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The map label for this gene is lepB [H]

Identifier: 86749729

GI number: 86749729

Start: 2995098

End: 2995856

Strand: Direct

Name: lepB [H]

Synonym: RPB_2611

Alternate gene names: 86749729

Gene position: 2995098-2995856 (Clockwise)

Preceding gene: 86749728

Following gene: 86749730

Centisome position: 56.18

GC content: 62.06

Gene sequence:

>759_bases
ATGAGCGTGACATCCGGTACGAAATCTGAAAGCGGCATCGGCGAAACGATCCGCGTCGTCATTCACGCGCTCATCATCGC
ACTGGTGATCCGGACTTTTCTGTTCCAGCCGTTCAACATCCCGTCCGGATCAATGAAGGCGACGCTGCTGGTCGGCGACT
ATCTGTTCGTGTCGAAATATTCCTACGGCTACAGCCATTATTCGATCCCGTTCTCGCCGCCGATCTTCTCCGGCCGGATC
TTCGGCTCGGAGCCGAACCGCGGCGACGTCGTGGTGTTCCGGCTGCCGAAGGACGACTCCACCGACTACATCAAGCGCGT
CATCGGCCTGCCCGGCGACCGCATCCAGATGCGCGAGGGGCTGCTCTACATCAACGACAAGCCGGTGGTGCGCGAGCGGC
TGCCCGACTACGTCGGCGAGGACCCGTGCGGCTCGGACGCCACCGCCCGCGTCAAGCGCTGGAAGGAGACGCTGCCGAAC
AACGTCTCCTACGAGACGCTCGATTGCGTCGACAACGGCTTCTACGACAACACCAATGTCTACACGGTGCCGCCCGGCAA
CTTCTTCATGATGGGCGACAACCGCGACAATTCCACCGACAGCCGCGTGCTGTCCGCGGTCGGCTACGTGCCGTTCCAGA
ACATCATCGGCCGCGCCCAGATGATCTTCTTCTCGATCGCCGAGGGTGAACACGCTTGGCAGATCTGGCGCTGGCCGACC
GCGGTGCGCTGGAGCCGCATCTTTTCGATCGTGCGATGA

Upstream 100 bases:

>100_bases
GCCTTCGCCTCTCCAGCAGTGTCTCATCGCGAAGCGGTTCCGCTTCACCTGAGAACAGTCGTCCACCGCGCGGCCGCCCG
CGACGGGAATCGGGAAAGCG

Downstream 100 bases:

>100_bases
TCGAGGATGTGACCAGCATCGACAGTCCGCCGATGGCCAGCGATCCGGCTGGGTCGGAGCAGCCGGCCGAGCAGCCTGCC
GGCCGCAAGCGGCGCAGCAA

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSVTSGTKSESGIGETIRVVIHALIIALVIRTFLFQPFNIPSGSMKATLLVGDYLFVSKYSYGYSHYSIPFSPPIFSGRI
FGSEPNRGDVVVFRLPKDDSTDYIKRVIGLPGDRIQMREGLLYINDKPVVRERLPDYVGEDPCGSDATARVKRWKETLPN
NVSYETLDCVDNGFYDNTNVYTVPPGNFFMMGDNRDNSTDSRVLSAVGYVPFQNIIGRAQMIFFSIAEGEHAWQIWRWPT
AVRWSRIFSIVR

Sequences:

>Translated_252_residues
MSVTSGTKSESGIGETIRVVIHALIIALVIRTFLFQPFNIPSGSMKATLLVGDYLFVSKYSYGYSHYSIPFSPPIFSGRI
FGSEPNRGDVVVFRLPKDDSTDYIKRVIGLPGDRIQMREGLLYINDKPVVRERLPDYVGEDPCGSDATARVKRWKETLPN
NVSYETLDCVDNGFYDNTNVYTVPPGNFFMMGDNRDNSTDSRVLSAVGYVPFQNIIGRAQMIFFSIAEGEHAWQIWRWPT
AVRWSRIFSIVR
>Mature_251_residues
SVTSGTKSESGIGETIRVVIHALIIALVIRTFLFQPFNIPSGSMKATLLVGDYLFVSKYSYGYSHYSIPFSPPIFSGRIF
GSEPNRGDVVVFRLPKDDSTDYIKRVIGLPGDRIQMREGLLYINDKPVVRERLPDYVGEDPCGSDATARVKRWKETLPNN
VSYETLDCVDNGFYDNTNVYTVPPGNFFMMGDNRDNSTDSRVLSAVGYVPFQNIIGRAQMIFFSIAEGEHAWQIWRWPTA
VRWSRIFSIVR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=278, Percent_Identity=35.2517985611511, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28532; Mature: 28401

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTSGTKSESGIGETIRVVIHALIIALVIRTFLFQPFNIPSGSMKATLLVGDYLFVSKY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECEEEEEEE
SYGYSHYSIPFSPPIFSGRIFGSEPNRGDVVVFRLPKDDSTDYIKRVIGLPGDRIQMREG
CCCCEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHCCC
LLYINDKPVVRERLPDYVGEDPCGSDATARVKRWKETLPNNVSYETLDCVDNGFYDNTNV
EEEECCCCHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEE
YTVPPGNFFMMGDNRDNSTDSRVLSAVGYVPFQNIIGRAQMIFFSIAEGEHAWQIWRWPT
EEECCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCCEEEEEECCC
AVRWSRIFSIVR
HHHHHHHHHHCC
>Mature Secondary Structure 
SVTSGTKSESGIGETIRVVIHALIIALVIRTFLFQPFNIPSGSMKATLLVGDYLFVSKY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECEEEEEEE
SYGYSHYSIPFSPPIFSGRIFGSEPNRGDVVVFRLPKDDSTDYIKRVIGLPGDRIQMREG
CCCCEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHCCC
LLYINDKPVVRERLPDYVGEDPCGSDATARVKRWKETLPNNVSYETLDCVDNGFYDNTNV
EEEECCCCHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEE
YTVPPGNFFMMGDNRDNSTDSRVLSAVGYVPFQNIIGRAQMIFFSIAEGEHAWQIWRWPT
EEECCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCCEEEEEECCC
AVRWSRIFSIVR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]