCGGCAATGCGGTCAATCCGATGCTGGTCGCGGGGCAGATCCATGGCGGCGT
CGCGCAGGGCGTCGGCCAGGCGCTGTACGAAGGCGCGGCCTATAACGACGACGGCCAGCTGCTGACCGCGAGCTATCAGG
ACTACTGCATCCCGCGCGCCGACAATCTGCCGCCGATCAACGTCACGCTCGATCCGTCGGCGCCGTGCCGGACCAATCCG
CTCGGCGCCAAGGGCTGCGGCGAATCCGGCGCGATCGGTGGGCCGCCCTGCGTCGTCCACGGCGTGCTCGACGCGCTGGC
GCCGCTCGGCGTCACCACGCTGAACACGCCGCTGACCCCGGAAAAGGTGTGGCGGGCGATCCAGGACGCCAAGGCCGCGC
AGGCGGCCTGA

Upstream 100 bases:

>100_bases
GGAGAGGTTCGGCTTCGCTTCGGGGAGGGGCTTGCCCCTCTTGGCTTACCGCTGCTTTCTCCGCTAAAACCGTTCCAAGC
AAGCAACACAAGGAAGCGGC

Downstream 100 bases:

>100_bases
CCCGGAGCAGCATCACCGCTCGTCATGCCCGCGCTTGTCGCGGGCATCCACGTCTTCGAGGCTCAACCTCAGCAAAGACG
TGGATGGCCGGGACGAGCCC

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MNILPGSMRFGAGQPVKRLEDQRLVTGHGHYLDDKPADGALWLVVLRSPHAHAKIVSIDAEAARAMPGVESVLTGADLVA
DEIGTIPTLPIFKRPDGSPMLLPPRRLLAHEIVRFVGEPVAAVIAASQAAAQAAAEAVVVEYEELPAVTDPVAAIQPGAP
VVVETAPDNIVAAMSYGDAAKVDEAFASAAHTVSLDIVSQRLIPSAMEPRATIAEIEKKTGRLILHVQSQTPAQTRDALA
DAILKRPKESIQVLVGDIGGGFGQKTGVYPEDALVAYAAVKLNKKIRWRGDRTDEFVGGTHGRDLTSTASIALDAKGRVL
AYRVSSIGGTGAYLAGAGVIIPLVLGPFVQTGVYDLPLVHFDIKAVMTHTAPVGAYRGAGRPEAVYIIERLMDAAARQLN
MDPRAIRKVNYIKPTQLPYTNAVGQVYDSGAFAHLMQRATELSDWDGFKARKKEAQKKGLLYGRGVTSYIEWTGGRAHTE
KVSLHATAEGRIVLHSGTQAMGQGLETTYSQMIAQALDIPIESIDVVQGNTDLAQGFGSVGSRSLFVGGTAVAVSTVDMI
AKAREKAANILEASIEDIEYSGGMLTIAGTDRKISLFEIAAKEKGTKLSVDSTGEVDGPSWPNGAHICEVEVDPETGVSR
VVRYTTVDDVGNAVNPMLVAGQIHGGVAQGVGQALYEGAAYNDDGQLLTASYQDYCIPRADNLPPINVTLDPSAPCRTNP
LGAKGCGESGAIGGPPCVVHGVLDALAPLGVTTLNTPLTPEKVWRAIQDAKAAQAA

Sequences:

>Translated_776_residues
MNILPGSMRFGAGQPVKRLEDQRLVTGHGHYLDDKPADGALWLVVLRSPHAHAKIVSIDAEAARAMPGVESVLTGADLVA
DEIGTIPTLPIFKRPDGSPMLLPPRRLLAHEIVRFVGEPVAAVIAASQAAAQAAAEAVVVEYEELPAVTDPVAAIQPGAP
VVVETAPDNIVAAMSYGDAAKVDEAFASAAHTVSLDIVSQRLIPSAMEPRATIAEIEKKTGRLILHVQSQTPAQTRDALA
DAILKRPKESIQVLVGDIGGGFGQKTGVYPEDALVAYAAVKLNKKIRWRGDRTDEFVGGTHGRDLTSTASIALDAKGRVL
AYRVSSIGGTGAYLAGAGVIIPLVLGPFVQTGVYDLPLVHFDIKAVMTHTAPVGAYRGAGRPEAVYIIERLMDAAARQLN
MDPRAIRKVNYIKPTQLPYTNAVGQVYDSGAFAHLMQRATELSDWDGFKARKKEAQKKGLLYGRGVTSYIEWTGGRAHTE
KVSLHATAEGRIVLHSGTQAMGQGLETTYSQMIAQALDIPIESIDVVQGNTDLAQGFGSVGSRSLFVGGTAVAVSTVDMI
AKAREKAANILEASIEDIEYSGGMLTIAGTDRKISLFEIAAKEKGTKLSVDSTGEVDGPSWPNGAHICEVEVDPETGVSR
VVRYTTVDDVGNAVNPMLVAGQIHGGVAQGVGQALYEGAAYNDDGQLLTASYQDYCIPRADNLPPINVTLDPSAPCRTNP
LGAKGCGESGAIGGPPCVVHGVLDALAPLGVTTLNTPLTPEKVWRAIQDAKAAQAA
>Mature_776_residues
MNILPGSMRFGAGQPVKRLEDQRLVTGHGHYLDDKPADGALWLVVLRSPHAHAKIVSIDAEAARAMPGVESVLTGADLVA
DEIGTIPTLPIFKRPDGSPMLLPPRRLLAHEIVRFVGEPVAAVIAASQAAAQAAAEAVVVEYEELPAVTDPVAAIQPGAP
VVVETAPDNIVAAMSYGDAAKVDEAFASAAHTVSLDIVSQRLIPSAMEPRATIAEIEKKTGRLILHVQSQTPAQTRDALA
DAILKRPKESIQVLVGDIGGGFGQKTGVYPEDALVAYAAVKLNKKIRWRGDRTDEFVGGTHGRDLTSTASIALDAKGRVL
AYRVSSIGGTGAYLAGAGVIIPLVLGPFVQTGVYDLPLVHFDIKAVMTHTAPVGAYRGAGRPEAVYIIERLMDAAARQLN
MDPRAIRKVNYIKPTQLPYTNAVGQVYDSGAFAHLMQRATELSDWDGFKARKKEAQKKGLLYGRGVTSYIEWTGGRAHTE
KVSLHATAEGRIVLHSGTQAMGQGLETTYSQMIAQALDIPIESIDVVQGNTDLAQGFGSVGSRSLFVGGTAVAVSTVDMI
AKAREKAANILEASIEDIEYSGGMLTIAGTDRKISLFEIAAKEKGTKLSVDSTGEVDGPSWPNGAHICEVEVDPETGVSR
VVRYTTVDDVGNAVNPMLVAGQIHGGVAQGVGQALYEGAAYNDDGQLLTASYQDYCIPRADNLPPINVTLDPSAPCRTNP
LGAKGCGESGAIGGPPCVVHGVLDALAPLGVTTLNTPLTPEKVWRAIQDAKAAQAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=788, Percent_Identity=27.0304568527919, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI91823271, Length=792, Percent_Identity=25.6313131313131, Blast_Score=167, Evalue=4e-41,
Organism=Escherichia coli, GI1789246, Length=810, Percent_Identity=26.5432098765432, Blast_Score=221, Evalue=2e-58,
Organism=Escherichia coli, GI1789230, Length=774, Percent_Identity=26.2273901808786, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1786478, Length=779, Percent_Identity=25.0320924261874, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=715, Percent_Identity=26.4335664335664, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17540638, Length=801, Percent_Identity=24.2197253433208, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=493, Percent_Identity=26.7748478701826, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737937, Length=757, Percent_Identity=24.7027741083223, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24647193, Length=773, Percent_Identity=25.3557567917206, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647199, Length=793, Percent_Identity=24.0857503152585, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81689; Mature: 81689

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILPGSMRFGAGQPVKRLEDQRLVTGHGHYLDDKPADGALWLVVLRSPHAHAKIVSIDA
CCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECH
EAARAMPGVESVLTGADLVADEIGTIPTLPIFKRPDGSPMLLPPRRLLAHEIVRFVGEPV
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEECCHHHHHHHHHHHHHCCCH
AAVIAASQAAAQAAAEAVVVEYEELPAVTDPVAAIQPGAPVVVETAPDNIVAAMSYGDAA
HHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCHHHCCCCCCEEEEECCCCEEEEECCCCHH
KVDEAFASAAHTVSLDIVSQRLIPSAMEPRATIAEIEKKTGRLILHVQSQTPAQTRDALA
HHHHHHHHHHHEEEHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
DAILKRPKESIQVLVGDIGGGFGQKTGVYPEDALVAYAAVKLNKKIRWRGDRTDEFVGGT
HHHHHCCCHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCC
HGRDLTSTASIALDAKGRVLAYRVSSIGGTGAYLAGAGVIIPLVLGPFVQTGVYDLPLVH
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEE
FDIKAVMTHTAPVGAYRGAGRPEAVYIIERLMDAAARQLNMDPRAIRKVNYIKPTQLPYT
EEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCC
NAVGQVYDSGAFAHLMQRATELSDWDGFKARKKEAQKKGLLYGRGVTSYIEWTGGRAHTE
HHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCHHEEEECCCCCCCE
KVSLHATAEGRIVLHSGTQAMGQGLETTYSQMIAQALDIPIESIDVVQGNTDLAQGFGSV
EEEEEEECCCEEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCC
GSRSLFVGGTAVAVSTVDMIAKAREKAANILEASIEDIEYSGGMLTIAGTDRKISLFEIA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEH
AKEKGTKLSVDSTGEVDGPSWPNGAHICEVEVDPETGVSRVVRYTTVDDVGNAVNPMLVA
HCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEEEEEHHHCCCCCCCEEEE
GQIHGGVAQGVGQALYEGAAYNDDGQLLTASYQDYCIPRADNLPPINVTLDPSAPCRTNP
EECCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCC
LGAKGCGESGAIGGPPCVVHGVLDALAPLGVTTLNTPLTPEKVWRAIQDAKAAQAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILPGSMRFGAGQPVKRLEDQRLVTGHGHYLDDKPADGALWLVVLRSPHAHAKIVSIDA
CCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECH
EAARAMPGVESVLTGADLVADEIGTIPTLPIFKRPDGSPMLLPPRRLLAHEIVRFVGEPV
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEECCHHHHHHHHHHHHHCCCH
AAVIAASQAAAQAAAEAVVVEYEELPAVTDPVAAIQPGAPVVVETAPDNIVAAMSYGDAA
HHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCHHHCCCCCCEEEEECCCCEEEEECCCCHH
KVDEAFASAAHTVSLDIVSQRLIPSAMEPRATIAEIEKKTGRLILHVQSQTPAQTRDALA
HHHHHHHHHHHEEEHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
DAILKRPKESIQVLVGDIGGGFGQKTGVYPEDALVAYAAVKLNKKIRWRGDRTDEFVGGT
HHHHHCCCHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCC
HGRDLTSTASIALDAKGRVLAYRVSSIGGTGAYLAGAGVIIPLVLGPFVQTGVYDLPLVH
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCEEE
FDIKAVMTHTAPVGAYRGAGRPEAVYIIERLMDAAARQLNMDPRAIRKVNYIKPTQLPYT
EEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCC
NAVGQVYDSGAFAHLMQRATELSDWDGFKARKKEAQKKGLLYGRGVTSYIEWTGGRAHTE
HHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCHHEEEECCCCCCCE
KVSLHATAEGRIVLHSGTQAMGQGLETTYSQMIAQALDIPIESIDVVQGNTDLAQGFGSV
EEEEEEECCCEEEEECCCHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCC
GSRSLFVGGTAVAVSTVDMIAKAREKAANILEASIEDIEYSGGMLTIAGTDRKISLFEIA
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEH
AKEKGTKLSVDSTGEVDGPSWPNGAHICEVEVDPETGVSRVVRYTTVDDVGNAVNPMLVA
HCCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEEEEEHHHCCCCCCCEEEE
GQIHGGVAQGVGQALYEGAAYNDDGQLLTASYQDYCIPRADNLPPINVTLDPSAPCRTNP
EECCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCC
LGAKGCGESGAIGGPPCVVHGVLDALAPLGVTTLNTPLTPEKVWRAIQDAKAAQAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]