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The map label for this gene is zraS [C]

Identifier: 86750880

GI number: 86750880

Start: 4305452

End: 4308076

Strand: Reverse

Name: zraS [C]

Synonym: RPB_3771

Alternate gene names: 86750880

Gene position: 4308076-4305452 (Counterclockwise)

Preceding gene: 86750881

Following gene: 86750878

Centisome position: 80.8

GC content: 68.3

Gene sequence:

>2625_bases
ATGTACTTGCGCGGGCGGCTCCGATTCAGGCAGGTGGAGCCGGGCCGCCGCAGCGCCGGCGGGCAAGGGAACGGTTCGGT
GACCATGACCATCAACGACCATCAGGCTCCGCCGCCCGCCGCGGAGCCGGCGCGCCGCGGTGGCAGCATCGCTCTGGTGT
TGCTGGTGGCAGGCGCCATCGTCGCCGCCGCTGTGGCGTTCATGACGCTCGGCCGCGCCGAGGCGCAGCCCTATATTCTC
GGCCTGCTGGCGCTGTTGGCGATGGTCGGGCTGTTCATGCTGTTCGCCTTCGCCGCCGGCATCGTCGGCTTCGCCGACCG
GGCTGCCGACGATCCGGTGCTGCGGGCAATCGCGGAAGGCGCCTTCGACGGTATCGCCGTCACGGACGCGCGCGGCCATG
TGGTCTATGCCAACCCGGTCTATCTGGCGCTGACTGGTGCGGCGACGATGCAGGACGTCCGTCCGGTCGAGCGGGTGTTC
ATCGGCAATCCCGATGTGTCGGAAGCCGTGTTCCGGCTGCTGAAGGCGGCGCGCGAGGGCAAGCGGCTGCAGGAAGAGGT
TCGCGTCGCCGGCGCCGACGGCGCGCAGGGCCGCTGGATGCGGATGCGGGTGCGCCCACTCGGGCCCGGCAAGCGCGAGG
CGAAGCAGACGGTGTGGTCGCTGGCCGACATCACCCGCGACCGCGAACACCAGGAAGACGTGTTCCAGGAGCTGCAGCAC
GCCATCGAATATCTCGACCACGCGCCTTGCGGGTTCTTTTCGGTCGATTCCGCGGGCAACCTCGTTTACGTCAACGCGAC
GCTGGCGAACTGGCTCGACCACGACCTCGCGGAGATCGGCTCGGGCGGCCTGAAGCTCGGCGACATCGTTTCCGGCGACG
GCGCGGCGCTCTTGACCTCGATCGTGCCCGAGCCGGGCGAGGTCAAGACCGAGGTGTTCGACATCGATCTGAAGATGCGT
AGCGGCAAGACCATGCCGGTGCGGCTGTATCACAAGCTCGCCTTCGGCGCCGACGGCGCGCCGGGCGCGTCGCGCACGCT
GGTGATCAGCCGCGCCCGCGATGAGCGGCTCGATCCGCAGCGCGCCGCCGAAATCCGCTTCATGCGGTTCTTCGACCACA
CCCCGATGGCGATCGCCACGGTGGACAAAGCCGGTGCGGTGGTGCGCGCCAATGCCCGCTTCGCCAAGCTGGCGCAGAGT
CTCGATCCGTCGGGTGGCGCGGCGAGATCGATCCTCGCCGCGGTCAGCACCCGCGATCGCGCCACGCTCGGCGCGGCGAT
CGATCAGGCCGCGCAGGGCCAAGCCGACATCGCGCCCGTCGAGGTGATGCTCGACGGTGCCAAGGAGCGCTGGGGCCAGT
TCTTCGTCACCGCGGTCGCCGACGACGGCGACGCCGAGGCCGCGATCGTCTATCTGCTCGAGACCACCGAGCGCCGCGCG
CTGGAGAACCAGGTCAACCAGGCGCAGAAGATGGACACGATCGGCCAGCTCGCCGGCGGCATCGCGCACGATTTCAACAA
CGTGCTCTCGGCCATCATGATGGCCAACGACTTCCTGCTGAACGCGCACAAGCCGACCGACCCGTCGTTCCAGGACATCA
TGCAGATCAAGCAGAACGCCACCCGCGCCGCCACGCTGGTGCGGCAGCTGCTGGCGTTCTCGCGCAAGCAGACGCTGCGG
CCGCAGGTGCTCGATCTCGGCGAGGCGCTGACCGACATCGACCGGCTGCTGAAGCGGCTGATCGGCGAGAAGGTCTCACT
CGAGATGCAGCACGGCCGCGATCTGTGGCGGGTCAAGGCCGACGTCTCGCAATTCGAGCAGGTGATCGTCAATCTCGCGG
TCAATGCCCGCGACGCGATGCCCGACGGCGGCAAGCTGGCGATCCGCACCTCCAACGTCCCGGCCGCCGAGGCGGCGCAG
CTCGCCCACAAGGGCATGCCGGCGGCGGACTACGTGCGGATCGACGTCAGCGACACCGGCACCGGCATTCCGGCCGACAT
CGTCGACAAGATCTTCGAGCCGTTTTTCTCGACCAAGGAAGTCGGCAAGGGCACCGGCCTCGGGCTGTCGACCGTGTACG
GCATCATCAAGCAGACCGGCGGCTTCGTTTACGTCGACTCCGAGCCCGGCAAAGGCACCACCTTCCACATCTTCCTGCCG
CGCCACGATGCGCTGCCCGAGGCGCAGCCGGACGCGCCGGCGCCGATCAGCAGCGCGACGACCGCCGCCGCGAAGCCCCG
CGCCGACATGACCGGGCAGGGCACCATCCTGCTGGTCGAGGACGAGGAGGGGCTGCGCTCGCTCAACGCCCGCGGCCTGC
GCTCGCGCGGCTACAACGTGATCGAAGCCGGCAACGGCATCGAGGCGCTGGAAGAGTTCGACGCTCATGGCGGTGCGGTC
GATCTCGTGGTCTCCGACGTGGTGATGCCGGAGATGGACGGGCCGACTTTGCTGAAAGCGATGCGCGCGCGCAATTCCGA
GCTCAAGATCATCTTCGTCTCCGGCTACGCCGAAGACGCGTTCGAGAAGAGCCTGCCGGAGAACGAACAATTCGCGTTCC
TGGCGAAGCCCTTCGCGCTCAGCGCGCTGGTCGCGAAGGTGAAGGAGACGATGGGGGCGAACTAA

Upstream 100 bases:

>100_bases
TGGCGATGCCCGGGCCAGCCGATGTGGGTGAGCGGATTTTCCGGAGTTGCGGCTCCGATCGCGCCCTTCCGGCCGGTCGG
GGGAGGCGCGGGGACAGAGG

Downstream 100 bases:

>100_bases
TCGCTCCATTGACCTATGCCTGCGCGCAGGCGGGGCGCGGTCCAGTCGAGGAAACTCCGCACCTTCGGCGGCAAGGGAAC
CGCCGGCGCATGGATGAGGT

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MYLRGRLRFRQVEPGRRSAGGQGNGSVTMTINDHQAPPPAAEPARRGGSIALVLLVAGAIVAAAVAFMTLGRAEAQPYIL
GLLALLAMVGLFMLFAFAAGIVGFADRAADDPVLRAIAEGAFDGIAVTDARGHVVYANPVYLALTGAATMQDVRPVERVF
IGNPDVSEAVFRLLKAAREGKRLQEEVRVAGADGAQGRWMRMRVRPLGPGKREAKQTVWSLADITRDREHQEDVFQELQH
AIEYLDHAPCGFFSVDSAGNLVYVNATLANWLDHDLAEIGSGGLKLGDIVSGDGAALLTSIVPEPGEVKTEVFDIDLKMR
SGKTMPVRLYHKLAFGADGAPGASRTLVISRARDERLDPQRAAEIRFMRFFDHTPMAIATVDKAGAVVRANARFAKLAQS
LDPSGGAARSILAAVSTRDRATLGAAIDQAAQGQADIAPVEVMLDGAKERWGQFFVTAVADDGDAEAAIVYLLETTERRA
LENQVNQAQKMDTIGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRKQTLR
PQVLDLGEALTDIDRLLKRLIGEKVSLEMQHGRDLWRVKADVSQFEQVIVNLAVNARDAMPDGGKLAIRTSNVPAAEAAQ
LAHKGMPAADYVRIDVSDTGTGIPADIVDKIFEPFFSTKEVGKGTGLGLSTVYGIIKQTGGFVYVDSEPGKGTTFHIFLP
RHDALPEAQPDAPAPISSATTAAAKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYNVIEAGNGIEALEEFDAHGGAV
DLVVSDVVMPEMDGPTLLKAMRARNSELKIIFVSGYAEDAFEKSLPENEQFAFLAKPFALSALVAKVKETMGAN

Sequences:

>Translated_874_residues
MYLRGRLRFRQVEPGRRSAGGQGNGSVTMTINDHQAPPPAAEPARRGGSIALVLLVAGAIVAAAVAFMTLGRAEAQPYIL
GLLALLAMVGLFMLFAFAAGIVGFADRAADDPVLRAIAEGAFDGIAVTDARGHVVYANPVYLALTGAATMQDVRPVERVF
IGNPDVSEAVFRLLKAAREGKRLQEEVRVAGADGAQGRWMRMRVRPLGPGKREAKQTVWSLADITRDREHQEDVFQELQH
AIEYLDHAPCGFFSVDSAGNLVYVNATLANWLDHDLAEIGSGGLKLGDIVSGDGAALLTSIVPEPGEVKTEVFDIDLKMR
SGKTMPVRLYHKLAFGADGAPGASRTLVISRARDERLDPQRAAEIRFMRFFDHTPMAIATVDKAGAVVRANARFAKLAQS
LDPSGGAARSILAAVSTRDRATLGAAIDQAAQGQADIAPVEVMLDGAKERWGQFFVTAVADDGDAEAAIVYLLETTERRA
LENQVNQAQKMDTIGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRKQTLR
PQVLDLGEALTDIDRLLKRLIGEKVSLEMQHGRDLWRVKADVSQFEQVIVNLAVNARDAMPDGGKLAIRTSNVPAAEAAQ
LAHKGMPAADYVRIDVSDTGTGIPADIVDKIFEPFFSTKEVGKGTGLGLSTVYGIIKQTGGFVYVDSEPGKGTTFHIFLP
RHDALPEAQPDAPAPISSATTAAAKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYNVIEAGNGIEALEEFDAHGGAV
DLVVSDVVMPEMDGPTLLKAMRARNSELKIIFVSGYAEDAFEKSLPENEQFAFLAKPFALSALVAKVKETMGAN
>Mature_874_residues
MYLRGRLRFRQVEPGRRSAGGQGNGSVTMTINDHQAPPPAAEPARRGGSIALVLLVAGAIVAAAVAFMTLGRAEAQPYIL
GLLALLAMVGLFMLFAFAAGIVGFADRAADDPVLRAIAEGAFDGIAVTDARGHVVYANPVYLALTGAATMQDVRPVERVF
IGNPDVSEAVFRLLKAAREGKRLQEEVRVAGADGAQGRWMRMRVRPLGPGKREAKQTVWSLADITRDREHQEDVFQELQH
AIEYLDHAPCGFFSVDSAGNLVYVNATLANWLDHDLAEIGSGGLKLGDIVSGDGAALLTSIVPEPGEVKTEVFDIDLKMR
SGKTMPVRLYHKLAFGADGAPGASRTLVISRARDERLDPQRAAEIRFMRFFDHTPMAIATVDKAGAVVRANARFAKLAQS
LDPSGGAARSILAAVSTRDRATLGAAIDQAAQGQADIAPVEVMLDGAKERWGQFFVTAVADDGDAEAAIVYLLETTERRA
LENQVNQAQKMDTIGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNATRAATLVRQLLAFSRKQTLR
PQVLDLGEALTDIDRLLKRLIGEKVSLEMQHGRDLWRVKADVSQFEQVIVNLAVNARDAMPDGGKLAIRTSNVPAAEAAQ
LAHKGMPAADYVRIDVSDTGTGIPADIVDKIFEPFFSTKEVGKGTGLGLSTVYGIIKQTGGFVYVDSEPGKGTTFHIFLP
RHDALPEAQPDAPAPISSATTAAAKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYNVIEAGNGIEALEEFDAHGGAV
DLVVSDVVMPEMDGPTLLKAMRARNSELKIIFVSGYAEDAFEKSLPENEQFAFLAKPFALSALVAKVKETMGAN

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=30.327868852459, Blast_Score=113, Evalue=7e-26,
Organism=Escherichia coli, GI1788549, Length=261, Percent_Identity=30.2681992337165, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=32.8125, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788713, Length=277, Percent_Identity=28.8808664259928, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=25.8152173913043, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=79, Percent_Identity=43.0379746835443, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93754; Mature: 93754

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLRGRLRFRQVEPGRRSAGGQGNGSVTMTINDHQAPPPAAEPARRGGSIALVLLVAGAI
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCEEHHHHHHHHH
VAAAVAFMTLGRAEAQPYILGLLALLAMVGLFMLFAFAAGIVGFADRAADDPVLRAIAEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AFDGIAVTDARGHVVYANPVYLALTGAATMQDVRPVERVFIGNPDVSEAVFRLLKAAREG
CCCCEEEECCCCCEEEECCEEEEEECCHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHH
KRLQEEVRVAGADGAQGRWMRMRVRPLGPGKREAKQTVWSLADITRDREHQEDVFQELQH
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AIEYLDHAPCGFFSVDSAGNLVYVNATLANWLDHDLAEIGSGGLKLGDIVSGDGAALLTS
HHHHHHCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCEECCEECCCCHHHHHH
IVPEPGEVKTEVFDIDLKMRSGKTMPVRLYHKLAFGADGAPGASRTLVISRARDERLDPQ
HCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHH
RAAEIRFMRFFDHTPMAIATVDKAGAVVRANARFAKLAQSLDPSGGAARSILAAVSTRDR
HHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCH
ATLGAAIDQAAQGQADIAPVEVMLDGAKERWGQFFVTAVADDGDAEAAIVYLLETTERRA
HHHHHHHHHHHCCCCCCCHHHHEECCHHHHCCEEEEEEEECCCCCCEEEEEEEHHHHHHH
LENQVNQAQKMDTIGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHH
TRAATLVRQLLAFSRKQTLRPQVLDLGEALTDIDRLLKRLIGEKVSLEMQHGRDLWRVKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHH
DVSQFEQVIVNLAVNARDAMPDGGKLAIRTSNVPAAEAAQLAHKGMPAADYVRIDVSDTG
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TGIPADIVDKIFEPFFSTKEVGKGTGLGLSTVYGIIKQTGGFVYVDSEPGKGTTFHIFLP
CCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEC
RHDALPEAQPDAPAPISSATTAAAKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYNV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHCCCEE
IEAGNGIEALEEFDAHGGAVDLVVSDVVMPEMDGPTLLKAMRARNSELKIIFVSGYAEDA
EECCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHH
FEKSLPENEQFAFLAKPFALSALVAKVKETMGAN
HHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLRGRLRFRQVEPGRRSAGGQGNGSVTMTINDHQAPPPAAEPARRGGSIALVLLVAGAI
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHCCCCEEHHHHHHHHH
VAAAVAFMTLGRAEAQPYILGLLALLAMVGLFMLFAFAAGIVGFADRAADDPVLRAIAEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
AFDGIAVTDARGHVVYANPVYLALTGAATMQDVRPVERVFIGNPDVSEAVFRLLKAAREG
CCCCEEEECCCCCEEEECCEEEEEECCHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHH
KRLQEEVRVAGADGAQGRWMRMRVRPLGPGKREAKQTVWSLADITRDREHQEDVFQELQH
HHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AIEYLDHAPCGFFSVDSAGNLVYVNATLANWLDHDLAEIGSGGLKLGDIVSGDGAALLTS
HHHHHHCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCCEECCEECCCCHHHHHH
IVPEPGEVKTEVFDIDLKMRSGKTMPVRLYHKLAFGADGAPGASRTLVISRARDERLDPQ
HCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHH
RAAEIRFMRFFDHTPMAIATVDKAGAVVRANARFAKLAQSLDPSGGAARSILAAVSTRDR
HHHHHHHHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHCCCH
ATLGAAIDQAAQGQADIAPVEVMLDGAKERWGQFFVTAVADDGDAEAAIVYLLETTERRA
HHHHHHHHHHHCCCCCCCHHHHEECCHHHHCCEEEEEEEECCCCCCEEEEEEEHHHHHHH
LENQVNQAQKMDTIGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHH
TRAATLVRQLLAFSRKQTLRPQVLDLGEALTDIDRLLKRLIGEKVSLEMQHGRDLWRVKA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHH
DVSQFEQVIVNLAVNARDAMPDGGKLAIRTSNVPAAEAAQLAHKGMPAADYVRIDVSDTG
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCC
TGIPADIVDKIFEPFFSTKEVGKGTGLGLSTVYGIIKQTGGFVYVDSEPGKGTTFHIFLP
CCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEC
RHDALPEAQPDAPAPISSATTAAAKPRADMTGQGTILLVEDEEGLRSLNARGLRSRGYNV
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCHHHHHHCCCCHHHCCCEE
IEAGNGIEALEEFDAHGGAVDLVVSDVVMPEMDGPTLLKAMRARNSELKIIFVSGYAEDA
EECCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHH
FEKSLPENEQFAFLAKPFALSALVAKVKETMGAN
HHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA