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The map label for this gene is paaG [C]

Identifier: 86749245

GI number: 86749245

Start: 2416140

End: 2417069

Strand: Reverse

Name: paaG [C]

Synonym: RPB_2124

Alternate gene names: 86749245

Gene position: 2417069-2416140 (Counterclockwise)

Preceding gene: 86749246

Following gene: 86749236

Centisome position: 45.33

GC content: 65.91

Gene sequence:

>930_bases
ATGACGATTCATAAACAAGAACACGCTGGAGGAAACCAGATGCCGTTCGAGACGATCAAATACGAGGTCGCCGAGCAGAT
TCTCACCATCACGCTGAACCGGCCGGAGAAGCTCAACGCGTTCAACCCGGCGATGCAGCGCGAGCTGATCGAGGCGTTCG
ACAGGGCCGATGCCGACGACGATATTCGCGCCGTGATCGTCACCGGCGAAGGCCGTGCGTTCTGTGCCGGCGCCGATCTG
TCGTCCGGCGCCGACACCTTCGATCGCGACGCCCGCCGCGGCCCGGTGCGGCGCAATGCCGACGGTTCGGTCGACTACGC
CGACCCGCAGGTGCGCGACGGCGGCGGCCAGGTGACGCTGCGGATCTTCAAATGCCTGAAGCCGGTGATCGCGGCCGTCA
ACGGCCCCGCGGTCGGCATCGGCGTCACCATGCAGCTGGCGATGGACATCCGCATTGCCTCCGAAGCCGCGCGGTTCGGC
TTCGTGTTCTCGCAGCGTGGCATCGTGCCGGAGGCCGCCTCGAGCTGGTTCCTGCCGCGCATCGTCGGCATCGCTCAGGC
TTTGGAGTGGTGCTACACCGGCCGCGTGTTCCCGGCGCAGGAAGCGCTCGACGGCAAGCTCGTCAGCCGCGTGGTGCCGG
CCGATCAGTTACTCGCGACCGCGCGCACGCTGGCCAAGGAGATCGCCGCCAAGACCGCGCCGGTGTCGGTGGCACTGATC
CGGCAGATGATGTGGCGGATGCTCGGCGCCGACGATCCGATGGAAGCCCACAAGATCGACAGCCGCGGCATCTACGAGCG
CGGCCGCTCCGACGACGTCAAGGAAGGCGTCAGCTCGTTCCTGGAGAAACGCCCGGCGCAGTTCAAGAACAAGGTGACGA
GCGACATGCCGGCGTATTTCCCGTGGTGGGACGAACGGGAATACAAGTAA

Upstream 100 bases:

>100_bases
CGCTAGGCACGCGTTTCGCCGCACGCACGGTGTCATGCGCGGGCTCGACCCGCGCATCCATCTCCTTCATAAAGGATGGA
TGGCCGGGTCAAGCCCGGCC

Downstream 100 bases:

>100_bases
GCGGCAAGCGCGCTCATCGAGCGGACCGGCAACAATCGCCGTCATTCCGGGGCGCGAGCGCCAGCTCGCGAACCCGGAAT
CTCGCCGTGCTAGTGACACC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTIHKQEHAGGNQMPFETIKYEVAEQILTITLNRPEKLNAFNPAMQRELIEAFDRADADDDIRAVIVTGEGRAFCAGADL
SSGADTFDRDARRGPVRRNADGSVDYADPQVRDGGGQVTLRIFKCLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFG
FVFSQRGIVPEAASSWFLPRIVGIAQALEWCYTGRVFPAQEALDGKLVSRVVPADQLLATARTLAKEIAAKTAPVSVALI
RQMMWRMLGADDPMEAHKIDSRGIYERGRSDDVKEGVSSFLEKRPAQFKNKVTSDMPAYFPWWDEREYK

Sequences:

>Translated_309_residues
MTIHKQEHAGGNQMPFETIKYEVAEQILTITLNRPEKLNAFNPAMQRELIEAFDRADADDDIRAVIVTGEGRAFCAGADL
SSGADTFDRDARRGPVRRNADGSVDYADPQVRDGGGQVTLRIFKCLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFG
FVFSQRGIVPEAASSWFLPRIVGIAQALEWCYTGRVFPAQEALDGKLVSRVVPADQLLATARTLAKEIAAKTAPVSVALI
RQMMWRMLGADDPMEAHKIDSRGIYERGRSDDVKEGVSSFLEKRPAQFKNKVTSDMPAYFPWWDEREYK
>Mature_308_residues
TIHKQEHAGGNQMPFETIKYEVAEQILTITLNRPEKLNAFNPAMQRELIEAFDRADADDDIRAVIVTGEGRAFCAGADLS
SGADTFDRDARRGPVRRNADGSVDYADPQVRDGGGQVTLRIFKCLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGF
VFSQRGIVPEAASSWFLPRIVGIAQALEWCYTGRVFPAQEALDGKLVSRVVPADQLLATARTLAKEIAAKTAPVSVALIR
QMMWRMLGADDPMEAHKIDSRGIYERGRSDDVKEGVSSFLEKRPAQFKNKVTSDMPAYFPWWDEREYK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=265, Percent_Identity=31.3207547169811, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI45643119, Length=278, Percent_Identity=32.7338129496403, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260275230, Length=278, Percent_Identity=32.7338129496403, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260274832, Length=278, Percent_Identity=32.7338129496403, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI70995211, Length=248, Percent_Identity=35.0806451612903, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=29.1187739463602, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI116235487, Length=213, Percent_Identity=31.4553990610329, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI221307494, Length=209, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI221136756, Length=209, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI221136753, Length=209, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4757968, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI25453481, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI51538573, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4757966, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI51538581, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=198, Percent_Identity=28.2828282828283, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4502327, Length=272, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=27.741935483871, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=27.741935483871, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787660, Length=283, Percent_Identity=36.7491166077738, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787659, Length=268, Percent_Identity=31.7164179104478, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI221142681, Length=280, Percent_Identity=32.8571428571429, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788597, Length=277, Percent_Identity=29.6028880866426, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082183, Length=291, Percent_Identity=26.1168384879725, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788682, Length=236, Percent_Identity=26.271186440678, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=278, Percent_Identity=32.3741007194245, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=263, Percent_Identity=32.319391634981, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=258, Percent_Identity=29.4573643410853, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560910, Length=205, Percent_Identity=34.6341463414634, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17549921, Length=230, Percent_Identity=33.9130434782609, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17534483, Length=232, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=220, Percent_Identity=33.6363636363636, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=32.1266968325792, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=264, Percent_Identity=26.1363636363636, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=216, Percent_Identity=27.3148148148148, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI20129971, Length=282, Percent_Identity=33.6879432624113, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653477, Length=282, Percent_Identity=33.6879432624113, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24654903, Length=207, Percent_Identity=31.4009661835749, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920382, Length=239, Percent_Identity=32.6359832635983, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357171, Length=215, Percent_Identity=29.7674418604651, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24653139, Length=271, Percent_Identity=30.9963099630996, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24650670, Length=230, Percent_Identity=28.695652173913, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 34151; Mature: 34020

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHKQEHAGGNQMPFETIKYEVAEQILTITLNRPEKLNAFNPAMQRELIEAFDRADADD
CCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCC
DIRAVIVTGEGRAFCAGADLSSGADTFDRDARRGPVRRNADGSVDYADPQVRDGGGQVTL
CCEEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCHHHH
RIFKCLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAASSWFLPR
HHHHHHHHHHHHCCCCCEEHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IVGIAQALEWCYTGRVFPAQEALDGKLVSRVVPADQLLATARTLAKEIAAKTAPVSVALI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQMMWRMLGADDPMEAHKIDSRGIYERGRSDDVKEGVSSFLEKRPAQFKNKVTSDMPAYF
HHHHHHHHCCCCCHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
PWWDEREYK
CCCCCCCCC
>Mature Secondary Structure 
TIHKQEHAGGNQMPFETIKYEVAEQILTITLNRPEKLNAFNPAMQRELIEAFDRADADD
CCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCC
DIRAVIVTGEGRAFCAGADLSSGADTFDRDARRGPVRRNADGSVDYADPQVRDGGGQVTL
CCEEEEEECCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCHHHH
RIFKCLKPVIAAVNGPAVGIGVTMQLAMDIRIASEAARFGFVFSQRGIVPEAASSWFLPR
HHHHHHHHHHHHCCCCCEEHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IVGIAQALEWCYTGRVFPAQEALDGKLVSRVVPADQLLATARTLAKEIAAKTAPVSVALI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RQMMWRMLGADDPMEAHKIDSRGIYERGRSDDVKEGVSSFLEKRPAQFKNKVTSDMPAYF
HHHHHHHHCCCCCHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
PWWDEREYK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA