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The map label for this gene is acpS

Identifier: 86749728

GI number: 86749728

Start: 2994427

End: 2994852

Strand: Direct

Name: acpS

Synonym: RPB_2610

Alternate gene names: 86749728

Gene position: 2994427-2994852 (Clockwise)

Preceding gene: 86749727

Following gene: 86749729

Centisome position: 56.16

GC content: 66.67

Gene sequence:

>426_bases
ATGATCATCGGAATCGGCTCCGACCTGATCGACATTACCCGGATCGCCAAGGTGATCGACCGGCATGGGGAACGGTTTCT
CGACCGCATCTTCACCGAAACCGAGCAGGCGAGGGCCGGGCGGCGGGACAAGCAACCGAATCTGGTGGCCGCCACCTACG
CCAAGCGGTTCGCCGCCAAGGAGGCGTGTTCCAAGGCGCTCGGAACCGGGATTCGCCAGGGCGTCTGGTGGCGCGACATG
GGGGTGGTCAATCAGCGCGGCGGCCGGCCGACCATGCTGCTGACCGGCGGAGCCAGGGCGCGGCTCGACGCCCTGACGCC
GCCCGGAATGACGGCGCAGATCGATCTTTCGATCACGGATGAATGGCCGCTGGCCCAGGCCTTCGTGGTCATTTCCGCGA
TTCCCGCGGCCACCTCCGGCACTTGA

Upstream 100 bases:

>100_bases
GCTTCTACATGATCGGCGAGGCGCTGTTCGTCGGCCTCGGCGAAACGGTGAAGGCGATGCGGTCGGCGATGGACCGTGGC
CGTGCCAGGGTGATCGCGGC

Downstream 100 bases:

>100_bases
AAGAGCGTCGGCGCCACAGGAAAAGAGGCTTATACGTCATAGGATTAGCGAGTTTTGTCGGGACGGTTGATTGCGCGCTT
GCCGACAACGGTCTACAACC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAKEACSKALGTGIRQGVWWRDM
GVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITDEWPLAQAFVVISAIPAATSGT

Sequences:

>Translated_141_residues
MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAKEACSKALGTGIRQGVWWRDM
GVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITDEWPLAQAFVVISAIPAATSGT
>Mature_141_residues
MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAKEACSKALGTGIRQGVWWRDM
GVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITDEWPLAQAFVVISAIPAATSGT

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=132, Percent_Identity=36.3636363636364, Blast_Score=73, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_RHOP2 (Q2IWU7)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486224.1
- ProteinModelPortal:   Q2IWU7
- SMR:   Q2IWU7
- STRING:   Q2IWU7
- GeneID:   3910402
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2610
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   RPAL316058:RPB_2610-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15277; Mature: 15277

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAK
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EACSKALGTGIRQGVWWRDMGVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITD
HHHHHHHHHHHHCCCCHHHCCCHHCCCCCCEEEEECCCCEEECCCCCCCCEEEEEEEECC
EWPLAQAFVVISAIPAATSGT
CCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAK
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EACSKALGTGIRQGVWWRDMGVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITD
HHHHHHHHHHHHCCCCHHHCCCHHCCCCCCEEEEECCCCEEECCCCCCCCEEEEEEEECC
EWPLAQAFVVISAIPAATSGT
CCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA