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The map label for this gene is ppiD [H]

Identifier: 86749913

GI number: 86749913

Start: 3186540

End: 3188441

Strand: Direct

Name: ppiD [H]

Synonym: RPB_2796

Alternate gene names: 86749913

Gene position: 3186540-3188441 (Clockwise)

Preceding gene: 86749906

Following gene: 86749914

Centisome position: 59.77

GC content: 65.93

Gene sequence:

>1902_bases
ATGCTCCGAGGAATACGCAACGCCTCATCCAATTGGGTCGGCAAGACCATCATGATGATCGTGATGGGCGTGCTGATCCT
CAGCTTTGCGGTCTGGGGCATTGCCGACATCTTCCGCGGGTTCGGCCGATCCACGCTCGCCACCATCGGCGGCACCGAGA
TCACCACCGAACAATTCCGCCAGACCTACAACGACCGTCTGCAGCAGATCGGCCGGCAGTTCGGCCGGCCGCTGACGCCG
GATCAGGCGCGTGCCTTCGGCATCGATCGCCAAGTGCTGCAGCAGGTGATCGCGGAGGCGGCGCTCGACGAGGATGCGCG
CCGGCTCGGGCTCGGCCAGTCCGACGAAGAGACCATGAAGAGCATCCTCAACGACCCGAACTTCAAGGGCGTCGGCGGTG
CGTTCGATCCGAACCGCTTCCAGCAAGTGATCCGCCAGTTCGGCTTCACCGAGCAGCGCTACATCGCCGAGCAGCGCAAG
GTCGCGCTGCGGCGGCAGATCGCCGGCACCATCACGGCCGGCCTCGCGCCGTCCAGCACGATGTTGCAGGTCGCCAGCCA
GTTCCAGAACGAGCAGCGCGCGATCGAGTATCTGAAGCTGACCGACGCGCAAGTCGGCACCATCGACCCGCCCTCGCCCG
AAGCGCTCGCGGCCTACTACGAAGACCACAAGACGCAGTTCCGCGCGCCCGAATATCGCAAGCTCGCATTCGTCACGGTG
ACCCCCGACTCGATCGCCAAATGGACCGACGTGTCCGACGCCGACGCGCGCAAATTGTTCGACCAACGCAAGGACAAGCT
TTCGACGCCGGAGAAGCGGCAGGTGTCGCAAATCGTGTTTCCCAGCGGCGAAGAGGCCCAGGCCGCGCGGACCAAGATCG
CCGAGGGCGCCTCGTTCGATGACATCGCCACTCAGCGTGGGCTGAAGCCGGCCGACGTCGAACTCGGCATGGTCAGCAAG
GCCGAAATGCTCGACCCTGCCGTCGCGAATGCCGCCTTTGCGCTGCCGCTCAACGAGGTCAGCCAGCCGATCCAGGGCGC
GTTCGGCACGGCGCTGGTCAGGGTGTCCAAGGTCGAGCCCGGCGTCCAGCCGAGCTACGAGAGCCTCGCCTCCACGATCA
AACGCGATGTCTCGCTGGAGCGCGCCCGCGCCCAGGTGCAGGAACTGCACGACAAGATGGAAGACGCCCGCGCCGGCGGC
GCCAATGTGATCGAAGCGGCCAAGACGCTCGGCCTCAACGCCGTGACCATCGAGGCGATCGACCGCTCCGGCCGCGGCCC
GGATGGCCAGCCGGTCAAGGACATCCCCCAGGGTCTCGAACTGGCGACCGCCGCGTTCAACAGCGATGTCGGCGTCGATA
CCGAATCGATCAACTATCAGAACGGCTATGTCTGGTTCGACGTGCTCGGCGTGACGCCGTCGCGCGAGCGCAGCCTCGAC
GAGGTCAAGGACCAAGTCGAAGCGCGCTGGCGCACCGAGCAGGTCACCAGCCGGCTGCGGACCATGGCCGCCGAGATGGT
GCAGAAGCTCGGCACCGCCGGCAAGCTCGCAGAAGTCGCGCCGCAGGGTGTCAAGGTCGAGACCGCCACCGGACTGAAGC
GCGAGGGAGCGAGCGCCGGCGTGCCGGATACAGTCGTCGAGGCGGTGTTCAGGACGCAGAAGGACGCGTTCGGCCAGAGC
CAGGGCGGCACCGGCAACGAATGGTTCGTGTATCGCGTCACCGACGTCACGATCCCGCCGGTCGATCTCGCCTCCGCGGA
GACGAAGAAACTCAAGGACGCGCTGGTGCAGCGGATGAACGACGAGCAGGTCGGCGAATATATCGCCTGGGTCGAAAAGC
AGATCGGCACCAAGATCAACCAGCAGGCTGTGGCTCAGGCGACGGGGGCGGCGACCAACTGA

Upstream 100 bases:

>100_bases
TGCGACCGCCACTTTATGATGGATTTTCAAGCCGGCGACGCTAATTTGCGCCACCGCGCGCCAGAGCGCGGCCGGTTCCC
TCCTGCGAAAAAGTGTGTCC

Downstream 100 bases:

>100_bases
CGAAGGCATCCGCCTTCGCCCGTCGCCGATGGGGACCATGATCGATTTCAAGGCAGTTATCGCGAAGGTCGCGACGGGGG
CGTCGCTGACCAGGGACGAA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MLRGIRNASSNWVGKTIMMIVMGVLILSFAVWGIADIFRGFGRSTLATIGGTEITTEQFRQTYNDRLQQIGRQFGRPLTP
DQARAFGIDRQVLQQVIAEAALDEDARRLGLGQSDEETMKSILNDPNFKGVGGAFDPNRFQQVIRQFGFTEQRYIAEQRK
VALRRQIAGTITAGLAPSSTMLQVASQFQNEQRAIEYLKLTDAQVGTIDPPSPEALAAYYEDHKTQFRAPEYRKLAFVTV
TPDSIAKWTDVSDADARKLFDQRKDKLSTPEKRQVSQIVFPSGEEAQAARTKIAEGASFDDIATQRGLKPADVELGMVSK
AEMLDPAVANAAFALPLNEVSQPIQGAFGTALVRVSKVEPGVQPSYESLASTIKRDVSLERARAQVQELHDKMEDARAGG
ANVIEAAKTLGLNAVTIEAIDRSGRGPDGQPVKDIPQGLELATAAFNSDVGVDTESINYQNGYVWFDVLGVTPSRERSLD
EVKDQVEARWRTEQVTSRLRTMAAEMVQKLGTAGKLAEVAPQGVKVETATGLKREGASAGVPDTVVEAVFRTQKDAFGQS
QGGTGNEWFVYRVTDVTIPPVDLASAETKKLKDALVQRMNDEQVGEYIAWVEKQIGTKINQQAVAQATGAATN

Sequences:

>Translated_633_residues
MLRGIRNASSNWVGKTIMMIVMGVLILSFAVWGIADIFRGFGRSTLATIGGTEITTEQFRQTYNDRLQQIGRQFGRPLTP
DQARAFGIDRQVLQQVIAEAALDEDARRLGLGQSDEETMKSILNDPNFKGVGGAFDPNRFQQVIRQFGFTEQRYIAEQRK
VALRRQIAGTITAGLAPSSTMLQVASQFQNEQRAIEYLKLTDAQVGTIDPPSPEALAAYYEDHKTQFRAPEYRKLAFVTV
TPDSIAKWTDVSDADARKLFDQRKDKLSTPEKRQVSQIVFPSGEEAQAARTKIAEGASFDDIATQRGLKPADVELGMVSK
AEMLDPAVANAAFALPLNEVSQPIQGAFGTALVRVSKVEPGVQPSYESLASTIKRDVSLERARAQVQELHDKMEDARAGG
ANVIEAAKTLGLNAVTIEAIDRSGRGPDGQPVKDIPQGLELATAAFNSDVGVDTESINYQNGYVWFDVLGVTPSRERSLD
EVKDQVEARWRTEQVTSRLRTMAAEMVQKLGTAGKLAEVAPQGVKVETATGLKREGASAGVPDTVVEAVFRTQKDAFGQS
QGGTGNEWFVYRVTDVTIPPVDLASAETKKLKDALVQRMNDEQVGEYIAWVEKQIGTKINQQAVAQATGAATN
>Mature_633_residues
MLRGIRNASSNWVGKTIMMIVMGVLILSFAVWGIADIFRGFGRSTLATIGGTEITTEQFRQTYNDRLQQIGRQFGRPLTP
DQARAFGIDRQVLQQVIAEAALDEDARRLGLGQSDEETMKSILNDPNFKGVGGAFDPNRFQQVIRQFGFTEQRYIAEQRK
VALRRQIAGTITAGLAPSSTMLQVASQFQNEQRAIEYLKLTDAQVGTIDPPSPEALAAYYEDHKTQFRAPEYRKLAFVTV
TPDSIAKWTDVSDADARKLFDQRKDKLSTPEKRQVSQIVFPSGEEAQAARTKIAEGASFDDIATQRGLKPADVELGMVSK
AEMLDPAVANAAFALPLNEVSQPIQGAFGTALVRVSKVEPGVQPSYESLASTIKRDVSLERARAQVQELHDKMEDARAGG
ANVIEAAKTLGLNAVTIEAIDRSGRGPDGQPVKDIPQGLELATAAFNSDVGVDTESINYQNGYVWFDVLGVTPSRERSLD
EVKDQVEARWRTEQVTSRLRTMAAEMVQKLGTAGKLAEVAPQGVKVETATGLKREGASAGVPDTVVEAVFRTQKDAFGQS
QGGTGNEWFVYRVTDVTIPPVDLASAETKKLKDALVQRMNDEQVGEYIAWVEKQIGTKINQQAVAQATGAATN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=566, Percent_Identity=25.7950530035336, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69117; Mature: 69117

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGIRNASSNWVGKTIMMIVMGVLILSFAVWGIADIFRGFGRSTLATIGGTEITTEQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
QTYNDRLQQIGRQFGRPLTPDQARAFGIDRQVLQQVIAEAALDEDARRLGLGQSDEETMK
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHH
SILNDPNFKGVGGAFDPNRFQQVIRQFGFTEQRYIAEQRKVALRRQIAGTITAGLAPSST
HHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLQVASQFQNEQRAIEYLKLTDAQVGTIDPPSPEALAAYYEDHKTQFRAPEYRKLAFVTV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TPDSIAKWTDVSDADARKLFDQRKDKLSTPEKRQVSQIVFPSGEEAQAARTKIAEGASFD
CCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
DIATQRGLKPADVELGMVSKAEMLDPAVANAAFALPLNEVSQPIQGAFGTALVRVSKVEP
HHHHHCCCCCCCCCCCCCCHHHHHCHHHHHCEEECCHHHHHHHHHHHHHHHHHHHHCCCC
GVQPSYESLASTIKRDVSLERARAQVQELHDKMEDARAGGANVIEAAKTLGLNAVTIEAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEH
DRSGRGPDGQPVKDIPQGLELATAAFNSDVGVDTESINYQNGYVWFDVLGVTPSRERSLD
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH
EVKDQVEARWRTEQVTSRLRTMAAEMVQKLGTAGKLAEVAPQGVKVETATGLKREGASAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCHHCCCCCC
VPDTVVEAVFRTQKDAFGQSQGGTGNEWFVYRVTDVTIPPVDLASAETKKLKDALVQRMN
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECEECCCCCCCHHHHHHHHHHHHHCC
DEQVGEYIAWVEKQIGTKINQQAVAQATGAATN
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLRGIRNASSNWVGKTIMMIVMGVLILSFAVWGIADIFRGFGRSTLATIGGTEITTEQFR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHH
QTYNDRLQQIGRQFGRPLTPDQARAFGIDRQVLQQVIAEAALDEDARRLGLGQSDEETMK
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHH
SILNDPNFKGVGGAFDPNRFQQVIRQFGFTEQRYIAEQRKVALRRQIAGTITAGLAPSST
HHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLQVASQFQNEQRAIEYLKLTDAQVGTIDPPSPEALAAYYEDHKTQFRAPEYRKLAFVTV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TPDSIAKWTDVSDADARKLFDQRKDKLSTPEKRQVSQIVFPSGEEAQAARTKIAEGASFD
CCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
DIATQRGLKPADVELGMVSKAEMLDPAVANAAFALPLNEVSQPIQGAFGTALVRVSKVEP
HHHHHCCCCCCCCCCCCCCHHHHHCHHHHHCEEECCHHHHHHHHHHHHHHHHHHHHCCCC
GVQPSYESLASTIKRDVSLERARAQVQELHDKMEDARAGGANVIEAAKTLGLNAVTIEAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEH
DRSGRGPDGQPVKDIPQGLELATAAFNSDVGVDTESINYQNGYVWFDVLGVTPSRERSLD
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH
EVKDQVEARWRTEQVTSRLRTMAAEMVQKLGTAGKLAEVAPQGVKVETATGLKREGASAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCHHCCCCCC
VPDTVVEAVFRTQKDAFGQSQGGTGNEWFVYRVTDVTIPPVDLASAETKKLKDALVQRMN
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECEECCCCCCCHHHHHHHHHHHHHCC
DEQVGEYIAWVEKQIGTKINQQAVAQATGAATN
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]