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The map label for this gene is trpD [H]

Identifier: 86749914

GI number: 86749914

Start: 3188470

End: 3189495

Strand: Direct

Name: trpD [H]

Synonym: RPB_2797

Alternate gene names: 86749914

Gene position: 3188470-3189495 (Clockwise)

Preceding gene: 86749913

Following gene: 86749915

Centisome position: 59.8

GC content: 68.42

Gene sequence:

>1026_bases
ATGGGGACCATGATCGATTTCAAGGCAGTTATCGCGAAGGTCGCGACGGGGGCGTCGCTGACCAGGGACGAAGCGGCGAA
CGCGTTCGACGCGATGATGTCGGGCGACGCGACGCCGTCGCAGATGGGTGCATTGCTGATGGGCCTGCGAGTCCGCGGCG
AGACCGTCGACGAAATCACCGGCGCGGTGACGACGATGCGCGCCAAGATGCTGACGGTCGCAGCGCCGCCCGACGCGGTC
GACGTCGTCGGCACCGGCGGCGACGGCTCCGGCTCGGTCAACGTCTCGACCTGCACTTCGTTTGTCGTGGCCGGCTGCGG
CGTTCCGGTCGCCAAGCACGGCAACCGCGCGCTGTCGTCGAAATCCGGCGCCGCCGACGTGCTCAATGCCCTCGGCGTCA
AGATCGACATCACCCCGGACCACGTCGGCCGCTGCGTGGCGGAGGCCGGCATCGGCTTCATGTTCGCGCCGACGCATCAT
CCGGCGATGAAGAACGTGGGTCCTACCCGCGTCGAGCTCGCTACCCGCACGATCTTCAATCTGCTCGGGCCGCTGTCGAA
TCCCGCCGGCGTCAAGCGCCAGATGATCGGCGTGTTCTCGCGGCAATGGGTGCAGCCGCTGGCGCAGGTGCTGCAGAATC
TCGGCTCAGAATCGATCTGGGTGGTGCACGGCTCCGACGGGCTCGACGAGATCACCCTGTCCGGCCCGACCGCCGTCGCC
GAATTGAAGAACGGCGAGATCAGGACCTTCGAGATCGGCCCCGAGGACGCCGGCCTGCCCCGCGCGCCGGCCGACGCGCT
GAAGGGCGGCGATGCCGAGGCCAATGCGGTGGCGCTGCGCGCCGTGCTGGAAGGCATGCCGGGGCCGTATCGCGACGTCG
CGCTGCTCAACGCCGCGGCGACGCTGATCGTCGCCGGCAAGGCGAAGGATCTCAAGGAAGGCGTCGCGCTCGGCGCCCAA
TCGATCGACAGCGGCGCCGCCGAAGCACGTTTGAAAAAGCTGATCGCGGTATCGGCGGCCGCCTAA

Upstream 100 bases:

>100_bases
GTCGAAAAGCAGATCGGCACCAAGATCAACCAGCAGGCTGTGGCTCAGGCGACGGGGGCGGCGACCAACTGACGAAGGCA
TCCGCCTTCGCCCGTCGCCG

Downstream 100 bases:

>100_bases
GCGGGGTGAAATCGGTTCGTCATTGCGAGCGGAGCGAAGCAATCCAGAACGCGGTGCACGGAGCTGGATTGCTTCGTCGC
TTCGCTCCTCGCAATGACGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGTMIDFKAVIAKVATGASLTRDEAANAFDAMMSGDATPSQMGALLMGLRVRGETVDEITGAVTTMRAKMLTVAAPPDAV
DVVGTGGDGSGSVNVSTCTSFVVAGCGVPVAKHGNRALSSKSGAADVLNALGVKIDITPDHVGRCVAEAGIGFMFAPTHH
PAMKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMIGVFSRQWVQPLAQVLQNLGSESIWVVHGSDGLDEITLSGPTAVA
ELKNGEIRTFEIGPEDAGLPRAPADALKGGDAEANAVALRAVLEGMPGPYRDVALLNAAATLIVAGKAKDLKEGVALGAQ
SIDSGAAEARLKKLIAVSAAA

Sequences:

>Translated_341_residues
MGTMIDFKAVIAKVATGASLTRDEAANAFDAMMSGDATPSQMGALLMGLRVRGETVDEITGAVTTMRAKMLTVAAPPDAV
DVVGTGGDGSGSVNVSTCTSFVVAGCGVPVAKHGNRALSSKSGAADVLNALGVKIDITPDHVGRCVAEAGIGFMFAPTHH
PAMKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMIGVFSRQWVQPLAQVLQNLGSESIWVVHGSDGLDEITLSGPTAVA
ELKNGEIRTFEIGPEDAGLPRAPADALKGGDAEANAVALRAVLEGMPGPYRDVALLNAAATLIVAGKAKDLKEGVALGAQ
SIDSGAAEARLKKLIAVSAAA
>Mature_340_residues
GTMIDFKAVIAKVATGASLTRDEAANAFDAMMSGDATPSQMGALLMGLRVRGETVDEITGAVTTMRAKMLTVAAPPDAVD
VVGTGGDGSGSVNVSTCTSFVVAGCGVPVAKHGNRALSSKSGAADVLNALGVKIDITPDHVGRCVAEAGIGFMFAPTHHP
AMKNVGPTRVELATRTIFNLLGPLSNPAGVKRQMIGVFSRQWVQPLAQVLQNLGSESIWVVHGSDGLDEITLSGPTAVAE
LKNGEIRTFEIGPEDAGLPRAPADALKGGDAEANAVALRAVLEGMPGPYRDVALLNAAATLIVAGKAKDLKEGVALGAQS
IDSGAAEARLKKLIAVSAAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=335, Percent_Identity=39.4029850746269, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=277, Percent_Identity=32.8519855595668, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 34683; Mature: 34552

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTMIDFKAVIAKVATGASLTRDEAANAFDAMMSGDATPSQMGALLMGLRVRGETVDEIT
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
GAVTTMRAKMLTVAAPPDAVDVVGTGGDGSGSVNVSTCTSFVVAGCGVPVAKHGNRALSS
HHHHHHHHHEEEEECCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCCCHHHCCCHHHCC
KSGAADVLNALGVKIDITPDHVGRCVAEAGIGFMFAPTHHPAMKNVGPTRVELATRTIFN
CCCHHHHHHHCCCEEEECHHHHHHHHHHHCCCEEECCCCCCHHHCCCCHHHHHHHHHHHH
LLGPLSNPAGVKRQMIGVFSRQWVQPLAQVLQNLGSESIWVVHGSDGLDEITLSGPTAVA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCHHHH
ELKNGEIRTFEIGPEDAGLPRAPADALKGGDAEANAVALRAVLEGMPGPYRDVALLNAAA
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
TLIVAGKAKDLKEGVALGAQSIDSGAAEARLKKLIAVSAAA
HEEEECCCHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GTMIDFKAVIAKVATGASLTRDEAANAFDAMMSGDATPSQMGALLMGLRVRGETVDEIT
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
GAVTTMRAKMLTVAAPPDAVDVVGTGGDGSGSVNVSTCTSFVVAGCGVPVAKHGNRALSS
HHHHHHHHHEEEEECCCCCEEEEECCCCCCCCEEHHHHHHHHHHHCCCCHHHCCCHHHCC
KSGAADVLNALGVKIDITPDHVGRCVAEAGIGFMFAPTHHPAMKNVGPTRVELATRTIFN
CCCHHHHHHHCCCEEEECHHHHHHHHHHHCCCEEECCCCCCHHHCCCCHHHHHHHHHHHH
LLGPLSNPAGVKRQMIGVFSRQWVQPLAQVLQNLGSESIWVVHGSDGLDEITLSGPTAVA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCHHHH
ELKNGEIRTFEIGPEDAGLPRAPADALKGGDAEANAVALRAVLEGMPGPYRDVALLNAAA
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
TLIVAGKAKDLKEGVALGAQSIDSGAAEARLKKLIAVSAAA
HEEEECCCHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA