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The map label for this gene is ywlC [H]

Identifier: 86748257

GI number: 86748257

Start: 1300762

End: 1301751

Strand: Reverse

Name: ywlC [H]

Synonym: RPB_1132

Alternate gene names: 86748257

Gene position: 1301751-1300762 (Counterclockwise)

Preceding gene: 86748258

Following gene: 86748256

Centisome position: 24.42

GC content: 74.85

Gene sequence:

>990_bases
ATGACCCTCGATTTGCACACCAGGACCCTGCCCGCCGGGGACGCCGCCGCTTTGGCGGCCGCAGACGTCTTGCGCGGCGG
CGGATTGATCGGATTCCCGACCGAAACCGTCTATGGGCTCGGCGCCGACGCCGCCGCTCCGGCGGCGGTGGCCCGGCTCT
ACGCCGCCAAGGGCCGGCCGTCGTTCAATCCGCTGATCGCCCACGTCGCGAATCTCGACGCCGCGCGAAAAATCGCCCGA
TTCGATTCGCGTGCGTCGGCGCTGGCGGCGGCATTCTGGCCGGGGCCGCTGACGCTGGTGCTGCCGAAGGCGGAGGAGTG
CACGGTGTGCGACCTCGCGACCGCCGGGCTCGACAGCGTCGCGGTGCGGATTCCGGCGCATCCGGTGGCGCAGGCGATCC
TGCGCGCATTCGGCGGCGCGGTGGTGGCGCCGTCCGCCAATCGCTCCGGCCATGTCTCGCCGACCACGGCCGCGCATGTC
CGCGCCGATCTCGACGGCCGGATCGATCTGATCGTCGATGGCGGCGCCGTCGACGTGGGGGTCGAATCGACCATCGTGAG
CTGCCTCGGCGCGCCGGCGCTGCTGCGCCCCGGCGGCGTGCCGCGCGAGGCGATCGAGCGCCTGCTCGGCTGCGCGCTGG
CGGACCCGTCGCCCGCTGCGGCCGGCGAGCACGCCCCGCTGGCGCCGGGGATGCTGGCGTCGCATTACGCCCCGCGCGCC
CAGGTGCGGCTGGACGCAGGCGAGGTCCGCCCCGGCGAAGCGCTGCTGGCCTTCGGGCCCGCCGCGCTCCCCGGCGCCGA
GACGGCCTGCGCGACTCGGAACCTGTCGCCGGCCGCAGATCTGACCGAGGCGGCGGCGAACCTGTTCGGGTTTTTGCGCG
AGCTCGACGCCGGTGGCGCGCGCGTGATCGCGGTGATGCCGATCCCGCCGCACGGCCTCGGCGAGGCGATCAACGACCGG
CTGCGCCGCGCCGCGGCGCCGCGGGATTGA

Upstream 100 bases:

>100_bases
CGCAGTGCTCTACCGGGCTGAGCCACACTCCGACAAGAGGCCGGCTTATAGCGTCGACCTTCGCCCTTCGCAAGCGGGCG
AATTGCGATATGAACGGCGG

Downstream 100 bases:

>100_bases
TCGCGCCGCCATTGTGGTGAAGTGTCGGCCCGCAGCTCCCGCCGCGACGGGAGGAGCTCAAACACCAGGCTCGACGGACA
ACGCCCATGACCATCGCCAA

Product: Sua5/YciO/YrdC/YwlC

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTLDLHTRTLPAGDAAALAAADVLRGGGLIGFPTETVYGLGADAAAPAAVARLYAAKGRPSFNPLIAHVANLDAARKIAR
FDSRASALAAAFWPGPLTLVLPKAEECTVCDLATAGLDSVAVRIPAHPVAQAILRAFGGAVVAPSANRSGHVSPTTAAHV
RADLDGRIDLIVDGGAVDVGVESTIVSCLGAPALLRPGGVPREAIERLLGCALADPSPAAAGEHAPLAPGMLASHYAPRA
QVRLDAGEVRPGEALLAFGPAALPGAETACATRNLSPAADLTEAAANLFGFLRELDAGGARVIAVMPIPPHGLGEAINDR
LRRAAAPRD

Sequences:

>Translated_329_residues
MTLDLHTRTLPAGDAAALAAADVLRGGGLIGFPTETVYGLGADAAAPAAVARLYAAKGRPSFNPLIAHVANLDAARKIAR
FDSRASALAAAFWPGPLTLVLPKAEECTVCDLATAGLDSVAVRIPAHPVAQAILRAFGGAVVAPSANRSGHVSPTTAAHV
RADLDGRIDLIVDGGAVDVGVESTIVSCLGAPALLRPGGVPREAIERLLGCALADPSPAAAGEHAPLAPGMLASHYAPRA
QVRLDAGEVRPGEALLAFGPAALPGAETACATRNLSPAADLTEAAANLFGFLRELDAGGARVIAVMPIPPHGLGEAINDR
LRRAAAPRD
>Mature_328_residues
TLDLHTRTLPAGDAAALAAADVLRGGGLIGFPTETVYGLGADAAAPAAVARLYAAKGRPSFNPLIAHVANLDAARKIARF
DSRASALAAAFWPGPLTLVLPKAEECTVCDLATAGLDSVAVRIPAHPVAQAILRAFGGAVVAPSANRSGHVSPTTAAHVR
ADLDGRIDLIVDGGAVDVGVESTIVSCLGAPALLRPGGVPREAIERLLGCALADPSPAAAGEHAPLAPGMLASHYAPRAQ
VRLDAGEVRPGEALLAFGPAALPGAETACATRNLSPAADLTEAAANLFGFLRELDAGGARVIAVMPIPPHGLGEAINDRL
RRAAAPRD

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=196, Percent_Identity=32.6530612244898, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367210, Length=150, Percent_Identity=36, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17537239, Length=204, Percent_Identity=31.8627450980392, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=382, Percent_Identity=35.8638743455497, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI78707274, Length=186, Percent_Identity=30.1075268817204, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33176; Mature: 33045

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLHTRTLPAGDAAALAAADVLRGGGLIGFPTETVYGLGADAAAPAAVARLYAAKGRP
CEEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCHHHEECCCCHHHHHHHHHHHHHCCCC
SFNPLIAHVANLDAARKIARFDSRASALAAAFWPGPLTLVLPKAEECTVCDLATAGLDSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHHHHCCCCCE
AVRIPAHPVAQAILRAFGGAVVAPSANRSGHVSPTTAAHVRADLDGRIDLIVDGGAVDVG
EEECCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHEEECCCCCEEEEEECCEEECC
VESTIVSCLGAPALLRPGGVPREAIERLLGCALADPSPAAAGEHAPLAPGMLASHYAPRA
HHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCC
QVRLDAGEVRPGEALLAFGPAALPGAETACATRNLSPAADLTEAAANLFGFLRELDAGGA
EEEECCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RVIAVMPIPPHGLGEAINDRLRRAAAPRD
EEEEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLDLHTRTLPAGDAAALAAADVLRGGGLIGFPTETVYGLGADAAAPAAVARLYAAKGRP
EEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCHHHEECCCCHHHHHHHHHHHHHCCCC
SFNPLIAHVANLDAARKIARFDSRASALAAAFWPGPLTLVLPKAEECTVCDLATAGLDSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHHHHCCCCCE
AVRIPAHPVAQAILRAFGGAVVAPSANRSGHVSPTTAAHVRADLDGRIDLIVDGGAVDVG
EEECCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHEEECCCCCEEEEEECCEEECC
VESTIVSCLGAPALLRPGGVPREAIERLLGCALADPSPAAAGEHAPLAPGMLASHYAPRA
HHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCC
QVRLDAGEVRPGEALLAFGPAALPGAETACATRNLSPAADLTEAAANLFGFLRELDAGGA
EEEECCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RVIAVMPIPPHGLGEAINDRLRRAAAPRD
EEEEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]